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Auteur Hilde M. GEURTS |
Documents disponibles écrits par cet auteur (40)



Age-related differences in cognition across the adult lifespan in autism spectrum disorder / Anne G. LEVER in Autism Research, 9-6 (June 2016)
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Titre : Age-related differences in cognition across the adult lifespan in autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Anne G. LEVER, Auteur ; Hilde M. GEURTS, Auteur Article en page(s) : p.666-676 Langues : Anglais (eng) Mots-clés : autism spectrum disorder aging older adults cognition neuropsychology memory theory of mind generativity Index. décimale : PER Périodiques Résumé : It is largely unknown how age impacts cognition in autism spectrum disorder (ASD). We investigated whether age-related cognitive differences are similar, reduced or increased across the adult lifespan, examined cognitive strengths and weaknesses, and explored whether objective test performance is related to subjective cognitive challenges. Neuropsychological tests assessing visual and verbal memory, generativity, and theory of mind (ToM), and a self-report measure assessing cognitive failures were administered to 236 matched participants with and without ASD, aged 20–79 years (IQ?>?80). Group comparisons revealed that individuals with ASD had higher scores on visual memory, lower scores on generativity and ToM, and similar performance on verbal memory. However, ToM impairments were no longer present in older (50+ years) adults with ASD. Across adulthood, individuals with ASD demonstrated similar age-related effects on verbal memory, generativity, and ToM, while age-related differences were reduced on visual memory. Although adults with ASD reported many cognitive failures, those were not associated with neuropsychological test performance. Hence, while some cognitive abilities (visual and verbal memory) and difficulties (generativity and semantic memory) persist across adulthood in ASD, others become less apparent in old age (ToM). Age-related differences characteristic of typical aging are reduced or parallel, but not increased in individuals with ASD, suggesting that ASD may partially protect against an age-related decrease in cognitive functioning. Despite these findings, adults with ASD experience many cognitive daily challenges, which highlights the need for adequate social support and the importance of further research into this topic, including longitudinal studies. Autism Res 2016, 9: 666–676. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1545 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290
in Autism Research > 9-6 (June 2016) . - p.666-676[article] Age-related differences in cognition across the adult lifespan in autism spectrum disorder [Texte imprimé et/ou numérique] / Anne G. LEVER, Auteur ; Hilde M. GEURTS, Auteur . - p.666-676.
Langues : Anglais (eng)
in Autism Research > 9-6 (June 2016) . - p.666-676
Mots-clés : autism spectrum disorder aging older adults cognition neuropsychology memory theory of mind generativity Index. décimale : PER Périodiques Résumé : It is largely unknown how age impacts cognition in autism spectrum disorder (ASD). We investigated whether age-related cognitive differences are similar, reduced or increased across the adult lifespan, examined cognitive strengths and weaknesses, and explored whether objective test performance is related to subjective cognitive challenges. Neuropsychological tests assessing visual and verbal memory, generativity, and theory of mind (ToM), and a self-report measure assessing cognitive failures were administered to 236 matched participants with and without ASD, aged 20–79 years (IQ?>?80). Group comparisons revealed that individuals with ASD had higher scores on visual memory, lower scores on generativity and ToM, and similar performance on verbal memory. However, ToM impairments were no longer present in older (50+ years) adults with ASD. Across adulthood, individuals with ASD demonstrated similar age-related effects on verbal memory, generativity, and ToM, while age-related differences were reduced on visual memory. Although adults with ASD reported many cognitive failures, those were not associated with neuropsychological test performance. Hence, while some cognitive abilities (visual and verbal memory) and difficulties (generativity and semantic memory) persist across adulthood in ASD, others become less apparent in old age (ToM). Age-related differences characteristic of typical aging are reduced or parallel, but not increased in individuals with ASD, suggesting that ASD may partially protect against an age-related decrease in cognitive functioning. Despite these findings, adults with ASD experience many cognitive daily challenges, which highlights the need for adequate social support and the importance of further research into this topic, including longitudinal studies. Autism Res 2016, 9: 666–676. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1545 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290 Age Related Differences of Executive Functioning Problems in Everyday Life of Children and Adolescents in the Autism Spectrum / Sanne F. W. M. VAN DEN BERGH in Journal of Autism and Developmental Disorders, 44-8 (August 2014)
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Titre : Age Related Differences of Executive Functioning Problems in Everyday Life of Children and Adolescents in the Autism Spectrum Type de document : Texte imprimé et/ou numérique Auteurs : Sanne F. W. M. VAN DEN BERGH, Auteur ; Anke M. SCHEEREN, Auteur ; Sander BEGEER, Auteur ; Hans M. KOOT, Auteur ; Hilde M. GEURTS, Auteur Article en page(s) : p.1959-1971 Langues : Anglais (eng) Mots-clés : ASD Autism severity Behavioral Rating Inventory Executive Functions (BRIEF) Development Executive functioning Index. décimale : PER Périodiques Résumé : Numerous studies investigated executive functioning (EF) problems in people with autism spectrum disorders (ASD) using laboratory EF tasks. As laboratory task performances often differ from real life observations, the current study focused on EF in everyday life of 118 children and adolescents with ASD (6–18 years). We investigated age-related and individual differences in EF problems as reported by parents on the Behavioral Rating Inventory Executive Functions (BRIEF: Gioia et al. in Behavior rating inventory of executive function. Psychological Assessment Resources, Odesse 2000), and examined the association with autism severity. Inhibition problems were mostly found in the youngest group (6- to 8-year-olds), whereas problems with planning where more evident for 12- to 14-year-olds as compared to 9- to 11-year-olds. In a subsample of participants meeting the ADOS ASD cut-off criteria the age related differences in planning were absent, while problems with cognitive flexibility were less apparent in 15- to 18-year-olds, compared to 9- to 11-, and 12- to 14-year olds. EF problems surpassing the clinical cutoff were only observed in 20 % (planning) to 51 % (cognitive flexibility) of the children and adolescents, and no relation was found with ASD symptom severity. This underlines the heterogeneous nature of ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2071-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=236
in Journal of Autism and Developmental Disorders > 44-8 (August 2014) . - p.1959-1971[article] Age Related Differences of Executive Functioning Problems in Everyday Life of Children and Adolescents in the Autism Spectrum [Texte imprimé et/ou numérique] / Sanne F. W. M. VAN DEN BERGH, Auteur ; Anke M. SCHEEREN, Auteur ; Sander BEGEER, Auteur ; Hans M. KOOT, Auteur ; Hilde M. GEURTS, Auteur . - p.1959-1971.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 44-8 (August 2014) . - p.1959-1971
Mots-clés : ASD Autism severity Behavioral Rating Inventory Executive Functions (BRIEF) Development Executive functioning Index. décimale : PER Périodiques Résumé : Numerous studies investigated executive functioning (EF) problems in people with autism spectrum disorders (ASD) using laboratory EF tasks. As laboratory task performances often differ from real life observations, the current study focused on EF in everyday life of 118 children and adolescents with ASD (6–18 years). We investigated age-related and individual differences in EF problems as reported by parents on the Behavioral Rating Inventory Executive Functions (BRIEF: Gioia et al. in Behavior rating inventory of executive function. Psychological Assessment Resources, Odesse 2000), and examined the association with autism severity. Inhibition problems were mostly found in the youngest group (6- to 8-year-olds), whereas problems with planning where more evident for 12- to 14-year-olds as compared to 9- to 11-year-olds. In a subsample of participants meeting the ADOS ASD cut-off criteria the age related differences in planning were absent, while problems with cognitive flexibility were less apparent in 15- to 18-year-olds, compared to 9- to 11-, and 12- to 14-year olds. EF problems surpassing the clinical cutoff were only observed in 20 % (planning) to 51 % (cognitive flexibility) of the children and adolescents, and no relation was found with ASD symptom severity. This underlines the heterogeneous nature of ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2071-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=236 An Explorative Study of Atypical Social Interaction Styles in Adult Men with Autism Spectrum Disorder, Men with Personality Disorders and Men from the General Population / Richard VUIJK ; Pieter de Nijs ; Arnoud ARNTZ ; Hilde M. GEURTS in Journal of Autism and Developmental Disorders, 53-6 (June 2023)
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Titre : An Explorative Study of Atypical Social Interaction Styles in Adult Men with Autism Spectrum Disorder, Men with Personality Disorders and Men from the General Population : Journal of Autism and Developmental Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Richard VUIJK, Auteur ; Pieter de Nijs, Auteur ; Arnoud ARNTZ, Auteur ; Hilde M. GEURTS, Auteur Article en page(s) : p.2297-2305 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Different atypical social interaction styles (SISs) were defined and tested in children and adolescents with autism spectrum disorder (ASD). Whether these styles can also be distinguished in adults with ASD has not yet been explored. In men with ASD, men with personality disorder (PD), and men from the general population (N=90), aged 18-65 years, we tested which SISs can be distinguished and how they relate to the presence of PD traits. We found a significant distinction in allocation to atypical SISs between the three groups. This study shows the presence of atypical SISs in adults with ASD, and complements previous SIS findings in children and adolescents with ASD. En ligne : https://doi.org/10.1007/s10803-022-05521-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=506
in Journal of Autism and Developmental Disorders > 53-6 (June 2023) . - p.2297-2305[article] An Explorative Study of Atypical Social Interaction Styles in Adult Men with Autism Spectrum Disorder, Men with Personality Disorders and Men from the General Population : Journal of Autism and Developmental Disorders [Texte imprimé et/ou numérique] / Richard VUIJK, Auteur ; Pieter de Nijs, Auteur ; Arnoud ARNTZ, Auteur ; Hilde M. GEURTS, Auteur . - p.2297-2305.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 53-6 (June 2023) . - p.2297-2305
Index. décimale : PER Périodiques Résumé : Different atypical social interaction styles (SISs) were defined and tested in children and adolescents with autism spectrum disorder (ASD). Whether these styles can also be distinguished in adults with ASD has not yet been explored. In men with ASD, men with personality disorder (PD), and men from the general population (N=90), aged 18-65 years, we tested which SISs can be distinguished and how they relate to the presence of PD traits. We found a significant distinction in allocation to atypical SISs between the three groups. This study shows the presence of atypical SISs in adults with ASD, and complements previous SIS findings in children and adolescents with ASD. En ligne : https://doi.org/10.1007/s10803-022-05521-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=506 Annual Research Review: Reaction time variability in ADHD and autism spectrum disorders: measurement and mechanisms of a proposed trans-diagnostic phenotype / Sarah L. KARALUNAS in Journal of Child Psychology and Psychiatry, 55-6 (June 2014)
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Titre : Annual Research Review: Reaction time variability in ADHD and autism spectrum disorders: measurement and mechanisms of a proposed trans-diagnostic phenotype Type de document : Texte imprimé et/ou numérique Auteurs : Sarah L. KARALUNAS, Auteur ; Hilde M. GEURTS, Auteur ; Kerstin KONRAD, Auteur ; Stephan BENDER, Auteur ; Joel T. NIGG, Auteur Année de publication : 2014 Article en page(s) : p.685-710 Langues : Anglais (eng) Mots-clés : Reaction time variability intraindividual ADHD ASD trans-diagnostic phenotype biomarker Index. décimale : PER Périodiques Résumé : Background Intraindividual variability in reaction time (RT) has received extensive discussion as an indicator of cognitive performance, a putative intermediate phenotype of many clinical disorders, and a possible trans-diagnostic phenotype that may elucidate shared risk factors for mechanisms of psychiatric illnesses. Scope and Methodology Using the examples of attention deficit hyperactivity disorder (ADHD) and autism spectrum disorders (ASD), we discuss RT variability. We first present a new meta-analysis of RT variability in ASD with and without comorbid ADHD. We then discuss potential mechanisms that may account for RT variability and statistical models that disentangle the cognitive processes affecting RTs. We then report a second meta-analysis comparing ADHD and non-ADHD children on diffusion model parameters. We consider how findings inform the search for neural correlates of RT variability. Findings Results suggest that RT variability is increased in ASD only when children with comorbid ADHD are included in the sample. Furthermore, RT variability in ADHD is explained by moderate to large increases (d = 0.63–0.99) in the ex-Gaussian parameter ? and the diffusion parameter drift rate, as well as by smaller differences (d = 0.32) in the diffusion parameter of nondecision time. The former may suggest problems in state regulation or arousal and difficulty detecting signal from noise, whereas the latter may reflect contributions from deficits in motor organization or output. The neuroimaging literature converges with this multicomponent interpretation and also highlights the role of top-down control circuits. Conclusion We underscore the importance of considering the interactions between top-down control, state regulation (e.g. arousal), and motor preparation when interpreting RT variability and conclude that decomposition of the RT signal provides superior interpretive power and suggests mechanisms convergent with those implicated using other cognitive paradigms. We conclude with specific recommendations for the field for next steps in the study of RT variability in neurodevelopmental disorders. En ligne : http://dx.doi.org/10.1111/jcpp.12217 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=234
in Journal of Child Psychology and Psychiatry > 55-6 (June 2014) . - p.685-710[article] Annual Research Review: Reaction time variability in ADHD and autism spectrum disorders: measurement and mechanisms of a proposed trans-diagnostic phenotype [Texte imprimé et/ou numérique] / Sarah L. KARALUNAS, Auteur ; Hilde M. GEURTS, Auteur ; Kerstin KONRAD, Auteur ; Stephan BENDER, Auteur ; Joel T. NIGG, Auteur . - 2014 . - p.685-710.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 55-6 (June 2014) . - p.685-710
Mots-clés : Reaction time variability intraindividual ADHD ASD trans-diagnostic phenotype biomarker Index. décimale : PER Périodiques Résumé : Background Intraindividual variability in reaction time (RT) has received extensive discussion as an indicator of cognitive performance, a putative intermediate phenotype of many clinical disorders, and a possible trans-diagnostic phenotype that may elucidate shared risk factors for mechanisms of psychiatric illnesses. Scope and Methodology Using the examples of attention deficit hyperactivity disorder (ADHD) and autism spectrum disorders (ASD), we discuss RT variability. We first present a new meta-analysis of RT variability in ASD with and without comorbid ADHD. We then discuss potential mechanisms that may account for RT variability and statistical models that disentangle the cognitive processes affecting RTs. We then report a second meta-analysis comparing ADHD and non-ADHD children on diffusion model parameters. We consider how findings inform the search for neural correlates of RT variability. Findings Results suggest that RT variability is increased in ASD only when children with comorbid ADHD are included in the sample. Furthermore, RT variability in ADHD is explained by moderate to large increases (d = 0.63–0.99) in the ex-Gaussian parameter ? and the diffusion parameter drift rate, as well as by smaller differences (d = 0.32) in the diffusion parameter of nondecision time. The former may suggest problems in state regulation or arousal and difficulty detecting signal from noise, whereas the latter may reflect contributions from deficits in motor organization or output. The neuroimaging literature converges with this multicomponent interpretation and also highlights the role of top-down control circuits. Conclusion We underscore the importance of considering the interactions between top-down control, state regulation (e.g. arousal), and motor preparation when interpreting RT variability and conclude that decomposition of the RT signal provides superior interpretive power and suggests mechanisms convergent with those implicated using other cognitive paradigms. We conclude with specific recommendations for the field for next steps in the study of RT variability in neurodevelopmental disorders. En ligne : http://dx.doi.org/10.1111/jcpp.12217 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=234 Are Autistic Traits in the General Population Related to Global and Regional Brain Differences? / P. Cédric M. P. KOOLSCHIJN in Journal of Autism and Developmental Disorders, 45-9 (September 2015)
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Titre : Are Autistic Traits in the General Population Related to Global and Regional Brain Differences? Type de document : Texte imprimé et/ou numérique Auteurs : P. Cédric M. P. KOOLSCHIJN, Auteur ; Hilde M. GEURTS, Auteur ; Andries R. VAN DER LEIJ, Auteur ; H. Steven SCHOLTE, Auteur Article en page(s) : p.2779-2791 Langues : Anglais (eng) Mots-clés : Autistic traits Gray matter volume Cortical thickness Surface area Diffusion tensor imaging Autism Index. décimale : PER Périodiques Résumé : There is accumulating evidence that autistic-related traits in the general population lie on a continuum, with autism spectrum disorders representing the extreme end of this distribution. Here, we tested the hypothesis of a possible relationship between autistic traits and brain morphometry in the general population. Participants completed the short autism-spectrum quotient-questionnaire (AQ); T1-anatomical and DWI-scans were acquired. Associations between autistic traits and gray matter, and white matter microstructural-integrity were performed on the exploration-group (N = 204; 105 males, M-age = 22.85), and validated in the validation-group (N = 304; 155 males, M-age = 22.82). No significant associations were found between AQ-scores and brain morphometry in the exploration-group, or after pooling the data. This questions the assumption that autistic traits and their morphological associations do lie on a continuum in the general population. En ligne : http://dx.doi.org/10.1007/s10803-015-2441-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=267
in Journal of Autism and Developmental Disorders > 45-9 (September 2015) . - p.2779-2791[article] Are Autistic Traits in the General Population Related to Global and Regional Brain Differences? [Texte imprimé et/ou numérique] / P. Cédric M. P. KOOLSCHIJN, Auteur ; Hilde M. GEURTS, Auteur ; Andries R. VAN DER LEIJ, Auteur ; H. Steven SCHOLTE, Auteur . - p.2779-2791.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 45-9 (September 2015) . - p.2779-2791
Mots-clés : Autistic traits Gray matter volume Cortical thickness Surface area Diffusion tensor imaging Autism Index. décimale : PER Périodiques Résumé : There is accumulating evidence that autistic-related traits in the general population lie on a continuum, with autism spectrum disorders representing the extreme end of this distribution. Here, we tested the hypothesis of a possible relationship between autistic traits and brain morphometry in the general population. Participants completed the short autism-spectrum quotient-questionnaire (AQ); T1-anatomical and DWI-scans were acquired. Associations between autistic traits and gray matter, and white matter microstructural-integrity were performed on the exploration-group (N = 204; 105 males, M-age = 22.85), and validated in the validation-group (N = 304; 155 males, M-age = 22.82). No significant associations were found between AQ-scores and brain morphometry in the exploration-group, or after pooling the data. This questions the assumption that autistic traits and their morphological associations do lie on a continuum in the general population. En ligne : http://dx.doi.org/10.1007/s10803-015-2441-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=267 Brief Report: Inhibitory Control of Socially Relevant Stimuli in Children with High Functioning Autism / Hilde M. GEURTS in Journal of Autism and Developmental Disorders, 39-11 (November 2009)
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PermalinkCognitive Flexibility in ASD; Task Switching with Emotional Faces / Marieke VRIES in Journal of Autism and Developmental Disorders, 42-12 (December 2012)
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PermalinkComparison of network structures between autistic and non-autistic adults, and autism subgroups: A focus on demographic, psychological, and lifestyle factors / Tulsi A. RADHOE in Autism, 28-5 (May 2024)
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PermalinkContrasting deficits on executive functions between ADHD and reading disabled children / Gian Marco MARZOCCHI in Journal of Child Psychology and Psychiatry, 49-5 (May 2008)
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PermalinkPermalinkElderly with Autism: Executive Functions and Memory / Hilde M. GEURTS in Journal of Autism and Developmental Disorders, 42-5 (May 2012)
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PermalinkFinding Similarities in Differences Between Autistic Adults: Two Replicated Subgroups / Joost A. AGELINK VAN RENTERGEM ; Carolien TORENVLIET ; Annabeth P. GROENMAN ; Wikke J. VAN DER PUTTEN ; Hilde M. GEURTS in Journal of Autism and Developmental Disorders, 54-9 (September 2024)
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PermalinkFirst Psychometric Properties of the Dutch Interview for Diagnostic Assessment of Autism Spectrum Disorder in Adult Males Without Intellectual Disability / Richard VUIJK in Journal of Autism and Developmental Disorders, 52-8 (August 2022)
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PermalinkGoal-directed action control in children with autism spectrum disorders / Hilde M. GEURTS in Autism, 18-4 (May 2014)
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PermalinkGray Matter Characteristics in Mid and Old Aged Adults with ASD / P. Cédric M. P. KOOLSCHIJN in Journal of Autism and Developmental Disorders, 46-8 (August 2016)
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