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Fractures in Individuals With and Without a History of Infantile Autism. A Danish Register Study Based on Hospital Discharge Diagnoses / Svend Erik MOURIDSEN in Journal of Autism and Developmental Disorders, 42-4 (April 2012)
[article]
Titre : Fractures in Individuals With and Without a History of Infantile Autism. A Danish Register Study Based on Hospital Discharge Diagnoses Type de document : Texte imprimé et/ou numérique Auteurs : Svend Erik MOURIDSEN, Auteur ; Bente RICH, Auteur ; Torben ISAGER, Auteur Année de publication : 2012 Article en page(s) : p.619-624 Langues : Anglais (eng) Mots-clés : Infantile autism Fractures Bone health Epilepsy Index. décimale : PER Périodiques Résumé : We compared the prevalence and types of fractures in a clinical sample of 118 individuals diagnosed as children with infantile autism (IA) with 336 matched controls from the general population. All participants were screened through the nationwide Danish National Hospital Register. The average observation time was 30.3 years (range 27.3–30.4 years), and mean age at follow-up was 42.7 years (range 27.3–57.3 years). Of the 118 individuals with IA, 14 (11.9%) were registered with at least one fracture diagnosis against 83 (24.7%) in the comparison group ( p = 0.004; OR = 0.41; 95%CI 0.22–0.76), but the nature of their fractures seems somewhat different. Epilepsy was a risk factor, but only in the comparison group. Our results lend no support to the notion that fracture is a common comorbid condition in a population of people diagnosed with IA as children. En ligne : http://dx.doi.org/10.1007/s10803-011-1286-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=154
in Journal of Autism and Developmental Disorders > 42-4 (April 2012) . - p.619-624[article] Fractures in Individuals With and Without a History of Infantile Autism. A Danish Register Study Based on Hospital Discharge Diagnoses [Texte imprimé et/ou numérique] / Svend Erik MOURIDSEN, Auteur ; Bente RICH, Auteur ; Torben ISAGER, Auteur . - 2012 . - p.619-624.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-4 (April 2012) . - p.619-624
Mots-clés : Infantile autism Fractures Bone health Epilepsy Index. décimale : PER Périodiques Résumé : We compared the prevalence and types of fractures in a clinical sample of 118 individuals diagnosed as children with infantile autism (IA) with 336 matched controls from the general population. All participants were screened through the nationwide Danish National Hospital Register. The average observation time was 30.3 years (range 27.3–30.4 years), and mean age at follow-up was 42.7 years (range 27.3–57.3 years). Of the 118 individuals with IA, 14 (11.9%) were registered with at least one fracture diagnosis against 83 (24.7%) in the comparison group ( p = 0.004; OR = 0.41; 95%CI 0.22–0.76), but the nature of their fractures seems somewhat different. Epilepsy was a risk factor, but only in the comparison group. Our results lend no support to the notion that fracture is a common comorbid condition in a population of people diagnosed with IA as children. En ligne : http://dx.doi.org/10.1007/s10803-011-1286-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=154 Risk of cancer in adult people diagnosed with infantile autism in childhood: A longitudinal case control study based on hospital discharge diagnoses / Svend Erik MOURIDSEN in Research in Autism Spectrum Disorders, 23 (March 2016)
[article]
Titre : Risk of cancer in adult people diagnosed with infantile autism in childhood: A longitudinal case control study based on hospital discharge diagnoses Type de document : Texte imprimé et/ou numérique Auteurs : Svend Erik MOURIDSEN, Auteur ; Bente RICH, Auteur ; Torben ISAGER, Auteur Article en page(s) : p.203-209 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders Infantile autism Cancer Gender Intelligence Index. décimale : PER Périodiques Résumé : Abstract Research dealing with adults with autism spectrum disorders (ASD) noticeably lags behind studies of children and young individuals with ASD. The objective of this study is to compare the incidence and types of cancer in a clinical sample of 118 adult people diagnosed with infantile autism (IA) in childhood with 336 sex and age matched controls from the general population. All participants were screened through the nationwide Danish National Hospital Register. The average study interval of both groups was 37.2 years, and mean age at follow-up was 49.6 years. Of the 118 people with IA, 8 (6.8%) were registered with at least one cancer diagnosis against 17 (5.1%) in the comparison group (p = 0.49; OR = 1.4; 95% CI 0.6–3.3). Significant group differences were also lacking with respect to specific cancer types. En ligne : http://dx.doi.org/10.1016/j.rasd.2015.12.010 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=283
in Research in Autism Spectrum Disorders > 23 (March 2016) . - p.203-209[article] Risk of cancer in adult people diagnosed with infantile autism in childhood: A longitudinal case control study based on hospital discharge diagnoses [Texte imprimé et/ou numérique] / Svend Erik MOURIDSEN, Auteur ; Bente RICH, Auteur ; Torben ISAGER, Auteur . - p.203-209.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 23 (March 2016) . - p.203-209
Mots-clés : Autism spectrum disorders Infantile autism Cancer Gender Intelligence Index. décimale : PER Périodiques Résumé : Abstract Research dealing with adults with autism spectrum disorders (ASD) noticeably lags behind studies of children and young individuals with ASD. The objective of this study is to compare the incidence and types of cancer in a clinical sample of 118 adult people diagnosed with infantile autism (IA) in childhood with 336 sex and age matched controls from the general population. All participants were screened through the nationwide Danish National Hospital Register. The average study interval of both groups was 37.2 years, and mean age at follow-up was 49.6 years. Of the 118 people with IA, 8 (6.8%) were registered with at least one cancer diagnosis against 17 (5.1%) in the comparison group (p = 0.49; OR = 1.4; 95% CI 0.6–3.3). Significant group differences were also lacking with respect to specific cancer types. En ligne : http://dx.doi.org/10.1016/j.rasd.2015.12.010 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=283 Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study / Zeyan LIEW in Autism Research, 9-9 (September 2016)
[article]
Titre : Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study Type de document : Texte imprimé et/ou numérique Auteurs : Zeyan LIEW, Auteur ; Beate RITZ, Auteur ; Jasveer VIRK, Auteur ; Jørn OLSEN, Auteur Article en page(s) : p.951-958 Langues : Anglais (eng) Mots-clés : acetaminophen autism spectrum disorders infantile autism childhood behavior prenatal exposure pregnancy cohort Index. décimale : PER Périodiques Résumé : Acetaminophen (paracetamol) is the most commonly used pain and fever medication during pregnancy. Previously, a positive ecological correlation between acetaminophen use and autism spectrum disorders (ASD) has been reported but evidence from larger studies based on prospective data is lacking. We followed 64,322 children and mothers enrolled in the Danish National Birth Cohort (DNBC; 1996–2002) for average 12.7 years to investigate whether acetaminophen use in pregnancy is associated with increased risk of ASD in the offspring. Information on acetaminophen use was collected prospectively from three computer-assisted telephone interviews. We used records from the Danish hospital and psychiatric registries to identify diagnoses of ASD. At the end of follow up, 1,027 (1.6%) children were diagnosed with ASD, 345 (0.5%) with infantile autism. We found that 31% of ASD (26% of infantile autism) have also been diagnosed with hyperkinetic disorders. More than 50% women reported ever using acetaminophen in pregnancy. We used Cox proportional hazards model to estimate hazard ratio (HR) and 95% confident interval (CI). Prenatal use of acetaminophen was associated with an increased risk of ASD accompanied by hyperkinetic symptoms (HR?=?1.51 95% CI 1.19–1.92), but not with other ASD cases (HR?=?1.06 95% CI 0.92–1.24). Longer duration of use (i.e., use for >20 weeks in gestation) increased the risk of ASD or infantile autism with hyperkinetic symptoms almost twofold. Maternal use of acetaminophen in pregnancy was associated with ASD with hyperkinetic symptoms only, suggesting acetaminophen exposure early in fetal life may specifically impact this hyperactive behavioral phenotype. Autism Res 2016, 9: 951–958. En ligne : http://dx.doi.org/10.1002/aur.1591 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294
in Autism Research > 9-9 (September 2016) . - p.951-958[article] Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study [Texte imprimé et/ou numérique] / Zeyan LIEW, Auteur ; Beate RITZ, Auteur ; Jasveer VIRK, Auteur ; Jørn OLSEN, Auteur . - p.951-958.
Langues : Anglais (eng)
in Autism Research > 9-9 (September 2016) . - p.951-958
Mots-clés : acetaminophen autism spectrum disorders infantile autism childhood behavior prenatal exposure pregnancy cohort Index. décimale : PER Périodiques Résumé : Acetaminophen (paracetamol) is the most commonly used pain and fever medication during pregnancy. Previously, a positive ecological correlation between acetaminophen use and autism spectrum disorders (ASD) has been reported but evidence from larger studies based on prospective data is lacking. We followed 64,322 children and mothers enrolled in the Danish National Birth Cohort (DNBC; 1996–2002) for average 12.7 years to investigate whether acetaminophen use in pregnancy is associated with increased risk of ASD in the offspring. Information on acetaminophen use was collected prospectively from three computer-assisted telephone interviews. We used records from the Danish hospital and psychiatric registries to identify diagnoses of ASD. At the end of follow up, 1,027 (1.6%) children were diagnosed with ASD, 345 (0.5%) with infantile autism. We found that 31% of ASD (26% of infantile autism) have also been diagnosed with hyperkinetic disorders. More than 50% women reported ever using acetaminophen in pregnancy. We used Cox proportional hazards model to estimate hazard ratio (HR) and 95% confident interval (CI). Prenatal use of acetaminophen was associated with an increased risk of ASD accompanied by hyperkinetic symptoms (HR?=?1.51 95% CI 1.19–1.92), but not with other ASD cases (HR?=?1.06 95% CI 0.92–1.24). Longer duration of use (i.e., use for >20 weeks in gestation) increased the risk of ASD or infantile autism with hyperkinetic symptoms almost twofold. Maternal use of acetaminophen in pregnancy was associated with ASD with hyperkinetic symptoms only, suggesting acetaminophen exposure early in fetal life may specifically impact this hyperactive behavioral phenotype. Autism Res 2016, 9: 951–958. En ligne : http://dx.doi.org/10.1002/aur.1591 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294 Does Autism Diagnosis Age or Symptom Severity Differ Among Children According to Whether Assisted Reproductive Technology was Used to Achieve Pregnancy? / Laura A. SCHIEVE in Journal of Autism and Developmental Disorders, 45-9 (September 2015)
[article]
Titre : Does Autism Diagnosis Age or Symptom Severity Differ Among Children According to Whether Assisted Reproductive Technology was Used to Achieve Pregnancy? Type de document : Texte imprimé et/ou numérique Auteurs : Laura A. SCHIEVE, Auteur ; Christine FOUNTAIN, Auteur ; Sheree L. BOULET, Auteur ; Marshalyn YEARGIN-ALLSOPP, Auteur ; Dmitry M. KISSIN, Auteur ; Denise J. JAMIESON, Auteur ; Catherine RICE, Auteur ; Peter BEARMAN, Auteur Article en page(s) : p.2991-3003 Langues : Anglais (eng) Mots-clés : Infantile autism Symptom severity Diagnosis age Assisted reproductive technology Index. décimale : PER Périodiques Résumé : Previous studies report associations between conception with assisted reproductive technology (ART) and autism. Whether these associations reflect an ascertainment or biologic effect is undetermined. We assessed diagnosis age and initial autism symptom severity among >30,000 children with autism from a linkage study of California Department of Developmental Services records, birth records, and the National ART Surveillance System. Median diagnosis age and symptom severity levels were significantly lower for ART-conceived than non-ART-conceived children. After adjustment for differences in the socio-demographic profiles of the two groups, the diagnosis age differentials were greatly attenuated and there were no differences in autism symptomatology. Thus, ascertainment issues related to SES, not ART per se, are likely the driving influence of the differences we initially observed. En ligne : http://dx.doi.org/10.1007/s10803-015-2462-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=267
in Journal of Autism and Developmental Disorders > 45-9 (September 2015) . - p.2991-3003[article] Does Autism Diagnosis Age or Symptom Severity Differ Among Children According to Whether Assisted Reproductive Technology was Used to Achieve Pregnancy? [Texte imprimé et/ou numérique] / Laura A. SCHIEVE, Auteur ; Christine FOUNTAIN, Auteur ; Sheree L. BOULET, Auteur ; Marshalyn YEARGIN-ALLSOPP, Auteur ; Dmitry M. KISSIN, Auteur ; Denise J. JAMIESON, Auteur ; Catherine RICE, Auteur ; Peter BEARMAN, Auteur . - p.2991-3003.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 45-9 (September 2015) . - p.2991-3003
Mots-clés : Infantile autism Symptom severity Diagnosis age Assisted reproductive technology Index. décimale : PER Périodiques Résumé : Previous studies report associations between conception with assisted reproductive technology (ART) and autism. Whether these associations reflect an ascertainment or biologic effect is undetermined. We assessed diagnosis age and initial autism symptom severity among >30,000 children with autism from a linkage study of California Department of Developmental Services records, birth records, and the National ART Surveillance System. Median diagnosis age and symptom severity levels were significantly lower for ART-conceived than non-ART-conceived children. After adjustment for differences in the socio-demographic profiles of the two groups, the diagnosis age differentials were greatly attenuated and there were no differences in autism symptomatology. Thus, ascertainment issues related to SES, not ART per se, are likely the driving influence of the differences we initially observed. En ligne : http://dx.doi.org/10.1007/s10803-015-2462-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=267 Leo Kanner’s Mention of 1938 in His Report on Autism Refers to His First Patient / Dan OLMSTED in Journal of Autism and Developmental Disorders, 46-1 (January 2016)
[article]
Titre : Leo Kanner’s Mention of 1938 in His Report on Autism Refers to His First Patient Type de document : Texte imprimé et/ou numérique Auteurs : Dan OLMSTED, Auteur ; Mark BLAXILL, Auteur Année de publication : 2016 Article en page(s) : p.340-341 Langues : Anglais (eng) Mots-clés : History Leo Kanner Infantile autism Louise Despert Childhood schizophrenia Index. décimale : PER Périodiques Résumé : Leo Kanner begins his landmark 1943 case series on autistic children by stating the condition was first brought to his attention in 1938. Recent letters to JADD have described this reference as “mysterious” and speculated it refers to papers published that year by Despert or Asperger. In fact, as Kanner goes on to state, 1938 is when he examined the first child in his case series. An exchange of letters with Despert and later writing by Kanner also point to the originality of his observations. En ligne : http://dx.doi.org/10.1007/s10803-015-2541-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278
in Journal of Autism and Developmental Disorders > 46-1 (January 2016) . - p.340-341[article] Leo Kanner’s Mention of 1938 in His Report on Autism Refers to His First Patient [Texte imprimé et/ou numérique] / Dan OLMSTED, Auteur ; Mark BLAXILL, Auteur . - 2016 . - p.340-341.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 46-1 (January 2016) . - p.340-341
Mots-clés : History Leo Kanner Infantile autism Louise Despert Childhood schizophrenia Index. décimale : PER Périodiques Résumé : Leo Kanner begins his landmark 1943 case series on autistic children by stating the condition was first brought to his attention in 1938. Recent letters to JADD have described this reference as “mysterious” and speculated it refers to papers published that year by Despert or Asperger. In fact, as Kanner goes on to state, 1938 is when he examined the first child in his case series. An exchange of letters with Despert and later writing by Kanner also point to the originality of his observations. En ligne : http://dx.doi.org/10.1007/s10803-015-2541-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278