Adaptation of the “ten questions” to screen for autism and other neurodevelopmental disorders in Uganda / Angelina KAKOOZA-MWESIGE in Autism, 18-4 (May 2014)  

Public ISBD [article]  inAutism > 18-4 (May 2014) . - p.447-457 Titre : Adaptation of the “ten questions” to screen for autism and other neurodevelopmental disorders in Uganda Type de document : Texte imprimé et/ou numérique Auteurs : Angelina KAKOOZA-MWESIGE, Auteur ; Keron SSEBYALA, Auteur ; Charles KARAMAGI, Auteur ; Sarah KIGULI, Auteur ; Karen SMITH, Auteur ; Meredith C. ANDERSON, Auteur ; Lisa A. CROEN, Auteur ; Edwin TREVATHAN, Auteur ; Robin HANSEN, Auteur ; Daniel SMITH, Auteur ; Judith K. GRETHER, Auteur Article en page(s) : p.447-457 Langues : Anglais (eng) Mots-clés : autism spectrum disorder screening and assessment  developing countries  low- and middle-income countries  neurodevelopmental disorder screening and assessment  Uganda Index. décimale : PER Périodiques Résumé : Neurodevelopmental disorders are recognized to be relatively common in developing countries but little data exist for planning effective prevention and intervention strategies. In particular, data on autism spectrum disorders are lacking. For application in Uganda, we developed a 23-question screener (23Q) that includes the Ten Questions screener and additional questions on autism spectrum disorder behaviors. We then conducted household screening of 1169 children, 2–9 years of age, followed by clinical assessment of children who screened positive and a sample of those who screened negative to evaluate the validity of the screener. We found that 320 children (27% of the total) screened positive and 68 children received a clinical diagnosis of one or more moderate to severe neurodevelopmental disorders (autism spectrum disorder; cerebral palsy; epilepsy; cognitive, speech and language, hearing, or vision impairment), including 8 children with autism spectrum disorders. Prevalence and validity of the screener were evaluated under different statistical assumptions. Sensitivity of the 23Q ranged from 0.55 to 0.80 and prevalence for ?1 neurodevelopmental disorders from 7.7/100 children to 12.8/100 children depending on which assumptions were used. The combination of screening positive on both autism spectrum disorders and Ten Questions items was modestly successful in identifying a subgroup of children at especially high risk of autism spectrum disorders. We recommend that autism spectrum disorders and related behavioral disorders be included in studies of neurodevelopmental disorders in low-resource settings to obtain essential data for planning local and global public health responses. En ligne : http://dx.doi.org/10.1177/1362361313475848 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=232 [article] Adaptation of the “ten questions” to screen for autism and other neurodevelopmental disorders in Uganda [Texte imprimé et/ou numérique] / Angelina KAKOOZA-MWESIGE, Auteur ; Keron SSEBYALA, Auteur ; Charles KARAMAGI, Auteur ; Sarah KIGULI, Auteur ; Karen SMITH, Auteur ; Meredith C. ANDERSON, Auteur ; Lisa A. CROEN, Auteur ; Edwin TREVATHAN, Auteur ; Robin HANSEN, Auteur ; Daniel SMITH, Auteur ; Judith K. GRETHER, Auteur . - p.447-457. Langues : Anglais (eng) in Autism > 18-4 (May 2014) . - p.447-457 Mots-clés : autism spectrum disorder screening and assessment  developing countries  low- and middle-income countries  neurodevelopmental disorder screening and assessment  Uganda Index. décimale : PER Périodiques Résumé : Neurodevelopmental disorders are recognized to be relatively common in developing countries but little data exist for planning effective prevention and intervention strategies. In particular, data on autism spectrum disorders are lacking. For application in Uganda, we developed a 23-question screener (23Q) that includes the Ten Questions screener and additional questions on autism spectrum disorder behaviors. We then conducted household screening of 1169 children, 2–9 years of age, followed by clinical assessment of children who screened positive and a sample of those who screened negative to evaluate the validity of the screener. We found that 320 children (27% of the total) screened positive and 68 children received a clinical diagnosis of one or more moderate to severe neurodevelopmental disorders (autism spectrum disorder; cerebral palsy; epilepsy; cognitive, speech and language, hearing, or vision impairment), including 8 children with autism spectrum disorders. Prevalence and validity of the screener were evaluated under different statistical assumptions. Sensitivity of the 23Q ranged from 0.55 to 0.80 and prevalence for ?1 neurodevelopmental disorders from 7.7/100 children to 12.8/100 children depending on which assumptions were used. The combination of screening positive on both autism spectrum disorders and Ten Questions items was modestly successful in identifying a subgroup of children at especially high risk of autism spectrum disorders. We recommend that autism spectrum disorders and related behavioral disorders be included in studies of neurodevelopmental disorders in low-resource settings to obtain essential data for planning local and global public health responses. En ligne : http://dx.doi.org/10.1177/1362361313475848 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=232

Head Circumferences in Twins With and Without Autism Spectrum Disorders / Wendy FROEHLICH in Journal of Autism and Developmental Disorders, 43-9 (September 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-9 (September 2013) . - p.2026-2037 Titre : Head Circumferences in Twins With and Without Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Wendy FROEHLICH, Auteur ; Sue C. CLEVELAND, Auteur ; Andrea TORRES, Auteur ; Jennifer PHILLIPS, Auteur ; Brianne COHEN, Auteur ; Tiffany TORIGOE, Auteur ; Janet MILLER, Auteur ; Angie FEDELE, Auteur ; Jack COLLINS, Auteur ; Karen SMITH, Auteur ; Linda J. LOTSPEICH, Auteur ; Lisa A. CROEN, Auteur ; Sally OZONOFF, Auteur ; Clara LAJONCHERE, Auteur ; Judith K. GRETHER, Auteur ; Joachim F. HALLMAYER, Auteur Article en page(s) : p.2026-2037 Langues : Anglais (eng) Mots-clés : Macrocephaly  Head circumference  Twins  Endophenotype  Genetics Index. décimale : PER Périodiques Résumé : To determine the genetic relationship between head circumference (HC) and Autism Spectrum Disorders (ASDs). Twin pairs with at least one twin with an ASD were assessed. HCs in affected and unaffected individuals were compared, as were HC correlations in monozygotic and dizygotic pairs. 404 subjects, ages 4–18, were included. 20 % of males and 27 % of females with an ASD had macrocephaly. Unaffected co-twins showed similar rates (16 % of males and 22 % of females). Statistical analysis revealed no significant difference in HCs between affected and unaffected twins. Twins with ASDs and unaffected co-twins have similar HCs and increased rates of macrocephaly. Correlations demonstrated partial inheritance of HCs. Thus, macrocephaly may represent an endophenotype in ASDs. En ligne : http://dx.doi.org/10.1007/s10803-012-1751-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=212 [article] Head Circumferences in Twins With and Without Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Wendy FROEHLICH, Auteur ; Sue C. CLEVELAND, Auteur ; Andrea TORRES, Auteur ; Jennifer PHILLIPS, Auteur ; Brianne COHEN, Auteur ; Tiffany TORIGOE, Auteur ; Janet MILLER, Auteur ; Angie FEDELE, Auteur ; Jack COLLINS, Auteur ; Karen SMITH, Auteur ; Linda J. LOTSPEICH, Auteur ; Lisa A. CROEN, Auteur ; Sally OZONOFF, Auteur ; Clara LAJONCHERE, Auteur ; Judith K. GRETHER, Auteur ; Joachim F. HALLMAYER, Auteur . - p.2026-2037. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-9 (September 2013) . - p.2026-2037 Mots-clés : Macrocephaly  Head circumference  Twins  Endophenotype  Genetics Index. décimale : PER Périodiques Résumé : To determine the genetic relationship between head circumference (HC) and Autism Spectrum Disorders (ASDs). Twin pairs with at least one twin with an ASD were assessed. HCs in affected and unaffected individuals were compared, as were HC correlations in monozygotic and dizygotic pairs. 404 subjects, ages 4–18, were included. 20 % of males and 27 % of females with an ASD had macrocephaly. Unaffected co-twins showed similar rates (16 % of males and 22 % of females). Statistical analysis revealed no significant difference in HCs between affected and unaffected twins. Twins with ASDs and unaffected co-twins have similar HCs and increased rates of macrocephaly. Correlations demonstrated partial inheritance of HCs. Thus, macrocephaly may represent an endophenotype in ASDs. En ligne : http://dx.doi.org/10.1007/s10803-012-1751-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=212

Missed opportunities: An investigation of pathways to autism diagnosis in Australia / Vicki GIBBS in Research in Autism Spectrum Disorders, 57 (January 2019)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 57 (January 2019) . - p.55-62 Titre : Missed opportunities: An investigation of pathways to autism diagnosis in Australia Type de document : Texte imprimé et/ou numérique Auteurs : Vicki GIBBS, Auteur ; Fiona J. ALDRIDGE, Auteur ; Elizabeth SBURLATI, Auteur ; Felicity CHANDLER, Auteur ; Karen SMITH, Auteur ; Lauren CHENG, Auteur Article en page(s) : p.55-62 Langues : Anglais (eng) Mots-clés : Autism  Delay  Diagnosis  Age of diagnosis  Diagnostic “gap” Index. décimale : PER Périodiques Résumé : Background Reliable diagnoses of autism can be made as early as two years of age. Many children in Australia are diagnosed with autism at a later age. Delayed diagnosis can lead to missed opportunities for early intervention. This study aims to investigate the factors associated with age of diagnosis in Australia and to examine where delays are occurring in the diagnostic pathway. Method Family and child characteristics, age of first concern, and outcomes of previous professional consultations were collected and analysed for 215 children undergoing assessment for autism in Sydney, Australia. Results The average age of diagnosis was 5 years. Children with more severe autism, and those with no co-morbid diagnosis were diagnosed at a younger age. Average age of first concern was 23 months, and parents consulted professionals, on average, just over 8 months later. Seventy percent of the children were not identified as having possible autism at this initial consultation. The average gap between first consultation and diagnosis of autism was 2 years, 4 months. Conclusions This study provided further evidence of delayed diagnosis of children in Australia. Those with level 2 or 3 autism, no co-morbid diagnosis and earlier parental first concerns were diagnosed earlier. In general, parents have concerns and take action in a timely manner. Delays in the diagnostic pathway were apparent from the first professional consultation where autism was often not identified. This could be addressed by training professionals about early indicators, milder forms of autism, and differential diagnosis. En ligne : https://doi.org/10.1016/j.rasd.2018.10.007 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=371 [article] Missed opportunities: An investigation of pathways to autism diagnosis in Australia [Texte imprimé et/ou numérique] / Vicki GIBBS, Auteur ; Fiona J. ALDRIDGE, Auteur ; Elizabeth SBURLATI, Auteur ; Felicity CHANDLER, Auteur ; Karen SMITH, Auteur ; Lauren CHENG, Auteur . - p.55-62. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 57 (January 2019) . - p.55-62 Mots-clés : Autism  Delay  Diagnosis  Age of diagnosis  Diagnostic “gap” Index. décimale : PER Périodiques Résumé : Background Reliable diagnoses of autism can be made as early as two years of age. Many children in Australia are diagnosed with autism at a later age. Delayed diagnosis can lead to missed opportunities for early intervention. This study aims to investigate the factors associated with age of diagnosis in Australia and to examine where delays are occurring in the diagnostic pathway. Method Family and child characteristics, age of first concern, and outcomes of previous professional consultations were collected and analysed for 215 children undergoing assessment for autism in Sydney, Australia. Results The average age of diagnosis was 5 years. Children with more severe autism, and those with no co-morbid diagnosis were diagnosed at a younger age. Average age of first concern was 23 months, and parents consulted professionals, on average, just over 8 months later. Seventy percent of the children were not identified as having possible autism at this initial consultation. The average gap between first consultation and diagnosis of autism was 2 years, 4 months. Conclusions This study provided further evidence of delayed diagnosis of children in Australia. Those with level 2 or 3 autism, no co-morbid diagnosis and earlier parental first concerns were diagnosed earlier. In general, parents have concerns and take action in a timely manner. Delays in the diagnostic pathway were apparent from the first professional consultation where autism was often not identified. This could be addressed by training professionals about early indicators, milder forms of autism, and differential diagnosis. En ligne : https://doi.org/10.1016/j.rasd.2018.10.007 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=371

---

1 (1 - 3 / 3)