Brief Report: Relationship Between ADOS-2, Module 4 Calibrated Severity Scores (CSS) and Social and Non-Social Standardized Assessment Measures in Adult Males with Autism Spectrum Disorder (ASD) / Michael J. MORRIER in Journal of Autism and Developmental Disorders, 47-12 (December 2017)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 47-12 (December 2017) . - p.4018-4024 Titre : Brief Report: Relationship Between ADOS-2, Module 4 Calibrated Severity Scores (CSS) and Social and Non-Social Standardized Assessment Measures in Adult Males with Autism Spectrum Disorder (ASD) Type de document : texte imprimé Auteurs : Michael J. MORRIER, Auteur ; Opal Y. OUSLEY, Auteur ; Gabriella A. CACERES-GAMUNDI, Auteur ; Matthew J. SEGALL, Auteur ; Joseph F. CUBELLS, Auteur ; Larry J. YOUNG, Auteur ; Elissar ANDARI, Auteur Année de publication : 2017 Article en page(s) : p.4018-4024 Langues : Anglais (eng) Mots-clés : ADOS-2, Module 4  Aq  Calibrated severity scores  Scl-90  Srs-2  Verbal intellectual quotient Index. décimale : PER Périodiques Résumé : The ADOS-2 Modules 1-3 now include a standardized calibrated severity score (CSS) from 1 to 10 based on the overall total raw score. Subsequent research published CSS for Module 4 (Hus, Lord, Journal of Autism and Developmental Disorders 44(8):1996-2012, 2014); however more research is needed to examine the psychometric properties of this CSS. Forty males with ASD completed an assessment battery consisting of ADOS-2 Module 4 and other clinical measures assessing core ASD symptomology and comorbidity. Pearson correlation analyses found that CSS did not correlate with measures that assessed core social deficits of ASD or general psychiatric co-morbidity, but CSS did correlate negatively with intellectual quotient. These findings provide information on the limitations and relevance of CSS to be taken into account in future clinical evaluations of ASD. En ligne : http://dx.doi.org/10.1007/s10803-017-3293-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=326 [article] Brief Report: Relationship Between ADOS-2, Module 4 Calibrated Severity Scores (CSS) and Social and Non-Social Standardized Assessment Measures in Adult Males with Autism Spectrum Disorder (ASD) [texte imprimé] / Michael J. MORRIER, Auteur ; Opal Y. OUSLEY, Auteur ; Gabriella A. CACERES-GAMUNDI, Auteur ; Matthew J. SEGALL, Auteur ; Joseph F. CUBELLS, Auteur ; Larry J. YOUNG, Auteur ; Elissar ANDARI, Auteur . - 2017 . - p.4018-4024. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 47-12 (December 2017) . - p.4018-4024 Mots-clés : ADOS-2, Module 4  Aq  Calibrated severity scores  Scl-90  Srs-2  Verbal intellectual quotient Index. décimale : PER Périodiques Résumé : The ADOS-2 Modules 1-3 now include a standardized calibrated severity score (CSS) from 1 to 10 based on the overall total raw score. Subsequent research published CSS for Module 4 (Hus, Lord, Journal of Autism and Developmental Disorders 44(8):1996-2012, 2014); however more research is needed to examine the psychometric properties of this CSS. Forty males with ASD completed an assessment battery consisting of ADOS-2 Module 4 and other clinical measures assessing core ASD symptomology and comorbidity. Pearson correlation analyses found that CSS did not correlate with measures that assessed core social deficits of ASD or general psychiatric co-morbidity, but CSS did correlate negatively with intellectual quotient. These findings provide information on the limitations and relevance of CSS to be taken into account in future clinical evaluations of ASD. En ligne : http://dx.doi.org/10.1007/s10803-017-3293-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=326

School-age social behavior and pragmatic language ability in children with prenatal serotonin reuptake inhibitor exposure / Erica L. SMEARMAN in Development and Psychopathology, 32-1 (February 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-1 (February 2020) . - p.21-30 Titre : School-age social behavior and pragmatic language ability in children with prenatal serotonin reuptake inhibitor exposure Type de document : texte imprimé Auteurs : Erica L. SMEARMAN, Auteur ; Cassandra L. HENDRIX, Auteur ; Dominika A. WINIARSKI, Auteur ; Katrina C. JOHNSON, Auteur ; Alicia K. SMITH, Auteur ; Opal Y. OUSLEY, Auteur ; Zachary N. STOWE, Auteur ; D. Jeffrey NEWPORT, Auteur ; Patricia A. BRENNAN, Auteur Article en page(s) : p.21-30 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder  language  neurodevelopment  prenatal exposure  serotonin Index. décimale : PER Périodiques Résumé : Studies examining associations between fetal serotonin reuptake inhibitor (SRI) exposure and child autism spectrum disorder (ASD) diagnoses or delayed language remain mixed and rarely prospectively follow children or employ gold-standard assessments. We prospectively followed a cohort of mother-child dyads from pregnancy through early elementary school (N = 178), and obtained maternal and alternate-caregiver ratings of behaviors related to ASD (N = 137), as well as direct, gold-standard assessments of child ASD symptoms and pragmatic language among dyads who experienced prenatal depression and either took SRIs or were medication free during pregnancy (N = 44). Prenatal SRI exposure was related to maternal ratings of ASD-related behaviors (beta = 0.24 95% confidence interval; CI [0.07, 0.48]), and, among boys, alternative caregiver ratings (males-only beta = 0.28 95% CI [0.02, 0.55], females-only beta = -0.21 95% CI [-0.63, 0.08]). However, results of our direct assessments suggest an association between SRI exposure and reduced pragmatic language scores (beta = -0.27, 95% CI [-0.53, -0.01], but not ASD (Autism Diagnostic Observation Schedule beta = 0.14 95% CI [-0.15, 0.41]; Social Responsiveness Scale beta = 0.08 95% CI [-0.25, 0.40]). These discrepancies point to issues regarding how ASD is assessed, and the possibility that SRIs may be more strongly associated with language or other broader behaviors that coincide with ASD. Larger prospective studies that incorporate thorough, gold-standard assessments of ASD, language, and other ASD-related behaviors are needed. En ligne : http://dx.doi.org/10.1017/s0954579418001372 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=415 [article] School-age social behavior and pragmatic language ability in children with prenatal serotonin reuptake inhibitor exposure [texte imprimé] / Erica L. SMEARMAN, Auteur ; Cassandra L. HENDRIX, Auteur ; Dominika A. WINIARSKI, Auteur ; Katrina C. JOHNSON, Auteur ; Alicia K. SMITH, Auteur ; Opal Y. OUSLEY, Auteur ; Zachary N. STOWE, Auteur ; D. Jeffrey NEWPORT, Auteur ; Patricia A. BRENNAN, Auteur . - p.21-30. Langues : Anglais (eng) in Development and Psychopathology > 32-1 (February 2020) . - p.21-30 Mots-clés : Autism Spectrum Disorder  language  neurodevelopment  prenatal exposure  serotonin Index. décimale : PER Périodiques Résumé : Studies examining associations between fetal serotonin reuptake inhibitor (SRI) exposure and child autism spectrum disorder (ASD) diagnoses or delayed language remain mixed and rarely prospectively follow children or employ gold-standard assessments. We prospectively followed a cohort of mother-child dyads from pregnancy through early elementary school (N = 178), and obtained maternal and alternate-caregiver ratings of behaviors related to ASD (N = 137), as well as direct, gold-standard assessments of child ASD symptoms and pragmatic language among dyads who experienced prenatal depression and either took SRIs or were medication free during pregnancy (N = 44). Prenatal SRI exposure was related to maternal ratings of ASD-related behaviors (beta = 0.24 95% confidence interval; CI [0.07, 0.48]), and, among boys, alternative caregiver ratings (males-only beta = 0.28 95% CI [0.02, 0.55], females-only beta = -0.21 95% CI [-0.63, 0.08]). However, results of our direct assessments suggest an association between SRI exposure and reduced pragmatic language scores (beta = -0.27, 95% CI [-0.53, -0.01], but not ASD (Autism Diagnostic Observation Schedule beta = 0.14 95% CI [-0.15, 0.41]; Social Responsiveness Scale beta = 0.08 95% CI [-0.25, 0.40]). These discrepancies point to issues regarding how ASD is assessed, and the possibility that SRIs may be more strongly associated with language or other broader behaviors that coincide with ASD. Larger prospective studies that incorporate thorough, gold-standard assessments of ASD, language, and other ASD-related behaviors are needed. En ligne : http://dx.doi.org/10.1017/s0954579418001372 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=415

Toward better outcome measurement for insomnia in children with autism spectrum disorder / Luc LECAVALIER ; Michael C. EDWARDS ; Megan L. WENZELL ; Leah M. BARTO ; Arielle MULLIGAN ; Auscia T. WILLIAMS ; Opal Y. OUSLEY ; Cynthia B. SINHA ; Christopher A. TAYLOR ; Soo Youn KIM ; Laura M. JOHNSON ; Scott E. GILLESPIE ; Cynthia JOHNSON in Autism, 28-12 (December 2024)  

Public ISBD [article]  inAutism > 28-12 (December 2024) . - p.3131-3142 Titre : Toward better outcome measurement for insomnia in children with autism spectrum disorder Type de document : texte imprimé Auteurs : Luc LECAVALIER, Auteur ; Michael C. EDWARDS, Auteur ; Megan L. WENZELL, Auteur ; Leah M. BARTO, Auteur ; Arielle MULLIGAN, Auteur ; Auscia T. WILLIAMS, Auteur ; Opal Y. OUSLEY, Auteur ; Cynthia B. SINHA, Auteur ; Christopher A. TAYLOR, Auteur ; Soo Youn KIM, Auteur ; Laura M. JOHNSON, Auteur ; Scott E. GILLESPIE, Auteur ; Cynthia JOHNSON, Auteur Article en page(s) : p.3131-3142 Langues : Anglais (eng) Mots-clés : autism  children  insomnia  outcome measure Index. décimale : PER Périodiques Résumé : This report presents a new parent-rated outcome measure of insomnia for children with autism spectrum disorder. Parents of 1185 children with autism spectrum disorder (aged 3-12; 80.3% male) completed the first draft of the measure online. Factor and item response theory analyses reduced the set of 40 items to the final 21-item Pediatric Insomnia Autism Rating Scale. In this online sample, Pediatric Insomnia Autism Rating Scale mean was 21.8+15.0 (range 0-63; coefficient alpha = 0.94). Item response theory results indicated excellent reliability across a range of scores. Next, we conducted a telehealth assessment of 134 children with autism spectrum disorder (aged 3-12; 73% male). In this clinical sample, Pediatric Insomnia Autism Rating Scale mean was 28.9+14.62 (range 0-61; coefficient alpha = 0.93). Pearson correlations of Pediatric Insomnia Autism Rating Scale with the PROMIS Sleep Disturbance and the modified Children s Sleep Habits Questionnaire was 0.74 for each. This was significantly higher than correlations of parent-rated disruptive behavior, hyperactivity, repetitive behavior, and anxiety measures (range 0.29-0.59)-supporting convergent and divergent validity. Parents of 63 children completed the Pediatric Insomnia Autism Rating Scale three times over 4 weeks. Intraclass correlation was excellent (0.88) over three time points. Pediatric Insomnia Autism Rating Scale is a valid dimensional measure of insomnia in autistic children that produces reliable scores. Lay Abstract Insomnia, trouble falling asleep or staying asleep, is common in autistic children. In a previous report, we described the results of focus groups with parents of autistic children toward the development of the Pediatric Autism Insomnia Rating Scale. In this article, we report on the steps taken to complete the Pediatric Autism Insomnia Rating Scale. With help from the Simons Foundation registry, we collected information from parents on 1185 children with autism spectrum disorder to test the new measure. These results were evaluated using standard statistical methods such as factor analysis. To confirm the validity of the new measure, we enrolled a separate sample of 134 autistic children for a detailed assessment by video conference. This step showed that the Pediatric Autism Insomnia Rating Scale is clearly measuring symptoms of insomnia in children with autism spectrum disorder and not related problems such as hyperactivity, repetitive behavior, or anxiety. We also showed that the total score on the Pediatric Autism Insomnia Rating Scale is stable when repeated over a brief period of time. This is important because a measure that is not stable over a brief period of time would not be suitable as an outcome measure. In summary, the Pediatric Autism Insomnia Rating Scale is a brief and valid measure of insomnia in children with autism spectrum disorder that provides reliable scores. En ligne : https://dx.doi.org/10.1177/13623613241255814 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=543 [article] Toward better outcome measurement for insomnia in children with autism spectrum disorder [texte imprimé] / Luc LECAVALIER, Auteur ; Michael C. EDWARDS, Auteur ; Megan L. WENZELL, Auteur ; Leah M. BARTO, Auteur ; Arielle MULLIGAN, Auteur ; Auscia T. WILLIAMS, Auteur ; Opal Y. OUSLEY, Auteur ; Cynthia B. SINHA, Auteur ; Christopher A. TAYLOR, Auteur ; Soo Youn KIM, Auteur ; Laura M. JOHNSON, Auteur ; Scott E. GILLESPIE, Auteur ; Cynthia JOHNSON, Auteur . - p.3131-3142. Langues : Anglais (eng) in Autism > 28-12 (December 2024) . - p.3131-3142 Mots-clés : autism  children  insomnia  outcome measure Index. décimale : PER Périodiques Résumé : This report presents a new parent-rated outcome measure of insomnia for children with autism spectrum disorder. Parents of 1185 children with autism spectrum disorder (aged 3-12; 80.3% male) completed the first draft of the measure online. Factor and item response theory analyses reduced the set of 40 items to the final 21-item Pediatric Insomnia Autism Rating Scale. In this online sample, Pediatric Insomnia Autism Rating Scale mean was 21.8+15.0 (range 0-63; coefficient alpha = 0.94). Item response theory results indicated excellent reliability across a range of scores. Next, we conducted a telehealth assessment of 134 children with autism spectrum disorder (aged 3-12; 73% male). In this clinical sample, Pediatric Insomnia Autism Rating Scale mean was 28.9+14.62 (range 0-61; coefficient alpha = 0.93). Pearson correlations of Pediatric Insomnia Autism Rating Scale with the PROMIS Sleep Disturbance and the modified Children s Sleep Habits Questionnaire was 0.74 for each. This was significantly higher than correlations of parent-rated disruptive behavior, hyperactivity, repetitive behavior, and anxiety measures (range 0.29-0.59)-supporting convergent and divergent validity. Parents of 63 children completed the Pediatric Insomnia Autism Rating Scale three times over 4 weeks. Intraclass correlation was excellent (0.88) over three time points. Pediatric Insomnia Autism Rating Scale is a valid dimensional measure of insomnia in autistic children that produces reliable scores. Lay Abstract Insomnia, trouble falling asleep or staying asleep, is common in autistic children. In a previous report, we described the results of focus groups with parents of autistic children toward the development of the Pediatric Autism Insomnia Rating Scale. In this article, we report on the steps taken to complete the Pediatric Autism Insomnia Rating Scale. With help from the Simons Foundation registry, we collected information from parents on 1185 children with autism spectrum disorder to test the new measure. These results were evaluated using standard statistical methods such as factor analysis. To confirm the validity of the new measure, we enrolled a separate sample of 134 autistic children for a detailed assessment by video conference. This step showed that the Pediatric Autism Insomnia Rating Scale is clearly measuring symptoms of insomnia in children with autism spectrum disorder and not related problems such as hyperactivity, repetitive behavior, or anxiety. We also showed that the total score on the Pediatric Autism Insomnia Rating Scale is stable when repeated over a brief period of time. This is important because a measure that is not stable over a brief period of time would not be suitable as an outcome measure. In summary, the Pediatric Autism Insomnia Rating Scale is a brief and valid measure of insomnia in children with autism spectrum disorder that provides reliable scores. En ligne : https://dx.doi.org/10.1177/13623613241255814 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=543

Validation of an Enhanced Telehealth Platform for Toddlers at Increased Likelihood for a Diagnosis of Autism Spectrum Disorder (ASD) / Michael J. MORRIER in Journal of Autism and Developmental Disorders, 54-11 (November)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 54-11 (November) . - p.4019-4033 Titre : Validation of an Enhanced Telehealth Platform for Toddlers at Increased Likelihood for a Diagnosis of Autism Spectrum Disorder (ASD) Type de document : texte imprimé Auteurs : Michael J. MORRIER, Auteur ; Allison J. SCHWARTZ, Auteur ; Catherine E. RICE, Auteur ; Amanda PLATNER, Auteur ; Opal Y. OUSLEY, Auteur ; Sara KASSEM, Auteur ; Ashwin V. KRISHNAN, Auteur ; Catherine LORD, Auteur ; Christopher J. SMITH, Auteur ; Ron OBERLEITNER, Auteur Article en page(s) : p.4019-4033 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Use of telehealth assessments for toddlers at increased likelihood of autism spectrum disorder (ASD) began prior to the global COVID-19 pandemic; however, the value of telehealth assessments as an alternative to in-person assessment (IPA) became clearer during the pandemic. The Naturalistic Observation Diagnosis Assessment (NODA?), previously demonstrated as a valid and reliable tool to evaluate asynchronous behaviors for early diagnosis, was enhanced to add synchronous collection of behaviors to assist clinicians in making a differential diagnosis of ASD. This study was conducted to validate the information gathered through NODA-Enhanced (NODA-E?) as compared to a gold standard IPA. Forty-nine toddlers aged 16.0-32.1 months of age, recruited through community pediatric offices and a tertiary ASD clinic, participated in both NODA-E and IPA assessments. There was high agreement between the two assessment protocols for overall diagnosis (46 of 49 cases; 93.6%; ? = .878), specific diagnostic criteria for social communication and social interaction (SCI; range 95.9-98%; ? = .918-.959), and for two of four criteria specified for restricted and repetitive behaviors (RRB; range 87.8-98%; ? = .755 and .959). There was lower agreement for two subcategories of RRBs (range 65.3-67.3%; ? = .306 and .347). NODA-E is a tool that can assist clinicians in making reliable and valid early ASD diagnoses using both asynchronous and synchronous information gathered via telehealth and offers an additional tool within a clinician s assessment toolbox. En ligne : https://doi.org/10.1007/s10803-023-06116-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=536 [article] Validation of an Enhanced Telehealth Platform for Toddlers at Increased Likelihood for a Diagnosis of Autism Spectrum Disorder (ASD) [texte imprimé] / Michael J. MORRIER, Auteur ; Allison J. SCHWARTZ, Auteur ; Catherine E. RICE, Auteur ; Amanda PLATNER, Auteur ; Opal Y. OUSLEY, Auteur ; Sara KASSEM, Auteur ; Ashwin V. KRISHNAN, Auteur ; Catherine LORD, Auteur ; Christopher J. SMITH, Auteur ; Ron OBERLEITNER, Auteur . - p.4019-4033. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 54-11 (November) . - p.4019-4033 Index. décimale : PER Périodiques Résumé : Use of telehealth assessments for toddlers at increased likelihood of autism spectrum disorder (ASD) began prior to the global COVID-19 pandemic; however, the value of telehealth assessments as an alternative to in-person assessment (IPA) became clearer during the pandemic. The Naturalistic Observation Diagnosis Assessment (NODA?), previously demonstrated as a valid and reliable tool to evaluate asynchronous behaviors for early diagnosis, was enhanced to add synchronous collection of behaviors to assist clinicians in making a differential diagnosis of ASD. This study was conducted to validate the information gathered through NODA-Enhanced (NODA-E?) as compared to a gold standard IPA. Forty-nine toddlers aged 16.0-32.1 months of age, recruited through community pediatric offices and a tertiary ASD clinic, participated in both NODA-E and IPA assessments. There was high agreement between the two assessment protocols for overall diagnosis (46 of 49 cases; 93.6%; ? = .878), specific diagnostic criteria for social communication and social interaction (SCI; range 95.9-98%; ? = .918-.959), and for two of four criteria specified for restricted and repetitive behaviors (RRB; range 87.8-98%; ? = .755 and .959). There was lower agreement for two subcategories of RRBs (range 65.3-67.3%; ? = .306 and .347). NODA-E is a tool that can assist clinicians in making reliable and valid early ASD diagnoses using both asynchronous and synchronous information gathered via telehealth and offers an additional tool within a clinician s assessment toolbox. En ligne : https://doi.org/10.1007/s10803-023-06116-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=536

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