A Meta-analysis of Outcome Studies of Autistic Adults: Quantifying Effect Size, Quality, and Meta-regression / David MASON in Journal of Autism and Developmental Disorders, 51-9 (September 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-9 (September 2021) . - p.3165-3179 Titre : A Meta-analysis of Outcome Studies of Autistic Adults: Quantifying Effect Size, Quality, and Meta-regression Type de document : texte imprimé Auteurs : David MASON, Auteur ; Simone J. CAPP, Auteur ; Gavin R. STEWART, Auteur ; Matthew J. KEMPTON, Auteur ; Karen GLASER, Auteur ; Patricia HOWLIN, Auteur ; Francesca HAPPE, Auteur Article en page(s) : p.3165-3179 Langues : Anglais (eng) Mots-clés : Adult  Autism Spectrum Disorder  Autistic Disorder  Humans  Outcome Assessment, Health Care  Autism spectrum disorder  Functioning  Meta-analysis  Outcome Index. décimale : PER Périodiques Résumé : Longitudinal studies have generally reported poor outcomes in adulthood for the majority of individuals (c.50-60%) with autism. Several factors putatively predict outcome (e.g. IQ), but findings remain mixed. This paper presents an updated meta-analysis of autism outcome studies and extends previous findings with additional analyses (including meta-regression). A total of 4088 records was screened and 18 studies, involving 1199 individuals, were included in the quantitative analysis. Estimated percentages indicated that 20.0% of participants were rated as having a good outcome, 26.6% a fair outcome, and 49.3% a poor outcome. Meta-regression indicated that lower IQ in adulthood was predictive of poor outcome; other meta-regression models did not survive correction for multiple comparisons. Overall, outcomes for autistic people are on average poor, and higher IQ appears to be protective against having a poor outcome. The limitations of current constructs of outcome are discussed. En ligne : http://dx.doi.org/10.1007/s10803-020-04763-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453 [article] A Meta-analysis of Outcome Studies of Autistic Adults: Quantifying Effect Size, Quality, and Meta-regression [texte imprimé] / David MASON, Auteur ; Simone J. CAPP, Auteur ; Gavin R. STEWART, Auteur ; Matthew J. KEMPTON, Auteur ; Karen GLASER, Auteur ; Patricia HOWLIN, Auteur ; Francesca HAPPE, Auteur . - p.3165-3179. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-9 (September 2021) . - p.3165-3179 Mots-clés : Adult  Autism Spectrum Disorder  Autistic Disorder  Humans  Outcome Assessment, Health Care  Autism spectrum disorder  Functioning  Meta-analysis  Outcome Index. décimale : PER Périodiques Résumé : Longitudinal studies have generally reported poor outcomes in adulthood for the majority of individuals (c.50-60%) with autism. Several factors putatively predict outcome (e.g. IQ), but findings remain mixed. This paper presents an updated meta-analysis of autism outcome studies and extends previous findings with additional analyses (including meta-regression). A total of 4088 records was screened and 18 studies, involving 1199 individuals, were included in the quantitative analysis. Estimated percentages indicated that 20.0% of participants were rated as having a good outcome, 26.6% a fair outcome, and 49.3% a poor outcome. Meta-regression indicated that lower IQ in adulthood was predictive of poor outcome; other meta-regression models did not survive correction for multiple comparisons. Overall, outcomes for autistic people are on average poor, and higher IQ appears to be protective against having a poor outcome. The limitations of current constructs of outcome are discussed. En ligne : http://dx.doi.org/10.1007/s10803-020-04763-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453

Needs of Adolescents and Young Adults with Neurodevelopmental Disorders: Comparisons of Young People and Parent Perspectives / Hanna EKLUND in Journal of Autism and Developmental Disorders, 48-1 (January 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-1 (January 2018) . - p.83-91 Titre : Needs of Adolescents and Young Adults with Neurodevelopmental Disorders: Comparisons of Young People and Parent Perspectives Type de document : texte imprimé Auteurs : Hanna EKLUND, Auteur ; James L. FINDON, Auteur ; Tim CADMAN, Auteur ; Hannah HAYWARD, Auteur ; Dennis MURPHY, Auteur ; Philip ASHERSON, Auteur ; Karen GLASER, Auteur ; Kiriakos XENITIDIS, Auteur Article en page(s) : p.83-91 Langues : Anglais (eng) Mots-clés : Adhd  Asd  Needs assessment  Neurodevelopmental disorders  Young adulthood Index. décimale : PER Périodiques Résumé : This study used the Camberwell Assessment of Need for adults with Developmental and Intellectual Disabilities (CANDID) to examine the social, physical health and mental health needs of 168 young people (aged 14-24 years) with neurodevelopmental disorders and compared young person and parent ratings of need. Agreement was poor in 21 out of 25 domains. Parents consistently reported higher levels of need than young people in the majority of domains although young people with ADHD reported significantly more needs in physical health, eyesight/hearing, seizures, other mental health problems and safety of others than their parents. Both parent and young person perspectives of needs are necessary to ensure that needs that are predictive of current or future poor outcomes are not missed. En ligne : https://doi.org/10.1007/s10803-017-3295-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=336 [article] Needs of Adolescents and Young Adults with Neurodevelopmental Disorders: Comparisons of Young People and Parent Perspectives [texte imprimé] / Hanna EKLUND, Auteur ; James L. FINDON, Auteur ; Tim CADMAN, Auteur ; Hannah HAYWARD, Auteur ; Dennis MURPHY, Auteur ; Philip ASHERSON, Auteur ; Karen GLASER, Auteur ; Kiriakos XENITIDIS, Auteur . - p.83-91. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-1 (January 2018) . - p.83-91 Mots-clés : Adhd  Asd  Needs assessment  Neurodevelopmental disorders  Young adulthood Index. décimale : PER Périodiques Résumé : This study used the Camberwell Assessment of Need for adults with Developmental and Intellectual Disabilities (CANDID) to examine the social, physical health and mental health needs of 168 young people (aged 14-24 years) with neurodevelopmental disorders and compared young person and parent ratings of need. Agreement was poor in 21 out of 25 domains. Parents consistently reported higher levels of need than young people in the majority of domains although young people with ADHD reported significantly more needs in physical health, eyesight/hearing, seizures, other mental health problems and safety of others than their parents. Both parent and young person perspectives of needs are necessary to ensure that needs that are predictive of current or future poor outcomes are not missed. En ligne : https://doi.org/10.1007/s10803-017-3295-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=336

Obsessive-Compulsive Disorder in Adults with High-Functioning Autism Spectrum Disorder: What Does Self-Report with the OCI-R Tell Us? / Tim CADMAN in Autism Research, 8-5 (October 2015)  

Public ISBD [article]  inAutism Research > 8-5 (October 2015) . - p.477-485 Titre : Obsessive-Compulsive Disorder in Adults with High-Functioning Autism Spectrum Disorder: What Does Self-Report with the OCI-R Tell Us? Type de document : texte imprimé Auteurs : Tim CADMAN, Auteur ; Debbie SPAIN, Auteur ; Patrick JOHNSTON, Auteur ; Ailsa RUSSELL, Auteur ; David MATAIX-COLS, Auteur ; Michael C. CRAIG, Auteur ; Quinton DEELEY, Auteur ; Dene ROBERTSON, Auteur ; Clodagh M. MURPHY, Auteur ; Nicola GILLAN, Auteur ; C. Ellie WILSON, Auteur ; Maria MENDEZ, Auteur ; Christine ECKER, Auteur ; Eileen DALY, Auteur ; James L. FINDON, Auteur ; Karen GLASER, Auteur ; MRC AIMS CONSORTIUM, Auteur ; Francesca HAPPE, Auteur ; Declan G.M. MURPHY, Auteur Article en page(s) : p.477-485 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  adults  obsessive compulsive disorder  obsessive-compulsive inventory-revised  hoarding  self-report questionnaire Index. décimale : PER Périodiques Résumé : Little is known about the symptom profile of obsessive-compulsive disorder (OCD) in individuals who have autism spectrum disorders (ASD). It is also unknown whether self-report questionnaires are useful in measuring OCD in ASD. We sought to describe the symptom profiles of adults with ASD, OCD, and ASD + OCD using the Obsessive Compulsive Inventory-Revised (OCI-R), and to assess the utility of the OCI-R as a screening measure in a high-functioning adult ASD sample. Individuals with ASD (n = 171), OCD (n = 108), ASD + OCD (n = 54) and control participants (n = 92) completed the OCI-R. Individuals with ASD + OCD reported significantly higher levels of obsessive-compulsive symptoms than those with ASD alone. OCD symptoms were not significantly correlated with core ASD repetitive behaviors as measured on the ADI-R or ADOS-G. The OCI-R showed good psychometric properties and corresponded well with clinician diagnosis of OCD. Receiver operating characteristic analysis suggested cut-offs for OCI-R Total and Checking scores that discriminated well between ASD + versus –OCD, and fairly well between ASD-alone and OCD-alone. OCD manifests separately from ASD and is characterized by a different profile of repetitive thoughts and behaviors. The OCI-R appears to be useful as a screening tool in the ASD adult population. Autism Res 2015, 8: 477–485. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1461 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=270 [article] Obsessive-Compulsive Disorder in Adults with High-Functioning Autism Spectrum Disorder: What Does Self-Report with the OCI-R Tell Us? [texte imprimé] / Tim CADMAN, Auteur ; Debbie SPAIN, Auteur ; Patrick JOHNSTON, Auteur ; Ailsa RUSSELL, Auteur ; David MATAIX-COLS, Auteur ; Michael C. CRAIG, Auteur ; Quinton DEELEY, Auteur ; Dene ROBERTSON, Auteur ; Clodagh M. MURPHY, Auteur ; Nicola GILLAN, Auteur ; C. Ellie WILSON, Auteur ; Maria MENDEZ, Auteur ; Christine ECKER, Auteur ; Eileen DALY, Auteur ; James L. FINDON, Auteur ; Karen GLASER, Auteur ; MRC AIMS CONSORTIUM, Auteur ; Francesca HAPPE, Auteur ; Declan G.M. MURPHY, Auteur . - p.477-485. Langues : Anglais (eng) in Autism Research > 8-5 (October 2015) . - p.477-485 Mots-clés : autism spectrum disorder  adults  obsessive compulsive disorder  obsessive-compulsive inventory-revised  hoarding  self-report questionnaire Index. décimale : PER Périodiques Résumé : Little is known about the symptom profile of obsessive-compulsive disorder (OCD) in individuals who have autism spectrum disorders (ASD). It is also unknown whether self-report questionnaires are useful in measuring OCD in ASD. We sought to describe the symptom profiles of adults with ASD, OCD, and ASD + OCD using the Obsessive Compulsive Inventory-Revised (OCI-R), and to assess the utility of the OCI-R as a screening measure in a high-functioning adult ASD sample. Individuals with ASD (n = 171), OCD (n = 108), ASD + OCD (n = 54) and control participants (n = 92) completed the OCI-R. Individuals with ASD + OCD reported significantly higher levels of obsessive-compulsive symptoms than those with ASD alone. OCD symptoms were not significantly correlated with core ASD repetitive behaviors as measured on the ADI-R or ADOS-G. The OCI-R showed good psychometric properties and corresponded well with clinician diagnosis of OCD. Receiver operating characteristic analysis suggested cut-offs for OCI-R Total and Checking scores that discriminated well between ASD + versus –OCD, and fairly well between ASD-alone and OCD-alone. OCD manifests separately from ASD and is characterized by a different profile of repetitive thoughts and behaviors. The OCI-R appears to be useful as a screening tool in the ASD adult population. Autism Res 2015, 8: 477–485. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1461 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=270

Screening for co-occurring conditions in adults with autism spectrum disorder using the strengths and difficulties questionnaire: A pilot study / James L. FINDON in Autism Research, 9-12 (December 2016)  

Public ISBD [article]  inAutism Research > 9-12 (December 2016) . - p.1353-1363 Titre : Screening for co-occurring conditions in adults with autism spectrum disorder using the strengths and difficulties questionnaire: A pilot study Type de document : texte imprimé Auteurs : James L. FINDON, Auteur ; Tim CADMAN, Auteur ; Catherine S. STEWART, Auteur ; Emma WOODHOUSE, Auteur ; Hanna EKLUND, Auteur ; Hannah HAYWARD, Auteur ; Daniel DE LE HARPE GOLDEN, Auteur ; Eddie CHAPLIN, Auteur ; Karen GLASER, Auteur ; Emily SIMONOFF, Auteur ; Declan G.M. MURPHY, Auteur ; Patrick BOLTON, Auteur ; Fiona S. MCEWEN, Auteur Article en page(s) : p.1353-1363 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  co-occurring disorder  co-morbid disorder  hyperactivity  attention deficit hyperactivity disorder  anxiety  depression  obsessive–compulsive disorder Index. décimale : PER Périodiques Résumé : Adolescents and adults with autism spectrum disorder (ASD) are at elevated risk of co-occurring mental health problems. These are often undiagnosed, can cause significant impairment, and place a very high burden on family and carers. Detecting co-occurring disorders is extremely important. However, there is no validated screening tool for this purpose. The aim of this pilot study is to test the utility of the strengths and difficulties questionnaire (SDQ) to screen for co-occurring emotional disorders and hyperactivity in adolescents and adults with ASD. The SDQ was completed by 126 parents and 98 individuals with ASD (in 79 cases both parent and self-report were available from the same families). Inter-rater reliability, test-retest stability, internal consistency, and construct validity were examined. SDQ subscales were also compared to clinically utilized measures of emotional disorders and hyperactivity to establish the ability to predict risk of disorder. Inter-rater reliability (r = 0.42), test-retest stability (r = 0.64), internal consistency (α = 0.52–0.81) and construct validity (r = 0.42–0.57) for the SDQ subscales were comparable to general population samples. Parent- and self-report SDQ subscales were significantly associated with measures of anxiety, depression and hyperactivity (62–74% correctly classified). Parent-report performed significantly better than self-report; adults with ASD under-reported difficulties. The SDQ shows promise as a simple and efficient way to screen for emotional disorders and hyperactivity in adolescents and adults with ASD that could help reduce the impact of these disorders on individuals and their families. However, further more systematic attempts at validation are warranted. En ligne : http://dx.doi.org/10.1002/aur.1625 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298 [article] Screening for co-occurring conditions in adults with autism spectrum disorder using the strengths and difficulties questionnaire: A pilot study [texte imprimé] / James L. FINDON, Auteur ; Tim CADMAN, Auteur ; Catherine S. STEWART, Auteur ; Emma WOODHOUSE, Auteur ; Hanna EKLUND, Auteur ; Hannah HAYWARD, Auteur ; Daniel DE LE HARPE GOLDEN, Auteur ; Eddie CHAPLIN, Auteur ; Karen GLASER, Auteur ; Emily SIMONOFF, Auteur ; Declan G.M. MURPHY, Auteur ; Patrick BOLTON, Auteur ; Fiona S. MCEWEN, Auteur . - p.1353-1363. Langues : Anglais (eng) in Autism Research > 9-12 (December 2016) . - p.1353-1363 Mots-clés : autism spectrum disorder  co-occurring disorder  co-morbid disorder  hyperactivity  attention deficit hyperactivity disorder  anxiety  depression  obsessive–compulsive disorder Index. décimale : PER Périodiques Résumé : Adolescents and adults with autism spectrum disorder (ASD) are at elevated risk of co-occurring mental health problems. These are often undiagnosed, can cause significant impairment, and place a very high burden on family and carers. Detecting co-occurring disorders is extremely important. However, there is no validated screening tool for this purpose. The aim of this pilot study is to test the utility of the strengths and difficulties questionnaire (SDQ) to screen for co-occurring emotional disorders and hyperactivity in adolescents and adults with ASD. The SDQ was completed by 126 parents and 98 individuals with ASD (in 79 cases both parent and self-report were available from the same families). Inter-rater reliability, test-retest stability, internal consistency, and construct validity were examined. SDQ subscales were also compared to clinically utilized measures of emotional disorders and hyperactivity to establish the ability to predict risk of disorder. Inter-rater reliability (r = 0.42), test-retest stability (r = 0.64), internal consistency (α = 0.52–0.81) and construct validity (r = 0.42–0.57) for the SDQ subscales were comparable to general population samples. Parent- and self-report SDQ subscales were significantly associated with measures of anxiety, depression and hyperactivity (62–74% correctly classified). Parent-report performed significantly better than self-report; adults with ASD under-reported difficulties. The SDQ shows promise as a simple and efficient way to screen for emotional disorders and hyperactivity in adolescents and adults with ASD that could help reduce the impact of these disorders on individuals and their families. However, further more systematic attempts at validation are warranted. En ligne : http://dx.doi.org/10.1002/aur.1625 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298

Social anxiety in adult males with autism spectrum disorders / Debbie SPAIN in Research in Autism Spectrum Disorders, 32 (December 2016)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 32 (December 2016) . - p.13-23 Titre : Social anxiety in adult males with autism spectrum disorders Type de document : texte imprimé Auteurs : Debbie SPAIN, Auteur ; Francesca HAPPE, Auteur ; Patrick JOHNSTON, Auteur ; Malcolm CAMPBELL, Auteur ; Jacqueline SIN, Auteur ; Eileen DALY, Auteur ; Christine ECKER, Auteur ; Martin ANSON, Auteur ; Eddie CHAPLIN, Auteur ; Karen GLASER, Auteur ; M. Andreina MENDEZ, Auteur ; Karina LOVELL, Auteur ; Declan G.M. MURPHY, Auteur Article en page(s) : p.13-23 Langues : Anglais (eng) Mots-clés : Autism spectrum  Social anxiety  Social phobia  Adults  Self-report questionnaires Index. décimale : PER Périodiques Résumé : AbstractBackground Psychiatric conditions, notably anxiety, commonly co-occur with autism spectrum disorders (ASD). Method This study investigated self-reported behavioural, cognitive and affective symptoms of social anxiety (SA) in 50 adult males with ASD. Associations between SA, core ASD symptoms and facets of neuropsychological functioning were also examined. Results Twenty-six participants (52%) endorsed levels of SA that exceeded the suggested caseness threshold for social anxiety disorder. Categorical and dimensional data analyses indicated that there were no relationships between SA symptoms, present-state or childhood ASD symptom-severity, or measures of socio-emotional processing in this sample. Conclusions Study findings suggest that severity of SA is not merely a reflection of ASD symptom-severity. Further research is needed to ascertain the prevalence of SA in adult ASD epidemiological samples, and identify causal and maintaining mechanisms for these co-morbid symptoms. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.08.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=296 [article] Social anxiety in adult males with autism spectrum disorders [texte imprimé] / Debbie SPAIN, Auteur ; Francesca HAPPE, Auteur ; Patrick JOHNSTON, Auteur ; Malcolm CAMPBELL, Auteur ; Jacqueline SIN, Auteur ; Eileen DALY, Auteur ; Christine ECKER, Auteur ; Martin ANSON, Auteur ; Eddie CHAPLIN, Auteur ; Karen GLASER, Auteur ; M. Andreina MENDEZ, Auteur ; Karina LOVELL, Auteur ; Declan G.M. MURPHY, Auteur . - p.13-23. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 32 (December 2016) . - p.13-23 Mots-clés : Autism spectrum  Social anxiety  Social phobia  Adults  Self-report questionnaires Index. décimale : PER Périodiques Résumé : AbstractBackground Psychiatric conditions, notably anxiety, commonly co-occur with autism spectrum disorders (ASD). Method This study investigated self-reported behavioural, cognitive and affective symptoms of social anxiety (SA) in 50 adult males with ASD. Associations between SA, core ASD symptoms and facets of neuropsychological functioning were also examined. Results Twenty-six participants (52%) endorsed levels of SA that exceeded the suggested caseness threshold for social anxiety disorder. Categorical and dimensional data analyses indicated that there were no relationships between SA symptoms, present-state or childhood ASD symptom-severity, or measures of socio-emotional processing in this sample. Conclusions Study findings suggest that severity of SA is not merely a reflection of ASD symptom-severity. Further research is needed to ascertain the prevalence of SA in adult ASD epidemiological samples, and identify causal and maintaining mechanisms for these co-morbid symptoms. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.08.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=296

---

1 (1 - 5 / 5) Par page : 25 50 100 200