Anxiety Disorders in Adults with Autism Spectrum Disorder: A Population-Based Study / Victoria NIMMO-SMITH in Journal of Autism and Developmental Disorders, 50-1 (January 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-1 (January 2020) . - p.308-318 Titre : Anxiety Disorders in Adults with Autism Spectrum Disorder: A Population-Based Study Type de document : Texte imprimé et/ou numérique Auteurs : Victoria NIMMO-SMITH, Auteur ; Hein HEUVELMAN, Auteur ; Christina DALMAN, Auteur ; Michael LUNDBERG, Auteur ; Selma IDRING, Auteur ; Peter CARPENTER, Auteur ; Cecilia MAGNUSSON, Auteur ; Dheeraj RAI, Auteur Article en page(s) : p.308-318 Langues : Anglais (eng) Mots-clés : Anxiety  Autism spectrum disorder  Epidemiology  Intellectual disability  Mental health Index. décimale : PER Périodiques Résumé : Anxiety is common in children with ASD; however, the burden of specific anxiety disorders for adults with ASD is under-researched. Using the Stockholm Youth Cohort, we compared anxiety disorder diagnoses among autistic adults (n = 4049), with or without intellectual disability, and population controls (n = 217,645). We conducted additional sibling analyses. Anxiety disorders were diagnosed in 20.1% of adults with ASD compared with 8.7% of controls (RR = 2.62 [95% CI 2.47-2.79]), with greatest risk for autistic people without intellectual disability. Rates of almost all individual anxiety disorders were raised, notably obsessive-compulsive disorder and phobic anxiety disorders. Anxiety disorders were more common in full siblings and half-siblings of people with ASD. The implications of this are explored. En ligne : http://dx.doi.org/10.1007/s10803-019-04234-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=414 [article] Anxiety Disorders in Adults with Autism Spectrum Disorder: A Population-Based Study [Texte imprimé et/ou numérique] / Victoria NIMMO-SMITH, Auteur ; Hein HEUVELMAN, Auteur ; Christina DALMAN, Auteur ; Michael LUNDBERG, Auteur ; Selma IDRING, Auteur ; Peter CARPENTER, Auteur ; Cecilia MAGNUSSON, Auteur ; Dheeraj RAI, Auteur . - p.308-318. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-1 (January 2020) . - p.308-318 Mots-clés : Anxiety  Autism spectrum disorder  Epidemiology  Intellectual disability  Mental health Index. décimale : PER Périodiques Résumé : Anxiety is common in children with ASD; however, the burden of specific anxiety disorders for adults with ASD is under-researched. Using the Stockholm Youth Cohort, we compared anxiety disorder diagnoses among autistic adults (n = 4049), with or without intellectual disability, and population controls (n = 217,645). We conducted additional sibling analyses. Anxiety disorders were diagnosed in 20.1% of adults with ASD compared with 8.7% of controls (RR = 2.62 [95% CI 2.47-2.79]), with greatest risk for autistic people without intellectual disability. Rates of almost all individual anxiety disorders were raised, notably obsessive-compulsive disorder and phobic anxiety disorders. Anxiety disorders were more common in full siblings and half-siblings of people with ASD. The implications of this are explored. En ligne : http://dx.doi.org/10.1007/s10803-019-04234-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=414

Gendered play behaviours in autistic and non-autistic children: A population-based cohort study / Laura HULL in Autism, 27-5 (July 2023)  

Public ISBD [article]  inAutism > 27-5 (July 2023) . - p.1449-1460 Titre : Gendered play behaviours in autistic and non-autistic children: A population-based cohort study Type de document : Texte imprimé et/ou numérique Auteurs : Laura HULL, Auteur ; Hein HEUVELMAN, Auteur ; Jean GOLDING, Auteur ; William MANDY, Auteur ; Dheeraj RAI, Auteur Article en page(s) : p.1449-1460 Langues : Anglais (eng) Mots-clés : development;gender;play;sex Index. décimale : PER Périodiques Résumé : Gender-typical play is observed throughout childhood for non-autistic children. However, there has been limited research into the gender typicality of autistic children?s play compared to that of non-autistic children. In a longitudinal population-based cohort, we compared gendered play behaviours in autistic and non-autistic children using standardised parent-report (30, 42 and 57?months) and child-report (8?years) data (N?=?11,251). We observed no difference in gendered play behaviours between girls with or without autism at any time point. Autistic and non-autistic boys did not differ in the gender typicality of their play when aged 30?months, but the play of autistic boys appeared less masculine than that of non-autistic boys (??=??1.1, 95% confidence interval?=??2.1 to ?0.2; and ??=??2.6, 95% confidence interval?=??4.7 to ?0.5) at 42 and 57?months. Autistic boys also self-reported less masculine play behaviours than non-autistic boys at 8?years of age (??=??3.4, 95% confidence interval?=??6.6 to ?0.2). We found that autistic boys' play was less gender typical than that of non-autistic boys in middle and later childhood. Our findings highlight the importance of examining gendered play behaviours in a developmental context and have relevance for understanding the development of gender identity in autism. Lay abstract Non-autistic children tend to show gendered patterns of play behaviours - boys are more likely to play with "masculine" toys, and girls are more likely to play with "feminine" toys. However, little is known about whether autistic children follow these patterns as well. We looked at the masculinity and femininity of autistic and non-autistic children?s play behaviours at multiple time points. Parents reported their children?s play behaviours at ages 30, 42 and 57?months, and children reported their own play behaviours at 8?years old. We found no difference between autistic and non-autistic girls, who both showed more feminine play behaviours as they got older. Autistic boys' play behaviours were reported as less masculine than non-autistic boys at 42 and 57?months, and at 8?years old. We also found that non-autistic boys' play tended to become more masculine as they got older, but this was not the case for autistic boys. Our findings suggest that differences in autistic and non-autistic boys' play behaviours may develop at around 42?months old. En ligne : http://dx.doi.org/10.1177/13623613221139373 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=507 [article] Gendered play behaviours in autistic and non-autistic children: A population-based cohort study [Texte imprimé et/ou numérique] / Laura HULL, Auteur ; Hein HEUVELMAN, Auteur ; Jean GOLDING, Auteur ; William MANDY, Auteur ; Dheeraj RAI, Auteur . - p.1449-1460. Langues : Anglais (eng) in Autism > 27-5 (July 2023) . - p.1449-1460 Mots-clés : development;gender;play;sex Index. décimale : PER Périodiques Résumé : Gender-typical play is observed throughout childhood for non-autistic children. However, there has been limited research into the gender typicality of autistic children?s play compared to that of non-autistic children. In a longitudinal population-based cohort, we compared gendered play behaviours in autistic and non-autistic children using standardised parent-report (30, 42 and 57?months) and child-report (8?years) data (N?=?11,251). We observed no difference in gendered play behaviours between girls with or without autism at any time point. Autistic and non-autistic boys did not differ in the gender typicality of their play when aged 30?months, but the play of autistic boys appeared less masculine than that of non-autistic boys (??=??1.1, 95% confidence interval?=??2.1 to ?0.2; and ??=??2.6, 95% confidence interval?=??4.7 to ?0.5) at 42 and 57?months. Autistic boys also self-reported less masculine play behaviours than non-autistic boys at 8?years of age (??=??3.4, 95% confidence interval?=??6.6 to ?0.2). We found that autistic boys' play was less gender typical than that of non-autistic boys in middle and later childhood. Our findings highlight the importance of examining gendered play behaviours in a developmental context and have relevance for understanding the development of gender identity in autism. Lay abstract Non-autistic children tend to show gendered patterns of play behaviours - boys are more likely to play with "masculine" toys, and girls are more likely to play with "feminine" toys. However, little is known about whether autistic children follow these patterns as well. We looked at the masculinity and femininity of autistic and non-autistic children?s play behaviours at multiple time points. Parents reported their children?s play behaviours at ages 30, 42 and 57?months, and children reported their own play behaviours at 8?years old. We found no difference between autistic and non-autistic girls, who both showed more feminine play behaviours as they got older. Autistic boys' play behaviours were reported as less masculine than non-autistic boys at 42 and 57?months, and at 8?years old. We also found that non-autistic boys' play tended to become more masculine as they got older, but this was not the case for autistic boys. Our findings suggest that differences in autistic and non-autistic boys' play behaviours may develop at around 42?months old. En ligne : http://dx.doi.org/10.1177/13623613221139373 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=507

Sex bias in autism spectrum disorder in neurofibromatosis type 1 / S. GARG in Journal of Neurodevelopmental Disorders, 8-1 (December 2016)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 8-1 (December 2016) . - p.26 Titre : Sex bias in autism spectrum disorder in neurofibromatosis type 1 Type de document : Texte imprimé et/ou numérique Auteurs : S. GARG, Auteur ; Hein HEUVELMAN, Auteur ; S. HUSON, Auteur ; H. TOBIN, Auteur ; J. GREEN, Auteur Article en page(s) : p.26 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Neurofibromatosis type 1  Sex bias  Syndromic autism Index. décimale : PER Périodiques Résumé : BACKGROUND: Despite extensive literature, little is known about the mechanisms underlying sex bias in autism spectrum disorder (ASD). This study investigates the sex differences in ASD associated with neurofibromatosis type 1, a single-gene model of syndromic autism. METHODS: We analysed data from n = 194 children aged 4-16 years with neurofibromatosis type 1. Sex differences were evaluated across the Autism Diagnostic Interview-Revised (ADI-R), Autism Diagnostic Observation Schedule (ADOS), verbal IQ, Social Responsiveness Scale (SRS) and Conners questionnaires. RESULTS: There was 2.68:1 male:female ratio in children meeting ASD criteria on the deep phenotyping measures. On symptom profile, males with neurofibromatosis type 1 (NF1) + ASD were more impaired on reciprocal social interaction and communication domains of the ADI-R but we found no differences on the restricted, repetitive behaviours (RRBs) domain of the ADI-R and no differences on the social on the ADOS. NF1 ASD males and females were comparable on verbal IQ, and the inattention/hyperactivity domains of the Conners questionnaire. CONCLUSIONS: There is a significant male bias in the prevalence of ASD in NF1. The phenotypic profile of NF1 + ASD cases includes greater social communication impairment in males. We discuss the implications of our findings and the rationale for using NF1 as a model for investigating sex bias in idiopathic ASD. En ligne : http://dx.doi.org/10.1186/s11689-016-9159-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=349 [article] Sex bias in autism spectrum disorder in neurofibromatosis type 1 [Texte imprimé et/ou numérique] / S. GARG, Auteur ; Hein HEUVELMAN, Auteur ; S. HUSON, Auteur ; H. TOBIN, Auteur ; J. GREEN, Auteur . - p.26. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 8-1 (December 2016) . - p.26 Mots-clés : Autism spectrum disorder  Neurofibromatosis type 1  Sex bias  Syndromic autism Index. décimale : PER Périodiques Résumé : BACKGROUND: Despite extensive literature, little is known about the mechanisms underlying sex bias in autism spectrum disorder (ASD). This study investigates the sex differences in ASD associated with neurofibromatosis type 1, a single-gene model of syndromic autism. METHODS: We analysed data from n = 194 children aged 4-16 years with neurofibromatosis type 1. Sex differences were evaluated across the Autism Diagnostic Interview-Revised (ADI-R), Autism Diagnostic Observation Schedule (ADOS), verbal IQ, Social Responsiveness Scale (SRS) and Conners questionnaires. RESULTS: There was 2.68:1 male:female ratio in children meeting ASD criteria on the deep phenotyping measures. On symptom profile, males with neurofibromatosis type 1 (NF1) + ASD were more impaired on reciprocal social interaction and communication domains of the ADI-R but we found no differences on the restricted, repetitive behaviours (RRBs) domain of the ADI-R and no differences on the social on the ADOS. NF1 ASD males and females were comparable on verbal IQ, and the inattention/hyperactivity domains of the Conners questionnaire. CONCLUSIONS: There is a significant male bias in the prevalence of ASD in NF1. The phenotypic profile of NF1 + ASD cases includes greater social communication impairment in males. We discuss the implications of our findings and the rationale for using NF1 as a model for investigating sex bias in idiopathic ASD. En ligne : http://dx.doi.org/10.1186/s11689-016-9159-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=349

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