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Auteur G. PERLMAN |
Documents disponibles écrits par cet auteur (2)



Differential outcomes of tonic and phasic irritability in adolescent girls / J. SILVER in Journal of Child Psychology and Psychiatry, 62-10 (October 2021)
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Titre : Differential outcomes of tonic and phasic irritability in adolescent girls Type de document : Texte imprimé et/ou numérique Auteurs : J. SILVER, Auteur ; Gabrielle A. CARLSON, Auteur ; T. M. OLINO, Auteur ; G. PERLMAN, Auteur ; D. MACKIN, Auteur ; R. KOTOV, Auteur ; D. N. KLEIN, Auteur Article en page(s) : p.1220-1227 Langues : Anglais (eng) Mots-clés : Adolescent Anxiety Disorders Attention Deficit and Disruptive Behavior Disorders Female Humans Irritable Mood Longitudinal Studies Personality Temperament irritability longitudinal outcomes Index. décimale : PER Périodiques Résumé : BACKGROUND: Irritable mood is a transdiagnostic clinical feature that is present in multiple psychiatric disorders. Although irritability is frequently examined as a unitary construct, two dimensions of irritability, tonic (i.e., irritable mood) and phasic (i.e., temper outbursts), have been hypothesized. However, few studies have examined whether tonic and phasic irritability are empirically separable and predict different forms of psychopathology. METHODS: We utilized data from a longitudinal study of a community sample of 550 girls (age 13.5-15.5 years) followed at 9-month intervals for 3 years. We conducted exploratory factor analysis (EFA) using items from three self-report inventories: the International Personality Item Pool Anger scale, Temperament and Affectivity Inventory Anger scale, and Buss-Perry Aggression Questionnaire Anger scale. RESULTS: The EFA identified dimensions that were consistent with tonic and phasic irritability. Tonic irritability at baseline independently predicted the development of depressive disorders and generalized anxiety disorder (GAD) in subsequent waves. Phasic irritability independently predicted a decreased probability of GAD, but an increased probability of oppositional defiant, conduct, and substance use disorder, and greater risky sexual behavior and relational aggression during the follow-up. CONCLUSIONS: Tonic and phasic irritability appear to be separable constructs with unique implications for later psychopathology and related behavior among adolescent girls. It is important to consider this distinction in research on the etiology and pathophysiology of irritability and developing effective treatments. En ligne : http://dx.doi.org/10.1111/jcpp.13402 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456
in Journal of Child Psychology and Psychiatry > 62-10 (October 2021) . - p.1220-1227[article] Differential outcomes of tonic and phasic irritability in adolescent girls [Texte imprimé et/ou numérique] / J. SILVER, Auteur ; Gabrielle A. CARLSON, Auteur ; T. M. OLINO, Auteur ; G. PERLMAN, Auteur ; D. MACKIN, Auteur ; R. KOTOV, Auteur ; D. N. KLEIN, Auteur . - p.1220-1227.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 62-10 (October 2021) . - p.1220-1227
Mots-clés : Adolescent Anxiety Disorders Attention Deficit and Disruptive Behavior Disorders Female Humans Irritable Mood Longitudinal Studies Personality Temperament irritability longitudinal outcomes Index. décimale : PER Périodiques Résumé : BACKGROUND: Irritable mood is a transdiagnostic clinical feature that is present in multiple psychiatric disorders. Although irritability is frequently examined as a unitary construct, two dimensions of irritability, tonic (i.e., irritable mood) and phasic (i.e., temper outbursts), have been hypothesized. However, few studies have examined whether tonic and phasic irritability are empirically separable and predict different forms of psychopathology. METHODS: We utilized data from a longitudinal study of a community sample of 550 girls (age 13.5-15.5 years) followed at 9-month intervals for 3 years. We conducted exploratory factor analysis (EFA) using items from three self-report inventories: the International Personality Item Pool Anger scale, Temperament and Affectivity Inventory Anger scale, and Buss-Perry Aggression Questionnaire Anger scale. RESULTS: The EFA identified dimensions that were consistent with tonic and phasic irritability. Tonic irritability at baseline independently predicted the development of depressive disorders and generalized anxiety disorder (GAD) in subsequent waves. Phasic irritability independently predicted a decreased probability of GAD, but an increased probability of oppositional defiant, conduct, and substance use disorder, and greater risky sexual behavior and relational aggression during the follow-up. CONCLUSIONS: Tonic and phasic irritability appear to be separable constructs with unique implications for later psychopathology and related behavior among adolescent girls. It is important to consider this distinction in research on the etiology and pathophysiology of irritability and developing effective treatments. En ligne : http://dx.doi.org/10.1111/jcpp.13402 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 A neural biomarker, the error-related negativity, predicts the first onset of generalized anxiety disorder in a large sample of adolescent females / A. MEYER in Journal of Child Psychology and Psychiatry, 59-11 (November 2018)
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Titre : A neural biomarker, the error-related negativity, predicts the first onset of generalized anxiety disorder in a large sample of adolescent females Type de document : Texte imprimé et/ou numérique Auteurs : A. MEYER, Auteur ; B. NELSON, Auteur ; G. PERLMAN, Auteur ; D. N. KLEIN, Auteur ; R. KOTOV, Auteur Article en page(s) : p.1162-1170 Langues : Anglais (eng) Mots-clés : Adolescence anxiety biomarkers event-related potential Index. décimale : PER Périodiques Résumé : OBJECTIVE: An increased neural response to making mistakes has emerged as a potential biomarker of anxiety across development. The error-related negativity (ERN) is an event-related potential elicited when people make mistakes on simple laboratory-based reaction time tasks that has been associated with risk for anxiety. This study examined whether the ERN prospectively predicted the first onset of generalized anxiety disorder (GAD) over 1.5 years in adolescent girls. METHODS: The sample included 457 girls between the ages of 13.5 and 15.5 years, with no history of GAD. At baseline, the ERN was measured using a flankers task. Psychiatric history of the adolescent and biological parent was assessed with diagnostic interviews, and the adolescent completed a self-report questionnaire regarding anxiety symptoms. Approximately 1.5 years later, adolescents completed the same interview. RESULTS: An increased neural response to errors at baseline predicted first-onset GAD over 1.5 years. The ERN was a significant predictor independent of other prominent risk factors, including baseline anxiety and depression symptoms and parental lifetime psychiatric history. Jointly the ERN and social anxiety symptoms provided the greatest power for predicting first-onset GAD. CONCLUSIONS: This study provides evidence for the utility of the ERN as a biomarker of risk for GAD during a key developmental period. En ligne : http://dx.doi.org/10.1111/jcpp.12922 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370
in Journal of Child Psychology and Psychiatry > 59-11 (November 2018) . - p.1162-1170[article] A neural biomarker, the error-related negativity, predicts the first onset of generalized anxiety disorder in a large sample of adolescent females [Texte imprimé et/ou numérique] / A. MEYER, Auteur ; B. NELSON, Auteur ; G. PERLMAN, Auteur ; D. N. KLEIN, Auteur ; R. KOTOV, Auteur . - p.1162-1170.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 59-11 (November 2018) . - p.1162-1170
Mots-clés : Adolescence anxiety biomarkers event-related potential Index. décimale : PER Périodiques Résumé : OBJECTIVE: An increased neural response to making mistakes has emerged as a potential biomarker of anxiety across development. The error-related negativity (ERN) is an event-related potential elicited when people make mistakes on simple laboratory-based reaction time tasks that has been associated with risk for anxiety. This study examined whether the ERN prospectively predicted the first onset of generalized anxiety disorder (GAD) over 1.5 years in adolescent girls. METHODS: The sample included 457 girls between the ages of 13.5 and 15.5 years, with no history of GAD. At baseline, the ERN was measured using a flankers task. Psychiatric history of the adolescent and biological parent was assessed with diagnostic interviews, and the adolescent completed a self-report questionnaire regarding anxiety symptoms. Approximately 1.5 years later, adolescents completed the same interview. RESULTS: An increased neural response to errors at baseline predicted first-onset GAD over 1.5 years. The ERN was a significant predictor independent of other prominent risk factors, including baseline anxiety and depression symptoms and parental lifetime psychiatric history. Jointly the ERN and social anxiety symptoms provided the greatest power for predicting first-onset GAD. CONCLUSIONS: This study provides evidence for the utility of the ERN as a biomarker of risk for GAD during a key developmental period. En ligne : http://dx.doi.org/10.1111/jcpp.12922 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370