[article]
| Titre : |
Gray Matter Characteristics in Mid and Old Aged Adults with ASD |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
P. Cédric M. P. KOOLSCHIJN, Auteur ; Hilde M. GEURTS, Auteur |
| Article en page(s) : |
p.2666-2678 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Autism Gray matter volume Cortical thickness Surface area Gyrification Adults |
| Index. décimale : |
PER Périodiques |
| Résumé : |
It is widely acknowledged that the brain anatomy of children and adolescents with autism spectrum disorder (ASD) shows a different developmental pattern then typical age-matched peers. There is however, a paucity of studies examining gray matter in mid and late adulthood in ASD. In this cross-sectional neuroimaging study, we, performed vertex-wise whole-brain and region-of-interest analyses of cortical volume, thickness, surface area, and gyrification index in 51 adults with and 49 without ASD, between 30 and 75 years. There was significant age-related volume loss and cortical thinning, but there were no group differences. The lack of significant anatomical differences between intellectual able individuals with and without ASD, suggests that ASD is not (strongly) related to gray matter morphology in mid and late adulthood. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-016-2810-9 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290 |
in Journal of Autism and Developmental Disorders > 46-8 (August 2016) . - p.2666-2678
[article] Gray Matter Characteristics in Mid and Old Aged Adults with ASD [Texte imprimé et/ou numérique] / P. Cédric M. P. KOOLSCHIJN, Auteur ; Hilde M. GEURTS, Auteur . - p.2666-2678. Langues : Anglais ( eng) in Journal of Autism and Developmental Disorders > 46-8 (August 2016) . - p.2666-2678
| Mots-clés : |
Autism Gray matter volume Cortical thickness Surface area Gyrification Adults |
| Index. décimale : |
PER Périodiques |
| Résumé : |
It is widely acknowledged that the brain anatomy of children and adolescents with autism spectrum disorder (ASD) shows a different developmental pattern then typical age-matched peers. There is however, a paucity of studies examining gray matter in mid and late adulthood in ASD. In this cross-sectional neuroimaging study, we, performed vertex-wise whole-brain and region-of-interest analyses of cortical volume, thickness, surface area, and gyrification index in 51 adults with and 49 without ASD, between 30 and 75 years. There was significant age-related volume loss and cortical thinning, but there were no group differences. The lack of significant anatomical differences between intellectual able individuals with and without ASD, suggests that ASD is not (strongly) related to gray matter morphology in mid and late adulthood. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-016-2810-9 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290 |
|
Gray Matter Characteristics in Mid and Old Aged Adults with ASD in Journal of Autism and Developmental Disorders, 46-8 (August 2016)
