Parent-mediated intervention in infants with an elevated likelihood for autism reduces dwell time during a gaze-following task / Rachael BEDFORD in Autism Research, 17-11 (November 2024)  

Public ISBD [article]  inAutism Research > 17-11 (November 2024) . - p.2346-2354 Titre : Parent-mediated intervention in infants with an elevated likelihood for autism reduces dwell time during a gaze-following task Type de document : Texte imprimé et/ou numérique Auteurs : Rachael BEDFORD, Auteur ; Jonathan GREEN, Auteur ; Teodora GLIGA, Auteur ; Emily H. JONES, Auteur ; Mayada ELSABBAGH, Auteur ; Greg PASCO, Auteur ; Ming Wai WAN, Auteur ; Vicky SLONIMS, Auteur ; Tony CHARMAN, Auteur ; Andrew PICKLES, Auteur ; Mark H. JOHNSON, Auteur ; Basis Team THE, Auteur Article en page(s) : p.2346-2354 Langues : Anglais (eng) Mots-clés : autism  elevated likelihood for autism  gaze following  infant siblings  intervention  parent-mediated intervention  RCT Index. décimale : PER Périodiques Résumé : Abstract Cognitive markers may in theory be more sensitive to the effects of intervention than overt behavioral measures. The current study tests the impact of the Intervention with the British Autism Study of Infant Siblings?Video Interaction for Promoting Positive Parenting (iBASIS-VIPP) on an eye-tracking measure of social attention: dwell time to the referred object in a gaze following task. The original two-site, two-arm, assessor-blinded randomized controlled trial (RCT) of this intervention to increase parental awareness, and responsiveness to their infant, was run with infants who have an elevated familial likelihood for autism (EL). Fifty-four EL infants (28 iBASIS-VIPP intervention, 26 no intervention) were enrolled, and the intervention took place between 9?months (baseline) and 15?months (endpoint), with gaze following behavior measured at 15?months. Secondary intention to treat (ITT) analysis showed that the intervention was associated with significantly reduced dwell time to the referent of another person's gaze (??=??0.32, SE?=?0.14, p?=?0.03) at 15-month treatment endpoint. Given the established link between gaze following and language, the results are considered in the context of a previously reported, non-significant and transient trend toward lower language scores at the treatment endpoint (Green et al. (2015) The Lancet Psychiatry, 2(2), 133?140). Future intervention trials should aim to include experimental cognitive measures, alongside behavioral measures, to investigate mechanisms associated with intervention effects. En ligne : https://doi.org/10.1002/aur.3223 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542 [article] Parent-mediated intervention in infants with an elevated likelihood for autism reduces dwell time during a gaze-following task [Texte imprimé et/ou numérique] / Rachael BEDFORD, Auteur ; Jonathan GREEN, Auteur ; Teodora GLIGA, Auteur ; Emily H. JONES, Auteur ; Mayada ELSABBAGH, Auteur ; Greg PASCO, Auteur ; Ming Wai WAN, Auteur ; Vicky SLONIMS, Auteur ; Tony CHARMAN, Auteur ; Andrew PICKLES, Auteur ; Mark H. JOHNSON, Auteur ; Basis Team THE, Auteur . - p.2346-2354. Langues : Anglais (eng) in Autism Research > 17-11 (November 2024) . - p.2346-2354 Mots-clés : autism  elevated likelihood for autism  gaze following  infant siblings  intervention  parent-mediated intervention  RCT Index. décimale : PER Périodiques Résumé : Abstract Cognitive markers may in theory be more sensitive to the effects of intervention than overt behavioral measures. The current study tests the impact of the Intervention with the British Autism Study of Infant Siblings?Video Interaction for Promoting Positive Parenting (iBASIS-VIPP) on an eye-tracking measure of social attention: dwell time to the referred object in a gaze following task. The original two-site, two-arm, assessor-blinded randomized controlled trial (RCT) of this intervention to increase parental awareness, and responsiveness to their infant, was run with infants who have an elevated familial likelihood for autism (EL). Fifty-four EL infants (28 iBASIS-VIPP intervention, 26 no intervention) were enrolled, and the intervention took place between 9?months (baseline) and 15?months (endpoint), with gaze following behavior measured at 15?months. Secondary intention to treat (ITT) analysis showed that the intervention was associated with significantly reduced dwell time to the referent of another person's gaze (??=??0.32, SE?=?0.14, p?=?0.03) at 15-month treatment endpoint. Given the established link between gaze following and language, the results are considered in the context of a previously reported, non-significant and transient trend toward lower language scores at the treatment endpoint (Green et al. (2015) The Lancet Psychiatry, 2(2), 133?140). Future intervention trials should aim to include experimental cognitive measures, alongside behavioral measures, to investigate mechanisms associated with intervention effects. En ligne : https://doi.org/10.1002/aur.3223 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542

Quality of interaction between at-risk infants and caregiver at 12–15 months is associated with 3-year autism outcome / Ming Wai WAN in Journal of Child Psychology and Psychiatry, 54-7 (July 2013)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 54-7 (July 2013) . - p.763-771 Titre : Quality of interaction between at-risk infants and caregiver at 12–15 months is associated with 3-year autism outcome Type de document : Texte imprimé et/ou numérique Auteurs : Ming Wai WAN, Auteur ; Jonathan GREEN, Auteur ; Mayada ELSABBAGH, Auteur ; Mark H. JOHNSON, Auteur ; Tony CHARMAN, Auteur ; Faye PLUMMER, Auteur ; Basis Team THE, Auteur Article en page(s) : p.763-771 Langues : Anglais (eng) Mots-clés : ASD siblings  mother–child relations  high-risk infants  parent sensitivity Index. décimale : PER Périodiques Résumé : Background: Recent models of the early emergence of autism spectrum disorder (ASD) propose that infant intrinsic risk susceptibilities in behaviour may be amplified by interaction within the early social environment into an increasingly atypical developmental trajectory. This study examines whether 6- and 12-month parent–infant interactions in at-risk siblings differ from those with low-risk and whether – in at-risk siblings – such interactions predict later 3-year classification of ASD or no ASD. Method: Within the British Autism Study of Infant Siblings (BASIS), 6-min videotaped episodes of parent–infant free play in infants at 6–10 months (45 at-risk siblings and 47 low-risk siblings) and 12–15 months (43 at-risk siblings and 48 low-risk siblings) in a laboratory setting were rated on the Manchester Assessment of Caregiver-Infant Interaction (MACI), blind to participant information. Standard tests were administered for concurrent behavioural signs of ASD features and developmental level. Systematic consensus diagnostic classification of ASD was made at 3 years for the at-risk siblings. Results: Parent nondirectiveness and sensitive responsiveness differed in relation to ASD/risk status (at-risk ASD, at-risk no-ASD and low-risk) at both 6 and 12 months. At 6 months, infant liveliness was lower in the at-risk groups; at 12 months, infant attentiveness to parent and positive affect were lower in the at-risk group later diagnosed with ASD. Dyadic mutuality and intensity of engagement showed a group effect at 12 months. Dyadic mutuality, infant positive affect and infant attentiveness to parent at 12 months (but not 6 months) predicted 3-year ASD outcome, whereas infant ASD-related behavioural atypicality did not. Conclusions: This is the first prospective evidence that early dyadic interaction between at-risk infants and their parents is associated with later diagnostic outcome in ASD. Possible explanations for these findings and their theoretical implications are considered. En ligne : http://dx.doi.org/10.1111/jcpp.12032 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=203 [article] Quality of interaction between at-risk infants and caregiver at 12–15 months is associated with 3-year autism outcome [Texte imprimé et/ou numérique] / Ming Wai WAN, Auteur ; Jonathan GREEN, Auteur ; Mayada ELSABBAGH, Auteur ; Mark H. JOHNSON, Auteur ; Tony CHARMAN, Auteur ; Faye PLUMMER, Auteur ; Basis Team THE, Auteur . - p.763-771. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 54-7 (July 2013) . - p.763-771 Mots-clés : ASD siblings  mother–child relations  high-risk infants  parent sensitivity Index. décimale : PER Périodiques Résumé : Background: Recent models of the early emergence of autism spectrum disorder (ASD) propose that infant intrinsic risk susceptibilities in behaviour may be amplified by interaction within the early social environment into an increasingly atypical developmental trajectory. This study examines whether 6- and 12-month parent–infant interactions in at-risk siblings differ from those with low-risk and whether – in at-risk siblings – such interactions predict later 3-year classification of ASD or no ASD. Method: Within the British Autism Study of Infant Siblings (BASIS), 6-min videotaped episodes of parent–infant free play in infants at 6–10 months (45 at-risk siblings and 47 low-risk siblings) and 12–15 months (43 at-risk siblings and 48 low-risk siblings) in a laboratory setting were rated on the Manchester Assessment of Caregiver-Infant Interaction (MACI), blind to participant information. Standard tests were administered for concurrent behavioural signs of ASD features and developmental level. Systematic consensus diagnostic classification of ASD was made at 3 years for the at-risk siblings. Results: Parent nondirectiveness and sensitive responsiveness differed in relation to ASD/risk status (at-risk ASD, at-risk no-ASD and low-risk) at both 6 and 12 months. At 6 months, infant liveliness was lower in the at-risk groups; at 12 months, infant attentiveness to parent and positive affect were lower in the at-risk group later diagnosed with ASD. Dyadic mutuality and intensity of engagement showed a group effect at 12 months. Dyadic mutuality, infant positive affect and infant attentiveness to parent at 12 months (but not 6 months) predicted 3-year ASD outcome, whereas infant ASD-related behavioural atypicality did not. Conclusions: This is the first prospective evidence that early dyadic interaction between at-risk infants and their parents is associated with later diagnostic outcome in ASD. Possible explanations for these findings and their theoretical implications are considered. En ligne : http://dx.doi.org/10.1111/jcpp.12032 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=203

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