18 recherche sur le mot-clé 'RCT'

A pilot RCT of virtual reality job interview training in transition-age youth on the autism spectrum / Helen M. GENOVA in Research in Autism Spectrum Disorders, 89 (November 2021)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 89 (November 2021) . - 101878 Titre : A pilot RCT of virtual reality job interview training in transition-age youth on the autism spectrum Type de document : texte imprimé Auteurs : Helen M. GENOVA, Auteur ; Katie LANCASTER, Auteur ; James MORECRAFT, Auteur ; Mikayla HAAS, Auteur ; Alexandra EDWARDS, Auteur ; Michael DIBENEDETTO, Auteur ; Denise KRCH, Auteur ; John DELUCA, Auteur ; Matthew J. SMITH, Auteur Article en page(s) : 101878 Langues : Anglais (eng) Mots-clés : Autism  Transition age youth  Adolescents  Job interview  Virtual reality  RCT Index. décimale : PER Périodiques Résumé : Background Adolescents on the autism spectrum may have difficulty obtaining and maintaining employment. One particular obstacle for adolescents on the autism spectrum is the job interview. The purpose of the current pilot randomized controlled trial is to examine the preliminary effectiveness and feasibility of a virtual reality job interview tool (VR-JIT) in improving job interview performance in adolescents on the autism spectrum. Method The study was implemented in a high school setting. Fourteen adolescents on the autism spectrum were randomly divided into two groups: an experimental group (n = 7) and a services as usual (SAU) control group (n = 7). The intervention group received 10 h of VR-JIT, which includes interviewing with a virtual human and receiving feedback. All participants performed a video-recorded mock job interview at pre-test and post-test, which was rated by blinded assessors to track interview skills. Students filled out questionnaires related to job interviewing anxiety and self-efficacy pre- and post- intervention. Feasibility metrics were recorded as well. Results Repeated Measures ANOVA revealed improved a metric of job interview performance in the experimental group following the intervention compared to the control group, indicated by medium to large effect sizes. However, perceptions of anxiety and self-efficacy did not improve following the intervention. Students reported that the intervention was easy to use and enjoyable. Conclusions The current pilot study indicates preliminary evidence of the VR-JIT’s effectiveness in improving measures of job interview performance in adolescents on the autism spectrum, even though their own perceptions did not improve. Importantly, the VR-JIT intervention was implemented in a school setting, demonstrating feasibility in its adoption as part of curriculum to help improve employment outcomes in transition age youth on the autism spectrum. En ligne : https://doi.org/10.1016/j.rasd.2021.101878 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458 [article] A pilot RCT of virtual reality job interview training in transition-age youth on the autism spectrum [texte imprimé] / Helen M. GENOVA, Auteur ; Katie LANCASTER, Auteur ; James MORECRAFT, Auteur ; Mikayla HAAS, Auteur ; Alexandra EDWARDS, Auteur ; Michael DIBENEDETTO, Auteur ; Denise KRCH, Auteur ; John DELUCA, Auteur ; Matthew J. SMITH, Auteur . - 101878. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 89 (November 2021) . - 101878 Mots-clés : Autism  Transition age youth  Adolescents  Job interview  Virtual reality  RCT Index. décimale : PER Périodiques Résumé : Background Adolescents on the autism spectrum may have difficulty obtaining and maintaining employment. One particular obstacle for adolescents on the autism spectrum is the job interview. The purpose of the current pilot randomized controlled trial is to examine the preliminary effectiveness and feasibility of a virtual reality job interview tool (VR-JIT) in improving job interview performance in adolescents on the autism spectrum. Method The study was implemented in a high school setting. Fourteen adolescents on the autism spectrum were randomly divided into two groups: an experimental group (n = 7) and a services as usual (SAU) control group (n = 7). The intervention group received 10 h of VR-JIT, which includes interviewing with a virtual human and receiving feedback. All participants performed a video-recorded mock job interview at pre-test and post-test, which was rated by blinded assessors to track interview skills. Students filled out questionnaires related to job interviewing anxiety and self-efficacy pre- and post- intervention. Feasibility metrics were recorded as well. Results Repeated Measures ANOVA revealed improved a metric of job interview performance in the experimental group following the intervention compared to the control group, indicated by medium to large effect sizes. However, perceptions of anxiety and self-efficacy did not improve following the intervention. Students reported that the intervention was easy to use and enjoyable. Conclusions The current pilot study indicates preliminary evidence of the VR-JIT’s effectiveness in improving measures of job interview performance in adolescents on the autism spectrum, even though their own perceptions did not improve. Importantly, the VR-JIT intervention was implemented in a school setting, demonstrating feasibility in its adoption as part of curriculum to help improve employment outcomes in transition age youth on the autism spectrum. En ligne : https://doi.org/10.1016/j.rasd.2021.101878 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458

A Qualitative Study Exploring the Acceptability of Taking Part in a Large Multicentre RCT of Medication for Anxiety in Autistic Adults (the STRATA Trial) / Alba X. REALPE in Autism, 30-9 (September 2026)  

Public ISBD [article]  inAutism > 30-9 (September 2026) . - p.2318-2333 Titre : A Qualitative Study Exploring the Acceptability of Taking Part in a Large Multicentre RCT of Medication for Anxiety in Autistic Adults (the STRATA Trial) Type de document : texte imprimé Auteurs : Alba X. REALPE, Auteur ; Jade Eloise NORRIS, Auteur ; Ava LORENC, Auteur ; Leonora COTTON, Auteur ; Zoe MORGAN, Auteur ; Aws SADIK, Auteur ; Dheeraj RAI, Auteur ; Nicola MILLS, Auteur ; null NULL, Auteur ; David CARMICHAEL, Auteur ; Madeleine COCHRANE, Auteur ; Leonora COTTON, Auteur ; Abbie COTTRELL, Auteur ; Martin HOUSE, Auteur ; David KESSLER, Auteur ; Amanda LEWIS, Auteur ; Ava LORENC, Auteur ; Stephanie MACNEILL, Auteur ; Tim MEDLICOTT, Auteur ; Nicola MILLS, Auteur ; Maximiliano Vazquez MORALES, Auteur ; Jade Eloise NORRIS, Auteur ; Sunita PROCTER, Auteur ; Dheeraj RAI, Auteur ; Alba X REALPE, Auteur ; Jodi TAYLOR, Auteur ; Joanna THORN, Auteur ; Nicholas TURNER, Auteur ; Doug WEBB, Auteur ; Nicola WILES, Auteur ; Sarah DOUGLAS, Auteur ; Peter HALE, Auteur ; Sarah O’BRIEN, Auteur ; Amy WALKER, Auteur ; Jack WELCH, Auteur ; Claire CREE, Auteur ; Liz MCCULLAGH, Auteur ; Alex PARSONS, Auteur ; Jake ALBERTS, Auteur ; Monalisa BORA-WHITE, Auteur ; Alison CAPE, Auteur ; Victoria NIMMO-SMITH, Auteur ; Krist NOONAN, Auteur ; Dheeraj RAI, Auteur ; Aws SADIK, Auteur ; Holly SPRAY, Auteur ; Alexandra YOUNG, Auteur ; Gaurav BHATTARAI, Auteur ; Emma BUTLER, Auteur ; Suzee CHANG, Auteur ; Amy DAVIS, Auteur ; Laura JENKINS, Auteur ; Rose JONES, Auteur ; Laura LORD, Auteur ; Ariska BARBOSA, Auteur ; Didiana DOS SANTOS, Auteur ; Abhishek JHA, Auteur ; Sujata SONI, Auteur ; Kerry FLAHIVE, Auteur ; Emma HORNE, Auteur ; Liz LENAGHAN, Auteur ; Rani PATHANIA, Auteur ; Hafsa SHEIKH, Auteur ; Katie EWART, Auteur ; Anneka NEWMAN, Auteur ; Karen POON, Auteur ; Prasanna RAJBHANDARI, Auteur ; Amy GREEN, Auteur ; Brionne THOMAS, Auteur ; Regi ALEXANDER, Auteur ; Ayomipo Jeremiah AMIOLA, Auteur ; Peter LANGDON, Auteur ; Inder SAWHNEY, Auteur ; Lucy ALLENDER, Auteur ; Wendy ANDRUSJAK, Auteur ; Conor DAVIDSON, Auteur ; Sana FATIMA, Auteur ; Sharmistha GHOSH, Auteur ; Lisa HACKNEY, Auteur ; Alwyn KAM, Auteur ; Keri LODGE, Auteur ; Charlotte MACKNEY-HUDSON, Auteur ; Sarah PARKINSON, Auteur ; Holly LIVESEY, Auteur ; Eleni TSAPPIS, Auteur ; Sharon AUJLA, Auteur ; Sarah BAILLON, Auteur ; Meera BENTLEY, Auteur ; Asit BISWAS, Auteur ; Joy Fellows DAVIS, Auteur ; Ganesh KUNJITHAPATHAM, Auteur ; Rebekah POLE, Auteur ; Samuel TROMANS, Auteur ; Regi ALEXANDER, Auteur ; Catherine HAIG, Auteur ; Stephanie HOWARD, Auteur ; Ayomipo Jeremiah AMIOLA, Auteur ; Charlotte MAPLANKA, Auteur ; Gisela PEREZ-OLIVAS, Auteur ; Jack CHESHIRE, Auteur ; Jacqueline DZIEWANOWSKA, Auteur ; Angela HOLLAND, Auteur ; Puja KOCHHAR, Auteur ; Sowmy MURICKAL, Auteur ; Susan SMITH, Auteur ; Joshua CUDWORTH, Auteur ; Solveig HASELBACH, Auteur ; Jeremy MUDUNKOTUWE, Auteur ; Raja MUKHERJEE, Auteur ; Maria DEL PICCOLO, Auteur ; Ashkan SOWHANI, Auteur ; Emma GLASSON, Auteur ; Katherine HATCH, Auteur ; Helen LEONARD, Auteur ; Sergio STARKSTEIN, Auteur ; Bradleigh HAYHOW, Auteur ; Eleanor TEO, Auteur ; Don HULME, Auteur ; Katrina ORR, Auteur ; Ailsa RUSSELL, Auteur ; Traolach BRUGHA, Auteur ; Zoe MORGAN, Auteur ; David BALDWIN, Auteur ; Peter LANGDON, Auteur ; Jemma REGAN, Auteur ; Jonathan MARTIN, Auteur ; Alice MADDEN, Auteur ; Kathryn JANES, Auteur Article en page(s) : p.2318-2333 Langues : Anglais (eng) Mots-clés : autism  anxiety  randomisation  blinding  RCT  neurodevelopmental conditions  research participation  underserved populations  trial methodology  qualitative research Index. décimale : PER Périodiques Résumé : Autistic adults experience significant physical and mental health inequities yet remain underrepresented in clinical research, with few randomised controlled trials to guide care. Randomised controlled trials (RCTs) of selective serotonin reuptake inhibitors (SSRIs) are limited, underpowered, and rarely focused on anxiety. Anticipating recruitment challenges in a large RCT (“STRATA”) evaluating sertraline for anxiety in autistic adults, we embedded qualitative research to support recruitment, retention, and monitoring trial acceptability. We organised our findings into the theoretical framework of acceptability (TFA) constructs to assess the acceptability of trial design and delivery for autistic adults. We conducted 64 interviews with autistic adults at different trial stages. Data were analysed thematically and mapped to the seven TFA constructs. Participants considered involvement in a blinded medication RCT acceptable across the TFA domains, which they weighed differently when reflecting on anticipated versus experienced aspects of participation. STRATA was a low-burden, ethically sound, and methodologically coherent study for most participants, who reported minimal trade-offs, potential benefits, and self-efficacy in managing anxiety and research participation. Acceptability of trial participation is dynamic and multidimensional, which can be enhanced by meaningful involvement of autistic people throughout the research cycle, accessible participant information design, and responsive ongoing engagement.Lay Abstract Autistic adults often experience poorer physical and mental health than the general population. Yet they are rarely included in clinical research. There have been very few high-quality studies (RCTs) testing medications for anxiety in this group. Most existing studies are small and focus on other outcomes. They don’t provide clear guidance for care. To help address this gap, the STRATA trial tested whether the medication sertraline (an SSRI) can reduce anxiety in autistic adults. Recruiting participants for such trials can be challenging. We included a qualitative study to better understand what helps or hinders people from joining and staying in the trial. We aimed to explore what aspects of the STRATA trial made it easier or more appealing for autistic adults to take part. We used a framework called the theoretical framework of acceptability (TFA) to define acceptability in this context. We interviewed 64 autistic adults at different stages of the trial, including 2 who chose not to take part. Most participants found the trial acceptable when assessed against the seven aspects of the TFA (i.e., how someone feels about taking part, how much effort is needed, whether taking part fits with a person’s values, how well someone understands the study, what someone may have to give up, whether the study is likely to help, and how confident someone feels about taking part). In summary, they felt positive about taking part. They thought the study was ethical and easy to understand and believed it could benefit them. Many also felt more confident in managing their anxiety and contributing to research. STRATA is one of the largest studies of its kind; 318 autistic adults took part across the United Kingdom and Australia. The trial had a very high retention rate. Ninety-two per cent of participants stayed until the main outcome point, and 87% completed the full 52 weeks. How acceptable clinical trials like STRATA are may change during their course, and researchers need to be responsive. To do this well, researchers should involve autistic people meaningfully throughout the research process and from an early stage. Researchers also need to respect individual communication needs and provide clear and accessible information. These approaches were central to STRATA and supported by other studies. En ligne : https://dx.doi.org/10.1177/13623613261466306 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=592 [article] A Qualitative Study Exploring the Acceptability of Taking Part in a Large Multicentre RCT of Medication for Anxiety in Autistic Adults (the STRATA Trial) [texte imprimé] / Alba X. REALPE, Auteur ; Jade Eloise NORRIS, Auteur ; Ava LORENC, Auteur ; Leonora COTTON, Auteur ; Zoe MORGAN, Auteur ; Aws SADIK, Auteur ; Dheeraj RAI, Auteur ; Nicola MILLS, Auteur ; null NULL, Auteur ; David CARMICHAEL, Auteur ; Madeleine COCHRANE, Auteur ; Leonora COTTON, Auteur ; Abbie COTTRELL, Auteur ; Martin HOUSE, Auteur ; David KESSLER, Auteur ; Amanda LEWIS, Auteur ; Ava LORENC, Auteur ; Stephanie MACNEILL, Auteur ; Tim MEDLICOTT, Auteur ; Nicola MILLS, Auteur ; Maximiliano Vazquez MORALES, Auteur ; Jade Eloise NORRIS, Auteur ; Sunita PROCTER, Auteur ; Dheeraj RAI, Auteur ; Alba X REALPE, Auteur ; Jodi TAYLOR, Auteur ; Joanna THORN, Auteur ; Nicholas TURNER, Auteur ; Doug WEBB, Auteur ; Nicola WILES, Auteur ; Sarah DOUGLAS, Auteur ; Peter HALE, Auteur ; Sarah O’BRIEN, Auteur ; Amy WALKER, Auteur ; Jack WELCH, Auteur ; Claire CREE, Auteur ; Liz MCCULLAGH, Auteur ; Alex PARSONS, Auteur ; Jake ALBERTS, Auteur ; Monalisa BORA-WHITE, Auteur ; Alison CAPE, Auteur ; Victoria NIMMO-SMITH, Auteur ; Krist NOONAN, Auteur ; Dheeraj RAI, Auteur ; Aws SADIK, Auteur ; Holly SPRAY, Auteur ; Alexandra YOUNG, Auteur ; Gaurav BHATTARAI, Auteur ; Emma BUTLER, Auteur ; Suzee CHANG, Auteur ; Amy DAVIS, Auteur ; Laura JENKINS, Auteur ; Rose JONES, Auteur ; Laura LORD, Auteur ; Ariska BARBOSA, Auteur ; Didiana DOS SANTOS, Auteur ; Abhishek JHA, Auteur ; Sujata SONI, Auteur ; Kerry FLAHIVE, Auteur ; Emma HORNE, Auteur ; Liz LENAGHAN, Auteur ; Rani PATHANIA, Auteur ; Hafsa SHEIKH, Auteur ; Katie EWART, Auteur ; Anneka NEWMAN, Auteur ; Karen POON, Auteur ; Prasanna RAJBHANDARI, Auteur ; Amy GREEN, Auteur ; Brionne THOMAS, Auteur ; Regi ALEXANDER, Auteur ; Ayomipo Jeremiah AMIOLA, Auteur ; Peter LANGDON, Auteur ; Inder SAWHNEY, Auteur ; Lucy ALLENDER, Auteur ; Wendy ANDRUSJAK, Auteur ; Conor DAVIDSON, Auteur ; Sana FATIMA, Auteur ; Sharmistha GHOSH, Auteur ; Lisa HACKNEY, Auteur ; Alwyn KAM, Auteur ; Keri LODGE, Auteur ; Charlotte MACKNEY-HUDSON, Auteur ; Sarah PARKINSON, Auteur ; Holly LIVESEY, Auteur ; Eleni TSAPPIS, Auteur ; Sharon AUJLA, Auteur ; Sarah BAILLON, Auteur ; Meera BENTLEY, Auteur ; Asit BISWAS, Auteur ; Joy Fellows DAVIS, Auteur ; Ganesh KUNJITHAPATHAM, Auteur ; Rebekah POLE, Auteur ; Samuel TROMANS, Auteur ; Regi ALEXANDER, Auteur ; Catherine HAIG, Auteur ; Stephanie HOWARD, Auteur ; Ayomipo Jeremiah AMIOLA, Auteur ; Charlotte MAPLANKA, Auteur ; Gisela PEREZ-OLIVAS, Auteur ; Jack CHESHIRE, Auteur ; Jacqueline DZIEWANOWSKA, Auteur ; Angela HOLLAND, Auteur ; Puja KOCHHAR, Auteur ; Sowmy MURICKAL, Auteur ; Susan SMITH, Auteur ; Joshua CUDWORTH, Auteur ; Solveig HASELBACH, Auteur ; Jeremy MUDUNKOTUWE, Auteur ; Raja MUKHERJEE, Auteur ; Maria DEL PICCOLO, Auteur ; Ashkan SOWHANI, Auteur ; Emma GLASSON, Auteur ; Katherine HATCH, Auteur ; Helen LEONARD, Auteur ; Sergio STARKSTEIN, Auteur ; Bradleigh HAYHOW, Auteur ; Eleanor TEO, Auteur ; Don HULME, Auteur ; Katrina ORR, Auteur ; Ailsa RUSSELL, Auteur ; Traolach BRUGHA, Auteur ; Zoe MORGAN, Auteur ; David BALDWIN, Auteur ; Peter LANGDON, Auteur ; Jemma REGAN, Auteur ; Jonathan MARTIN, Auteur ; Alice MADDEN, Auteur ; Kathryn JANES, Auteur . - p.2318-2333. Langues : Anglais (eng) in Autism > 30-9 (September 2026) . - p.2318-2333 Mots-clés : autism  anxiety  randomisation  blinding  RCT  neurodevelopmental conditions  research participation  underserved populations  trial methodology  qualitative research Index. décimale : PER Périodiques Résumé : Autistic adults experience significant physical and mental health inequities yet remain underrepresented in clinical research, with few randomised controlled trials to guide care. Randomised controlled trials (RCTs) of selective serotonin reuptake inhibitors (SSRIs) are limited, underpowered, and rarely focused on anxiety. Anticipating recruitment challenges in a large RCT (“STRATA”) evaluating sertraline for anxiety in autistic adults, we embedded qualitative research to support recruitment, retention, and monitoring trial acceptability. We organised our findings into the theoretical framework of acceptability (TFA) constructs to assess the acceptability of trial design and delivery for autistic adults. We conducted 64 interviews with autistic adults at different trial stages. Data were analysed thematically and mapped to the seven TFA constructs. Participants considered involvement in a blinded medication RCT acceptable across the TFA domains, which they weighed differently when reflecting on anticipated versus experienced aspects of participation. STRATA was a low-burden, ethically sound, and methodologically coherent study for most participants, who reported minimal trade-offs, potential benefits, and self-efficacy in managing anxiety and research participation. Acceptability of trial participation is dynamic and multidimensional, which can be enhanced by meaningful involvement of autistic people throughout the research cycle, accessible participant information design, and responsive ongoing engagement.Lay Abstract Autistic adults often experience poorer physical and mental health than the general population. Yet they are rarely included in clinical research. There have been very few high-quality studies (RCTs) testing medications for anxiety in this group. Most existing studies are small and focus on other outcomes. They don’t provide clear guidance for care. To help address this gap, the STRATA trial tested whether the medication sertraline (an SSRI) can reduce anxiety in autistic adults. Recruiting participants for such trials can be challenging. We included a qualitative study to better understand what helps or hinders people from joining and staying in the trial. We aimed to explore what aspects of the STRATA trial made it easier or more appealing for autistic adults to take part. We used a framework called the theoretical framework of acceptability (TFA) to define acceptability in this context. We interviewed 64 autistic adults at different stages of the trial, including 2 who chose not to take part. Most participants found the trial acceptable when assessed against the seven aspects of the TFA (i.e., how someone feels about taking part, how much effort is needed, whether taking part fits with a person’s values, how well someone understands the study, what someone may have to give up, whether the study is likely to help, and how confident someone feels about taking part). In summary, they felt positive about taking part. They thought the study was ethical and easy to understand and believed it could benefit them. Many also felt more confident in managing their anxiety and contributing to research. STRATA is one of the largest studies of its kind; 318 autistic adults took part across the United Kingdom and Australia. The trial had a very high retention rate. Ninety-two per cent of participants stayed until the main outcome point, and 87% completed the full 52 weeks. How acceptable clinical trials like STRATA are may change during their course, and researchers need to be responsive. To do this well, researchers should involve autistic people meaningfully throughout the research process and from an early stage. Researchers also need to respect individual communication needs and provide clear and accessible information. These approaches were central to STRATA and supported by other studies. En ligne : https://dx.doi.org/10.1177/13623613261466306 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=592

Spoken language outcomes in limited language preschoolers with autism and global developmental delay: RCT of early intervention approaches / Connie KASARI in Autism Research, 16-6 (June 2023)  

Public ISBD [article]  inAutism Research > 16-6 (June 2023) . - p.1236-1246 Titre : Spoken language outcomes in limited language preschoolers with autism and global developmental delay: RCT of early intervention approaches Type de document : texte imprimé Auteurs : Connie KASARI, Auteur ; Stephanie SHIRE, Auteur ; Wendy SHIH, Auteur ; Rebecca LANDA, Auteur ; Lynne LEVATO, Auteur ; Tristram SMITH, Auteur Article en page(s) : p.1236-1246 Langues : Anglais (eng) Mots-clés : developmental delay  DTT  JASPER  language  minimally verbal  preschoolers  RCT Index. décimale : PER Périodiques Résumé : Abstract Preschool autistic children with significant global developmental delays and very limited language skills are at high risk for remaining minimally verbal at entry into primary school. This study compared two early intervention models for improving social communication and spoken language outcomes in 164 children who received intervention in their community preschool program for 6 months, with a six-month follow-up. The primary outcome measure was a standardized language assessment, and secondary measures focused on social communication. Results indicated children on average made 6 months gain in language development in the active 6 months of intervention with no difference between intervention models. Children who initiated joint attention more frequently, or who had higher receptive language at baseline made more progress if assigned to receive JASPER, a naturalistic developmental behavioral intervention. Children who received Discrete Trial Training made greater spoken language progress from exit to follow-up. These findings suggest that progress can be made in autistic children who have very little spoken language and who receive targeted early interventions. Individual trajectories vary and depend in part on initial abilities in social communication and receptive language. Future research might consider methods to systematically personalize approaches to fit child characteristics and family preference. Lay Summary This study compared two different early intervention approaches for teaching spoken language to minimally verbal, globally delayed autistic preschoolers. Children were given an hour of therapy daily for 6 months and then reassessed 6 months later. The majority of the 164 participants were from historically excluded populations (low income and minority), and therapy was delivered in school community settings by expert clinicians. Results indicated that the participants made significant progress regardless of intervention approach: 6 months gain in standardized language scores over 6 months, but slower progress during the period after therapy ended. Children who initiated joint attention more frequently, or who had higher language understanding at baseline made more progress if assigned to receive JASPER, a naturalistic developmental behavioral intervention. Children who received Discrete Trial Training made greater language progress during 6-month period after therapy ended. These findings suggest that progress can be made in children with ASD who have very little spoken language and who receive targeted early interventions. En ligne : https://doi.org/10.1002/aur.2932 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=507 [article] Spoken language outcomes in limited language preschoolers with autism and global developmental delay: RCT of early intervention approaches [texte imprimé] / Connie KASARI, Auteur ; Stephanie SHIRE, Auteur ; Wendy SHIH, Auteur ; Rebecca LANDA, Auteur ; Lynne LEVATO, Auteur ; Tristram SMITH, Auteur . - p.1236-1246. Langues : Anglais (eng) in Autism Research > 16-6 (June 2023) . - p.1236-1246 Mots-clés : developmental delay  DTT  JASPER  language  minimally verbal  preschoolers  RCT Index. décimale : PER Périodiques Résumé : Abstract Preschool autistic children with significant global developmental delays and very limited language skills are at high risk for remaining minimally verbal at entry into primary school. This study compared two early intervention models for improving social communication and spoken language outcomes in 164 children who received intervention in their community preschool program for 6 months, with a six-month follow-up. The primary outcome measure was a standardized language assessment, and secondary measures focused on social communication. Results indicated children on average made 6 months gain in language development in the active 6 months of intervention with no difference between intervention models. Children who initiated joint attention more frequently, or who had higher receptive language at baseline made more progress if assigned to receive JASPER, a naturalistic developmental behavioral intervention. Children who received Discrete Trial Training made greater spoken language progress from exit to follow-up. These findings suggest that progress can be made in autistic children who have very little spoken language and who receive targeted early interventions. Individual trajectories vary and depend in part on initial abilities in social communication and receptive language. Future research might consider methods to systematically personalize approaches to fit child characteristics and family preference. Lay Summary This study compared two different early intervention approaches for teaching spoken language to minimally verbal, globally delayed autistic preschoolers. Children were given an hour of therapy daily for 6 months and then reassessed 6 months later. The majority of the 164 participants were from historically excluded populations (low income and minority), and therapy was delivered in school community settings by expert clinicians. Results indicated that the participants made significant progress regardless of intervention approach: 6 months gain in standardized language scores over 6 months, but slower progress during the period after therapy ended. Children who initiated joint attention more frequently, or who had higher language understanding at baseline made more progress if assigned to receive JASPER, a naturalistic developmental behavioral intervention. Children who received Discrete Trial Training made greater language progress during 6-month period after therapy ended. These findings suggest that progress can be made in children with ASD who have very little spoken language and who receive targeted early interventions. En ligne : https://doi.org/10.1002/aur.2932 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=507

Early language screening and intervention can be delivered successfully at scale: evidence from a cluster randomized controlled trial / Gillian WEST in Journal of Child Psychology and Psychiatry, 62-12 (December 2021)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 62-12 (December 2021) . - p.1425-1434 Titre : Early language screening and intervention can be delivered successfully at scale: evidence from a cluster randomized controlled trial Type de document : texte imprimé Auteurs : Gillian WEST, Auteur ; Margaret J. SNOWLING, Auteur ; A. LERVAG, Auteur ; Elizabeth BUCHANAN-WORSTER, Auteur ; Mihaela DUTA, Auteur ; Alexandra HALL, Auteur ; Henrietta MCLACHLAN, Auteur ; Charles HULME, Auteur Article en page(s) : p.1425-1434 Langues : Anglais (eng) Mots-clés : Child  Early Intervention, Educational  Humans  Language  Language Development Disorders  Language Tests  Schools  Rct  education Index. décimale : PER Périodiques Résumé : BACKGROUND: It is well established that oral language skills provide a critical foundation for formal education. This study evaluated the effectiveness of the Nuffield Early Language Intervention (NELI) programme in ameliorating language difficulties in the first year of school when delivered at scale. METHODS: We conducted a cluster randomized controlled trial (RCT) in 193 primary schools (containing 238 Reception classrooms). Schools were randomly allocated to either a 20-week oral language intervention or a business-as-usual control group. All classes (N = 5,879 children) in participating schools were screened by school staff using an automated App to assess children's oral language skills. Screening identified 1,173 children as eligible for language intervention: schools containing 571 of these children were allocated to the control group and 569 to the intervention group. RESULTS: Children receiving the NELI programme made significantly larger gains than the business-as-usual control group on a latent variable reflecting standardized measures of language ability (d = .26) and on the school-administered automated assessment of receptive and expressive language skills (d = .32). The effects of intervention did not vary as a function of home language background or gender. CONCLUSIONS: This study provides strong evidence for the effectiveness of a school-based language intervention programme (NELI) delivered at scale. These findings demonstrate that language difficulties can be identified by school-based testing and ameliorated by a TA delivered intervention; this has important implications for educational and social policy. En ligne : http://dx.doi.org/10.1111/jcpp.13415 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 [article] Early language screening and intervention can be delivered successfully at scale: evidence from a cluster randomized controlled trial [texte imprimé] / Gillian WEST, Auteur ; Margaret J. SNOWLING, Auteur ; A. LERVAG, Auteur ; Elizabeth BUCHANAN-WORSTER, Auteur ; Mihaela DUTA, Auteur ; Alexandra HALL, Auteur ; Henrietta MCLACHLAN, Auteur ; Charles HULME, Auteur . - p.1425-1434. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 62-12 (December 2021) . - p.1425-1434 Mots-clés : Child  Early Intervention, Educational  Humans  Language  Language Development Disorders  Language Tests  Schools  Rct  education Index. décimale : PER Périodiques Résumé : BACKGROUND: It is well established that oral language skills provide a critical foundation for formal education. This study evaluated the effectiveness of the Nuffield Early Language Intervention (NELI) programme in ameliorating language difficulties in the first year of school when delivered at scale. METHODS: We conducted a cluster randomized controlled trial (RCT) in 193 primary schools (containing 238 Reception classrooms). Schools were randomly allocated to either a 20-week oral language intervention or a business-as-usual control group. All classes (N = 5,879 children) in participating schools were screened by school staff using an automated App to assess children's oral language skills. Screening identified 1,173 children as eligible for language intervention: schools containing 571 of these children were allocated to the control group and 569 to the intervention group. RESULTS: Children receiving the NELI programme made significantly larger gains than the business-as-usual control group on a latent variable reflecting standardized measures of language ability (d = .26) and on the school-administered automated assessment of receptive and expressive language skills (d = .32). The effects of intervention did not vary as a function of home language background or gender. CONCLUSIONS: This study provides strong evidence for the effectiveness of a school-based language intervention programme (NELI) delivered at scale. These findings demonstrate that language difficulties can be identified by school-based testing and ameliorated by a TA delivered intervention; this has important implications for educational and social policy. En ligne : http://dx.doi.org/10.1111/jcpp.13415 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456

Parent-mediated intervention in infants with an elevated likelihood for autism reduces dwell time during a gaze-following task / Rachael BEDFORD in Autism Research, 17-11 (November 2024)  

Public ISBD [article]  inAutism Research > 17-11 (November 2024) . - p.2346-2354 Titre : Parent-mediated intervention in infants with an elevated likelihood for autism reduces dwell time during a gaze-following task Type de document : texte imprimé Auteurs : Rachael BEDFORD, Auteur ; Jonathan GREEN, Auteur ; Teodora GLIGA, Auteur ; Emily H. JONES, Auteur ; Mayada ELSABBAGH, Auteur ; Greg PASCO, Auteur ; Ming Wai WAN, Auteur ; Vicky SLONIMS, Auteur ; Tony CHARMAN, Auteur ; Andrew PICKLES, Auteur ; Mark H. JOHNSON, Auteur ; THE BASIS TEAM, Auteur Article en page(s) : p.2346-2354 Langues : Anglais (eng) Mots-clés : autism  elevated likelihood for autism  gaze following  infant siblings  intervention  parent-mediated intervention  RCT Index. décimale : PER Périodiques Résumé : Abstract Cognitive markers may in theory be more sensitive to the effects of intervention than overt behavioral measures. The current study tests the impact of the Intervention with the British Autism Study of Infant Siblings?Video Interaction for Promoting Positive Parenting (iBASIS-VIPP) on an eye-tracking measure of social attention: dwell time to the referred object in a gaze following task. The original two-site, two-arm, assessor-blinded randomized controlled trial (RCT) of this intervention to increase parental awareness, and responsiveness to their infant, was run with infants who have an elevated familial likelihood for autism (EL). Fifty-four EL infants (28 iBASIS-VIPP intervention, 26 no intervention) were enrolled, and the intervention took place between 9 months (baseline) and 15 months (endpoint), with gaze following behavior measured at 15 months. Secondary intention to treat (ITT) analysis showed that the intervention was associated with significantly reduced dwell time to the referent of another person's gaze (? 0.32, SE 0.14, p 0.03) at 15-month treatment endpoint. Given the established link between gaze following and language, the results are considered in the context of a previously reported, non-significant and transient trend toward lower language scores at the treatment endpoint (Green et al. (2015) The Lancet Psychiatry, 2(2), 133 140). Future intervention trials should aim to include experimental cognitive measures, alongside behavioral measures, to investigate mechanisms associated with intervention effects. En ligne : https://doi.org/10.1002/aur.3223 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542 [article] Parent-mediated intervention in infants with an elevated likelihood for autism reduces dwell time during a gaze-following task [texte imprimé] / Rachael BEDFORD, Auteur ; Jonathan GREEN, Auteur ; Teodora GLIGA, Auteur ; Emily H. JONES, Auteur ; Mayada ELSABBAGH, Auteur ; Greg PASCO, Auteur ; Ming Wai WAN, Auteur ; Vicky SLONIMS, Auteur ; Tony CHARMAN, Auteur ; Andrew PICKLES, Auteur ; Mark H. JOHNSON, Auteur ; THE BASIS TEAM, Auteur . - p.2346-2354. Langues : Anglais (eng) in Autism Research > 17-11 (November 2024) . - p.2346-2354 Mots-clés : autism  elevated likelihood for autism  gaze following  infant siblings  intervention  parent-mediated intervention  RCT Index. décimale : PER Périodiques Résumé : Abstract Cognitive markers may in theory be more sensitive to the effects of intervention than overt behavioral measures. The current study tests the impact of the Intervention with the British Autism Study of Infant Siblings?Video Interaction for Promoting Positive Parenting (iBASIS-VIPP) on an eye-tracking measure of social attention: dwell time to the referred object in a gaze following task. The original two-site, two-arm, assessor-blinded randomized controlled trial (RCT) of this intervention to increase parental awareness, and responsiveness to their infant, was run with infants who have an elevated familial likelihood for autism (EL). Fifty-four EL infants (28 iBASIS-VIPP intervention, 26 no intervention) were enrolled, and the intervention took place between 9 months (baseline) and 15 months (endpoint), with gaze following behavior measured at 15 months. Secondary intention to treat (ITT) analysis showed that the intervention was associated with significantly reduced dwell time to the referent of another person's gaze (? 0.32, SE 0.14, p 0.03) at 15-month treatment endpoint. Given the established link between gaze following and language, the results are considered in the context of a previously reported, non-significant and transient trend toward lower language scores at the treatment endpoint (Green et al. (2015) The Lancet Psychiatry, 2(2), 133 140). Future intervention trials should aim to include experimental cognitive measures, alongside behavioral measures, to investigate mechanisms associated with intervention effects. En ligne : https://doi.org/10.1002/aur.3223 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542

A Pilot Randomised Control Trial of Digitally-Mediated Social Stories for Children on the Autism Spectrum / R. HANRAHAN in Journal of Autism and Developmental Disorders, 50-12 (December 2020)  

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A randomized controlled trial into the effects of neurofeedback, methylphenidate, and physical activity on EEG power spectra in children with ADHD / Tieme W.P. JANSSEN in Journal of Child Psychology and Psychiatry, 57-5 (May 2016)  

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A Randomized Waitlist-Control Group Study of a Culturally Tailored Parent Education Intervention for Latino Parents of Children with ASD / Sandy MAGAÑA in Journal of Autism and Developmental Disorders, 50-1 (January 2020)  

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An experimental test of differential susceptibility to parenting among emotionally-dysregulated children in a randomized controlled trial for oppositional behavior / Stephen SCOTT in Journal of Child Psychology and Psychiatry, 53-11 (November 2012)  

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Effects of parent–child interaction therapy dosage on child and parent outcomes: differentiating child-directed interaction and parent-directed interaction session impacts in child welfare-involved families / Xiaolan LIAO in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

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