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Group cognitive behaviour therapy (CBT) for social interaction anxiety in adults with autism spectrum disorders (ASD) / Debbie SPAIN in Research in Autism Spectrum Disorders, 41-42 (September 2017)
[article]
Titre : Group cognitive behaviour therapy (CBT) for social interaction anxiety in adults with autism spectrum disorders (ASD) Type de document : Texte imprimé et/ou numérique Auteurs : Debbie SPAIN, Auteur ; Sarah H. BLAINEY, Auteur ; Kyla VAILLANCOURT, Auteur Article en page(s) : p.20-30 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders (ASD) Asperger syndrome Adults Social anxiety Social skills Group cognitive behaviour therapy (CBT) Index. décimale : PER Périodiques Résumé : Group social skills interventions (SSI) are partially effective for addressing the communication and social interaction impairments experienced by individuals with autism spectrum disorders (ASD). Social anxiety has been found to be a moderating mechanism for SSI in young people with ASD. Comparatively few studies have investigated the effectiveness of SSI in the adult ASD population, and none so far have investigated group approaches incorporating SSI and anxiety management techniques. Method The present study describes the design and evaluation of a non-randomised single-arm, 11 week group interaction anxiety and social skills intervention, piloted on three occasions during routine clinical practice at an adult ASD service. The intervention was informed by a cognitive behaviour therapy (CBT) framework. Eighteen cognitively-able adult males with ASD attended. Outcome measures were completed pre- and post-intervention. Results Self-reported social anxiety improved (p = 0.01, d = 0.65). Low mood, general anxiety and functioning did not change significantly (p > 0.05, d < 0.20). Qualitative feedback indicated that participants found the intervention to be acceptable and useful for improving social knowledge and coping strategies, and reducing avoidance behaviours. Attrition was low (n = 2). Conclusions These results suggest that integrating SSI and anxiety management techniques in a group format is acceptable to adults with ASD, and can reduce symptoms of social anxiety. Whether SSI enhance social skills in adults requires further investigation. In clinical practice, consideration should be given to augmenting SSI with CBT techniques designed to target concurrent symptoms of social anxiety. En ligne : https://doi.org/10.1016/j.rasd.2017.07.005 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=321
in Research in Autism Spectrum Disorders > 41-42 (September 2017) . - p.20-30[article] Group cognitive behaviour therapy (CBT) for social interaction anxiety in adults with autism spectrum disorders (ASD) [Texte imprimé et/ou numérique] / Debbie SPAIN, Auteur ; Sarah H. BLAINEY, Auteur ; Kyla VAILLANCOURT, Auteur . - p.20-30.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 41-42 (September 2017) . - p.20-30
Mots-clés : Autism spectrum disorders (ASD) Asperger syndrome Adults Social anxiety Social skills Group cognitive behaviour therapy (CBT) Index. décimale : PER Périodiques Résumé : Group social skills interventions (SSI) are partially effective for addressing the communication and social interaction impairments experienced by individuals with autism spectrum disorders (ASD). Social anxiety has been found to be a moderating mechanism for SSI in young people with ASD. Comparatively few studies have investigated the effectiveness of SSI in the adult ASD population, and none so far have investigated group approaches incorporating SSI and anxiety management techniques. Method The present study describes the design and evaluation of a non-randomised single-arm, 11 week group interaction anxiety and social skills intervention, piloted on three occasions during routine clinical practice at an adult ASD service. The intervention was informed by a cognitive behaviour therapy (CBT) framework. Eighteen cognitively-able adult males with ASD attended. Outcome measures were completed pre- and post-intervention. Results Self-reported social anxiety improved (p = 0.01, d = 0.65). Low mood, general anxiety and functioning did not change significantly (p > 0.05, d < 0.20). Qualitative feedback indicated that participants found the intervention to be acceptable and useful for improving social knowledge and coping strategies, and reducing avoidance behaviours. Attrition was low (n = 2). Conclusions These results suggest that integrating SSI and anxiety management techniques in a group format is acceptable to adults with ASD, and can reduce symptoms of social anxiety. Whether SSI enhance social skills in adults requires further investigation. In clinical practice, consideration should be given to augmenting SSI with CBT techniques designed to target concurrent symptoms of social anxiety. En ligne : https://doi.org/10.1016/j.rasd.2017.07.005 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=321 Association of Autism Spectrum Disorders and Inflammatory Bowel Disease / M. LEE in Journal of Autism and Developmental Disorders, 48-5 (May 2018)
[article]
Titre : Association of Autism Spectrum Disorders and Inflammatory Bowel Disease Type de document : Texte imprimé et/ou numérique Auteurs : M. LEE, Auteur ; J. KRISHNAMURTHY, Auteur ; A. SUSI, Auteur ; C. SULLIVAN, Auteur ; G. H. GORMAN, Auteur ; E. HISLE-GORMAN, Auteur ; C. R. ERDIE-LALENA, Auteur ; C. M. NYLUND, Auteur Article en page(s) : p.1523-1529 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders (ASD) Crohn's disease (CD) Inflammatory bowel disease (IBD) Ulcerative colitis (UC) Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) and inflammatory bowel disease (IBD) both have multifactorial pathogenesis with an increasing number of studies demonstrating gut-brain associations. We aim to examine the association between ASD and IBD using strict classification criteria for IBD. We conducted a retrospective case-cohort study using records from the Military Health System database with IBD defined as having one encounter with an ICD-9-CM diagnostic code for IBD and at least one outpatient prescription dispensed for a medication to treat IBD. Children with ASD were more likely to meet criteria for Crohn's disease (CD) and Ulcerative colitis (UC) compared to controls. This higher prevalence of CD and UC in children with ASD compared to controls confirms the association of ASD with IBD. En ligne : http://dx.doi.org/10.1007/s10803-017-3409-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=355
in Journal of Autism and Developmental Disorders > 48-5 (May 2018) . - p.1523-1529[article] Association of Autism Spectrum Disorders and Inflammatory Bowel Disease [Texte imprimé et/ou numérique] / M. LEE, Auteur ; J. KRISHNAMURTHY, Auteur ; A. SUSI, Auteur ; C. SULLIVAN, Auteur ; G. H. GORMAN, Auteur ; E. HISLE-GORMAN, Auteur ; C. R. ERDIE-LALENA, Auteur ; C. M. NYLUND, Auteur . - p.1523-1529.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 48-5 (May 2018) . - p.1523-1529
Mots-clés : Autism spectrum disorders (ASD) Crohn's disease (CD) Inflammatory bowel disease (IBD) Ulcerative colitis (UC) Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) and inflammatory bowel disease (IBD) both have multifactorial pathogenesis with an increasing number of studies demonstrating gut-brain associations. We aim to examine the association between ASD and IBD using strict classification criteria for IBD. We conducted a retrospective case-cohort study using records from the Military Health System database with IBD defined as having one encounter with an ICD-9-CM diagnostic code for IBD and at least one outpatient prescription dispensed for a medication to treat IBD. Children with ASD were more likely to meet criteria for Crohn's disease (CD) and Ulcerative colitis (UC) compared to controls. This higher prevalence of CD and UC in children with ASD compared to controls confirms the association of ASD with IBD. En ligne : http://dx.doi.org/10.1007/s10803-017-3409-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=355 Associations of endocrine stress-related gene polymorphisms with risk of autism spectrum disorders: Evidence from an integrated meta-analysis / Ping-yuan YANG in Autism Research, 10-11 (November 2017)
[article]
Titre : Associations of endocrine stress-related gene polymorphisms with risk of autism spectrum disorders: Evidence from an integrated meta-analysis Type de document : Texte imprimé et/ou numérique Auteurs : Ping-yuan YANG, Auteur ; Ya-jing MENGA, Auteur ; Tao LI, Auteur ; Yi HUANG, Auteur Article en page(s) : p.1722-1736 Langues : Anglais (eng) Mots-clés : autism spectrum disorders (ASD) catechol-O-methyl transferase (COMT) serotonin transporter stress response Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) are related to serotonin transporter (5-HTT) and catechol-O-methyl transferase (COMT) as two most monoaminergic polymorphic variations. However, multiple studies assessing rs4680 and 5-HTTLPR variants in ASD have reported inconsistent results. Therefore, we conducted an integrated meta-analysis to combine case-control and transmission/disequilibrium test (TDT) studies to determine whether COMT and 5-HTT are associated with ASD. We searched multiple electronic databases (PubMed, EmBase and Web of Science) to identify studies assessing the rs4680 and 5-HTTLPR variants in ASD from Jan 1997 to Dec 2016. Then allelic data from case–control and TDT studies were analyzed by the Catmap package in the R software. A total of 5 studies were eligible for the meta-analysis of rs4680, including 3 case–control, 1 TDT and 1 TDT & case–control studies. Meanwhile, 22 studies of 5-HTTLPR were available, including 16 TDT, 4 case–control and 2 TDT & case–control studies. The current meta-analysis included 814 ASD cases, 741 controls and 311 families related to rs4680; 749 ASD cases, 1,118 controls and 1,861 families relevant to 5-HTTLPR were also evaluated. For rs4680, the pooled OR was 1.18 (95% CI?=?0.87–1.59, P?=?0.29, Pheterogeneity?0.00001). There was no significant association of rs4680 with risk of ASD between the two subgroups. For 5-HTTLPR, the pooled OR was 1.05 (95% CI?=?0.92–1.20, P?=?0.4652, Pheterogeneity?0.00001). Meanwhile, we found no significant risk in individual case–control or TDT studies. The above findings indicated that neither COMT rs4680 nor 5-HTT 5-HTTLPR polymorphism significantly affects ASD risk. Autism Res 2017, 10: 1722–1736. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. Lay Summary Our results showed no evidence of significant association of either COMT rs4680 or 5-HTT 5-HTTLPR variants with ASD, showing that these two genes may not be major susceptible genetic factors in ASD occurrence, and may have a reciprocal action with each other in combination with environmental factors. These findings further provide evidence that a single gene variant may not dictate autism occurrence, but possibly contributes to a specific phenotype or subtype of ASD. En ligne : http://dx.doi.org/10.1002/aur.1822 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322
in Autism Research > 10-11 (November 2017) . - p.1722-1736[article] Associations of endocrine stress-related gene polymorphisms with risk of autism spectrum disorders: Evidence from an integrated meta-analysis [Texte imprimé et/ou numérique] / Ping-yuan YANG, Auteur ; Ya-jing MENGA, Auteur ; Tao LI, Auteur ; Yi HUANG, Auteur . - p.1722-1736.
Langues : Anglais (eng)
in Autism Research > 10-11 (November 2017) . - p.1722-1736
Mots-clés : autism spectrum disorders (ASD) catechol-O-methyl transferase (COMT) serotonin transporter stress response Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) are related to serotonin transporter (5-HTT) and catechol-O-methyl transferase (COMT) as two most monoaminergic polymorphic variations. However, multiple studies assessing rs4680 and 5-HTTLPR variants in ASD have reported inconsistent results. Therefore, we conducted an integrated meta-analysis to combine case-control and transmission/disequilibrium test (TDT) studies to determine whether COMT and 5-HTT are associated with ASD. We searched multiple electronic databases (PubMed, EmBase and Web of Science) to identify studies assessing the rs4680 and 5-HTTLPR variants in ASD from Jan 1997 to Dec 2016. Then allelic data from case–control and TDT studies were analyzed by the Catmap package in the R software. A total of 5 studies were eligible for the meta-analysis of rs4680, including 3 case–control, 1 TDT and 1 TDT & case–control studies. Meanwhile, 22 studies of 5-HTTLPR were available, including 16 TDT, 4 case–control and 2 TDT & case–control studies. The current meta-analysis included 814 ASD cases, 741 controls and 311 families related to rs4680; 749 ASD cases, 1,118 controls and 1,861 families relevant to 5-HTTLPR were also evaluated. For rs4680, the pooled OR was 1.18 (95% CI?=?0.87–1.59, P?=?0.29, Pheterogeneity?0.00001). There was no significant association of rs4680 with risk of ASD between the two subgroups. For 5-HTTLPR, the pooled OR was 1.05 (95% CI?=?0.92–1.20, P?=?0.4652, Pheterogeneity?0.00001). Meanwhile, we found no significant risk in individual case–control or TDT studies. The above findings indicated that neither COMT rs4680 nor 5-HTT 5-HTTLPR polymorphism significantly affects ASD risk. Autism Res 2017, 10: 1722–1736. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. Lay Summary Our results showed no evidence of significant association of either COMT rs4680 or 5-HTT 5-HTTLPR variants with ASD, showing that these two genes may not be major susceptible genetic factors in ASD occurrence, and may have a reciprocal action with each other in combination with environmental factors. These findings further provide evidence that a single gene variant may not dictate autism occurrence, but possibly contributes to a specific phenotype or subtype of ASD. En ligne : http://dx.doi.org/10.1002/aur.1822 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322 Atypical recognition of dynamic changes in facial expressions in autism spectrum disorders / Wataru SATO in Research in Autism Spectrum Disorders, 7-7 (July 2013)
[article]
Titre : Atypical recognition of dynamic changes in facial expressions in autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Wataru SATO, Auteur ; Shota UONO, Auteur ; Motomi TOICHI, Auteur Article en page(s) : p.906-912 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders (ASD) Dynamic facial expressions Naturalness Speed Index. décimale : PER Périodiques Résumé : Previous studies have suggested that the processing of dynamic facial expressions is impaired in autism spectrum disorders (ASD). However, the specific component that is impaired in the processing of dynamic facial expressions has not been identified. We investigated the recognition of dynamic changes in facial expressions among individuals with ASD and age- and sex-matched typically developing controls. Morphing animations of facial expressions of six emotions were presented at four different changing speeds, and participants rated the naturalness of the expression changes. The correspondence between reduced speeds and decreased naturalness ratings was weaker in the ASD than in the control group. These results suggest that the atypical visual analysis of dynamic changes in facial expressions underlies the impairment in real-life social interaction among individuals with ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2013.04.008 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=199
in Research in Autism Spectrum Disorders > 7-7 (July 2013) . - p.906-912[article] Atypical recognition of dynamic changes in facial expressions in autism spectrum disorders [Texte imprimé et/ou numérique] / Wataru SATO, Auteur ; Shota UONO, Auteur ; Motomi TOICHI, Auteur . - p.906-912.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 7-7 (July 2013) . - p.906-912
Mots-clés : Autism spectrum disorders (ASD) Dynamic facial expressions Naturalness Speed Index. décimale : PER Périodiques Résumé : Previous studies have suggested that the processing of dynamic facial expressions is impaired in autism spectrum disorders (ASD). However, the specific component that is impaired in the processing of dynamic facial expressions has not been identified. We investigated the recognition of dynamic changes in facial expressions among individuals with ASD and age- and sex-matched typically developing controls. Morphing animations of facial expressions of six emotions were presented at four different changing speeds, and participants rated the naturalness of the expression changes. The correspondence between reduced speeds and decreased naturalness ratings was weaker in the ASD than in the control group. These results suggest that the atypical visual analysis of dynamic changes in facial expressions underlies the impairment in real-life social interaction among individuals with ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2013.04.008 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=199 Behavioral and cardiac responses to emotional stroop in adults with autism spectrum disorders: influence of medication / Karen J. MATHEWSON in Autism Research, 4-2 (April 2011)
[article]
Titre : Behavioral and cardiac responses to emotional stroop in adults with autism spectrum disorders: influence of medication Type de document : Texte imprimé et/ou numérique Auteurs : Karen J. MATHEWSON, Auteur ; Irene E. DRMIC, Auteur ; Michelle K. JETHA, Auteur ; Susan E. BRYSON, Auteur ; Joel O. GOLDBERG, Auteur ; Geoffrey B. C. HALL, Auteur ; Diane L. SANTESSO, Auteur ; Sidney SEGALOWITZ, Auteur ; Louis A. SCHMIDT, Auteur Année de publication : 2011 Article en page(s) : p.98-108 Langues : Anglais (eng) Mots-clés : autism spectrum disorders (ASD) heart period respiratory sinus arrhythmia (RSA) Stroop task Index. décimale : PER Périodiques Résumé : Researchers have recently hypothesized that autism spectrum disorders (ASD) may be partly characterized by physiological over-arousal. One way to assess physiological arousal is through autonomic measures. Here heart period (HP) and parasympathetic activity measured by respiratory sinus arrhythmia (RSA) were examined in adults with ASD and matched controls at rest and during performance of an emotional Stroop task. Resting HP and RSA were lower in adults with ASD than in matched controls, consistent with hypothesized over-arousal in ASD. However, dividing the ASD group on the basis of antipsychotic medication usage revealed that group differences in autonomic arousal may be related to the effects of these medications or their correlates. Autonomic adjustments for Stroop performance were comparable across groups, but in the control group, larger RSA reductions were correlated with faster responding (i.e., better performance). This relation was reversed in the unmedicated ASD group and absent in the medicated ASD group. Findings highlight the importance of considering medication status in the recently burgeoning area of psychophysiological studies of autism. En ligne : http://dx.doi.org/10.1002/aur.176 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121
in Autism Research > 4-2 (April 2011) . - p.98-108[article] Behavioral and cardiac responses to emotional stroop in adults with autism spectrum disorders: influence of medication [Texte imprimé et/ou numérique] / Karen J. MATHEWSON, Auteur ; Irene E. DRMIC, Auteur ; Michelle K. JETHA, Auteur ; Susan E. BRYSON, Auteur ; Joel O. GOLDBERG, Auteur ; Geoffrey B. C. HALL, Auteur ; Diane L. SANTESSO, Auteur ; Sidney SEGALOWITZ, Auteur ; Louis A. SCHMIDT, Auteur . - 2011 . - p.98-108.
Langues : Anglais (eng)
in Autism Research > 4-2 (April 2011) . - p.98-108
Mots-clés : autism spectrum disorders (ASD) heart period respiratory sinus arrhythmia (RSA) Stroop task Index. décimale : PER Périodiques Résumé : Researchers have recently hypothesized that autism spectrum disorders (ASD) may be partly characterized by physiological over-arousal. One way to assess physiological arousal is through autonomic measures. Here heart period (HP) and parasympathetic activity measured by respiratory sinus arrhythmia (RSA) were examined in adults with ASD and matched controls at rest and during performance of an emotional Stroop task. Resting HP and RSA were lower in adults with ASD than in matched controls, consistent with hypothesized over-arousal in ASD. However, dividing the ASD group on the basis of antipsychotic medication usage revealed that group differences in autonomic arousal may be related to the effects of these medications or their correlates. Autonomic adjustments for Stroop performance were comparable across groups, but in the control group, larger RSA reductions were correlated with faster responding (i.e., better performance). This relation was reversed in the unmedicated ASD group and absent in the medicated ASD group. Findings highlight the importance of considering medication status in the recently burgeoning area of psychophysiological studies of autism. En ligne : http://dx.doi.org/10.1002/aur.176 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121 Brief Report: Diminishing Geographic Variability in Autism Spectrum Disorders Over Time? / Kate HOFFMAN in Journal of Autism and Developmental Disorders, 44-3 (March 2014)
PermalinkElephants in Pyjamas: Testing the Weak Central Coherence Account of Autism Spectrum Disorders Using a Syntactic Disambiguation Task / N. G. RICHES in Journal of Autism and Developmental Disorders, 46-1 (January 2016)
PermalinkHealth Disparities among Children with Autism Spectrum Disorders: Analysis of the National Survey of Children's Health 2016 / A. KARPUR in Journal of Autism and Developmental Disorders, 49-4 (April 2019)
PermalinkImpaired Overt Facial Mimicry in Response to Dynamic Facial Expressions in High-Functioning Autism Spectrum Disorders / Sayaka YOSHIMURA in Journal of Autism and Developmental Disorders, 45-5 (May 2015)
PermalinkNeural mechanisms of negative reinforcement in children and adolescents with autism spectrum disorders / Cara R. DAMIANO in Journal of Neurodevelopmental Disorders, 7-1 (December 2015)
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