Body Mass Index in Male and Female Children with Infantile Autism / Svend Erik MOURIDSEN in Autism, 6-2 (March 2002)  

Public ISBD [article]  inAutism > 6-2 (March 2002) . - p.197-205 Titre : Body Mass Index in Male and Female Children with Infantile Autism Type de document : Texte imprimé et/ou numérique Auteurs : Svend Erik MOURIDSEN, Auteur ; Bente RICH, Auteur ; Torben ISAGER, Auteur Article en page(s) : p.197-205 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Morphometry, the measurement of forms, is an ancient practice. Recently, evidence has grown to support the notion that aberrant neurodevelopment may play a role in the pathophysiology of autism. Is the body, like the brain, affected by abnormal development in these patients? The aim of this study was to evaluate body mass index (BMI) of children with infantile autism, by comparing the BMI of 117 children with infantile autism with the corresponding BMI percentiles in an age- and sex-matched reference population. The BMI distribution of the male, but not female, children with infantile autism was significantly lower than that of the age-matched reference population. There was no evidence that BMI was associated with intelligence or socioeconomic status among children with infantile autism. En ligne : http://dx.doi.org/10.1177/1362361302006002006 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=209 [article] Body Mass Index in Male and Female Children with Infantile Autism [Texte imprimé et/ou numérique] / Svend Erik MOURIDSEN, Auteur ; Bente RICH, Auteur ; Torben ISAGER, Auteur . - p.197-205. Langues : Anglais (eng) in Autism > 6-2 (March 2002) . - p.197-205 Index. décimale : PER Périodiques Résumé : Morphometry, the measurement of forms, is an ancient practice. Recently, evidence has grown to support the notion that aberrant neurodevelopment may play a role in the pathophysiology of autism. Is the body, like the brain, affected by abnormal development in these patients? The aim of this study was to evaluate body mass index (BMI) of children with infantile autism, by comparing the BMI of 117 children with infantile autism with the corresponding BMI percentiles in an age- and sex-matched reference population. The BMI distribution of the male, but not female, children with infantile autism was significantly lower than that of the age-matched reference population. There was no evidence that BMI was associated with intelligence or socioeconomic status among children with infantile autism. En ligne : http://dx.doi.org/10.1177/1362361302006002006 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=209

Diseases of the gastrointestinal tract in individuals diagnosed as children with atypical autism: A Danish register study based on hospital diagnoses / Svend Erik MOURIDSEN in Autism, 17-1 (January 2013)  

Public ISBD [article]  inAutism > 17-1 (January 2013) . - p.55-63 Titre : Diseases of the gastrointestinal tract in individuals diagnosed as children with atypical autism: A Danish register study based on hospital diagnoses Type de document : Texte imprimé et/ou numérique Auteurs : Svend Erik MOURIDSEN, Auteur ; Torben ISAGER, Auteur ; Bente RICH, Auteur Année de publication : 2013 Article en page(s) : p.55-63 Langues : Anglais (eng) Mots-clés : atypical autism  comorbidity  gastrointestinal diseases Index. décimale : PER Périodiques Résumé : The purpose of this study is to compare the prevalence and types of diseases (International Classification of Mental and Behavioural Disorders, 10th Edition codes K20–K93) relating to the gastrointestinal tract in a clinical sample of 89 individuals diagnosed as children with atypical autism/pervasive developmental disorder not otherwise specified with 258 controls from the general population. All participants were screened through the nationwide Danish National Hospital Register. The average observation time was 32.9 years, and mean age at the end of the observation period was 48.5 years. Among the 89 cases with atypical autism, a total of 22 (24.7%) were registered with at least one diagnosis of any disease of the gastrointestinal tract, against 47 of 258 (18.2%) in the comparison group (p = 0.22; odds ratio = 1.5; 95% confidence interval = 0.8–2.6). Without reaching statistical significance, the rate of diseases of the gastrointestinal tract was particularly high (odds ratio = 1.2) in those with intelligence quotient 70. Overall, people with atypical autism had about the same frequency of gastric, intestinal and hepatic diseases as had controls. En ligne : http://dx.doi.org/10.1177/1362361312455110 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=192 [article] Diseases of the gastrointestinal tract in individuals diagnosed as children with atypical autism: A Danish register study based on hospital diagnoses [Texte imprimé et/ou numérique] / Svend Erik MOURIDSEN, Auteur ; Torben ISAGER, Auteur ; Bente RICH, Auteur . - 2013 . - p.55-63. Langues : Anglais (eng) in Autism > 17-1 (January 2013) . - p.55-63 Mots-clés : atypical autism  comorbidity  gastrointestinal diseases Index. décimale : PER Périodiques Résumé : The purpose of this study is to compare the prevalence and types of diseases (International Classification of Mental and Behavioural Disorders, 10th Edition codes K20–K93) relating to the gastrointestinal tract in a clinical sample of 89 individuals diagnosed as children with atypical autism/pervasive developmental disorder not otherwise specified with 258 controls from the general population. All participants were screened through the nationwide Danish National Hospital Register. The average observation time was 32.9 years, and mean age at the end of the observation period was 48.5 years. Among the 89 cases with atypical autism, a total of 22 (24.7%) were registered with at least one diagnosis of any disease of the gastrointestinal tract, against 47 of 258 (18.2%) in the comparison group (p = 0.22; odds ratio = 1.5; 95% confidence interval = 0.8–2.6). Without reaching statistical significance, the rate of diseases of the gastrointestinal tract was particularly high (odds ratio = 1.2) in those with intelligence quotient 70. Overall, people with atypical autism had about the same frequency of gastric, intestinal and hepatic diseases as had controls. En ligne : http://dx.doi.org/10.1177/1362361312455110 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=192

Epilepsy in Individuals with a History of Asperger’s Syndrome: A Danish Nationwide Register-Based Cohort Study / Svend Erik MOURIDSEN in Journal of Autism and Developmental Disorders, 43-6 (June 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-6 (June 2013) . - p.1308-1313 Titre : Epilepsy in Individuals with a History of Asperger’s Syndrome: A Danish Nationwide Register-Based Cohort Study Type de document : Texte imprimé et/ou numérique Auteurs : Svend Erik MOURIDSEN, Auteur ; Bente RICH, Auteur ; Torben ISAGER, Auteur Article en page(s) : p.1308-1313 Langues : Anglais (eng) Mots-clés : Asperger’s syndrome  Epilepsy  Prevalence  Comorbidity Index. décimale : PER Périodiques Résumé : We performed a nationwide, register-based retrospective follow-up study of epilepsy in all people who were born between January 1, 1980 and June 29, 2006 and registered in the Danish Psychiatric Central Register with Asperger’s syndrome on February 7, 2011. All 4,180 identified cases with AS (3,431 males and 749 females) were screened through the nationwide Danish National Hospital Register (DNHR) with respect to epilepsy. Mean age at follow-up was 18.1 years (range 4–31 years). Of the 4,180 individuals with AS, 164 (3.9 %) were registered with at least one epilepsy diagnosis in the DNHR, which is significantly increased (p 0.0001) relative to the same age group in the general population, where an estimate is about 2.0 %. En ligne : http://dx.doi.org/10.1007/s10803-012-1675-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=201 [article] Epilepsy in Individuals with a History of Asperger’s Syndrome: A Danish Nationwide Register-Based Cohort Study [Texte imprimé et/ou numérique] / Svend Erik MOURIDSEN, Auteur ; Bente RICH, Auteur ; Torben ISAGER, Auteur . - p.1308-1313. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-6 (June 2013) . - p.1308-1313 Mots-clés : Asperger’s syndrome  Epilepsy  Prevalence  Comorbidity Index. décimale : PER Périodiques Résumé : We performed a nationwide, register-based retrospective follow-up study of epilepsy in all people who were born between January 1, 1980 and June 29, 2006 and registered in the Danish Psychiatric Central Register with Asperger’s syndrome on February 7, 2011. All 4,180 identified cases with AS (3,431 males and 749 females) were screened through the nationwide Danish National Hospital Register (DNHR) with respect to epilepsy. Mean age at follow-up was 18.1 years (range 4–31 years). Of the 4,180 individuals with AS, 164 (3.9 %) were registered with at least one epilepsy diagnosis in the DNHR, which is significantly increased (p 0.0001) relative to the same age group in the general population, where an estimate is about 2.0 %. En ligne : http://dx.doi.org/10.1007/s10803-012-1675-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=201

Fractures in Individuals With and Without a History of Infantile Autism. A Danish Register Study Based on Hospital Discharge Diagnoses / Svend Erik MOURIDSEN in Journal of Autism and Developmental Disorders, 42-4 (April 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-4 (April 2012) . - p.619-624 Titre : Fractures in Individuals With and Without a History of Infantile Autism. A Danish Register Study Based on Hospital Discharge Diagnoses Type de document : Texte imprimé et/ou numérique Auteurs : Svend Erik MOURIDSEN, Auteur ; Bente RICH, Auteur ; Torben ISAGER, Auteur Année de publication : 2012 Article en page(s) : p.619-624 Langues : Anglais (eng) Mots-clés : Infantile autism  Fractures  Bone health  Epilepsy Index. décimale : PER Périodiques Résumé : We compared the prevalence and types of fractures in a clinical sample of 118 individuals diagnosed as children with infantile autism (IA) with 336 matched controls from the general population. All participants were screened through the nationwide Danish National Hospital Register. The average observation time was 30.3 years (range 27.3–30.4 years), and mean age at follow-up was 42.7 years (range 27.3–57.3 years). Of the 118 individuals with IA, 14 (11.9%) were registered with at least one fracture diagnosis against 83 (24.7%) in the comparison group ( p = 0.004; OR = 0.41; 95%CI 0.22–0.76), but the nature of their fractures seems somewhat different. Epilepsy was a risk factor, but only in the comparison group. Our results lend no support to the notion that fracture is a common comorbid condition in a population of people diagnosed with IA as children. En ligne : http://dx.doi.org/10.1007/s10803-011-1286-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=154 [article] Fractures in Individuals With and Without a History of Infantile Autism. A Danish Register Study Based on Hospital Discharge Diagnoses [Texte imprimé et/ou numérique] / Svend Erik MOURIDSEN, Auteur ; Bente RICH, Auteur ; Torben ISAGER, Auteur . - 2012 . - p.619-624. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-4 (April 2012) . - p.619-624 Mots-clés : Infantile autism  Fractures  Bone health  Epilepsy Index. décimale : PER Périodiques Résumé : We compared the prevalence and types of fractures in a clinical sample of 118 individuals diagnosed as children with infantile autism (IA) with 336 matched controls from the general population. All participants were screened through the nationwide Danish National Hospital Register. The average observation time was 30.3 years (range 27.3–30.4 years), and mean age at follow-up was 42.7 years (range 27.3–57.3 years). Of the 118 individuals with IA, 14 (11.9%) were registered with at least one fracture diagnosis against 83 (24.7%) in the comparison group ( p = 0.004; OR = 0.41; 95%CI 0.22–0.76), but the nature of their fractures seems somewhat different. Epilepsy was a risk factor, but only in the comparison group. Our results lend no support to the notion that fracture is a common comorbid condition in a population of people diagnosed with IA as children. En ligne : http://dx.doi.org/10.1007/s10803-011-1286-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=154

Mortality and causes of death in autism spectrum disorders: An update / Svend Erik MOURIDSEN in Autism, 12-4 (July 2008)  

Public ISBD [article]  inAutism > 12-4 (July 2008) . - p.403-414 Titre : Mortality and causes of death in autism spectrum disorders: An update Type de document : Texte imprimé et/ou numérique Auteurs : Svend Erik MOURIDSEN, Auteur ; Henrik BRONNUM-HANSEN, Auteur ; Bente RICH, Auteur ; Torben ISAGER, Auteur Année de publication : 2008 Article en page(s) : p.403-414 Langues : Anglais (eng) Mots-clés : autism-spectrum-disorders cause-of-death mortality standardized-mortality-ratio Index. décimale : PER Périodiques Résumé : This study compared mortality among Danish citizens with autism spectrum disorders (ASDs) with that of the general population. A clinical cohort of 341 Danish individuals with variants of ASD, previously followed over the period 1960—93, now on average 43 years of age, were updated with respect to mortality and causes of death. Standardized mortality ratios (SMRs) were calculated for various times after diagnosis. In all, 26 persons with ASD had died, whereas the expected number of deaths was 13.5. Thus the mortality risk among those with ASD was nearly twice that of the general population. The SMR was particularly high in females. The excess mortality risk has remained unchanged since our first study in 1993. Eight of the 26 deaths were associated with epilepsy and four died from epilepsy. Future staff education should focus on better managing of the complex relationships between ASD and physical illness to prevent avoidable deaths. En ligne : http://dx.doi.org/10.1177/1362361308091653 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=535 [article] Mortality and causes of death in autism spectrum disorders: An update [Texte imprimé et/ou numérique] / Svend Erik MOURIDSEN, Auteur ; Henrik BRONNUM-HANSEN, Auteur ; Bente RICH, Auteur ; Torben ISAGER, Auteur . - 2008 . - p.403-414. Langues : Anglais (eng) in Autism > 12-4 (July 2008) . - p.403-414 Mots-clés : autism-spectrum-disorders cause-of-death mortality standardized-mortality-ratio Index. décimale : PER Périodiques Résumé : This study compared mortality among Danish citizens with autism spectrum disorders (ASDs) with that of the general population. A clinical cohort of 341 Danish individuals with variants of ASD, previously followed over the period 1960—93, now on average 43 years of age, were updated with respect to mortality and causes of death. Standardized mortality ratios (SMRs) were calculated for various times after diagnosis. In all, 26 persons with ASD had died, whereas the expected number of deaths was 13.5. Thus the mortality risk among those with ASD was nearly twice that of the general population. The SMR was particularly high in females. The excess mortality risk has remained unchanged since our first study in 1993. Eight of the 26 deaths were associated with epilepsy and four died from epilepsy. Future staff education should focus on better managing of the complex relationships between ASD and physical illness to prevent avoidable deaths. En ligne : http://dx.doi.org/10.1177/1362361308091653 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=535

Mortality and Causes of Death in Pervasive Developmental Disorders / Torben ISAGER in Autism, 3-1 (March 1999)  

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Risk of cancer in adult people diagnosed with infantile autism in childhood: A longitudinal case control study based on hospital discharge diagnoses / Svend Erik MOURIDSEN in Research in Autism Spectrum Disorders, 23 (March 2016)  

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