Sex differences in cortical volume and gyrification in autism / Marie SCHAER in Molecular Autism, (July 2015)  

Public ISBD [article]  inMolecular Autism > (July 2015) . - p.1-14 Titre : Sex differences in cortical volume and gyrification in autism Type de document : Texte imprimé et/ou numérique Auteurs : Marie SCHAER, Auteur ; John KOCHALKA, Auteur ; Aarthi PADMANABHAN, Auteur ; Kaustubh SUPEKAR, Auteur ; Vinod MENON, Auteur Article en page(s) : p.1-14 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Male predominance is a prominent feature of autism spectrum disorders (ASD), with a reported male to female ratio of 4:1. Because of the overwhelming focus on males, little is known about the neuroanatomical basis of sex differences in ASD. Investigations of sex differences with adequate sample sizes are critical for improving our understanding of the biological mechanisms underlying ASD in females. En ligne : http://dx.doi.org/10.1186/s13229-015-0035-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] Sex differences in cortical volume and gyrification in autism [Texte imprimé et/ou numérique] / Marie SCHAER, Auteur ; John KOCHALKA, Auteur ; Aarthi PADMANABHAN, Auteur ; Kaustubh SUPEKAR, Auteur ; Vinod MENON, Auteur . - p.1-14. Langues : Anglais (eng) in Molecular Autism > (July 2015) . - p.1-14 Index. décimale : PER Périodiques Résumé : Male predominance is a prominent feature of autism spectrum disorders (ASD), with a reported male to female ratio of 4:1. Because of the overwhelming focus on males, little is known about the neuroanatomical basis of sex differences in ASD. Investigations of sex differences with adequate sample sizes are critical for improving our understanding of the biological mechanisms underlying ASD in females. En ligne : http://dx.doi.org/10.1186/s13229-015-0035-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

Sex differences in structural organization of motor systems and their dissociable links with repetitive/restricted behaviors in children with autism / Kaustubh SUPEKAR in Molecular Autism, (September 2015)  

Public ISBD [article]  inMolecular Autism > (September 2015) . - p.1-13 Titre : Sex differences in structural organization of motor systems and their dissociable links with repetitive/restricted behaviors in children with autism Type de document : Texte imprimé et/ou numérique Auteurs : Kaustubh SUPEKAR, Auteur ; Vinod MENON, Auteur Article en page(s) : p.1-13 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is diagnosed much less often in females than males. Emerging behavioral accounts suggest that the clinical presentation of autism is different in females and males, yet research examining sex differences in core symptoms of autism in affected children has been limited. Additionally, to date, there have been no systematic attempts to characterize neuroanatomical differences underlying the distinct behavioral profiles observed in girls and boys with ASD. This is in part because extant ASD studies have included a small number of girls. En ligne : http://dx.doi.org/10.1186/s13229-015-0042-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] Sex differences in structural organization of motor systems and their dissociable links with repetitive/restricted behaviors in children with autism [Texte imprimé et/ou numérique] / Kaustubh SUPEKAR, Auteur ; Vinod MENON, Auteur . - p.1-13. Langues : Anglais (eng) in Molecular Autism > (September 2015) . - p.1-13 Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is diagnosed much less often in females than males. Emerging behavioral accounts suggest that the clinical presentation of autism is different in females and males, yet research examining sex differences in core symptoms of autism in affected children has been limited. Additionally, to date, there have been no systematic attempts to characterize neuroanatomical differences underlying the distinct behavioral profiles observed in girls and boys with ASD. This is in part because extant ASD studies have included a small number of girls. En ligne : http://dx.doi.org/10.1186/s13229-015-0042-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

The influence of sex and age on prevalence rates of comorbid conditions in autism / Kaustubh SUPEKAR in Autism Research, 10-5 (May 2017)  

Public ISBD [article]  inAutism Research > 10-5 (May 2017) . - p.778-789 Titre : The influence of sex and age on prevalence rates of comorbid conditions in autism Type de document : Texte imprimé et/ou numérique Auteurs : Kaustubh SUPEKAR, Auteur ; Tara IYER, Auteur ; Vinod MENON, Auteur Article en page(s) : p.778-789 Langues : Anglais (eng) Mots-clés : autism comorbidities  epilepsy  schizophrenia  age  sex Index. décimale : PER Périodiques Résumé : Individuals with ASD frequently experience one or more comorbid conditions. Here, we investigate the influence of sex and age—two important, yet understudied factors—on ten common comorbid conditions in ASD, using cross-sectional data from 4790 individuals with ASD and 1,842,575 individuals without ASD. Epilepsy, ADHD, and CNS/cranial anomalies showed exceptionally large proportions in both male (>19%) and female (>15%), children/adolescents with ASD. Notably, these prevalence rates decreased drastically with age in both males and females. In contrast, the prevalence of schizophrenia increased with age affecting a disproportionately large number of older (?35 year) adult males (25%), compared to females (7.7%), with ASD. Bowel disorders showed a complex U-pattern accompanied by changes in sex disparity with age. These results highlight crucial differences between cross-sectional comorbidity patterns and their interactions with sex and age, which may aid in the development of effective sex- and age-specific diagnostic/treatment strategies for ASD and comorbid conditions. En ligne : http://dx.doi.org/10.1002/aur.1741 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=307 [article] The influence of sex and age on prevalence rates of comorbid conditions in autism [Texte imprimé et/ou numérique] / Kaustubh SUPEKAR, Auteur ; Tara IYER, Auteur ; Vinod MENON, Auteur . - p.778-789. Langues : Anglais (eng) in Autism Research > 10-5 (May 2017) . - p.778-789 Mots-clés : autism comorbidities  epilepsy  schizophrenia  age  sex Index. décimale : PER Périodiques Résumé : Individuals with ASD frequently experience one or more comorbid conditions. Here, we investigate the influence of sex and age—two important, yet understudied factors—on ten common comorbid conditions in ASD, using cross-sectional data from 4790 individuals with ASD and 1,842,575 individuals without ASD. Epilepsy, ADHD, and CNS/cranial anomalies showed exceptionally large proportions in both male (>19%) and female (>15%), children/adolescents with ASD. Notably, these prevalence rates decreased drastically with age in both males and females. In contrast, the prevalence of schizophrenia increased with age affecting a disproportionately large number of older (?35 year) adult males (25%), compared to females (7.7%), with ASD. Bowel disorders showed a complex U-pattern accompanied by changes in sex disparity with age. These results highlight crucial differences between cross-sectional comorbidity patterns and their interactions with sex and age, which may aid in the development of effective sex- and age-specific diagnostic/treatment strategies for ASD and comorbid conditions. En ligne : http://dx.doi.org/10.1002/aur.1741 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=307

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