[article]
Titre : |
A Meta-analysis of Gut Microbiota in Children with Autism |
Type de document : |
Texte imprimé et/ou numérique |
Auteurs : |
P. ANDREO-MARTÍNEZ, Auteur ; M. RUBIO-APARICIO, Auteur ; J. SÁNCHEZ-MECA, Auteur ; A. VEAS, Auteur ; A. E. MARTINEZ-GONZALEZ, Auteur |
Article en page(s) : |
p.1374-1387 |
Langues : |
Anglais (eng) |
Mots-clés : |
Autism Spectrum Disorder/microbiology Autistic Disorder Bacteria Child Dysbiosis/microbiology Gastrointestinal Microbiome Humans Autism spectrum disorders (ASD) Gut microbiota Meta-analysis Microbiota-gut-brain axis Systematic review |
Index. décimale : |
PER Périodiques |
Résumé : |
Previous studies have reported dysbiosis in the gut microbiota (GM) of children with autism spectrum disorders (ASD), which may be a determining factor on child development through the microbiota-gut-brain axis. However, it is not clear if there is a specific group of dysbiotic bacteria in ASD. The aim of this study was to carry out a meta-analysis on the studies that analyze GM in children with ASD. 18 studies fulfilled our selection criteria. Our results showed a lower relative abundance of Streptococcus (SMD(+)?=?- 0.999; 95% CI - 1.549, - 0.449) and Bifidobacterium genera (SMD(+)?=?- 0.513; 95% CI - 0.953, - 0.073) in children with ASD. Overall, the Bifidobacterium genera is involved. However, differences found between studies are attributed to factors such as reporting bias. |
En ligne : |
http://dx.doi.org/10.1007/s10803-021-05002-y |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455 |
in Journal of Autism and Developmental Disorders > 52-3 (March 2022) . - p.1374-1387
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