Brief Report: Cognitive Flexibility in Autism Spectrum Disorders: A Quantitative Review / Rachel C. LEUNG in Journal of Autism and Developmental Disorders, 44-10 (October 2014)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 44-10 (October 2014) . - p.2628-2645 Titre : Brief Report: Cognitive Flexibility in Autism Spectrum Disorders: A Quantitative Review Type de document : Texte imprimé et/ou numérique Auteurs : Rachel C. LEUNG, Auteur ; Konstantine K. ZAKZANIS, Auteur Article en page(s) : p.2628-2645 Langues : Anglais (eng) Mots-clés : Cognitive flexibility  Autism spectrum disorders  ASD  Set-shifting  Meta-analysis Index. décimale : PER Périodiques Résumé : Impairments in cognitive flexibility have been used to characterize the neuropsychological presentation of persons with autism spectrum disorders (ASDs). Previous studies have yielded mixed results. Our objective was to systematically review the sensitivity of cognitive flexibility measures in ASD using quantitative methods employed by meta-analytic statistical techniques. Seventy-two studies met inclusion criteria for analysis and included a total of 2,137 individuals with ASD and 2,185 healthy controls. Our findings demonstrate that while the shift sub-scale of the self-report version of the Behavioral Rating Inventory of Executive Function (BRIEF) showed approximate absolute discriminability, of all the performance measures that were systematically reviewed and evaluated, none could reliably differentiate between individuals with ASD and controls; this is not surprising given that cognitive flexibility is not a core deficit of ASD. Our findings suggest that while the shift sub-scale of the self-report version of the BRIEF is a promising clinical marker, clinical performance measures of cognitive flexibility may lack ecological validity and lastly, reinforces that impairments in cognitive flexibility do not uniformly characterize all persons with ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2136-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241 [article] Brief Report: Cognitive Flexibility in Autism Spectrum Disorders: A Quantitative Review [Texte imprimé et/ou numérique] / Rachel C. LEUNG, Auteur ; Konstantine K. ZAKZANIS, Auteur . - p.2628-2645. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 44-10 (October 2014) . - p.2628-2645 Mots-clés : Cognitive flexibility  Autism spectrum disorders  ASD  Set-shifting  Meta-analysis Index. décimale : PER Périodiques Résumé : Impairments in cognitive flexibility have been used to characterize the neuropsychological presentation of persons with autism spectrum disorders (ASDs). Previous studies have yielded mixed results. Our objective was to systematically review the sensitivity of cognitive flexibility measures in ASD using quantitative methods employed by meta-analytic statistical techniques. Seventy-two studies met inclusion criteria for analysis and included a total of 2,137 individuals with ASD and 2,185 healthy controls. Our findings demonstrate that while the shift sub-scale of the self-report version of the Behavioral Rating Inventory of Executive Function (BRIEF) showed approximate absolute discriminability, of all the performance measures that were systematically reviewed and evaluated, none could reliably differentiate between individuals with ASD and controls; this is not surprising given that cognitive flexibility is not a core deficit of ASD. Our findings suggest that while the shift sub-scale of the self-report version of the BRIEF is a promising clinical marker, clinical performance measures of cognitive flexibility may lack ecological validity and lastly, reinforces that impairments in cognitive flexibility do not uniformly characterize all persons with ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2136-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241

Mapping the Network of Neuropsychological Impairment in Children with Autism Spectrum Disorder: A Graph Theoretical Analysis / George M. IBRAHIM in Journal of Autism and Developmental Disorders, 46-12 (December 2016)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 46-12 (December 2016) . - p.3770-3777 Titre : Mapping the Network of Neuropsychological Impairment in Children with Autism Spectrum Disorder: A Graph Theoretical Analysis Type de document : Texte imprimé et/ou numérique Auteurs : George M. IBRAHIM, Auteur ; Benjamin R. MORGAN, Auteur ; Vanessa M. VOGAN, Auteur ; Rachel C. LEUNG, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Margot J. TAYLOR, Auteur Article en page(s) : p.3770-3777 Langues : Anglais (eng) Mots-clés : ASD  Graph theory  Network analysis Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder (ASD) exhibit social-communicative impairments. Less is known about the neuropsychological profile of ASD, although cognitive and neuropsychological deficits are evident. We modelled neuropsychological function in 20 children with ASD and 20 sex, age and IQ matched typically-developing controls (ages 7–14) as a network of interacting parameters. Graph theoretical analysis was applied to identify critical topographic regions within this network. Two areas were significantly stronger hubs in typically-developing children, the ability to shift attention (p? En ligne : http://dx.doi.org/10.1007/s10803-016-2929-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=297 [article] Mapping the Network of Neuropsychological Impairment in Children with Autism Spectrum Disorder: A Graph Theoretical Analysis [Texte imprimé et/ou numérique] / George M. IBRAHIM, Auteur ; Benjamin R. MORGAN, Auteur ; Vanessa M. VOGAN, Auteur ; Rachel C. LEUNG, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Margot J. TAYLOR, Auteur . - p.3770-3777. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 46-12 (December 2016) . - p.3770-3777 Mots-clés : ASD  Graph theory  Network analysis Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder (ASD) exhibit social-communicative impairments. Less is known about the neuropsychological profile of ASD, although cognitive and neuropsychological deficits are evident. We modelled neuropsychological function in 20 children with ASD and 20 sex, age and IQ matched typically-developing controls (ages 7–14) as a network of interacting parameters. Graph theoretical analysis was applied to identify critical topographic regions within this network. Two areas were significantly stronger hubs in typically-developing children, the ability to shift attention (p? En ligne : http://dx.doi.org/10.1007/s10803-016-2929-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=297

Reduced beta connectivity during emotional face processing in adolescents with autism / Rachel C. LEUNG in Molecular Autism, (October 2014)  

Public ISBD [article]  inMolecular Autism > (October 2014) . - p.1-13 Titre : Reduced beta connectivity during emotional face processing in adolescents with autism Type de document : Texte imprimé et/ou numérique Auteurs : Rachel C. LEUNG, Auteur ; Annette X. YE, Auteur ; Simeon M. WONG, Auteur ; Margot J. TAYLOR, Auteur ; Sam M. DOESBURG, Auteur Article en page(s) : p.1-13 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social cognition. The biological basis of deficits in social cognition in ASD, and their difficulty in processing emotional face information in particular, remains unclear. Atypical communication within and between brain regions has been reported in ASD. Interregional phase-locking is a neurophysiological mechanism mediating communication among brain areas and is understood to support cognitive functions. In the present study we investigated interregional magnetoencephalographic phase synchronization during the perception of emotional faces in adolescents with ASD. En ligne : http://dx.doi.org/10.1186/2040-2392-5-51 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276 [article] Reduced beta connectivity during emotional face processing in adolescents with autism [Texte imprimé et/ou numérique] / Rachel C. LEUNG, Auteur ; Annette X. YE, Auteur ; Simeon M. WONG, Auteur ; Margot J. TAYLOR, Auteur ; Sam M. DOESBURG, Auteur . - p.1-13. Langues : Anglais (eng) in Molecular Autism > (October 2014) . - p.1-13 Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social cognition. The biological basis of deficits in social cognition in ASD, and their difficulty in processing emotional face information in particular, remains unclear. Atypical communication within and between brain regions has been reported in ASD. Interregional phase-locking is a neurophysiological mechanism mediating communication among brain areas and is understood to support cognitive functions. In the present study we investigated interregional magnetoencephalographic phase synchronization during the perception of emotional faces in adolescents with ASD. En ligne : http://dx.doi.org/10.1186/2040-2392-5-51 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276

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