[article]
| Titre : |
Brainstem White Matter Predicts Individual Differences in Manual Motor Difficulties and Symptom Severity in Autism |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
Brittany G. TRAVERS, Auteur ; Erin D. BIGLER, Auteur ; Do P. M. TROMP, Auteur ; Nagesh ADLURU, Auteur ; Dan DESTICHE, Auteur ; Danica SAMSIN, Auteur ; Alyson FROEHLICH, Auteur ; Molly D. B. PRIGGE, Auteur ; Tyler C. DUFFIELD, Auteur ; Nicholas LANGE, Auteur ; Andrew L. ALEXANDER, Auteur ; Janet E. LAINHART, Auteur |
| Article en page(s) : |
p.3030-3040 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Autism Motor Diffusion tensor imaging Brainstem Grip strength Finger tapping |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Mounting evidence suggests that poorer motor skills may be related to more severe autism symptoms. This study investigated if atypical white matter microstructure in the brain mediated the relationship between motor skills and ASD symptom severity. Sixty-seven males with ASD and 42 males with typical development (5–33 years old) completed a diffusion tensor imaging scan and measures of grip strength, finger tapping, and autism symptom severity. Within the ASD group, weaker grip strength predicted more severe autism symptoms. Fractional anisotropy of the brainstem’s corticospinal tract predicted both grip strength and autism symptom severity and mediated the relationship between the two. These findings suggest that brainstem white matter may contribute to autism symptoms and grip strength in ASD. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-015-2467-9 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=267 |
in Journal of Autism and Developmental Disorders > 45-9 (September 2015) . - p.3030-3040
[article] Brainstem White Matter Predicts Individual Differences in Manual Motor Difficulties and Symptom Severity in Autism [Texte imprimé et/ou numérique] / Brittany G. TRAVERS, Auteur ; Erin D. BIGLER, Auteur ; Do P. M. TROMP, Auteur ; Nagesh ADLURU, Auteur ; Dan DESTICHE, Auteur ; Danica SAMSIN, Auteur ; Alyson FROEHLICH, Auteur ; Molly D. B. PRIGGE, Auteur ; Tyler C. DUFFIELD, Auteur ; Nicholas LANGE, Auteur ; Andrew L. ALEXANDER, Auteur ; Janet E. LAINHART, Auteur . - p.3030-3040. Langues : Anglais ( eng) in Journal of Autism and Developmental Disorders > 45-9 (September 2015) . - p.3030-3040
| Mots-clés : |
Autism Motor Diffusion tensor imaging Brainstem Grip strength Finger tapping |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Mounting evidence suggests that poorer motor skills may be related to more severe autism symptoms. This study investigated if atypical white matter microstructure in the brain mediated the relationship between motor skills and ASD symptom severity. Sixty-seven males with ASD and 42 males with typical development (5–33 years old) completed a diffusion tensor imaging scan and measures of grip strength, finger tapping, and autism symptom severity. Within the ASD group, weaker grip strength predicted more severe autism symptoms. Fractional anisotropy of the brainstem’s corticospinal tract predicted both grip strength and autism symptom severity and mediated the relationship between the two. These findings suggest that brainstem white matter may contribute to autism symptoms and grip strength in ASD. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-015-2467-9 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=267 |
|
Brainstem White Matter Predicts Individual Differences in Manual Motor Difficulties and Symptom Severity in Autism in Journal of Autism and Developmental Disorders, 45-9 (September 2015)
