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Finger tapping-related activation differences in treatment-naïve pediatric Tourette syndrome: a comparison of the preferred and nonpreferred hand / Veit ROESSNER in Journal of Child Psychology and Psychiatry, 54-3 (March 2013)
[article]
Titre : Finger tapping-related activation differences in treatment-naïve pediatric Tourette syndrome: a comparison of the preferred and nonpreferred hand Type de document : Texte imprimé et/ou numérique Auteurs : Veit ROESSNER, Auteur ; Matthias WITTFOTH, Auteur ; Julia M. AUGUST, Auteur ; Aribert ROTHENBERGER, Auteur ; Jürgen BAUDEWIG, Auteur ; Peter DECHENT, Auteur Article en page(s) : p.273-279 Mots-clés : Finger tapping motor network tourette syndrome primary sensorimotor cortex children Index. décimale : PER Périodiques Résumé : Background: Disturbances of motor circuitry are commonly encountered in Tourette syndrome (TS). The aim of this study was to investigate simple motor performance differences between boys with TS and healthy controls. Methods: We attempted to provide insight into motor network alterations by studying a group of treatment-naïve patients suffering from ‘pure’ TS, i.e., without comorbid symptomatology at an early stage of disease. We used functional MRI to compare activation patterns during right (preferred) and left (nonpreferred) index finger tapping between 22 TS boys (12.6 ± 1.7 years) and 22 age-matched healthy control boys. Results: Boys with TS revealed altered motor network recruitment for right (dominant) and left (nondominant) index finger tapping. Brain activation patterns in response to index finger tapping of the nonpreferred left hand reflected the most prominent differences, including activation decrease in contralateral sensorimotor cortex while recruiting premotor and prefrontal regions along with the left inferior parietal lobule to a greater extent. Conclusions: This study demonstrates clear functional differences of simple index finger tapping in early-stage TS. We suggest that this reflects the requirement for additional brain networks to keep a normal performance level during the actual task and adaptive mechanisms due to continuous tic suppression and performance in TS. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2012.02584.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=191
in Journal of Child Psychology and Psychiatry > 54-3 (March 2013) . - p.273-279[article] Finger tapping-related activation differences in treatment-naïve pediatric Tourette syndrome: a comparison of the preferred and nonpreferred hand [Texte imprimé et/ou numérique] / Veit ROESSNER, Auteur ; Matthias WITTFOTH, Auteur ; Julia M. AUGUST, Auteur ; Aribert ROTHENBERGER, Auteur ; Jürgen BAUDEWIG, Auteur ; Peter DECHENT, Auteur . - p.273-279.
in Journal of Child Psychology and Psychiatry > 54-3 (March 2013) . - p.273-279
Mots-clés : Finger tapping motor network tourette syndrome primary sensorimotor cortex children Index. décimale : PER Périodiques Résumé : Background: Disturbances of motor circuitry are commonly encountered in Tourette syndrome (TS). The aim of this study was to investigate simple motor performance differences between boys with TS and healthy controls. Methods: We attempted to provide insight into motor network alterations by studying a group of treatment-naïve patients suffering from ‘pure’ TS, i.e., without comorbid symptomatology at an early stage of disease. We used functional MRI to compare activation patterns during right (preferred) and left (nonpreferred) index finger tapping between 22 TS boys (12.6 ± 1.7 years) and 22 age-matched healthy control boys. Results: Boys with TS revealed altered motor network recruitment for right (dominant) and left (nondominant) index finger tapping. Brain activation patterns in response to index finger tapping of the nonpreferred left hand reflected the most prominent differences, including activation decrease in contralateral sensorimotor cortex while recruiting premotor and prefrontal regions along with the left inferior parietal lobule to a greater extent. Conclusions: This study demonstrates clear functional differences of simple index finger tapping in early-stage TS. We suggest that this reflects the requirement for additional brain networks to keep a normal performance level during the actual task and adaptive mechanisms due to continuous tic suppression and performance in TS. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2012.02584.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=191 Brainstem White Matter Predicts Individual Differences in Manual Motor Difficulties and Symptom Severity in Autism / Brittany G. TRAVERS in Journal of Autism and Developmental Disorders, 45-9 (September 2015)
[article]
Titre : Brainstem White Matter Predicts Individual Differences in Manual Motor Difficulties and Symptom Severity in Autism Type de document : Texte imprimé et/ou numérique Auteurs : Brittany G. TRAVERS, Auteur ; Erin D. BIGLER, Auteur ; Do P. M. TROMP, Auteur ; Nagesh ADLURU, Auteur ; Dan DESTICHE, Auteur ; Danica SAMSIN, Auteur ; Alyson FROEHLICH, Auteur ; Molly D. B. PRIGGE, Auteur ; Tyler C. DUFFIELD, Auteur ; Nicholas LANGE, Auteur ; Andrew L. ALEXANDER, Auteur ; Janet E. LAINHART, Auteur Article en page(s) : p.3030-3040 Langues : Anglais (eng) Mots-clés : Autism Motor Diffusion tensor imaging Brainstem Grip strength Finger tapping Index. décimale : PER Périodiques Résumé : Mounting evidence suggests that poorer motor skills may be related to more severe autism symptoms. This study investigated if atypical white matter microstructure in the brain mediated the relationship between motor skills and ASD symptom severity. Sixty-seven males with ASD and 42 males with typical development (5–33 years old) completed a diffusion tensor imaging scan and measures of grip strength, finger tapping, and autism symptom severity. Within the ASD group, weaker grip strength predicted more severe autism symptoms. Fractional anisotropy of the brainstem’s corticospinal tract predicted both grip strength and autism symptom severity and mediated the relationship between the two. These findings suggest that brainstem white matter may contribute to autism symptoms and grip strength in ASD. En ligne : http://dx.doi.org/10.1007/s10803-015-2467-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=267
in Journal of Autism and Developmental Disorders > 45-9 (September 2015) . - p.3030-3040[article] Brainstem White Matter Predicts Individual Differences in Manual Motor Difficulties and Symptom Severity in Autism [Texte imprimé et/ou numérique] / Brittany G. TRAVERS, Auteur ; Erin D. BIGLER, Auteur ; Do P. M. TROMP, Auteur ; Nagesh ADLURU, Auteur ; Dan DESTICHE, Auteur ; Danica SAMSIN, Auteur ; Alyson FROEHLICH, Auteur ; Molly D. B. PRIGGE, Auteur ; Tyler C. DUFFIELD, Auteur ; Nicholas LANGE, Auteur ; Andrew L. ALEXANDER, Auteur ; Janet E. LAINHART, Auteur . - p.3030-3040.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 45-9 (September 2015) . - p.3030-3040
Mots-clés : Autism Motor Diffusion tensor imaging Brainstem Grip strength Finger tapping Index. décimale : PER Périodiques Résumé : Mounting evidence suggests that poorer motor skills may be related to more severe autism symptoms. This study investigated if atypical white matter microstructure in the brain mediated the relationship between motor skills and ASD symptom severity. Sixty-seven males with ASD and 42 males with typical development (5–33 years old) completed a diffusion tensor imaging scan and measures of grip strength, finger tapping, and autism symptom severity. Within the ASD group, weaker grip strength predicted more severe autism symptoms. Fractional anisotropy of the brainstem’s corticospinal tract predicted both grip strength and autism symptom severity and mediated the relationship between the two. These findings suggest that brainstem white matter may contribute to autism symptoms and grip strength in ASD. En ligne : http://dx.doi.org/10.1007/s10803-015-2467-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=267 Decreased anterior cingulate activation in a motor task in youths with bipolar disorder / J. B. KING in Journal of Child Psychology and Psychiatry, 59-8 (August 2018)
[article]
Titre : Decreased anterior cingulate activation in a motor task in youths with bipolar disorder Type de document : Texte imprimé et/ou numérique Auteurs : J. B. KING, Auteur ; Jeffrey S. ANDERSON, Auteur ; D. A. YURGELUN-TODD, Auteur ; P. SUBRAMANIAM, Auteur ; M. R. EHRLER, Auteur ; M. P. LOPEZ-LARSON, Auteur Article en page(s) : p.900-907 Langues : Anglais (eng) Mots-clés : Bipolar disorder adolescents anterior cingulate fMRI finger tapping Index. décimale : PER Périodiques Résumé : BACKGROUND: Bipolar disorder (BP) is characterized by abnormal shifts in mood between episodes of mania and severe depression, both of which have been linked with psychomotor disturbances. This study compares brain activation patterns in motor networks between euthymic youths with BP and healthy controls (HC) during the completion of a simple motor task. METHODS: Thirty-five youths with BP and 35 HC (aged 10-19) completed a self-paced sequential bilateral finger-tapping task, consisting of a 4-minute scan block with alternating 20-second periods of either the tapping task (six blocks) or rest (six blocks), while undergoing functional magnetic resonance imaging. Clinical and behavioral symptoms were assessed using the Child Behavior Checklist (CBCL). A between-group whole-brain analysis compared activation pattern differences while controlling for effects of age and sex. Clusters meeting whole-brain false discovery rate (FDR) correction (qFDR < .05) were considered statistically significant. Post hoc analyses evaluating comorbid attention-deficit/hyperactivity disorder (ADHD) in the BP group were also conducted. RESULTS: Significantly decreased activation was found in the anterior cingulate cortex (ACC) in youths with BP compared to HC. Furthermore, ACC activation was negatively correlated with CBCL mood dysregulation profile scores in the BP group. No significant differences in functional activation patterns were found between youths with BP and comorbid ADHD and those with only BP. CONCLUSIONS: These findings suggest a potential common mechanism of impaired ACC modulation between emotion dysregulation and motor processing in youths with BP. En ligne : http://dx.doi.org/10.1111/jcpp.12875 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368
in Journal of Child Psychology and Psychiatry > 59-8 (August 2018) . - p.900-907[article] Decreased anterior cingulate activation in a motor task in youths with bipolar disorder [Texte imprimé et/ou numérique] / J. B. KING, Auteur ; Jeffrey S. ANDERSON, Auteur ; D. A. YURGELUN-TODD, Auteur ; P. SUBRAMANIAM, Auteur ; M. R. EHRLER, Auteur ; M. P. LOPEZ-LARSON, Auteur . - p.900-907.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 59-8 (August 2018) . - p.900-907
Mots-clés : Bipolar disorder adolescents anterior cingulate fMRI finger tapping Index. décimale : PER Périodiques Résumé : BACKGROUND: Bipolar disorder (BP) is characterized by abnormal shifts in mood between episodes of mania and severe depression, both of which have been linked with psychomotor disturbances. This study compares brain activation patterns in motor networks between euthymic youths with BP and healthy controls (HC) during the completion of a simple motor task. METHODS: Thirty-five youths with BP and 35 HC (aged 10-19) completed a self-paced sequential bilateral finger-tapping task, consisting of a 4-minute scan block with alternating 20-second periods of either the tapping task (six blocks) or rest (six blocks), while undergoing functional magnetic resonance imaging. Clinical and behavioral symptoms were assessed using the Child Behavior Checklist (CBCL). A between-group whole-brain analysis compared activation pattern differences while controlling for effects of age and sex. Clusters meeting whole-brain false discovery rate (FDR) correction (qFDR < .05) were considered statistically significant. Post hoc analyses evaluating comorbid attention-deficit/hyperactivity disorder (ADHD) in the BP group were also conducted. RESULTS: Significantly decreased activation was found in the anterior cingulate cortex (ACC) in youths with BP compared to HC. Furthermore, ACC activation was negatively correlated with CBCL mood dysregulation profile scores in the BP group. No significant differences in functional activation patterns were found between youths with BP and comorbid ADHD and those with only BP. CONCLUSIONS: These findings suggest a potential common mechanism of impaired ACC modulation between emotion dysregulation and motor processing in youths with BP. En ligne : http://dx.doi.org/10.1111/jcpp.12875 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368