Associations of unintended pregnancy with autism spectrum disorders and the modification of folic acid supplements / Xing-Lian LIU ; Li-Zi LIN ; Xin WANG ; Ming-Hui LI ; Mei-Xia DAI ; Mu-Qing CAO ; Xiu-Hong LI ; Jing JIN ; Hai-Qing XU ; Li CAI in Autism Research, 17-1 (January 2024)  

Public ISBD [article]  inAutism Research > 17-1 (January 2024) . - p.172-181 Titre : Associations of unintended pregnancy with autism spectrum disorders and the modification of folic acid supplements Type de document : Texte imprimé et/ou numérique Auteurs : Xing-Lian LIU, Auteur ; Li-Zi LIN, Auteur ; Xin WANG, Auteur ; Ming-Hui LI, Auteur ; Mei-Xia DAI, Auteur ; Mu-Qing CAO, Auteur ; Xiu-Hong LI, Auteur ; Jing JIN, Auteur ; Hai-Qing XU, Auteur ; Li CAI, Auteur Article en page(s) : p.172-181 Index. décimale : PER Périodiques Résumé : Abstract There is limited evidence on the associations of unintended pregnancy with autism spectrum disorders (ASD). This study aimed to examine this relationship and the modification of pre-conceptional and prenatal folic acid supplements. Six thousand and five toddlers aged 16 to 30?months from seven cities of six provinces in China were eligible for participation. Information on unintended pregnancy and folic acid supplements was obtained via questionnaires from caregivers of toddlers. The diagnosis of ASD was based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) and the Chinese version of the Childhood Autism Rating Scale (CARS). Of the 6005 toddlers in the study (3337 boys and 2668 girls), 71 (1.18%) received the diagnosis of ASD. Generalized linear models with a logit link function showed unintended pregnancy was positively associated with ASD (odds ratios [OR]?=?1.69, 95% confidence interval [CI], 1.05?2.79). Stratified estimates indicated that the association remained stable among toddlers of mothers without pre-conceptional and prenatal folic acid supplements (OR?=?2.75, 95% CI, 1.04?7.27; n?=?1243, 20.70%). Unintended pregnancy was associated with higher odds of ASD in 16?30?months of toddlers, and the association was consistent among toddlers of mothers without prenatal folic acid supplements. Our findings emphasize the need to raise awareness of the risk of unintended pregnancy and the benefits of folic acid supplements among Chinese women. En ligne : https://doi.org/10.1002/aur.3070 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=519 [article] Associations of unintended pregnancy with autism spectrum disorders and the modification of folic acid supplements [Texte imprimé et/ou numérique] / Xing-Lian LIU, Auteur ; Li-Zi LIN, Auteur ; Xin WANG, Auteur ; Ming-Hui LI, Auteur ; Mei-Xia DAI, Auteur ; Mu-Qing CAO, Auteur ; Xiu-Hong LI, Auteur ; Jing JIN, Auteur ; Hai-Qing XU, Auteur ; Li CAI, Auteur . - p.172-181. in Autism Research > 17-1 (January 2024) . - p.172-181 Index. décimale : PER Périodiques Résumé : Abstract There is limited evidence on the associations of unintended pregnancy with autism spectrum disorders (ASD). This study aimed to examine this relationship and the modification of pre-conceptional and prenatal folic acid supplements. Six thousand and five toddlers aged 16 to 30?months from seven cities of six provinces in China were eligible for participation. Information on unintended pregnancy and folic acid supplements was obtained via questionnaires from caregivers of toddlers. The diagnosis of ASD was based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) and the Chinese version of the Childhood Autism Rating Scale (CARS). Of the 6005 toddlers in the study (3337 boys and 2668 girls), 71 (1.18%) received the diagnosis of ASD. Generalized linear models with a logit link function showed unintended pregnancy was positively associated with ASD (odds ratios [OR]?=?1.69, 95% confidence interval [CI], 1.05?2.79). Stratified estimates indicated that the association remained stable among toddlers of mothers without pre-conceptional and prenatal folic acid supplements (OR?=?2.75, 95% CI, 1.04?7.27; n?=?1243, 20.70%). Unintended pregnancy was associated with higher odds of ASD in 16?30?months of toddlers, and the association was consistent among toddlers of mothers without prenatal folic acid supplements. Our findings emphasize the need to raise awareness of the risk of unintended pregnancy and the benefits of folic acid supplements among Chinese women. En ligne : https://doi.org/10.1002/aur.3070 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=519

Psychometric properties of the Chinese version of the children's empathy quotient and systemizing quotient: 4-12years / Xin WANG in Autism Research, 15-9 (September 2022)  

Public ISBD [article]  inAutism Research > 15-9 (September 2022) . - p.1675-1685 Titre : Psychometric properties of the Chinese version of the children's empathy quotient and systemizing quotient: 4-12years Type de document : Texte imprimé et/ou numérique Auteurs : Xin WANG, Auteur ; Mei-Xia DAI, Auteur ; Aja MURRAY, Auteur ; Si-Yu LIU, Auteur ; Jia-Jie CHEN, Auteur ; Li-Zi LIN, Auteur ; Jin JING, Auteur ; Bonnie AUYEUNG, Auteur Article en page(s) : p.1675-1685 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/psychology  Child  Empathy  Female  Humans  Intelligence  Male  Psychometrics  Reproducibility of Results  autism spectrum disorder  children  empathy quotient  gender differences  systemizing quotient Index. décimale : PER Périodiques Résumé : We aimed to validate the Children's Empathy Quotient (EQ-C) and Systemizing Quotient (SQ-C) in Mainland China, which can reflect the profiles of empathizing and systemizing, and describing specific characteristics of autism spectrum disorder (ASD) and gender-typical behaviors in general population. A total of 800 typically developing (TD) children, aged 4-12years was recruited initially with whose parents/guardians complete the measurements, and 782 TD children who met inclusion criteria were finally included. A 23-item three-factor EQ-C and a 22-item four-factor SQ-C was developed with good internal consistency (Omega total values of 0.87 and 0.86) and test-retest reliability (Pearson correlation coefficients of 0.82 and 0.69). In TD children, girls scored significantly higher on EQ-C (31.4Â+7.8 vs. 28.2Â+7.7) but there were no gender differences in SQ-C scores. TD children showed different cognitive styles (empathizing-dominant for girls with 42.6% identified as Type E; systemizing-dominant for boys with 40.7% identified as Type S). A further sample of 222 children with ASD indicated that they scored lower on EQ/SQ-C compared to TD children (13.2Â+5.1 vs. 29.7Â+7.9, 12.4Â+5.8 vs. 23.5Â+8.3) and were generally systemizing-dominant (Type S: 50.8% for boys and 64.0% for girls). Autistic children scored higher on the SQ-C in those without intellectual disability and with higher paternal education level and family income (14.2Â+6.1 vs. 10.9Â+5.0, 13.3Â+6.2 vs. 11.5Â+5.1, 13.7Â+5.6 vs. 11.9Â+5.8), while there were no differences in the EQ-C. This study indicated good reliability and validity of the Chinese version of EQ/SQ-C, which can be used in Chinese children with and without ASD. LAY SUMMARY: We developed the Chinese version of the Children's Empathy Quotient (EQ-C) and Systemizing Quotient (SQ-C) in 782 typically developing (TD) children aged 4-12years in Mainland China, yielding a 23-item, 3-factor EQ-C and a 22-item, 4-factor SQ-C with good psychometric properties. In TD children, we found gender difference only in scores of EQ-C. Further analyses of 222 autistic children indicated that differences were found in scores of SQ-C when considering their gender, intelligence and socio-economic status. En ligne : http://dx.doi.org/10.1002/aur.2743 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=483 [article] Psychometric properties of the Chinese version of the children's empathy quotient and systemizing quotient: 4-12years [Texte imprimé et/ou numérique] / Xin WANG, Auteur ; Mei-Xia DAI, Auteur ; Aja MURRAY, Auteur ; Si-Yu LIU, Auteur ; Jia-Jie CHEN, Auteur ; Li-Zi LIN, Auteur ; Jin JING, Auteur ; Bonnie AUYEUNG, Auteur . - p.1675-1685. Langues : Anglais (eng) in Autism Research > 15-9 (September 2022) . - p.1675-1685 Mots-clés : Autism Spectrum Disorder/psychology  Child  Empathy  Female  Humans  Intelligence  Male  Psychometrics  Reproducibility of Results  autism spectrum disorder  children  empathy quotient  gender differences  systemizing quotient Index. décimale : PER Périodiques Résumé : We aimed to validate the Children's Empathy Quotient (EQ-C) and Systemizing Quotient (SQ-C) in Mainland China, which can reflect the profiles of empathizing and systemizing, and describing specific characteristics of autism spectrum disorder (ASD) and gender-typical behaviors in general population. A total of 800 typically developing (TD) children, aged 4-12years was recruited initially with whose parents/guardians complete the measurements, and 782 TD children who met inclusion criteria were finally included. A 23-item three-factor EQ-C and a 22-item four-factor SQ-C was developed with good internal consistency (Omega total values of 0.87 and 0.86) and test-retest reliability (Pearson correlation coefficients of 0.82 and 0.69). In TD children, girls scored significantly higher on EQ-C (31.4Â+7.8 vs. 28.2Â+7.7) but there were no gender differences in SQ-C scores. TD children showed different cognitive styles (empathizing-dominant for girls with 42.6% identified as Type E; systemizing-dominant for boys with 40.7% identified as Type S). A further sample of 222 children with ASD indicated that they scored lower on EQ/SQ-C compared to TD children (13.2Â+5.1 vs. 29.7Â+7.9, 12.4Â+5.8 vs. 23.5Â+8.3) and were generally systemizing-dominant (Type S: 50.8% for boys and 64.0% for girls). Autistic children scored higher on the SQ-C in those without intellectual disability and with higher paternal education level and family income (14.2Â+6.1 vs. 10.9Â+5.0, 13.3Â+6.2 vs. 11.5Â+5.1, 13.7Â+5.6 vs. 11.9Â+5.8), while there were no differences in the EQ-C. This study indicated good reliability and validity of the Chinese version of EQ/SQ-C, which can be used in Chinese children with and without ASD. LAY SUMMARY: We developed the Chinese version of the Children's Empathy Quotient (EQ-C) and Systemizing Quotient (SQ-C) in 782 typically developing (TD) children aged 4-12years in Mainland China, yielding a 23-item, 3-factor EQ-C and a 22-item, 4-factor SQ-C with good psychometric properties. In TD children, we found gender difference only in scores of EQ-C. Further analyses of 222 autistic children indicated that differences were found in scores of SQ-C when considering their gender, intelligence and socio-economic status. En ligne : http://dx.doi.org/10.1002/aur.2743 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=483

---

1 (1 - 2 / 2)