Follow-up of the Cool Little Kids translational trial into middle childhood / Jordana K. BAYER in Journal of Child Psychology and Psychiatry, 63-1 (January 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-1 (January 2022) . - p.88-98 Titre : Follow-up of the Cool Little Kids translational trial into middle childhood Type de document : texte imprimé Auteurs : Jordana K. BAYER, Auteur ; Amy BROWN, Auteur ; Luke A. PRENDERGAST, Auteur ; Lesley BRETHERTON, Auteur ; Harriet HISCOCK, Auteur ; Cathrine MIHALOPOULOS, Auteur ; Margaret NELSON-LOWE, Auteur ; Tamsyn GILBERTSON, Auteur ; Kate NOONE, Auteur ; Natalie L. BISCHOF, Auteur ; Cassima BEECHEY, Auteur ; Fenny MULIADI, Auteur ; Ronald M. RAPEE, Auteur Article en page(s) : p.88-98 Langues : Anglais (eng) Mots-clés : Anxiety  Anxiety Disorders/diagnosis  Child  Child Behavior  Child, Preschool  Follow-Up Studies  Humans  Parenting  Internalising problems  anxiety disorders  prevention  randomised controlled trial  translation Index. décimale : PER Périodiques Résumé : BACKGROUND: Public health advocates have highlighted internalising problems as a leading cause of global burden of disease. Internalising problems (anxiety/depression) affect up to 20% of school-age children and can impact peer relations, school engagement and later employment and mortality. This translational trial aimed to determine whether a selective/indicated parenting group programme to prevent internalising distress in shy/inhibited preschool children had sustained effects in middle childhood. Translational design aspects were a brief parent-report screening tool for child inhibition offered universally across the population via preschools in the year before school, followed by an invitation to parents of all inhibited children to attend the parenting programme at venues in their local community. METHODS: Design of the study was a randomised controlled trial. The setting was 307 preschool services across eight socioeconomically diverse government areas in Melbourne, Australia. Participants were 545 parents of inhibited four-year-old children of which 456 (84%) were retained during middle childhood (age of seven to 10 years). Early intervention was the Cool Little Kids parenting group programme, and control was 'usual care' access to available support services in the community. Primary outcomes were child anxiety and depression symptoms (parent and child report) and DSM-IV anxiety disorders (assessor masked). Secondary outcomes were parenting practices and parent mental health. RESULTS: There was no significant difference in anxiety disorders between the intervention and control group during the three annual follow-ups of the cohort in middle childhood (2015 43% vs. 41%, 2016 40% vs. 36%, 2017 27% vs. 30%, respectively; p's > .05). There were also no significant differences in child anxiety or depression symptoms (by child or parent report), parenting practices or parent mental health, between the intervention and control group during middle childhood. However, a priori interaction tests suggested that for children with anxious parents, early intervention attenuated risk for middle childhood internalising problems. CONCLUSIONS: An issue for population translation is low levels of parent engagement in preventive interventions. Initial effects of the Cool Little Kids parenting group programme in reducing shy/inhibited preschool children's internalising distress at school entry dissipated over time, perhaps due to low engagement. Future translational research on early prevention of internalising problems could benefit from screening preschool children in the population at higher risk (combining temperamental inhibition and parent distress) and incorporating motivational techniques to facilitate family engagement. Trial registration ISRCTN30996662 http://www.isrctn.com/ISRCTN30996662. En ligne : http://dx.doi.org/10.1111/jcpp.13464 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 [article] Follow-up of the Cool Little Kids translational trial into middle childhood [texte imprimé] / Jordana K. BAYER, Auteur ; Amy BROWN, Auteur ; Luke A. PRENDERGAST, Auteur ; Lesley BRETHERTON, Auteur ; Harriet HISCOCK, Auteur ; Cathrine MIHALOPOULOS, Auteur ; Margaret NELSON-LOWE, Auteur ; Tamsyn GILBERTSON, Auteur ; Kate NOONE, Auteur ; Natalie L. BISCHOF, Auteur ; Cassima BEECHEY, Auteur ; Fenny MULIADI, Auteur ; Ronald M. RAPEE, Auteur . - p.88-98. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-1 (January 2022) . - p.88-98 Mots-clés : Anxiety  Anxiety Disorders/diagnosis  Child  Child Behavior  Child, Preschool  Follow-Up Studies  Humans  Parenting  Internalising problems  anxiety disorders  prevention  randomised controlled trial  translation Index. décimale : PER Périodiques Résumé : BACKGROUND: Public health advocates have highlighted internalising problems as a leading cause of global burden of disease. Internalising problems (anxiety/depression) affect up to 20% of school-age children and can impact peer relations, school engagement and later employment and mortality. This translational trial aimed to determine whether a selective/indicated parenting group programme to prevent internalising distress in shy/inhibited preschool children had sustained effects in middle childhood. Translational design aspects were a brief parent-report screening tool for child inhibition offered universally across the population via preschools in the year before school, followed by an invitation to parents of all inhibited children to attend the parenting programme at venues in their local community. METHODS: Design of the study was a randomised controlled trial. The setting was 307 preschool services across eight socioeconomically diverse government areas in Melbourne, Australia. Participants were 545 parents of inhibited four-year-old children of which 456 (84%) were retained during middle childhood (age of seven to 10 years). Early intervention was the Cool Little Kids parenting group programme, and control was 'usual care' access to available support services in the community. Primary outcomes were child anxiety and depression symptoms (parent and child report) and DSM-IV anxiety disorders (assessor masked). Secondary outcomes were parenting practices and parent mental health. RESULTS: There was no significant difference in anxiety disorders between the intervention and control group during the three annual follow-ups of the cohort in middle childhood (2015 43% vs. 41%, 2016 40% vs. 36%, 2017 27% vs. 30%, respectively; p's > .05). There were also no significant differences in child anxiety or depression symptoms (by child or parent report), parenting practices or parent mental health, between the intervention and control group during middle childhood. However, a priori interaction tests suggested that for children with anxious parents, early intervention attenuated risk for middle childhood internalising problems. CONCLUSIONS: An issue for population translation is low levels of parent engagement in preventive interventions. Initial effects of the Cool Little Kids parenting group programme in reducing shy/inhibited preschool children's internalising distress at school entry dissipated over time, perhaps due to low engagement. Future translational research on early prevention of internalising problems could benefit from screening preschool children in the population at higher risk (combining temperamental inhibition and parent distress) and incorporating motivational techniques to facilitate family engagement. Trial registration ISRCTN30996662 http://www.isrctn.com/ISRCTN30996662. En ligne : http://dx.doi.org/10.1111/jcpp.13464 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456

Randomised Controlled Trial of a Behavioural Sleep Intervention, ?Sleeping Sound?, for Autistic Children: 12-Month Outcomes and Moderators of Treatment / Nicole PAPADOPOULOS ; Matthew FULLER-TYSZKIEWICZ ; Emma SCIBERRAS ; Harriet HISCOCK ; Katrina WILLIAMS ; Jane MCGILLIVRAY ; Cathrine MIHALOPOULOS ; Susannah T. BELLOWS ; Deborah MARKS ; Patricia HOWLIN ; Nicole J. RINEHART in Journal of Autism and Developmental Disorders, 54-2 (February 2024)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 54-2 (February 2024) . - p.442-457 Titre : Randomised Controlled Trial of a Behavioural Sleep Intervention, ?Sleeping Sound?, for Autistic Children: 12-Month Outcomes and Moderators of Treatment Type de document : texte imprimé Auteurs : Nicole PAPADOPOULOS, Auteur ; Matthew FULLER-TYSZKIEWICZ, Auteur ; Emma SCIBERRAS, Auteur ; Harriet HISCOCK, Auteur ; Katrina WILLIAMS, Auteur ; Jane MCGILLIVRAY, Auteur ; Cathrine MIHALOPOULOS, Auteur ; Susannah T. BELLOWS, Auteur ; Deborah MARKS, Auteur ; Patricia HOWLIN, Auteur ; Nicole J. RINEHART, Auteur Article en page(s) : p.442-457 Index. décimale : PER Périodiques Résumé : This study examined the sustained and moderating effects of a behavioural sleep intervention for autistic children in a randomised controlled trial. Autistic children (5 13 years) with sleep problems were randomised to the Sleeping Sound intervention or Treatment as Usual (TAU). At 12-month follow-up (n 150), caregivers of children in the Sleeping Sound group reported greater reduction in child sleep problems compared to TAU (p < .001, effect size: ? 0.4). The long-term benefits of the intervention were greater for children taking sleep medication, children of parents who were not experiencing psychological distress, and children with greater autism severity. The Sleeping Sound intervention demonstrated sustained improvements in child sleep. Identified moderators may inform treatment by indicating which subgroups may benefit from further support. En ligne : https://doi.org/10.1007/s10803-022-05809-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=520 [article] Randomised Controlled Trial of a Behavioural Sleep Intervention, ?Sleeping Sound?, for Autistic Children: 12-Month Outcomes and Moderators of Treatment [texte imprimé] / Nicole PAPADOPOULOS, Auteur ; Matthew FULLER-TYSZKIEWICZ, Auteur ; Emma SCIBERRAS, Auteur ; Harriet HISCOCK, Auteur ; Katrina WILLIAMS, Auteur ; Jane MCGILLIVRAY, Auteur ; Cathrine MIHALOPOULOS, Auteur ; Susannah T. BELLOWS, Auteur ; Deborah MARKS, Auteur ; Patricia HOWLIN, Auteur ; Nicole J. RINEHART, Auteur . - p.442-457. in Journal of Autism and Developmental Disorders > 54-2 (February 2024) . - p.442-457 Index. décimale : PER Périodiques Résumé : This study examined the sustained and moderating effects of a behavioural sleep intervention for autistic children in a randomised controlled trial. Autistic children (5 13 years) with sleep problems were randomised to the Sleeping Sound intervention or Treatment as Usual (TAU). At 12-month follow-up (n 150), caregivers of children in the Sleeping Sound group reported greater reduction in child sleep problems compared to TAU (p < .001, effect size: ? 0.4). The long-term benefits of the intervention were greater for children taking sleep medication, children of parents who were not experiencing psychological distress, and children with greater autism severity. The Sleeping Sound intervention demonstrated sustained improvements in child sleep. Identified moderators may inform treatment by indicating which subgroups may benefit from further support. En ligne : https://doi.org/10.1007/s10803-022-05809-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=520

Sleeping Sound Autism Spectrum Disorder (ASD): Cost-Effectiveness of a Brief Behavioural Sleep Intervention in Primary School-Aged Autistic Children / Lidia ENGEL in Journal of Autism and Developmental Disorders, 55-9 (September 2025)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 55-9 (September 2025) . - p.3028-3039 Titre : Sleeping Sound Autism Spectrum Disorder (ASD): Cost-Effectiveness of a Brief Behavioural Sleep Intervention in Primary School-Aged Autistic Children Type de document : texte imprimé Auteurs : Lidia ENGEL, Auteur ; Oxana CHIOTELIS, Auteur ; Nicole PAPADOPOULOS, Auteur ; Harriet HISCOCK, Auteur ; Patricia HOWLIN, Auteur ; Jane MCGILLIVRAY, Auteur ; Susannah T. BELLOWS, Auteur ; Nicole J. RINEHART, Auteur ; Cathrine MIHALOPOULOS, Auteur Article en page(s) : p.3028-3039 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Disordered sleep is common in autistic children. This study aimed to evaluate the cost-effectiveness of a brief behavioural sleep intervention, the 'Sleeping Sound intervention', in primary school-aged autistic children in Australia. A cost-effectiveness analysis was undertaken alongside a randomised controlled trial over a 6-month follow-up period from both a societal and healthcare sector perspective. Resources used by participants were collected from a resource-use questionnaire and administrative data; intervention costs were determined from study records. Mean costs and quality-adjusted life-years (QALYs) were compared between the intervention and treatment as usual (TAU) groups. Uncertainty analysis using bootstrapping and sensitivity analyses were conducted. The sample included 245 children, with 123 participants randomised to the intervention group and 122 to TAU. The mean total costs were higher for the Sleeping Sound intervention with a mean difference of A$745 (95% CI 248; 1242; p = 0.003) from a healthcare sector perspective and A$1310 (95% CI 584; 2035, p < 0.001) from a societal perspective. However, the intervention also resulted in greater QALYs compared with TAU, with a mean difference of 0.038 (95% CI 0.004; 0.072; p = 0.028). The incremental cost-effectiveness ratio was A$24,419/QALY (95% CI 23,135; 25,703) from a healthcare sector perspective and A$41,922/QALY (95% CI 39,915; 43,928) from a societal perspective; with a probability of being cost-effective of 93.8% and 74.7%, respectively. Findings remained robust in the sensitivity analyses. The Sleeping Sound intervention offers a cost-effective approach in improving sleep in primary school-aged autistic children. En ligne : https://doi.org/10.1007/s10803-024-06422-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=566 [article] Sleeping Sound Autism Spectrum Disorder (ASD): Cost-Effectiveness of a Brief Behavioural Sleep Intervention in Primary School-Aged Autistic Children [texte imprimé] / Lidia ENGEL, Auteur ; Oxana CHIOTELIS, Auteur ; Nicole PAPADOPOULOS, Auteur ; Harriet HISCOCK, Auteur ; Patricia HOWLIN, Auteur ; Jane MCGILLIVRAY, Auteur ; Susannah T. BELLOWS, Auteur ; Nicole J. RINEHART, Auteur ; Cathrine MIHALOPOULOS, Auteur . - p.3028-3039. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 55-9 (September 2025) . - p.3028-3039 Index. décimale : PER Périodiques Résumé : Disordered sleep is common in autistic children. This study aimed to evaluate the cost-effectiveness of a brief behavioural sleep intervention, the 'Sleeping Sound intervention', in primary school-aged autistic children in Australia. A cost-effectiveness analysis was undertaken alongside a randomised controlled trial over a 6-month follow-up period from both a societal and healthcare sector perspective. Resources used by participants were collected from a resource-use questionnaire and administrative data; intervention costs were determined from study records. Mean costs and quality-adjusted life-years (QALYs) were compared between the intervention and treatment as usual (TAU) groups. Uncertainty analysis using bootstrapping and sensitivity analyses were conducted. The sample included 245 children, with 123 participants randomised to the intervention group and 122 to TAU. The mean total costs were higher for the Sleeping Sound intervention with a mean difference of A$745 (95% CI 248; 1242; p = 0.003) from a healthcare sector perspective and A$1310 (95% CI 584; 2035, p < 0.001) from a societal perspective. However, the intervention also resulted in greater QALYs compared with TAU, with a mean difference of 0.038 (95% CI 0.004; 0.072; p = 0.028). The incremental cost-effectiveness ratio was A$24,419/QALY (95% CI 23,135; 25,703) from a healthcare sector perspective and A$41,922/QALY (95% CI 39,915; 43,928) from a societal perspective; with a probability of being cost-effective of 93.8% and 74.7%, respectively. Findings remained robust in the sensitivity analyses. The Sleeping Sound intervention offers a cost-effective approach in improving sleep in primary school-aged autistic children. En ligne : https://doi.org/10.1007/s10803-024-06422-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=566

Sleeping Sound Autism Spectrum Disorder (ASD): a randomised controlled trial of a brief behavioural sleep intervention in primary school-aged autistic children / Nicole PAPADOPOULOS in Journal of Child Psychology and Psychiatry, 63-11 (November 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-11 (November 2022) . - p.1423-1433 Titre : Sleeping Sound Autism Spectrum Disorder (ASD): a randomised controlled trial of a brief behavioural sleep intervention in primary school-aged autistic children Type de document : texte imprimé Auteurs : Nicole PAPADOPOULOS, Auteur ; Emma SCIBERRAS, Auteur ; Harriet HISCOCK, Auteur ; Katrina WILLIAMS, Auteur ; Jane MCGILLIVRAY, Auteur ; Cathrine MIHALOPOULOS, Auteur ; Lidia ENGEL, Auteur ; Matthew FULLER-TYSZKIEWICZ, Auteur ; Susannah T. BELLOWS, Auteur ; Deborah MARKS, Auteur ; Patricia HOWLIN, Auteur ; Nicole J. RINEHART, Auteur Article en page(s) : p.1423-1433 Langues : Anglais (eng) Mots-clés : Child  Humans  Child, Preschool  Adolescent  Autism Spectrum Disorder/complications/therapy/psychology  Quality of Life  Autistic Disorder/complications  Australia  Sleep  Sleep Wake Disorders/therapy/complications  Schools  Autism spectrum disorders  RCT design  intervention  treatment trial Index. décimale : PER Périodiques Résumé : BACKGROUND: Behavioural sleep problems are common in children with autism spectrum disorder (ASD); however, evidence for the efficacy of behavioural sleep interventions is limited. This study examined the efficacy of a brief behavioural sleep intervention in autistic children. It was hypothesised that the intervention would reduce overall child sleep problems (primary outcome), in addition to improvements in children's social, emotional, cognitive, academic functioning, and quality of life, and parent/caregivers' stress, quality of life, and mental health (secondary outcomes). METHODS: A randomised controlled trial was conducted with participants randomised via a computer-generated sequence to the sleeping sound intervention (n=123) or treatment as usual (n=122) group. Participants comprised 245 children with an ASD diagnosis. Inclusion criteria were as follows: confirmation of DSM IV or DSM-5 diagnosis of ASD, participants aged between 5 and 13 years and parent/caregiver report of moderate-severe sleep problems. Exclusion criteria were as follows: parent/caregiver intellectual disability or lacking sufficient English to complete questionnaires; and child participant with co-occurring medical conditions known to impact sleep. The intervention group received the sleeping sound intervention (2 × 50-min face-to-face sessions plus follow-up phone call) by a trained clinician. RESULTS: Change in children's sleep problems was measured by the Children's Sleep Habits Questionnaire (CSHQ) at 3 months post randomisation. Parents/caregivers of children in the intervention group reported a reduction in child sleep problems at 3 months post randomisation (effect size: E.S -0.7). There were also small effects in a number of child (internalising symptoms, emotional behavioural disturbance and quality of life) and parent/caregiver (mental health, parenting stress and quality of life) outcomes; however, these did not remain significant when controlling for multiple comparisons. CONCLUSIONS: The sleeping sound ASD intervention is an efficacious and practical way to reduce sleep problems for autistic children. This brief behavioural intervention has the potential to be embedded easily into the Australian healthcare system. En ligne : http://dx.doi.org/10.1111/jcpp.13590 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490 [article] Sleeping Sound Autism Spectrum Disorder (ASD): a randomised controlled trial of a brief behavioural sleep intervention in primary school-aged autistic children [texte imprimé] / Nicole PAPADOPOULOS, Auteur ; Emma SCIBERRAS, Auteur ; Harriet HISCOCK, Auteur ; Katrina WILLIAMS, Auteur ; Jane MCGILLIVRAY, Auteur ; Cathrine MIHALOPOULOS, Auteur ; Lidia ENGEL, Auteur ; Matthew FULLER-TYSZKIEWICZ, Auteur ; Susannah T. BELLOWS, Auteur ; Deborah MARKS, Auteur ; Patricia HOWLIN, Auteur ; Nicole J. RINEHART, Auteur . - p.1423-1433. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-11 (November 2022) . - p.1423-1433 Mots-clés : Child  Humans  Child, Preschool  Adolescent  Autism Spectrum Disorder/complications/therapy/psychology  Quality of Life  Autistic Disorder/complications  Australia  Sleep  Sleep Wake Disorders/therapy/complications  Schools  Autism spectrum disorders  RCT design  intervention  treatment trial Index. décimale : PER Périodiques Résumé : BACKGROUND: Behavioural sleep problems are common in children with autism spectrum disorder (ASD); however, evidence for the efficacy of behavioural sleep interventions is limited. This study examined the efficacy of a brief behavioural sleep intervention in autistic children. It was hypothesised that the intervention would reduce overall child sleep problems (primary outcome), in addition to improvements in children's social, emotional, cognitive, academic functioning, and quality of life, and parent/caregivers' stress, quality of life, and mental health (secondary outcomes). METHODS: A randomised controlled trial was conducted with participants randomised via a computer-generated sequence to the sleeping sound intervention (n=123) or treatment as usual (n=122) group. Participants comprised 245 children with an ASD diagnosis. Inclusion criteria were as follows: confirmation of DSM IV or DSM-5 diagnosis of ASD, participants aged between 5 and 13 years and parent/caregiver report of moderate-severe sleep problems. Exclusion criteria were as follows: parent/caregiver intellectual disability or lacking sufficient English to complete questionnaires; and child participant with co-occurring medical conditions known to impact sleep. The intervention group received the sleeping sound intervention (2 × 50-min face-to-face sessions plus follow-up phone call) by a trained clinician. RESULTS: Change in children's sleep problems was measured by the Children's Sleep Habits Questionnaire (CSHQ) at 3 months post randomisation. Parents/caregivers of children in the intervention group reported a reduction in child sleep problems at 3 months post randomisation (effect size: E.S -0.7). There were also small effects in a number of child (internalising symptoms, emotional behavioural disturbance and quality of life) and parent/caregiver (mental health, parenting stress and quality of life) outcomes; however, these did not remain significant when controlling for multiple comparisons. CONCLUSIONS: The sleeping sound ASD intervention is an efficacious and practical way to reduce sleep problems for autistic children. This brief behavioural intervention has the potential to be embedded easily into the Australian healthcare system. En ligne : http://dx.doi.org/10.1111/jcpp.13590 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490

The population cost-effectiveness of a parenting intervention designed to prevent anxiety disorders in children / Cathrine MIHALOPOULOS in Journal of Child Psychology and Psychiatry, 56-9 (September 2015)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 56-9 (September 2015) . - p.1026-1033 Titre : The population cost-effectiveness of a parenting intervention designed to prevent anxiety disorders in children Type de document : texte imprimé Auteurs : Cathrine MIHALOPOULOS, Auteur ; Theo VOS, Auteur ; Ronald M. RAPEE, Auteur ; Jane PIRKIS, Auteur ; Mary Lou CHATTERTON, Auteur ; Yu-Chen LEE, Auteur ; Rob CARTER, Auteur Article en page(s) : p.1026-1033 Langues : Anglais (eng) Mots-clés : Economic evaluation  anxiety disorders  children  prevention Index. décimale : PER Périodiques Résumé : Background Prevention and early intervention for anxiety disorders has lagged behind many other forms of mental disorder. Recent research has demonstrated the efficacy of a parent-focussed psycho-educational programme. The programme is directed at parents of inhibited preschool children and has been shown to reduce anxiety disorders at 1 and 3 years following intervention. The current study assesses the cost-effectiveness of this intervention to determine whether it could provide value-for-money across a population. Method A cost-utility economic framework, using Disability-Adjusted-Life-Years (DALYs) as the outcome, was adopted. Economic modelling techniques were used to assess the incremental cost-effectiveness ratio (ICER) of the intervention within the Australian population context, which was modelled as add-on to current practice. The perspective was the health sector. Uncertainty was measured using multivariate probabilistic testing and key assumptions were tested using univariate sensitivity analysis. Results The median ICER for the intervention was AUD$8,000 per DALY averted with 99.8% of the uncertainty iterations falling below the threshold value-for-money criterion of AUD$50,000 per DALY averted. The results were robust to sensitivity testing. Conclusions Screening young children in a preschool setting for an inhibited temperament and providing a brief intervention to the parents of children with high levels of inhibition appears to provide very good value-for-money and worth considering in any package of preventive care. Further evaluation of this intervention under routine health service conditions will strengthen conclusions. Acceptability issues associated with this intervention, particularly to preschool staff and parents, need to be considered before wide-scale adoption is undertaken. En ligne : http://dx.doi.org/10.1111/jcpp.12438 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=267 [article] The population cost-effectiveness of a parenting intervention designed to prevent anxiety disorders in children [texte imprimé] / Cathrine MIHALOPOULOS, Auteur ; Theo VOS, Auteur ; Ronald M. RAPEE, Auteur ; Jane PIRKIS, Auteur ; Mary Lou CHATTERTON, Auteur ; Yu-Chen LEE, Auteur ; Rob CARTER, Auteur . - p.1026-1033. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 56-9 (September 2015) . - p.1026-1033 Mots-clés : Economic evaluation  anxiety disorders  children  prevention Index. décimale : PER Périodiques Résumé : Background Prevention and early intervention for anxiety disorders has lagged behind many other forms of mental disorder. Recent research has demonstrated the efficacy of a parent-focussed psycho-educational programme. The programme is directed at parents of inhibited preschool children and has been shown to reduce anxiety disorders at 1 and 3 years following intervention. The current study assesses the cost-effectiveness of this intervention to determine whether it could provide value-for-money across a population. Method A cost-utility economic framework, using Disability-Adjusted-Life-Years (DALYs) as the outcome, was adopted. Economic modelling techniques were used to assess the incremental cost-effectiveness ratio (ICER) of the intervention within the Australian population context, which was modelled as add-on to current practice. The perspective was the health sector. Uncertainty was measured using multivariate probabilistic testing and key assumptions were tested using univariate sensitivity analysis. Results The median ICER for the intervention was AUD$8,000 per DALY averted with 99.8% of the uncertainty iterations falling below the threshold value-for-money criterion of AUD$50,000 per DALY averted. The results were robust to sensitivity testing. Conclusions Screening young children in a preschool setting for an inhibited temperament and providing a brief intervention to the parents of children with high levels of inhibition appears to provide very good value-for-money and worth considering in any package of preventive care. Further evaluation of this intervention under routine health service conditions will strengthen conclusions. Acceptability issues associated with this intervention, particularly to preschool staff and parents, need to be considered before wide-scale adoption is undertaken. En ligne : http://dx.doi.org/10.1111/jcpp.12438 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=267

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