Evaluating a treatment selection approach for online single-session interventions for adolescent depression / Michael C. MULLARKEY ; Jenna Y. SUNG ; Kathryn R. FOX ; Jessica L. SCHLEIDER in Journal of Child Psychology and Psychiatry, 64-12 (December 2023)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 64-12 (December 2023) . - p.1679-1688 Titre : Evaluating a treatment selection approach for online single-session interventions for adolescent depression Type de document : Texte imprimé et/ou numérique Auteurs : Michael C. MULLARKEY, Auteur ; Jenna Y. SUNG, Auteur ; Kathryn R. FOX, Auteur ; Jessica L. SCHLEIDER, Auteur Article en page(s) : p.1679-1688 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background The question "what works for whom' is essential to mental health research, as matching individuals to the treatment best suited to their needs has the potential to maximize the effectiveness of existing approaches. Digitally administered single-session interventions (SSIs) are effective means of reducing depressive symptoms in adolescence, with potential for rapid, large-scale implementation. However, little is known about which SSIs work best for different adolescents. Objective We created and tested a treatment selection algorithm for use with two SSIs targeting depression in high-symptom adolescents from across the United States. Methods Using data from a large-scale RCT comparing two evidence-based SSIs (N=996; ClinicalTrials.gov: NCT04634903), we utilized a Personalized Advantage Index approach to create and evaluate a treatment-matching algorithm for these interventions. The two interventions were Project Personality (PP; N=482), an intervention teaching that traits and symptoms are malleable (a "growth mindset'), and the Action Brings Change Project (ABC; N=514), a behavioral activation intervention. Results Results indicated no significant difference in 3-month depression outcomes between participants assigned to their matched intervention and those assigned to their nonmatched intervention. The relationship between predicted response to intervention (RTI) and observed RTI was weak for both interventions (r=.39 for PP, r=.24 for ABC). Moreover, the correlation between a participants' predicted RTI for PP and their predicted RTI for ABC was very high (r=.79). Conclusions The utility of treatment selection approaches for SSIs targeting adolescent depression appears limited. Results suggest that both (a) predicting RTI for SSIs is relatively challenging, and (b) the factors that predict RTI for SSIs are similar regardless of the content of the intervention. Given their overall effectiveness and their low-intensity, low-cost nature, increasing youths' access to both digital SSIs may carry more public health utility than additional treatment-matching efforts. En ligne : https://doi.org/10.1111/jcpp.13822 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 [article] Evaluating a treatment selection approach for online single-session interventions for adolescent depression [Texte imprimé et/ou numérique] / Michael C. MULLARKEY, Auteur ; Jenna Y. SUNG, Auteur ; Kathryn R. FOX, Auteur ; Jessica L. SCHLEIDER, Auteur . - p.1679-1688. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 64-12 (December 2023) . - p.1679-1688 Index. décimale : PER Périodiques Résumé : Background The question "what works for whom' is essential to mental health research, as matching individuals to the treatment best suited to their needs has the potential to maximize the effectiveness of existing approaches. Digitally administered single-session interventions (SSIs) are effective means of reducing depressive symptoms in adolescence, with potential for rapid, large-scale implementation. However, little is known about which SSIs work best for different adolescents. Objective We created and tested a treatment selection algorithm for use with two SSIs targeting depression in high-symptom adolescents from across the United States. Methods Using data from a large-scale RCT comparing two evidence-based SSIs (N=996; ClinicalTrials.gov: NCT04634903), we utilized a Personalized Advantage Index approach to create and evaluate a treatment-matching algorithm for these interventions. The two interventions were Project Personality (PP; N=482), an intervention teaching that traits and symptoms are malleable (a "growth mindset'), and the Action Brings Change Project (ABC; N=514), a behavioral activation intervention. Results Results indicated no significant difference in 3-month depression outcomes between participants assigned to their matched intervention and those assigned to their nonmatched intervention. The relationship between predicted response to intervention (RTI) and observed RTI was weak for both interventions (r=.39 for PP, r=.24 for ABC). Moreover, the correlation between a participants' predicted RTI for PP and their predicted RTI for ABC was very high (r=.79). Conclusions The utility of treatment selection approaches for SSIs targeting adolescent depression appears limited. Results suggest that both (a) predicting RTI for SSIs is relatively challenging, and (b) the factors that predict RTI for SSIs are similar regardless of the content of the intervention. Given their overall effectiveness and their low-intensity, low-cost nature, increasing youths' access to both digital SSIs may carry more public health utility than additional treatment-matching efforts. En ligne : https://doi.org/10.1111/jcpp.13822 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517

The transdiagnostic origins of anxiety and depression during the pediatric period: Linking NIMH research domain criteria (RDoC) constructs to ecological systems / Jenalee R. DOOM in Development and Psychopathology, 33-5 (December 2021)  

Public ISBD [article]  inDevelopment and Psychopathology > 33-5 (December 2021) . - p.1599-1619 Titre : The transdiagnostic origins of anxiety and depression during the pediatric period: Linking NIMH research domain criteria (RDoC) constructs to ecological systems Type de document : Texte imprimé et/ou numérique Auteurs : Jenalee R. DOOM, Auteur ; Michelle ROZENMAN, Auteur ; Kathryn R. FOX, Auteur ; Tiffany PHU, Auteur ; Anni R. SUBAR, Auteur ; Deborah SEOK, Auteur ; Kenia M. RIVERA, Auteur Article en page(s) : p.1599-1619 Langues : Anglais (eng) Mots-clés : anxiety  depression  ecological systems theory  RDoC  youth Index. décimale : PER Périodiques Résumé : In the last decade, an abundance of research has utilized the National Institute of Mental Health (NIMH) research domain criteria (RDoC) framework to examine mechanisms underlying anxiety and depression in youth. However, relatively little work has examined how these mechanistic intrapersonal processes intersect with context during childhood and adolescence. The current paper covers reviews and meta-analyses that have linked RDoC-relevant constructs to ecological systems in internalizing problems in youth. Specifically, cognitive, biological, and affective factors within the RDoC framework were examined. Based on these reviews and some of the original empirical research they cover, we highlight the integral role of ecological factors to the RDoC framework in predicting onset and maintenance of internalizing problems in youth. Specific recommendations are provided for researchers using the RDoC framework to inform future research integrating ecological systems and development. We advocate for future research and research funding to focus on better integration of the environment and development into the RDoC framework. En ligne : http://dx.doi.org/10.1017/S0954579421000559 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457 [article] The transdiagnostic origins of anxiety and depression during the pediatric period: Linking NIMH research domain criteria (RDoC) constructs to ecological systems [Texte imprimé et/ou numérique] / Jenalee R. DOOM, Auteur ; Michelle ROZENMAN, Auteur ; Kathryn R. FOX, Auteur ; Tiffany PHU, Auteur ; Anni R. SUBAR, Auteur ; Deborah SEOK, Auteur ; Kenia M. RIVERA, Auteur . - p.1599-1619. Langues : Anglais (eng) in Development and Psychopathology > 33-5 (December 2021) . - p.1599-1619 Mots-clés : anxiety  depression  ecological systems theory  RDoC  youth Index. décimale : PER Périodiques Résumé : In the last decade, an abundance of research has utilized the National Institute of Mental Health (NIMH) research domain criteria (RDoC) framework to examine mechanisms underlying anxiety and depression in youth. However, relatively little work has examined how these mechanistic intrapersonal processes intersect with context during childhood and adolescence. The current paper covers reviews and meta-analyses that have linked RDoC-relevant constructs to ecological systems in internalizing problems in youth. Specifically, cognitive, biological, and affective factors within the RDoC framework were examined. Based on these reviews and some of the original empirical research they cover, we highlight the integral role of ecological factors to the RDoC framework in predicting onset and maintenance of internalizing problems in youth. Specific recommendations are provided for researchers using the RDoC framework to inform future research integrating ecological systems and development. We advocate for future research and research funding to focus on better integration of the environment and development into the RDoC framework. En ligne : http://dx.doi.org/10.1017/S0954579421000559 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457

Timing of childhood adversities and self-injurious thoughts and behaviors in adolescence / Samantha J. NORTH in Development and Psychopathology, 35-1 (February 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-1 (February 2023) . - p.410-420 Titre : Timing of childhood adversities and self-injurious thoughts and behaviors in adolescence Type de document : Texte imprimé et/ou numérique Auteurs : Samantha J. NORTH, Auteur ; Kathryn R. FOX, Auteur ; Jenalee R. DOOM, Auteur Article en page(s) : p.410-420 Langues : Anglais (eng) Mots-clés : adolescent  childhood adversity  LONGSCAN  suicide Index. décimale : PER Périodiques Résumé : Greater childhood adversity predicts a higher likelihood of later self-injurious thoughts and behaviors (SITB). There is little research focused on whether the timing of childhood adversity predicts SITB. The current research examined whether the timing of childhood adversity predicted parent- and youth-reported SITB at age 12 and 16 years in the Longitudinal Studies of Child Abuse and Neglect (LONGSCAN) cohort (n = 970). We found that greater adversity at age 11-12 years consistently predicted SITB at age 12 years, while greater adversity at age 13-14 years consistently predicted SITB at age 16 years. These findings suggest there may be sensitive periods during which adversity may be more likely to lead to adolescent SITB, which can inform prevention and treatment. En ligne : https://doi.org/10.1017/S0954579421000808 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=500 [article] Timing of childhood adversities and self-injurious thoughts and behaviors in adolescence [Texte imprimé et/ou numérique] / Samantha J. NORTH, Auteur ; Kathryn R. FOX, Auteur ; Jenalee R. DOOM, Auteur . - p.410-420. Langues : Anglais (eng) in Development and Psychopathology > 35-1 (February 2023) . - p.410-420 Mots-clés : adolescent  childhood adversity  LONGSCAN  suicide Index. décimale : PER Périodiques Résumé : Greater childhood adversity predicts a higher likelihood of later self-injurious thoughts and behaviors (SITB). There is little research focused on whether the timing of childhood adversity predicts SITB. The current research examined whether the timing of childhood adversity predicted parent- and youth-reported SITB at age 12 and 16 years in the Longitudinal Studies of Child Abuse and Neglect (LONGSCAN) cohort (n = 970). We found that greater adversity at age 11-12 years consistently predicted SITB at age 12 years, while greater adversity at age 13-14 years consistently predicted SITB at age 16 years. These findings suggest there may be sensitive periods during which adversity may be more likely to lead to adolescent SITB, which can inform prevention and treatment. En ligne : https://doi.org/10.1017/S0954579421000808 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=500

Type, content, and triggers for self-injurious thoughts and behaviors in autistic youth and their disclosure to caregivers / Alex RUBIN ; Kathryn R. FOX ; Darren HEDLEY ; Alexandra H BETTIS in Autism, 29-6 (June 2025)  

Public ISBD [article]  inAutism > 29-6 (June 2025) . - p.1627-1635 Titre : Type, content, and triggers for self-injurious thoughts and behaviors in autistic youth and their disclosure to caregivers Type de document : Texte imprimé et/ou numérique Auteurs : Alex RUBIN, Auteur ; Kathryn R. FOX, Auteur ; Darren HEDLEY, Auteur ; Alexandra H BETTIS, Auteur Article en page(s) : p.1627-1635 Langues : Anglais (eng) Mots-clés : adolescents  autism  disclosure  self-injurious thoughts and behaviors  suicide Index. décimale : PER Périodiques Résumé : Rates of self-injurious thoughts and behaviors are elevated among autistic youth, yet research is limited to caregiver report or single-item questionnaires. Investigation of specific suicidal thoughts, triggers, and disclosure is needed to improve risk assessment and interventions. The current study characterized self-injurious thoughts and behaviors in a sample of autistic youth without intellectual disability presenting for outpatient psychological services. The Columbia-Suicide Severity Rating Scale and qualitative follow-up questions were administered to 103 autistic youth (10-17?years of age). Most autistic youth (n = 86; 83.5%) reported lifetime suicidal thoughts. Suicide thought content most commonly included abstract thoughts of dying/suicide (n = 20; 23.3%) and death by cutting (n = 13; 15.1%). Half of youth experiencing suicidal thoughts (n = 43; 50.0%) denied disclosure to their caregiver. Nearly one in four youth attempted suicide (n = 25; 24.3%), and some youth (n = 16; 15.5%) sought help from caregivers to prevent an attempt. Sadness/depression and bullying/teasing were the most commonly reported triggers of suicidal behaviors. Among autistic youth with lifetime nonsuicidal self-injury (n = 52; 50.5%), head hitting (n = 28; 45.2%) and cutting (n = 20; 32.3%) were the most reported types. Findings underscore the importance of targeted prevention and intervention to address self-injurious thoughts and behaviors in autistic youth and continued research to understand barriers and modifiable factors to facilitate self-injurious thoughts and behaviors disclosure.Lay abstract Self-injurious thoughts and behaviors are high among autistic youth, yet research most often relies on caregiver reports and does not include youth perspectives. Relatedly, specific characteristics of self-injurious thoughts and behaviors (e.g. type of behavior, thought content, triggers), and choices to share these thoughts and behaviors with caregivers/parents (or not), have not been studied in autistic youth. With limited information on self-injurious thoughts and behaviors in autistic youth, clinicians and families supporting autistic youth in crisis continue to experience major challenges to best assess and support youth. Therefore, to begin to understand youth perspectives of self-injurious thoughts and behaviors, we administered a self-injurious thoughts and behaviors clinical interview (Columbia-Suicide Severity Rating Scale; C-SSRS) to 103 autistic youth without intellectual disability (10-17?years of age) at a clinic for outpatient mental health services. We added follow-up questions to the interview about suicide to better understand what youth think about when it comes to suicide, what triggers them to feel suicidal, and whether they let their caregiver know about what they are thinking and feeling. Results show that most autistic youth reported suicidal thoughts at some point in their life (n = 86; 83.5%), with thoughts of dying/suicide (n = 20; 23.3%) and death by cutting (n = 13; 15.1%) as common thought content. Half of youth experiencing suicidal thoughts (n = 43; 50.0%) did not share this with their caregiver. Nearly one in four youth had attempted suicide at some point in their life (n = 25; 24.3%), while some youth (n = 16; 15.5%) sought help from caregivers to prevent an attempt. Sadness/depression and bullying/teasing were the most common triggers of suicidal behaviors, while anger/frustration was the leading trigger for nonsuicidal self-injury. Findings can be used to improve current assessment tools and prevention approaches for autistic youth to create better support for autistic youth in crisis. En ligne : https://dx.doi.org/10.1177/13623613241308327 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=558 [article] Type, content, and triggers for self-injurious thoughts and behaviors in autistic youth and their disclosure to caregivers [Texte imprimé et/ou numérique] / Alex RUBIN, Auteur ; Kathryn R. FOX, Auteur ; Darren HEDLEY, Auteur ; Alexandra H BETTIS, Auteur . - p.1627-1635. Langues : Anglais (eng) in Autism > 29-6 (June 2025) . - p.1627-1635 Mots-clés : adolescents  autism  disclosure  self-injurious thoughts and behaviors  suicide Index. décimale : PER Périodiques Résumé : Rates of self-injurious thoughts and behaviors are elevated among autistic youth, yet research is limited to caregiver report or single-item questionnaires. Investigation of specific suicidal thoughts, triggers, and disclosure is needed to improve risk assessment and interventions. The current study characterized self-injurious thoughts and behaviors in a sample of autistic youth without intellectual disability presenting for outpatient psychological services. The Columbia-Suicide Severity Rating Scale and qualitative follow-up questions were administered to 103 autistic youth (10-17?years of age). Most autistic youth (n = 86; 83.5%) reported lifetime suicidal thoughts. Suicide thought content most commonly included abstract thoughts of dying/suicide (n = 20; 23.3%) and death by cutting (n = 13; 15.1%). Half of youth experiencing suicidal thoughts (n = 43; 50.0%) denied disclosure to their caregiver. Nearly one in four youth attempted suicide (n = 25; 24.3%), and some youth (n = 16; 15.5%) sought help from caregivers to prevent an attempt. Sadness/depression and bullying/teasing were the most commonly reported triggers of suicidal behaviors. Among autistic youth with lifetime nonsuicidal self-injury (n = 52; 50.5%), head hitting (n = 28; 45.2%) and cutting (n = 20; 32.3%) were the most reported types. Findings underscore the importance of targeted prevention and intervention to address self-injurious thoughts and behaviors in autistic youth and continued research to understand barriers and modifiable factors to facilitate self-injurious thoughts and behaviors disclosure.Lay abstract Self-injurious thoughts and behaviors are high among autistic youth, yet research most often relies on caregiver reports and does not include youth perspectives. Relatedly, specific characteristics of self-injurious thoughts and behaviors (e.g. type of behavior, thought content, triggers), and choices to share these thoughts and behaviors with caregivers/parents (or not), have not been studied in autistic youth. With limited information on self-injurious thoughts and behaviors in autistic youth, clinicians and families supporting autistic youth in crisis continue to experience major challenges to best assess and support youth. Therefore, to begin to understand youth perspectives of self-injurious thoughts and behaviors, we administered a self-injurious thoughts and behaviors clinical interview (Columbia-Suicide Severity Rating Scale; C-SSRS) to 103 autistic youth without intellectual disability (10-17?years of age) at a clinic for outpatient mental health services. We added follow-up questions to the interview about suicide to better understand what youth think about when it comes to suicide, what triggers them to feel suicidal, and whether they let their caregiver know about what they are thinking and feeling. Results show that most autistic youth reported suicidal thoughts at some point in their life (n = 86; 83.5%), with thoughts of dying/suicide (n = 20; 23.3%) and death by cutting (n = 13; 15.1%) as common thought content. Half of youth experiencing suicidal thoughts (n = 43; 50.0%) did not share this with their caregiver. Nearly one in four youth had attempted suicide at some point in their life (n = 25; 24.3%), while some youth (n = 16; 15.5%) sought help from caregivers to prevent an attempt. Sadness/depression and bullying/teasing were the most common triggers of suicidal behaviors, while anger/frustration was the leading trigger for nonsuicidal self-injury. Findings can be used to improve current assessment tools and prevention approaches for autistic youth to create better support for autistic youth in crisis. En ligne : https://dx.doi.org/10.1177/13623613241308327 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=558

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