Prenatal and Neonatal Thyroid Stimulating Hormone Levels and Autism Spectrum Disorders / Vincent M. YAU in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.719-730 Titre : Prenatal and Neonatal Thyroid Stimulating Hormone Levels and Autism Spectrum Disorders Type de document : texte imprimé Auteurs : Vincent M. YAU, Auteur ; Marta LUTSKY, Auteur ; Cathleen K. YOSHIDA, Auteur ; Bill LASLEY, Auteur ; Martin KHARRAZI, Auteur ; Gayle WINDHAM, Auteur ; Nancy GEE, Auteur ; Lisa A. CROEN, Auteur Article en page(s) : p.719-730 Langues : Anglais (eng) Mots-clés : Thyroid  Thyroid stimulating hormone  Autism  Pregnancy  Developmental delay Index. décimale : PER Périodiques Résumé : Thyroid hormones are critical for normal brain development. This study examined autism spectrum disorders (ASD) and thyroid stimulating hormone (TSH) levels measured in mid-pregnancy maternal serum and infant blood after birth. Three groups of children born in Orange County, CA in 2000–2001were identified: ASD (n = 78), developmental delay (n = 45), and general population controls (GP) (n = 149). Samples were retrieved from prenatal and newborn screening specimen archives. Adjusted logistic regression models showed inverse associations between ASD and log transformed TSH levels in maternal serum samples (ASD vs. GP: OR [95 % CI] 0.33 [0.12–0.91], Early Onset ASD vs. GP: 0.31 [0.10–0.98]). Results for thyroid levels in newborn blood samples were similar though not significant (ASD vs. GP: 0.61 [0.18–2.04]). En ligne : http://dx.doi.org/10.1007/s10803-014-2227-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Prenatal and Neonatal Thyroid Stimulating Hormone Levels and Autism Spectrum Disorders [texte imprimé] / Vincent M. YAU, Auteur ; Marta LUTSKY, Auteur ; Cathleen K. YOSHIDA, Auteur ; Bill LASLEY, Auteur ; Martin KHARRAZI, Auteur ; Gayle WINDHAM, Auteur ; Nancy GEE, Auteur ; Lisa A. CROEN, Auteur . - p.719-730. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.719-730 Mots-clés : Thyroid  Thyroid stimulating hormone  Autism  Pregnancy  Developmental delay Index. décimale : PER Périodiques Résumé : Thyroid hormones are critical for normal brain development. This study examined autism spectrum disorders (ASD) and thyroid stimulating hormone (TSH) levels measured in mid-pregnancy maternal serum and infant blood after birth. Three groups of children born in Orange County, CA in 2000–2001were identified: ASD (n = 78), developmental delay (n = 45), and general population controls (GP) (n = 149). Samples were retrieved from prenatal and newborn screening specimen archives. Adjusted logistic regression models showed inverse associations between ASD and log transformed TSH levels in maternal serum samples (ASD vs. GP: OR [95 % CI] 0.33 [0.12–0.91], Early Onset ASD vs. GP: 0.31 [0.10–0.98]). Results for thyroid levels in newborn blood samples were similar though not significant (ASD vs. GP: 0.61 [0.18–2.04]). En ligne : http://dx.doi.org/10.1007/s10803-014-2227-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Validation of Autism Spectrum Disorder Diagnoses in Large Healthcare Systems with Electronic Medical Records / Karen J. COLEMAN in Journal of Autism and Developmental Disorders, 45-7 (July 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-7 (July 2015) . - p.1989-1996 Titre : Validation of Autism Spectrum Disorder Diagnoses in Large Healthcare Systems with Electronic Medical Records Type de document : texte imprimé Auteurs : Karen J. COLEMAN, Auteur ; Marta LUTSKY, Auteur ; Vincent YAU, Auteur ; Yinge QIAN, Auteur ; Magdalena E. POMICHOWSKI, Auteur ; Phillip M. CRAWFORD, Auteur ; Frances L. LYNCH, Auteur ; Jeanne M. MADDEN, Auteur ; Ashli A. OWEN-SMITH, Auteur ; John A. PEARSON, Auteur ; Kathryn A. PEARSON, Auteur ; Donna RUSINAK, Auteur ; Virginia P. QUINN, Auteur ; Lisa A. CROEN, Auteur Année de publication : 2015 Article en page(s) : p.1989-1996 Langues : Anglais (eng) Mots-clés : Population-based  Racial/ethnic minorities  Chart review  Children  Adolescents Index. décimale : PER Périodiques Résumé : To identify factors associated with valid Autism Spectrum Disorder (ASD) diagnoses from electronic sources in large healthcare systems. We examined 1,272 charts from ASD diagnosed youth <18 years old. Expert reviewers classified diagnoses as confirmed, probable, possible, ruled out, or not enough information. A total of 845 were classified with 81 % as a confirmed, probable, or possible ASD diagnosis. The predictors of valid ASD diagnoses were >2 diagnoses in the medical record (OR 2.94; 95 % CI 2.03–4.25; p < 0.001) and being male (OR 1.51; 95 % CI 1.05–2.17; p = 0.03). In large integrated healthcare settings, at least two diagnoses can be used to identify ASD patients for population-based research. En ligne : http://dx.doi.org/10.1007/s10803-015-2358-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=261 [article] Validation of Autism Spectrum Disorder Diagnoses in Large Healthcare Systems with Electronic Medical Records [texte imprimé] / Karen J. COLEMAN, Auteur ; Marta LUTSKY, Auteur ; Vincent YAU, Auteur ; Yinge QIAN, Auteur ; Magdalena E. POMICHOWSKI, Auteur ; Phillip M. CRAWFORD, Auteur ; Frances L. LYNCH, Auteur ; Jeanne M. MADDEN, Auteur ; Ashli A. OWEN-SMITH, Auteur ; John A. PEARSON, Auteur ; Kathryn A. PEARSON, Auteur ; Donna RUSINAK, Auteur ; Virginia P. QUINN, Auteur ; Lisa A. CROEN, Auteur . - 2015 . - p.1989-1996. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-7 (July 2015) . - p.1989-1996 Mots-clés : Population-based  Racial/ethnic minorities  Chart review  Children  Adolescents Index. décimale : PER Périodiques Résumé : To identify factors associated with valid Autism Spectrum Disorder (ASD) diagnoses from electronic sources in large healthcare systems. We examined 1,272 charts from ASD diagnosed youth <18 years old. Expert reviewers classified diagnoses as confirmed, probable, possible, ruled out, or not enough information. A total of 845 were classified with 81 % as a confirmed, probable, or possible ASD diagnosis. The predictors of valid ASD diagnoses were >2 diagnoses in the medical record (OR 2.94; 95 % CI 2.03–4.25; p < 0.001) and being male (OR 1.51; 95 % CI 1.05–2.17; p = 0.03). In large integrated healthcare settings, at least two diagnoses can be used to identify ASD patients for population-based research. En ligne : http://dx.doi.org/10.1007/s10803-015-2358-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=261

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