Homogeneous Subgroups of Young Children with Autism Improve Phenotypic Characterization in the Study to Explore Early Development / Lisa D. WIGGINS in Journal of Autism and Developmental Disorders, 47-11 (November 2017)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 47-11 (November 2017) . - p.3634-3645 Titre : Homogeneous Subgroups of Young Children with Autism Improve Phenotypic Characterization in the Study to Explore Early Development Type de document : Texte imprimé et/ou numérique Auteurs : Lisa D. WIGGINS, Auteur ; L. H. TIAN, Auteur ; S. E. LEVY, Auteur ; C. RICE, Auteur ; L. C. LEE, Auteur ; Laura A. SCHIEVE, Auteur ; J. PANDEY, Auteur ; J. DANIELS, Auteur ; Lisa BLASKEY, Auteur ; S. HEPBURN, Auteur ; R. LANDA, Auteur ; R. EDMONDSON-PRETZEL, Auteur ; W. THOMPSON, Auteur Article en page(s) : p.3634-3645 Langues : Anglais (eng) Mots-clés : Autism  Autism spectrum disorder  Characterization  Phenotypes  Subgroups Index. décimale : PER Périodiques Résumé : The objective of this study was to identify homogenous classes of young children with autism spectrum disorder (ASD) to improve phenotypic characterization. Children were enrolled in the Study to Explore Early Development between 2 and 5 years of age. 707 children were classified with ASD after a comprehensive evaluation with strict diagnostic algorithms. Four classes of children with ASD were identified from latent class analysis: mild language delay with cognitive rigidity, mild language and motor delay with dysregulation, general developmental delay, and significant developmental delay with repetitive motor behaviors. We conclude that a four-class phenotypic model of children with ASD best describes our data and improves phenotypic characterization of young children with ASD. Implications for screening, diagnosis, and research are discussed. En ligne : http://dx.doi.org/10.1007/s10803-017-3280-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=325 [article] Homogeneous Subgroups of Young Children with Autism Improve Phenotypic Characterization in the Study to Explore Early Development [Texte imprimé et/ou numérique] / Lisa D. WIGGINS, Auteur ; L. H. TIAN, Auteur ; S. E. LEVY, Auteur ; C. RICE, Auteur ; L. C. LEE, Auteur ; Laura A. SCHIEVE, Auteur ; J. PANDEY, Auteur ; J. DANIELS, Auteur ; Lisa BLASKEY, Auteur ; S. HEPBURN, Auteur ; R. LANDA, Auteur ; R. EDMONDSON-PRETZEL, Auteur ; W. THOMPSON, Auteur . - p.3634-3645. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 47-11 (November 2017) . - p.3634-3645 Mots-clés : Autism  Autism spectrum disorder  Characterization  Phenotypes  Subgroups Index. décimale : PER Périodiques Résumé : The objective of this study was to identify homogenous classes of young children with autism spectrum disorder (ASD) to improve phenotypic characterization. Children were enrolled in the Study to Explore Early Development between 2 and 5 years of age. 707 children were classified with ASD after a comprehensive evaluation with strict diagnostic algorithms. Four classes of children with ASD were identified from latent class analysis: mild language delay with cognitive rigidity, mild language and motor delay with dysregulation, general developmental delay, and significant developmental delay with repetitive motor behaviors. We conclude that a four-class phenotypic model of children with ASD best describes our data and improves phenotypic characterization of young children with ASD. Implications for screening, diagnosis, and research are discussed. En ligne : http://dx.doi.org/10.1007/s10803-017-3280-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=325

Neuromagnetic Beta-Band Oscillations during Motor Imitation in Youth with Autism / I. BUARD in Autism Research and Treatment, 2018 (2018)  

Public ISBD [article]  inAutism Research and Treatment > 2018 (2018) . - 12p. Titre : Neuromagnetic Beta-Band Oscillations during Motor Imitation in Youth with Autism Type de document : Texte imprimé et/ou numérique Auteurs : I. BUARD, Auteur ; E. KRONBERG, Auteur ; S. STEINMETZ, Auteur ; S. HEPBURN, Auteur ; D. C. ROJAS, Auteur Article en page(s) : 12p. Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Children with ASD often exhibit early difficulties with action imitation, possibly due to low-level sensory or motor impairments. Impaired cortical rhythms have been demonstrated in adults with ASD during motor imitation. While those oscillations reflect an age-dependent process, they have not been fully investigated in youth with ASD. We collected magnetoencephalography data to examine patterns of oscillatory activity in the mu (8-13 Hz) and beta frequency (15-30 Hz) range in 14 adolescents with and 14 adolescents without ASD during a fine motor imitation task. Typically developing adolescents exhibited adult-like patterns of motor signals, e.g., event-related beta and mu desynchronization (ERD) before and during the movement and a postmovement beta rebound (PMBR) after the movement. In contrast, those with ASD exhibited stronger beta and mu-ERD and reduced PMBR. Behavioral performance was similar between groups despite differences in motor cortical oscillations. Finally, we observed age-related increases in PBMR and beta-ERD in the typically developing children, but this correlation was not present in the autism group. These results suggest reduced inhibitory drive in cortical rhythms in youth with autism during intact motor imitation. Furthermore, impairments in motor brain signals in autism may not be due to delayed brain development. In the context of the excitation-inhibition imbalance perspectives of autism, we offer new insights into altered organization of neurophysiological networks. En ligne : http://dx.doi.org/10.1155/2018/9035793 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402 [article] Neuromagnetic Beta-Band Oscillations during Motor Imitation in Youth with Autism [Texte imprimé et/ou numérique] / I. BUARD, Auteur ; E. KRONBERG, Auteur ; S. STEINMETZ, Auteur ; S. HEPBURN, Auteur ; D. C. ROJAS, Auteur . - 12p. Langues : Anglais (eng) in Autism Research and Treatment > 2018 (2018) . - 12p. Index. décimale : PER Périodiques Résumé : Children with ASD often exhibit early difficulties with action imitation, possibly due to low-level sensory or motor impairments. Impaired cortical rhythms have been demonstrated in adults with ASD during motor imitation. While those oscillations reflect an age-dependent process, they have not been fully investigated in youth with ASD. We collected magnetoencephalography data to examine patterns of oscillatory activity in the mu (8-13 Hz) and beta frequency (15-30 Hz) range in 14 adolescents with and 14 adolescents without ASD during a fine motor imitation task. Typically developing adolescents exhibited adult-like patterns of motor signals, e.g., event-related beta and mu desynchronization (ERD) before and during the movement and a postmovement beta rebound (PMBR) after the movement. In contrast, those with ASD exhibited stronger beta and mu-ERD and reduced PMBR. Behavioral performance was similar between groups despite differences in motor cortical oscillations. Finally, we observed age-related increases in PBMR and beta-ERD in the typically developing children, but this correlation was not present in the autism group. These results suggest reduced inhibitory drive in cortical rhythms in youth with autism during intact motor imitation. Furthermore, impairments in motor brain signals in autism may not be due to delayed brain development. In the context of the excitation-inhibition imbalance perspectives of autism, we offer new insights into altered organization of neurophysiological networks. En ligne : http://dx.doi.org/10.1155/2018/9035793 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402

Temperament Similarities and Differences: A Comparison of Factor Structures from the Behavioral Style Questionnaire in Children with and Without Autism Spectrum Disorder / Brian D. BARGER in Journal of Autism and Developmental Disorders, 49-5 (May 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-5 (May 2019) . - p.1749-1762 Titre : Temperament Similarities and Differences: A Comparison of Factor Structures from the Behavioral Style Questionnaire in Children with and Without Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Brian D. BARGER, Auteur ; E. J. MOODY, Auteur ; C. LEDBETTER, Auteur ; L. D'ABREU, Auteur ; S. HEPBURN, Auteur ; S. A. ROSENBERG, Auteur Article en page(s) : p.1749-1762 Langues : Anglais (eng) Mots-clés : Autism  Developmental disabilities  Factor structure  Temperament Index. décimale : PER Périodiques Résumé : The majority of studies of temperament in children with autism spectrum disorder (ASD) use scales normed on typical populations. The present study examined a widely used measure of temperament, the Behavioral Style Questionnaire (McDevitt and Carey in Behavioral Styles Questionnaire, Behavioral-Developmental Initiatives Scottsdale, AZ, 1975) to determine whether it contains the temperament traits theorized by its creators. Neither confirmatory nor exploratory factor analysis, using a sample of children with ASD and a population comparison group, identified the theorized nine temperament factors; many items did not strongly load on any of the original factors. A 10 factor solution best described the ASD data and a 9 factor solution best described the typical group's data. There were substantial similarities in the 9 factor solutions, but groups differed from one another enough to question construct similarity for several factors. These results highlight that more basic psychometric research is needed to better understand the BSQ in children with ASD. En ligne : http://dx.doi.org/10.1007/s10803-018-03866-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=393 [article] Temperament Similarities and Differences: A Comparison of Factor Structures from the Behavioral Style Questionnaire in Children with and Without Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Brian D. BARGER, Auteur ; E. J. MOODY, Auteur ; C. LEDBETTER, Auteur ; L. D'ABREU, Auteur ; S. HEPBURN, Auteur ; S. A. ROSENBERG, Auteur . - p.1749-1762. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-5 (May 2019) . - p.1749-1762 Mots-clés : Autism  Developmental disabilities  Factor structure  Temperament Index. décimale : PER Périodiques Résumé : The majority of studies of temperament in children with autism spectrum disorder (ASD) use scales normed on typical populations. The present study examined a widely used measure of temperament, the Behavioral Style Questionnaire (McDevitt and Carey in Behavioral Styles Questionnaire, Behavioral-Developmental Initiatives Scottsdale, AZ, 1975) to determine whether it contains the temperament traits theorized by its creators. Neither confirmatory nor exploratory factor analysis, using a sample of children with ASD and a population comparison group, identified the theorized nine temperament factors; many items did not strongly load on any of the original factors. A 10 factor solution best described the ASD data and a 9 factor solution best described the typical group's data. There were substantial similarities in the 9 factor solutions, but groups differed from one another enough to question construct similarity for several factors. These results highlight that more basic psychometric research is needed to better understand the BSQ in children with ASD. En ligne : http://dx.doi.org/10.1007/s10803-018-03866-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=393

---

1 (1 - 3 / 3)