A Bayesian multilevel analysis of the longitudinal associations between relationship quality and suicidal ideation and attempts among youth with bipolar disorder / C. J. R. SEWALL in Journal of Child Psychology and Psychiatry, 62-7 (July 2021)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 62-7 (July 2021) . - p.905-915 Titre : A Bayesian multilevel analysis of the longitudinal associations between relationship quality and suicidal ideation and attempts among youth with bipolar disorder Type de document : Texte imprimé et/ou numérique Auteurs : C. J. R. SEWALL, Auteur ; J. M. GIRARD, Auteur ; J. MERRANKO, Auteur ; D. HAFEMAN, Auteur ; B. I. GOLDSTEIN, Auteur ; M. STROBER, Auteur ; H. HOWER, Auteur ; L. M. WEINSTOCK, Auteur ; S. YEN, Auteur ; N. D. RYAN, Auteur ; M. B. KELLER, Auteur ; F. LIAO, Auteur ; Rasim S. DILER, Auteur ; M. KAY GILL, Auteur ; David A. AXELSON, Auteur ; Boris BIRMAHER, Auteur ; Tina R. GOLDSTEIN, Auteur Article en page(s) : p.905-915 Langues : Anglais (eng) Mots-clés : Adolescent  Bayes Theorem  Bipolar Disorder/epidemiology  Humans  Multilevel Analysis  Risk Factors  Suicidal Ideation  Suicide, Attempted  Bayesian analysis  Suicide  adolescence  bipolar disorder  parent-child relationships  peer relationships Index. décimale : PER Périodiques Résumé : BACKGROUND: Youth with bipolar disorder (BD) are at high risk for suicidal thoughts and behaviors and frequently experience interpersonal impairment, which is a risk factor for suicide. Yet, no study to date has examined the longitudinal associations between relationship quality in family/peer domains and suicidal thoughts and behaviors among youth with BD. Thus, we investigated how between-person differences - reflecting the average relationship quality across time - and within-person changes, reflecting recent fluctuations in relationship quality, act as distal and/or proximal risk factors for suicidal ideation (SI) and suicide attempts. METHODS: We used longitudinal data from the Course and Outcome of Bipolar Youth Study (N = 413). Relationship quality variables were decomposed into stable (i.e., average) and varying (i.e., recent) components and entered, along with major clinical covariates, into separate Bayesian multilevel models predicting SI and suicide attempt. We also examined how the relationship quality effects interacted with age and sex. RESULTS: Poorer average relationship quality with parents (? = -.33, 95% Bayesian highest density interval (HDI) [-0.54, -0.11]) or friends (? = -.33, 95% HDI [-0.55, -0.11]) was longitudinally associated with increased risk of SI but not suicide attempt. Worsening recent relationship quality with parents (? = -.10, 95% HDI [-0.19, -0.03]) and, to a lesser extent, friends (? = -.06, 95% HDI [-0.15, 0.03]) was longitudinally associated with increased risk of SI, but only worsening recent relationship quality with parents was also associated with increased risk of suicide attempt (? = -.15, 95% HDI [-0.31, 0.01]). The effects of certain relationship quality variables were moderated by gender but not age. CONCLUSIONS: Among youth with BD, having poorer average relationship quality with peers and/or parents represents a distal risk factor for SI but not suicide attempts. Additionally, worsening recent relationship quality with parents may be a time-sensitive indicator of increased risk for SI or suicide attempt. En ligne : http://dx.doi.org/10.1111/jcpp.13343 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 [article] A Bayesian multilevel analysis of the longitudinal associations between relationship quality and suicidal ideation and attempts among youth with bipolar disorder [Texte imprimé et/ou numérique] / C. J. R. SEWALL, Auteur ; J. M. GIRARD, Auteur ; J. MERRANKO, Auteur ; D. HAFEMAN, Auteur ; B. I. GOLDSTEIN, Auteur ; M. STROBER, Auteur ; H. HOWER, Auteur ; L. M. WEINSTOCK, Auteur ; S. YEN, Auteur ; N. D. RYAN, Auteur ; M. B. KELLER, Auteur ; F. LIAO, Auteur ; Rasim S. DILER, Auteur ; M. KAY GILL, Auteur ; David A. AXELSON, Auteur ; Boris BIRMAHER, Auteur ; Tina R. GOLDSTEIN, Auteur . - p.905-915. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 62-7 (July 2021) . - p.905-915 Mots-clés : Adolescent  Bayes Theorem  Bipolar Disorder/epidemiology  Humans  Multilevel Analysis  Risk Factors  Suicidal Ideation  Suicide, Attempted  Bayesian analysis  Suicide  adolescence  bipolar disorder  parent-child relationships  peer relationships Index. décimale : PER Périodiques Résumé : BACKGROUND: Youth with bipolar disorder (BD) are at high risk for suicidal thoughts and behaviors and frequently experience interpersonal impairment, which is a risk factor for suicide. Yet, no study to date has examined the longitudinal associations between relationship quality in family/peer domains and suicidal thoughts and behaviors among youth with BD. Thus, we investigated how between-person differences - reflecting the average relationship quality across time - and within-person changes, reflecting recent fluctuations in relationship quality, act as distal and/or proximal risk factors for suicidal ideation (SI) and suicide attempts. METHODS: We used longitudinal data from the Course and Outcome of Bipolar Youth Study (N = 413). Relationship quality variables were decomposed into stable (i.e., average) and varying (i.e., recent) components and entered, along with major clinical covariates, into separate Bayesian multilevel models predicting SI and suicide attempt. We also examined how the relationship quality effects interacted with age and sex. RESULTS: Poorer average relationship quality with parents (? = -.33, 95% Bayesian highest density interval (HDI) [-0.54, -0.11]) or friends (? = -.33, 95% HDI [-0.55, -0.11]) was longitudinally associated with increased risk of SI but not suicide attempt. Worsening recent relationship quality with parents (? = -.10, 95% HDI [-0.19, -0.03]) and, to a lesser extent, friends (? = -.06, 95% HDI [-0.15, 0.03]) was longitudinally associated with increased risk of SI, but only worsening recent relationship quality with parents was also associated with increased risk of suicide attempt (? = -.15, 95% HDI [-0.31, 0.01]). The effects of certain relationship quality variables were moderated by gender but not age. CONCLUSIONS: Among youth with BD, having poorer average relationship quality with peers and/or parents represents a distal risk factor for SI but not suicide attempts. Additionally, worsening recent relationship quality with parents may be a time-sensitive indicator of increased risk for SI or suicide attempt. En ligne : http://dx.doi.org/10.1111/jcpp.13343 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456

Error-related brain activity in pediatric anxiety disorders remains elevated following individual therapy: a randomized clinical trial / Cecile D. LADOUCEUR in Journal of Child Psychology and Psychiatry, 59-11 (November 2018)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 59-11 (November 2018) . - p.1152-1161 Titre : Error-related brain activity in pediatric anxiety disorders remains elevated following individual therapy: a randomized clinical trial Type de document : Texte imprimé et/ou numérique Auteurs : Cecile D. LADOUCEUR, Auteur ; P. Z. TAN, Auteur ; V. SHARMA, Auteur ; L. M. BYLSMA, Auteur ; J. S. SILK, Auteur ; G. J. SIEGLE, Auteur ; E. E. FORBES, Auteur ; D. L. MCMAKIN, Auteur ; Ronald E. DAHL, Auteur ; P. C. KENDALL, Auteur ; A. MANNARINO, Auteur ; N. D. RYAN, Auteur Article en page(s) : p.1152-1161 Langues : Anglais (eng) Mots-clés : Error-related negativity  child-centered therapy  cognitive-behavioral therapy  electroencephalography  pediatric anxiety disorders Index. décimale : PER Périodiques Résumé : BACKGROUND: Anxiety disorders are associated with an overactive action monitoring system as indexed by a larger error-related negativity (ERN). This study tests whether ERN magnitude changes following treatment, predicts response to treatment, and varies by treatment type. METHODS: The sample included 130 youth (9-14 years): youth with an anxiety disorder (ANX; n = 100) and healthy control (HC; n = 30) youth with no lifetime DSM-IV disorders. ANX youth were randomized to either a manualized cognitive-behavior therapy (CBT) or a comparison child-centered therapy (CCT). The ERN was assessed before and after 16 sessions of treatment and within a comparable interval for HC. Subjective ratings about making errors on the task were obtained following each testing session. The ClinicalTrials.gov identifier is NCT00774150. RESULTS: The ERN was larger in ANX than HC youth but ERN magnitude did not significantly change following treatment in the ANX youth, regardless of treatment type, and baseline ERN did not predict treatment response. Post-task ratings revealed that ANX youth worried more about task performance feedback than HC. Like the ERN, mean ratings did not significantly change following treatment. However, these ratings were not correlated with ERN amplitude. CONCLUSIONS: Findings of greater ERN in pediatric anxiety disorders are replicated in a larger sample. More importantly, findings from this randomized control trial show that a larger ERN and feeling worried about performance feedback remain unchanged following treatment and are unrelated to treatment response. Such findings suggest that action monitoring systems remain overactive in anxious youth treated with psychotherapy, suggesting the need for future investigation of whether novel complimentary cognitive and emotional training programs can modify these systems would be warranted. En ligne : http://dx.doi.org/10.1111/jcpp.12900 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370 [article] Error-related brain activity in pediatric anxiety disorders remains elevated following individual therapy: a randomized clinical trial [Texte imprimé et/ou numérique] / Cecile D. LADOUCEUR, Auteur ; P. Z. TAN, Auteur ; V. SHARMA, Auteur ; L. M. BYLSMA, Auteur ; J. S. SILK, Auteur ; G. J. SIEGLE, Auteur ; E. E. FORBES, Auteur ; D. L. MCMAKIN, Auteur ; Ronald E. DAHL, Auteur ; P. C. KENDALL, Auteur ; A. MANNARINO, Auteur ; N. D. RYAN, Auteur . - p.1152-1161. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 59-11 (November 2018) . - p.1152-1161 Mots-clés : Error-related negativity  child-centered therapy  cognitive-behavioral therapy  electroencephalography  pediatric anxiety disorders Index. décimale : PER Périodiques Résumé : BACKGROUND: Anxiety disorders are associated with an overactive action monitoring system as indexed by a larger error-related negativity (ERN). This study tests whether ERN magnitude changes following treatment, predicts response to treatment, and varies by treatment type. METHODS: The sample included 130 youth (9-14 years): youth with an anxiety disorder (ANX; n = 100) and healthy control (HC; n = 30) youth with no lifetime DSM-IV disorders. ANX youth were randomized to either a manualized cognitive-behavior therapy (CBT) or a comparison child-centered therapy (CCT). The ERN was assessed before and after 16 sessions of treatment and within a comparable interval for HC. Subjective ratings about making errors on the task were obtained following each testing session. The ClinicalTrials.gov identifier is NCT00774150. RESULTS: The ERN was larger in ANX than HC youth but ERN magnitude did not significantly change following treatment in the ANX youth, regardless of treatment type, and baseline ERN did not predict treatment response. Post-task ratings revealed that ANX youth worried more about task performance feedback than HC. Like the ERN, mean ratings did not significantly change following treatment. However, these ratings were not correlated with ERN amplitude. CONCLUSIONS: Findings of greater ERN in pediatric anxiety disorders are replicated in a larger sample. More importantly, findings from this randomized control trial show that a larger ERN and feeling worried about performance feedback remain unchanged following treatment and are unrelated to treatment response. Such findings suggest that action monitoring systems remain overactive in anxious youth treated with psychotherapy, suggesting the need for future investigation of whether novel complimentary cognitive and emotional training programs can modify these systems would be warranted. En ligne : http://dx.doi.org/10.1111/jcpp.12900 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370

Vigilant attention to threat, sleep patterns, and anxiety in peripubertal youth / E. J. RICKETTS in Journal of Child Psychology and Psychiatry, 59-12 (December 2018)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 59-12 (December 2018) . - p.1309-1322 Titre : Vigilant attention to threat, sleep patterns, and anxiety in peripubertal youth Type de document : Texte imprimé et/ou numérique Auteurs : E. J. RICKETTS, Auteur ; R. B. PRICE, Auteur ; G. J. SIEGLE, Auteur ; J. S. SILK, Auteur ; E. E. FORBES, Auteur ; Cecile D. LADOUCEUR, Auteur ; A. G. HARVEY, Auteur ; N. D. RYAN, Auteur ; Ronald E. DAHL, Auteur ; D. L. MCMAKIN, Auteur Article en page(s) : p.1309-1322 Langues : Anglais (eng) Mots-clés : Sleep  adolescence  anxiety Index. décimale : PER Périodiques Résumé : BACKGROUND: Vigilant attention to threat is commonly observed in anxiety, undergoes developmental changes in early adolescence, and has been proposed to interfere with sleep initiation and maintenance. We present one of the first studies to use objective measures to examine associations between vigilant attention to threat and difficulties initiating and maintaining sleep in an early adolescent anxious sample. We also explore the moderating role of development (age, puberty) and sex. METHODS: Participants were 66 peripubertal youth (ages 9-14) with a primary anxiety disorder and 24 healthy control subjects. A dot-probe task was used to assess attentional bias to fearful relative to neutral face stimuli. Eye-tracking indexed selective attentional bias to threat, and reaction time bias indexed action readiness to threat. Sleep was assessed via actigraphy (e.g. sleep onset delay, wake after sleep onset, etc.), parent report (Children's Sleep Habits Questionnaire), and child report (Sleep Self-Report). The Pediatric Anxiety Rating Scale assessed anxiety severity. RESULTS: Eye-tracking initial threat fixation bias (beta = .33, p = .001) and threat dwell time bias (beta = .22, p = .041) were positively associated with sleep onset latency. Reaction time bias was positively associated with wake after sleep onset (beta = .24, p = .026) and parent-reported sleep disturbance (beta = .25, p = .019). Anxiety (severity, diagnosis) was not associated with these outcomes. Sex (beta = -.32, p = .036) moderated the relation between initial threat fixation bias and sleep onset latency, with a positive association for males (p = .005), but not for females (p = .289). Age and pubertal status did not moderate effects. CONCLUSIONS: Vigilant attention to threat is related to longer sleep onset and reduced sleep maintenance. These associations are not stronger in early adolescents with anxiety. Implications for early intervention or prevention that targets vigilant attention to threat to impact sleep disturbance, and vice versa, are discussed. En ligne : http://dx.doi.org/10.1111/jcpp.12923 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=371 [article] Vigilant attention to threat, sleep patterns, and anxiety in peripubertal youth [Texte imprimé et/ou numérique] / E. J. RICKETTS, Auteur ; R. B. PRICE, Auteur ; G. J. SIEGLE, Auteur ; J. S. SILK, Auteur ; E. E. FORBES, Auteur ; Cecile D. LADOUCEUR, Auteur ; A. G. HARVEY, Auteur ; N. D. RYAN, Auteur ; Ronald E. DAHL, Auteur ; D. L. MCMAKIN, Auteur . - p.1309-1322. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 59-12 (December 2018) . - p.1309-1322 Mots-clés : Sleep  adolescence  anxiety Index. décimale : PER Périodiques Résumé : BACKGROUND: Vigilant attention to threat is commonly observed in anxiety, undergoes developmental changes in early adolescence, and has been proposed to interfere with sleep initiation and maintenance. We present one of the first studies to use objective measures to examine associations between vigilant attention to threat and difficulties initiating and maintaining sleep in an early adolescent anxious sample. We also explore the moderating role of development (age, puberty) and sex. METHODS: Participants were 66 peripubertal youth (ages 9-14) with a primary anxiety disorder and 24 healthy control subjects. A dot-probe task was used to assess attentional bias to fearful relative to neutral face stimuli. Eye-tracking indexed selective attentional bias to threat, and reaction time bias indexed action readiness to threat. Sleep was assessed via actigraphy (e.g. sleep onset delay, wake after sleep onset, etc.), parent report (Children's Sleep Habits Questionnaire), and child report (Sleep Self-Report). The Pediatric Anxiety Rating Scale assessed anxiety severity. RESULTS: Eye-tracking initial threat fixation bias (beta = .33, p = .001) and threat dwell time bias (beta = .22, p = .041) were positively associated with sleep onset latency. Reaction time bias was positively associated with wake after sleep onset (beta = .24, p = .026) and parent-reported sleep disturbance (beta = .25, p = .019). Anxiety (severity, diagnosis) was not associated with these outcomes. Sex (beta = -.32, p = .036) moderated the relation between initial threat fixation bias and sleep onset latency, with a positive association for males (p = .005), but not for females (p = .289). Age and pubertal status did not moderate effects. CONCLUSIONS: Vigilant attention to threat is related to longer sleep onset and reduced sleep maintenance. These associations are not stronger in early adolescents with anxiety. Implications for early intervention or prevention that targets vigilant attention to threat to impact sleep disturbance, and vice versa, are discussed. En ligne : http://dx.doi.org/10.1111/jcpp.12923 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=371

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