A description of medical conditions in adults with autism spectrum disorder: A follow-up of the 1980s Utah/UCLA Autism Epidemiologic Study / Kyle B. JONES in Autism, 20-5 (July 2016)  

Public ISBD [article]  inAutism > 20-5 (July 2016) . - p.551-561 Titre : A description of medical conditions in adults with autism spectrum disorder: A follow-up of the 1980s Utah/UCLA Autism Epidemiologic Study Type de document : texte imprimé Auteurs : Kyle B. JONES, Auteur ; Kristina J. COTTLE, Auteur ; Amanda V. BAKIAN, Auteur ; Megan FARLEY, Auteur ; Deborah A. BILDER, Auteur ; Hilary H. COON, Auteur ; William M MCMAHON, Auteur Article en page(s) : p.551-561 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  medical comorbidity Index. décimale : PER Périodiques Résumé : This study describes medical conditions experienced by a population-based cohort of adults with autism spectrum disorder whose significant developmental concerns were apparent during childhood. As part of a 25-year outcome study of autism spectrum disorder in adulthood, medical histories were collected on 92 participants (N = 69 males) who were first ascertained as children in the mid-1980s, 11 of whom were deceased at the time of follow-up. Questionnaires queried medical symptoms, disorders, hospitalizations, surgeries, and medication use. Median age at follow-up was 36 years (range: 23.5–50.5 years), and intellectual disability co-occurred in 62%. The most common medical conditions were seizures, obesity, insomnia, and constipation. The median number of medical conditions per person was 11. Increased medical comorbidity was associated with female gender (p = 0.01) and obesity (p = 0.03), but not intellectual disability (p = 0.79). Adults in this cohort of autism spectrum disorder first ascertained in the 1980s experience a high number of chronic medical conditions, regardless of intellectual ability. Understanding of these conditions commonly experienced should direct community-based and medical primary care for this population. En ligne : http://dx.doi.org/10.1177/1362361315594798 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290 [article] A description of medical conditions in adults with autism spectrum disorder: A follow-up of the 1980s Utah/UCLA Autism Epidemiologic Study [texte imprimé] / Kyle B. JONES, Auteur ; Kristina J. COTTLE, Auteur ; Amanda V. BAKIAN, Auteur ; Megan FARLEY, Auteur ; Deborah A. BILDER, Auteur ; Hilary H. COON, Auteur ; William M MCMAHON, Auteur . - p.551-561. Langues : Anglais (eng) in Autism > 20-5 (July 2016) . - p.551-561 Mots-clés : autism spectrum disorder  medical comorbidity Index. décimale : PER Périodiques Résumé : This study describes medical conditions experienced by a population-based cohort of adults with autism spectrum disorder whose significant developmental concerns were apparent during childhood. As part of a 25-year outcome study of autism spectrum disorder in adulthood, medical histories were collected on 92 participants (N = 69 males) who were first ascertained as children in the mid-1980s, 11 of whom were deceased at the time of follow-up. Questionnaires queried medical symptoms, disorders, hospitalizations, surgeries, and medication use. Median age at follow-up was 36 years (range: 23.5–50.5 years), and intellectual disability co-occurred in 62%. The most common medical conditions were seizures, obesity, insomnia, and constipation. The median number of medical conditions per person was 11. Increased medical comorbidity was associated with female gender (p = 0.01) and obesity (p = 0.03), but not intellectual disability (p = 0.79). Adults in this cohort of autism spectrum disorder first ascertained in the 1980s experience a high number of chronic medical conditions, regardless of intellectual ability. Understanding of these conditions commonly experienced should direct community-based and medical primary care for this population. En ligne : http://dx.doi.org/10.1177/1362361315594798 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290

Mid‐life social outcomes for a population‐based sample of adults with ASD / Megan FARLEY in Autism Research, 11-1 (January 2018)  

Public ISBD [article]  inAutism Research > 11-1 (January 2018) . - p.142-152 Titre : Mid‐life social outcomes for a population‐based sample of adults with ASD Type de document : texte imprimé Auteurs : Megan FARLEY, Auteur ; Kristina J. COTTLE, Auteur ; Deborah A. BILDER, Auteur ; Joseph VISKOCHIL, Auteur ; Hilary H. COON, Auteur ; William MCMAHON, Auteur Article en page(s) : p.142-152 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Adults with autism spectrum disorders (ASD) fall short of social outcomes of non‐ASD peers in mid‐life, as documented by currently published research. The aim of the current study was to extend what is known about social functioning, employment, independent living, and use of social services by examining details of the current life status for a population‐based sample of adults with ASD (mean age = 35.5 years, range = 22.2–51.4). We collected outcome data via direct assessment and informant report for 169 individuals. Three‐fourths of the sample had cognitive abilities in the intellectually disabled range. Social functioning outcomes, as a single measure, mirror those reported previously for other samples, including samples with a high proportion of individuals with normal range intellectual abilities, with 20% achieving the most independent outcomes and 46% requiring high levels of support across most life areas. Participant subgroups who achieved maximal outcomes represented a range of social and intellectual abilities for several outcome metrics. Participants used high levels of public and private supports, yet specific areas of clear, unmet need were also identified. Autism Res 2018, 11: 142–152. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. Lay Summary This paper describes the social functioning outcomes for 169 adults with autism spectrum disorders in mid‐life. Adult participants spanned the full range of functional and cognitive ability levels, with over 75% functioning in the cognitively impaired range. While summary descriptions of outcomes for this sample were similar to those reported for other groups of adults, this report provides detailed information regarding employment outcomes, social relationships, leisure activities, participation in the community, residential situations, public service use, and involvement with law enforcement. En ligne : https://doi.org/10.1002/aur.1897 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=334 [article] Mid‐life social outcomes for a population‐based sample of adults with ASD [texte imprimé] / Megan FARLEY, Auteur ; Kristina J. COTTLE, Auteur ; Deborah A. BILDER, Auteur ; Joseph VISKOCHIL, Auteur ; Hilary H. COON, Auteur ; William MCMAHON, Auteur . - p.142-152. Langues : Anglais (eng) in Autism Research > 11-1 (January 2018) . - p.142-152 Index. décimale : PER Périodiques Résumé : Adults with autism spectrum disorders (ASD) fall short of social outcomes of non‐ASD peers in mid‐life, as documented by currently published research. The aim of the current study was to extend what is known about social functioning, employment, independent living, and use of social services by examining details of the current life status for a population‐based sample of adults with ASD (mean age = 35.5 years, range = 22.2–51.4). We collected outcome data via direct assessment and informant report for 169 individuals. Three‐fourths of the sample had cognitive abilities in the intellectually disabled range. Social functioning outcomes, as a single measure, mirror those reported previously for other samples, including samples with a high proportion of individuals with normal range intellectual abilities, with 20% achieving the most independent outcomes and 46% requiring high levels of support across most life areas. Participant subgroups who achieved maximal outcomes represented a range of social and intellectual abilities for several outcome metrics. Participants used high levels of public and private supports, yet specific areas of clear, unmet need were also identified. Autism Res 2018, 11: 142–152. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. Lay Summary This paper describes the social functioning outcomes for 169 adults with autism spectrum disorders in mid‐life. Adult participants spanned the full range of functional and cognitive ability levels, with over 75% functioning in the cognitively impaired range. While summary descriptions of outcomes for this sample were similar to those reported for other groups of adults, this report provides detailed information regarding employment outcomes, social relationships, leisure activities, participation in the community, residential situations, public service use, and involvement with law enforcement. En ligne : https://doi.org/10.1002/aur.1897 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=334

Psychiatric Comorbidity and Medication Use in Adults with Autism Spectrum Disorder / Tara R. BUCK in Journal of Autism and Developmental Disorders, 44-12 (December 2014)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 44-12 (December 2014) . - p.3063-3071 Titre : Psychiatric Comorbidity and Medication Use in Adults with Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Tara R. BUCK, Auteur ; Joseph VISKOCHIL, Auteur ; Megan FARLEY, Auteur ; Hilary H. COON, Auteur ; William M. MCMAHON, Auteur ; Jubel MORGAN, Auteur ; Deborah A. BILDER, Auteur Article en page(s) : p.3063-3071 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Psychiatric comorbidity  Psychotropic medication  Intellectual disability Index. décimale : PER Périodiques Résumé : The purpose of this study was to investigate comorbid psychiatric disorders and psychotropic medication use among adults with autism spectrum disorder (ASD) ascertained as children during a 1980’s statewide Utah autism prevalence study (n = 129). Seventy-three individuals (56.6 %) met criteria for a current psychiatric disorder; 89 participants (69.0 %) met lifetime criteria for a psychiatric disorder. Caregivers reported a psychiatric diagnosis in 44 participants (34.1 %). Anxiety disorder had the highest current and lifetime prevalence (39.5 and 52.7 %, respectively). Participants with intellectual disability (n = 94, 72.8 %) were significantly less likely to have community-based diagnoses of anxiety (χ2 = 5.37, p = 0.02) or depression (χ2 = 13.18, p 0.001) reported by caregivers. Seventy-six participants (58.9 %) were taking ≥1 psychotropic medication. Comorbid psychiatric disorders occur frequently in adults with ASD, though identifying these disorders poses a challenge in community settings. A greater understanding of the presentation of these conditions within this population will increase assessment validity and the potential for efficacious intervention. En ligne : http://dx.doi.org/10.1007/s10803-014-2170-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=243 [article] Psychiatric Comorbidity and Medication Use in Adults with Autism Spectrum Disorder [texte imprimé] / Tara R. BUCK, Auteur ; Joseph VISKOCHIL, Auteur ; Megan FARLEY, Auteur ; Hilary H. COON, Auteur ; William M. MCMAHON, Auteur ; Jubel MORGAN, Auteur ; Deborah A. BILDER, Auteur . - p.3063-3071. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 44-12 (December 2014) . - p.3063-3071 Mots-clés : Autism spectrum disorder  Psychiatric comorbidity  Psychotropic medication  Intellectual disability Index. décimale : PER Périodiques Résumé : The purpose of this study was to investigate comorbid psychiatric disorders and psychotropic medication use among adults with autism spectrum disorder (ASD) ascertained as children during a 1980’s statewide Utah autism prevalence study (n = 129). Seventy-three individuals (56.6 %) met criteria for a current psychiatric disorder; 89 participants (69.0 %) met lifetime criteria for a psychiatric disorder. Caregivers reported a psychiatric diagnosis in 44 participants (34.1 %). Anxiety disorder had the highest current and lifetime prevalence (39.5 and 52.7 %, respectively). Participants with intellectual disability (n = 94, 72.8 %) were significantly less likely to have community-based diagnoses of anxiety (χ2 = 5.37, p = 0.02) or depression (χ2 = 13.18, p 0.001) reported by caregivers. Seventy-six participants (58.9 %) were taking ≥1 psychotropic medication. Comorbid psychiatric disorders occur frequently in adults with ASD, though identifying these disorders poses a challenge in community settings. A greater understanding of the presentation of these conditions within this population will increase assessment validity and the potential for efficacious intervention. En ligne : http://dx.doi.org/10.1007/s10803-014-2170-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=243

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