Commentary: sex difference differences? A reply to Constantino / D. S. MESSINGER in Molecular Autism, 7 (2016)  

Public ISBD [article]  inMolecular Autism > 7 (2016) . - 31p. Titre : Commentary: sex difference differences? A reply to Constantino Type de document : Texte imprimé et/ou numérique Auteurs : D. S. MESSINGER, Auteur ; Gregory S. YOUNG, Auteur ; S. J. WEBB, Auteur ; S. OZONOFF, Auteur ; Susan E. BRYSON, Auteur ; Alice S. CARTER, Auteur ; Leslie J. CARVER, Auteur ; Tony CHARMAN, Auteur ; Katarzyna CHAWARSKA, Auteur ; S. CURTIN, Auteur ; K. DOBKINS, Auteur ; I. HERTZ-PICCIOTTO, Auteur ; T. HUTMAN, Auteur ; J. M. IVERSON, Auteur ; R. LANDA, Auteur ; C. A. NELSON, Auteur ; W. L. STONE, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Lonnie ZWAIGENBAUM, Auteur Article en page(s) : 31p. Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Female protective effect  High-risk siblings  Sex differences Index. décimale : PER Périodiques Résumé : Messinger et al. found a 3.18 odds ratio of male to female ASD recurrence in 1241 prospectively followed high-risk (HR) siblings. Among high-risk siblings (with and without ASD), as well as among 583 low-risk controls, girls exhibited higher performance on the Mullen Scales of Early Learning, as well as lower restricted and repetitive behavior severity scores on the Autism Diagnostic Observation Schedule (ADOS) than boys. That is, female-favoring sex differences in developmental performance and autism traits were evident among low-risk and non-ASD high-risk children, as well as those with ASD. Constantino (Mol Autism) suggests that sex differences in categorical ASD outcomes in Messinger et al. should be understood as a female protective effect. We are receptive to Constantino's (Mol Autism) suggestion, and propose that quantitative sex differences in autism-related features are keys to understanding this female protective effect. En ligne : http://dx.doi.org/10.1186/s13229-016-0093-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=328 [article] Commentary: sex difference differences? A reply to Constantino [Texte imprimé et/ou numérique] / D. S. MESSINGER, Auteur ; Gregory S. YOUNG, Auteur ; S. J. WEBB, Auteur ; S. OZONOFF, Auteur ; Susan E. BRYSON, Auteur ; Alice S. CARTER, Auteur ; Leslie J. CARVER, Auteur ; Tony CHARMAN, Auteur ; Katarzyna CHAWARSKA, Auteur ; S. CURTIN, Auteur ; K. DOBKINS, Auteur ; I. HERTZ-PICCIOTTO, Auteur ; T. HUTMAN, Auteur ; J. M. IVERSON, Auteur ; R. LANDA, Auteur ; C. A. NELSON, Auteur ; W. L. STONE, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Lonnie ZWAIGENBAUM, Auteur . - 31p. Langues : Anglais (eng) in Molecular Autism > 7 (2016) . - 31p. Mots-clés : Autism spectrum disorder  Female protective effect  High-risk siblings  Sex differences Index. décimale : PER Périodiques Résumé : Messinger et al. found a 3.18 odds ratio of male to female ASD recurrence in 1241 prospectively followed high-risk (HR) siblings. Among high-risk siblings (with and without ASD), as well as among 583 low-risk controls, girls exhibited higher performance on the Mullen Scales of Early Learning, as well as lower restricted and repetitive behavior severity scores on the Autism Diagnostic Observation Schedule (ADOS) than boys. That is, female-favoring sex differences in developmental performance and autism traits were evident among low-risk and non-ASD high-risk children, as well as those with ASD. Constantino (Mol Autism) suggests that sex differences in categorical ASD outcomes in Messinger et al. should be understood as a female protective effect. We are receptive to Constantino's (Mol Autism) suggestion, and propose that quantitative sex differences in autism-related features are keys to understanding this female protective effect. En ligne : http://dx.doi.org/10.1186/s13229-016-0093-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=328

Shifting Preferences for Primate Faces in Neurotypical Infants and Infants Later Diagnosed With ASD / A. YAMASHIRO in Autism Research, 12-2 (February 2019)  

Public ISBD [article]  inAutism Research > 12-2 (February 2019) . - p.249-262 Titre : Shifting Preferences for Primate Faces in Neurotypical Infants and Infants Later Diagnosed With ASD Type de document : Texte imprimé et/ou numérique Auteurs : A. YAMASHIRO, Auteur ; A. SORCINELLI, Auteur ; T. RAHMAN, Auteur ; R. ELBOGEN, Auteur ; S. CURTIN, Auteur ; A. VOULOUMANOS, Auteur Article en page(s) : p.249-262 Langues : Anglais (eng) Mots-clés : Face preference  autism spectrum disorder  eye tracking  human faces  infancy  monkey faces Index. décimale : PER Périodiques Résumé : Infants look at others' faces to gather social information. Newborns look equally at human and monkey faces but prefer human faces by 1 month, helping them learn to communicate and interact with others. Infants later diagnosed with autism spectrum disorder (ASD) look at human faces less than neurotypical infants, which may underlie some deficits in social-communication later in life. Here, we asked whether infants later diagnosed with ASD differ in their preferences for both human and nonhuman primate faces compared to neurotypical infants over their first 2 years of life. We compare infants' relative looking times to human or monkey faces paired with nonface controls (Experiment 1) and infants' total looking times to pairs of human and monkey faces (Experiment 2). Across two experiments, we find that between 6 and 18 months, infants later diagnosed with ASD show a greater downturn (decrease after an initial increase) in looking at both primate faces than neurotypical infants. A decrease in attention to primate faces may partly underlie the social-communicative difficulties in children with ASD and could reveal how early perceptual experiences with faces affect development. Autism Res 2019, 12: 249-262 (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Looking at faces helps infants learn to interact with others. Infants look equally at human and monkey faces at birth but prefer human faces by 1 month. Infants later diagnosed with ASD who show deficits in social-communication look at human faces less than neurotypical infants. We find that a downturn (decline after an initial increase) in attention to both human and monkey faces between 6 and 18 months may partly underlie the social-communicative difficulties in children with ASD. En ligne : http://dx.doi.org/10.1002/aur.2043 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=383 [article] Shifting Preferences for Primate Faces in Neurotypical Infants and Infants Later Diagnosed With ASD [Texte imprimé et/ou numérique] / A. YAMASHIRO, Auteur ; A. SORCINELLI, Auteur ; T. RAHMAN, Auteur ; R. ELBOGEN, Auteur ; S. CURTIN, Auteur ; A. VOULOUMANOS, Auteur . - p.249-262. Langues : Anglais (eng) in Autism Research > 12-2 (February 2019) . - p.249-262 Mots-clés : Face preference  autism spectrum disorder  eye tracking  human faces  infancy  monkey faces Index. décimale : PER Périodiques Résumé : Infants look at others' faces to gather social information. Newborns look equally at human and monkey faces but prefer human faces by 1 month, helping them learn to communicate and interact with others. Infants later diagnosed with autism spectrum disorder (ASD) look at human faces less than neurotypical infants, which may underlie some deficits in social-communication later in life. Here, we asked whether infants later diagnosed with ASD differ in their preferences for both human and nonhuman primate faces compared to neurotypical infants over their first 2 years of life. We compare infants' relative looking times to human or monkey faces paired with nonface controls (Experiment 1) and infants' total looking times to pairs of human and monkey faces (Experiment 2). Across two experiments, we find that between 6 and 18 months, infants later diagnosed with ASD show a greater downturn (decrease after an initial increase) in looking at both primate faces than neurotypical infants. A decrease in attention to primate faces may partly underlie the social-communicative difficulties in children with ASD and could reveal how early perceptual experiences with faces affect development. Autism Res 2019, 12: 249-262 (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Looking at faces helps infants learn to interact with others. Infants look equally at human and monkey faces at birth but prefer human faces by 1 month. Infants later diagnosed with ASD who show deficits in social-communication look at human faces less than neurotypical infants. We find that a downturn (decline after an initial increase) in attention to both human and monkey faces between 6 and 18 months may partly underlie the social-communicative difficulties in children with ASD. En ligne : http://dx.doi.org/10.1002/aur.2043 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=383

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