Autism spectrum disorder and vitamin D status: A cross-sectional study of children in a developing country in Southeast Asia / Subhashini JAYANATH in Research in Autism Spectrum Disorders, 84 (June 2021)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 84 (June 2021) . - 101786 Titre : Autism spectrum disorder and vitamin D status: A cross-sectional study of children in a developing country in Southeast Asia Type de document : Texte imprimé et/ou numérique Auteurs : Subhashini JAYANATH, Auteur ; Choong Yi FONG, Auteur ; Rajini SARVANANTHAN, Auteur Article en page(s) : 101786 Langues : Anglais (eng) Mots-clés : Autism  Vitamin D  Children  Childhood Autism Rating Scale  Aberrant Behaviour Checklist Index. décimale : PER Périodiques Résumé : Background Determine the prevalence and risk factors of vitamin D deficiency (<35?nmol/L) in children with autism spectrum disorder (ASD); and explore the association between vitamin D deficiency with ASD severity and behavioural symptoms. Method Cross-sectional study of children with ASD at a tertiary hospital. Children with vitamin D deficiency (<35.0?nmol/L) were treated (1200IU cholecalciferol, daily for 3 months). ASD severity was determined via the Childhood Autism Rating Scale, 2nd Edition (CARS-2); and behavioural symptoms via the Aberrant Behaviour Checklist, 2nd Edition (ABC-2). Scores were compared between the vitamin D deficient and non-deficient groups. Results There were 103 participants (85.4 % male). Mean age: 6.2 years (SD?=?2.4), 19 % were vitamin D deficient and 42 % were insufficient. Mean vitamin D concentration was 45.8?nmol/L (SD?=?13.5). Female gender was significantly associated with vitamin D deficiency (OR 5.05, 95 % CI: 1.56, 16.31, p?=?0.007). Post-vitamin D treatment, there was a significant reduction in CARS-2 scores (p? En ligne : https://doi.org/10.1016/j.rasd.2021.101786 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=446 [article] Autism spectrum disorder and vitamin D status: A cross-sectional study of children in a developing country in Southeast Asia [Texte imprimé et/ou numérique] / Subhashini JAYANATH, Auteur ; Choong Yi FONG, Auteur ; Rajini SARVANANTHAN, Auteur . - 101786. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 84 (June 2021) . - 101786 Mots-clés : Autism  Vitamin D  Children  Childhood Autism Rating Scale  Aberrant Behaviour Checklist Index. décimale : PER Périodiques Résumé : Background Determine the prevalence and risk factors of vitamin D deficiency (<35?nmol/L) in children with autism spectrum disorder (ASD); and explore the association between vitamin D deficiency with ASD severity and behavioural symptoms. Method Cross-sectional study of children with ASD at a tertiary hospital. Children with vitamin D deficiency (<35.0?nmol/L) were treated (1200IU cholecalciferol, daily for 3 months). ASD severity was determined via the Childhood Autism Rating Scale, 2nd Edition (CARS-2); and behavioural symptoms via the Aberrant Behaviour Checklist, 2nd Edition (ABC-2). Scores were compared between the vitamin D deficient and non-deficient groups. Results There were 103 participants (85.4 % male). Mean age: 6.2 years (SD?=?2.4), 19 % were vitamin D deficient and 42 % were insufficient. Mean vitamin D concentration was 45.8?nmol/L (SD?=?13.5). Female gender was significantly associated with vitamin D deficiency (OR 5.05, 95 % CI: 1.56, 16.31, p?=?0.007). Post-vitamin D treatment, there was a significant reduction in CARS-2 scores (p? En ligne : https://doi.org/10.1016/j.rasd.2021.101786 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=446

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