65 recherche sur le mot-clé 'Reproducibility of Results'

Controlling litter effects to enhance rigor and reproducibility with rodent models of neurodevelopmental disorders / Jessica A. JIMÉNEZ in Journal of Neurodevelopmental Disorders, 13 (2021)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 13 (2021) Titre : Controlling litter effects to enhance rigor and reproducibility with rodent models of neurodevelopmental disorders Type de document : texte imprimé Auteurs : Jessica A. JIMÉNEZ, Auteur ; Mark J. ZYLKA, Auteur Langues : Anglais (eng) Mots-clés : Animals  Female  Haploinsufficiency  Mice  Neurodevelopmental Disorders/chemically induced/genetics  Phenotype  Pregnancy  Reproducibility of Results  Animal models  Litter effect  Neurodevelopmental disorders  Rigor and reproducibility Index. décimale : PER Périodiques Résumé : Research with rodents is crucial for expanding our understanding of genetic and environmental risk factors for neurodevelopmental disorders (NDD). However, there is growing concern about the number of animal studies that are difficult to replicate, potentially undermining the validity of results. These concerns have prompted funding agencies and academic journals to implement more rigorous standards in an effort to increase reproducibility in research. However, these standards fail to address a major source of variability in rodent research brought on by the "litter effect," the fact that rodents from the same litter are phenotypically more similar to one other than rodents from different litters of the same strain. We show that the litter effect accounts for 30-60% of the variability associated with commonly studied phenotypes, including brain, placenta, and body weight. Moreover, we show how failure to control for litter-to-litter variation can mask a phenotype in Chd8(V986*/+) mice that model haploinsufficiency of CHD8, a high-confidence autism gene. Thus, if not properly controlled, the litter effect has the potential to negatively influence rigor and reproducibility of NDD research. While efforts have been made to educate scientists on the importance of controlling for litter effects in previous publications, our analysis of the recent literature (2015-2020) shows that the vast majority of NDD studies focused on genetic risks, including mutant mouse studies, and environmental risks, such as air pollution and valproic acid exposure, do not correct for litter effects or report information on the number of litters used. We outline best practices to help scientists minimize the impact of litter-to-litter variability and to enhance rigor and reproducibility in future NDD studies using rodent models. En ligne : https://dx.doi.org/10.1186/s11689-020-09353-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=573 [article] Controlling litter effects to enhance rigor and reproducibility with rodent models of neurodevelopmental disorders [texte imprimé] / Jessica A. JIMÉNEZ, Auteur ; Mark J. ZYLKA, Auteur. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 13 (2021) Mots-clés : Animals  Female  Haploinsufficiency  Mice  Neurodevelopmental Disorders/chemically induced/genetics  Phenotype  Pregnancy  Reproducibility of Results  Animal models  Litter effect  Neurodevelopmental disorders  Rigor and reproducibility Index. décimale : PER Périodiques Résumé : Research with rodents is crucial for expanding our understanding of genetic and environmental risk factors for neurodevelopmental disorders (NDD). However, there is growing concern about the number of animal studies that are difficult to replicate, potentially undermining the validity of results. These concerns have prompted funding agencies and academic journals to implement more rigorous standards in an effort to increase reproducibility in research. However, these standards fail to address a major source of variability in rodent research brought on by the "litter effect," the fact that rodents from the same litter are phenotypically more similar to one other than rodents from different litters of the same strain. We show that the litter effect accounts for 30-60% of the variability associated with commonly studied phenotypes, including brain, placenta, and body weight. Moreover, we show how failure to control for litter-to-litter variation can mask a phenotype in Chd8(V986*/+) mice that model haploinsufficiency of CHD8, a high-confidence autism gene. Thus, if not properly controlled, the litter effect has the potential to negatively influence rigor and reproducibility of NDD research. While efforts have been made to educate scientists on the importance of controlling for litter effects in previous publications, our analysis of the recent literature (2015-2020) shows that the vast majority of NDD studies focused on genetic risks, including mutant mouse studies, and environmental risks, such as air pollution and valproic acid exposure, do not correct for litter effects or report information on the number of litters used. We outline best practices to help scientists minimize the impact of litter-to-litter variability and to enhance rigor and reproducibility in future NDD studies using rodent models. En ligne : https://dx.doi.org/10.1186/s11689-020-09353-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=573

Distributional Properties and Criterion Validity of a Shortened Version of the Social Responsiveness Scale: Results from the ECHO Program and Implications for Social Communication Research / Kristen LYALL in Journal of Autism and Developmental Disorders, 51-7 (July 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-7 (July 2021) . - p.2241-2253 Titre : Distributional Properties and Criterion Validity of a Shortened Version of the Social Responsiveness Scale: Results from the ECHO Program and Implications for Social Communication Research Type de document : texte imprimé Auteurs : Kristen LYALL, Auteur ; Mina HOSSEINI, Auteur ; Christine LADD-ACOSTA, Auteur ; Xuejuan NING, Auteur ; Diane CATELLIER, Auteur ; John N. CONSTANTINO, Auteur ; Lisa A. CROEN, Auteur ; Aaron J. KAAT, Auteur ; Kelly N. BOTTERON, Auteur ; Nicole R. BUSH, Auteur ; Stephen R. DAGER, Auteur ; Cristiane S. DUARTE, Auteur ; M. Daniele FALLIN, Auteur ; Heather C. HAZLETT, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Robert M. JOSEPH, Auteur ; Margaret R. KARAGAS, Auteur ; Susan KORRICK, Auteur ; Rebecca LANDA, Auteur ; Daniel S. MESSINGER, Auteur ; Emily OKEN, Auteur ; Sally OZONOFF, Auteur ; Joseph PIVEN, Auteur ; Juhi PANDEY, Auteur ; Sheela SATHYANARAYA, Auteur ; Robert T. SCHULTZ, Auteur ; Tanya ST JOHN, Auteur ; Rebecca SCHMIDT, Auteur ; Heather E. VOLK, Auteur ; Craig J. NEWSCHAFFER, Auteur Article en page(s) : p.2241-2253 Langues : Anglais (eng) Mots-clés : Adolescent  Area Under Curve  Autism Spectrum Disorder/diagnosis  Child  Child, Preschool  Communication  Female  Humans  Male  Psychiatric Status Rating Scales/standards  Psychometrics  Reproducibility of Results  Social Behavior  Autism spectrum disorder  Quantitative traits  Social Responsiveness Scale  Social communication Index. décimale : PER Périodiques Résumé : Prior work proposed a shortened version of the Social Responsiveness Scale (SRS), a commonly used quantitative measure of social communication traits. We used data from 3031 participants (including 190 ASD cases) from the Environmental Influences on Child Health Outcomes (ECHO) Program to compare distributional properties and criterion validity of 16-item "short" to 65-item "full" SRS scores. Results demonstrated highly overlapping distributions of short and full scores. Both scores separated case from non-case individuals by approximately two standard deviations. ASD prediction was nearly identical for short and full scores (area under the curve values of 0.87, 0.86 respectively). Findings support comparability of shortened and full scores, suggesting opportunities to increase efficiency. Future work should confirm additional psychometric properties of short scores. En ligne : http://dx.doi.org/10.1007/s10803-020-04667-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452 [article] Distributional Properties and Criterion Validity of a Shortened Version of the Social Responsiveness Scale: Results from the ECHO Program and Implications for Social Communication Research [texte imprimé] / Kristen LYALL, Auteur ; Mina HOSSEINI, Auteur ; Christine LADD-ACOSTA, Auteur ; Xuejuan NING, Auteur ; Diane CATELLIER, Auteur ; John N. CONSTANTINO, Auteur ; Lisa A. CROEN, Auteur ; Aaron J. KAAT, Auteur ; Kelly N. BOTTERON, Auteur ; Nicole R. BUSH, Auteur ; Stephen R. DAGER, Auteur ; Cristiane S. DUARTE, Auteur ; M. Daniele FALLIN, Auteur ; Heather C. HAZLETT, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Robert M. JOSEPH, Auteur ; Margaret R. KARAGAS, Auteur ; Susan KORRICK, Auteur ; Rebecca LANDA, Auteur ; Daniel S. MESSINGER, Auteur ; Emily OKEN, Auteur ; Sally OZONOFF, Auteur ; Joseph PIVEN, Auteur ; Juhi PANDEY, Auteur ; Sheela SATHYANARAYA, Auteur ; Robert T. SCHULTZ, Auteur ; Tanya ST JOHN, Auteur ; Rebecca SCHMIDT, Auteur ; Heather E. VOLK, Auteur ; Craig J. NEWSCHAFFER, Auteur . - p.2241-2253. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-7 (July 2021) . - p.2241-2253 Mots-clés : Adolescent  Area Under Curve  Autism Spectrum Disorder/diagnosis  Child  Child, Preschool  Communication  Female  Humans  Male  Psychiatric Status Rating Scales/standards  Psychometrics  Reproducibility of Results  Social Behavior  Autism spectrum disorder  Quantitative traits  Social Responsiveness Scale  Social communication Index. décimale : PER Périodiques Résumé : Prior work proposed a shortened version of the Social Responsiveness Scale (SRS), a commonly used quantitative measure of social communication traits. We used data from 3031 participants (including 190 ASD cases) from the Environmental Influences on Child Health Outcomes (ECHO) Program to compare distributional properties and criterion validity of 16-item "short" to 65-item "full" SRS scores. Results demonstrated highly overlapping distributions of short and full scores. Both scores separated case from non-case individuals by approximately two standard deviations. ASD prediction was nearly identical for short and full scores (area under the curve values of 0.87, 0.86 respectively). Findings support comparability of shortened and full scores, suggesting opportunities to increase efficiency. Future work should confirm additional psychometric properties of short scores. En ligne : http://dx.doi.org/10.1007/s10803-020-04667-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452

Properties of beta oscillations in Dup15q syndrome / Vidya SARAVANAPANDIAN in Journal of Neurodevelopmental Disorders, 12 (2020)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 12 (2020) Titre : Properties of beta oscillations in Dup15q syndrome Type de document : texte imprimé Auteurs : Vidya SARAVANAPANDIAN, Auteur ; Joel FROHLICH, Auteur ; Joerg F. HIPP, Auteur ; Carly HYDE, Auteur ; Aaron W. SCHEFFLER, Auteur ; Peyman GOLSHANI, Auteur ; Edwin H. COOK, Auteur ; Lawrence T. REITER, Auteur ; Damla SENTURK, Auteur ; Shafali S. JESTE, Auteur Langues : Anglais (eng) Mots-clés : Child  Child, Preschool  Electroencephalography  Epilepsy  Follow-Up Studies  Humans  Infant  Intellectual Disability  Reproducibility of Results  Autism  Biomarkers  Dup15q syndrome  Eeg  Gaba  Neurodevelopmental disorders  UBE3A  of F. Hoffmann-La Roche Ltd. (October 2016–July 2017). Joerg F. Hipp is an  employee of F. Hoffmann-La Roche Ltd. Carly Hyde: no competing interests Aaron W.  Scheffler: no competing interests Peyman Golshani: no competing interests Edwin  H. Cook: no competing interests Lawrence T. Reiter: no competing interests Damla  Senturk: no competing interests Shafali Jeste serves as a consultant for and has  received funding from F. Hoffmann-La Roche Ltd. and Yamo Pharmaceuticals Index. décimale : PER Périodiques Résumé : BACKGROUND: Duplications of 15q11.2-q13.1 (Dup15q syndrome) are highly penetrant for autism, intellectual disability, hypotonia, and epilepsy. The 15q region harbors genes critical for brain development, particularly UBE3A and a cluster of gamma-aminobutyric acid type A receptor (GABA(A)R) genes. We recently described an electrophysiological biomarker of the syndrome, characterized by excessive beta oscillations (12-30 Hz), resembling electroencephalogram (EEG) changes induced by allosteric modulation of GABA(A)Rs. In this follow-up study, we tested a larger cohort of children with Dup15q syndrome to comprehensively examine properties of this EEG biomarker that would inform its use in future clinical trials, specifically, its (1) relation to basic clinical features, such as age, duplication type, and epilepsy; (2) relation to behavioral characteristics, such as cognition and adaptive function; (3) stability over time; and (4) reproducibility of the signal in clinical EEG recordings. METHODS: We computed EEG power and beta peak frequency (BPF) in a cohort of children with Dup15q syndrome (N = 41, age range 9-189 months). To relate EEG parameters to clinical (study 1) and behavioral features (study 2), we examined age, duplication type, epilepsy, cognition, and daily living skills (DLS) as predictors of beta power and BPF. To evaluate stability over time (study 3), we derived the intraclass correlation coefficients (ICC) from beta power and BPF computed from children with multiple EEG recordings (N = 10, age range 18-161 months). To evaluate reproducibility in a clinical setting (study 4), we derived ICCs from beta power computed from children (N = 8, age range 19-96 months), who had undergone both research EEG and clinical EEG. RESULTS: The most promising relationships between EEG and clinical traits were found using BPF. BPF was predicted both by epilepsy status (R(2) = 0.11, p = 0.038) and the DLS component of the Vineland Adaptive Behavior Scale (R(2) = 0.17, p = 0.01). Beta power and peak frequency showed high stability across repeated visits (beta power ICC = 0.93, BPF ICC = 0.92). A reproducibility analysis revealed that beta power estimates are comparable between research and clinical EEG (ICC = 0.94). CONCLUSIONS: In this era of precision health, with pharmacological and neuromodulatory therapies being developed and tested for specific genetic etiologies of neurodevelopmental disorders, quantification and examination of mechanistic biomarkers can greatly improve clinical trials. To this end, the robust beta oscillations evident in Dup15q syndrome are clinically reproducible and stable over time. With future preclinical and computational studies that will help disentangle the underlying mechanism, it is possible that this biomarker could serve as a robust measure of drug target engagement or a proximal outcome measure in future disease modifying intervention trials. En ligne : https://dx.doi.org/10.1186/s11689-020-09326-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=573 [article] Properties of beta oscillations in Dup15q syndrome [texte imprimé] / Vidya SARAVANAPANDIAN, Auteur ; Joel FROHLICH, Auteur ; Joerg F. HIPP, Auteur ; Carly HYDE, Auteur ; Aaron W. SCHEFFLER, Auteur ; Peyman GOLSHANI, Auteur ; Edwin H. COOK, Auteur ; Lawrence T. REITER, Auteur ; Damla SENTURK, Auteur ; Shafali S. JESTE, Auteur. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 12 (2020) Mots-clés : Child  Child, Preschool  Electroencephalography  Epilepsy  Follow-Up Studies  Humans  Infant  Intellectual Disability  Reproducibility of Results  Autism  Biomarkers  Dup15q syndrome  Eeg  Gaba  Neurodevelopmental disorders  UBE3A  of F. Hoffmann-La Roche Ltd. (October 2016–July 2017). Joerg F. Hipp is an  employee of F. Hoffmann-La Roche Ltd. Carly Hyde: no competing interests Aaron W.  Scheffler: no competing interests Peyman Golshani: no competing interests Edwin  H. Cook: no competing interests Lawrence T. Reiter: no competing interests Damla  Senturk: no competing interests Shafali Jeste serves as a consultant for and has  received funding from F. Hoffmann-La Roche Ltd. and Yamo Pharmaceuticals Index. décimale : PER Périodiques Résumé : BACKGROUND: Duplications of 15q11.2-q13.1 (Dup15q syndrome) are highly penetrant for autism, intellectual disability, hypotonia, and epilepsy. The 15q region harbors genes critical for brain development, particularly UBE3A and a cluster of gamma-aminobutyric acid type A receptor (GABA(A)R) genes. We recently described an electrophysiological biomarker of the syndrome, characterized by excessive beta oscillations (12-30 Hz), resembling electroencephalogram (EEG) changes induced by allosteric modulation of GABA(A)Rs. In this follow-up study, we tested a larger cohort of children with Dup15q syndrome to comprehensively examine properties of this EEG biomarker that would inform its use in future clinical trials, specifically, its (1) relation to basic clinical features, such as age, duplication type, and epilepsy; (2) relation to behavioral characteristics, such as cognition and adaptive function; (3) stability over time; and (4) reproducibility of the signal in clinical EEG recordings. METHODS: We computed EEG power and beta peak frequency (BPF) in a cohort of children with Dup15q syndrome (N = 41, age range 9-189 months). To relate EEG parameters to clinical (study 1) and behavioral features (study 2), we examined age, duplication type, epilepsy, cognition, and daily living skills (DLS) as predictors of beta power and BPF. To evaluate stability over time (study 3), we derived the intraclass correlation coefficients (ICC) from beta power and BPF computed from children with multiple EEG recordings (N = 10, age range 18-161 months). To evaluate reproducibility in a clinical setting (study 4), we derived ICCs from beta power computed from children (N = 8, age range 19-96 months), who had undergone both research EEG and clinical EEG. RESULTS: The most promising relationships between EEG and clinical traits were found using BPF. BPF was predicted both by epilepsy status (R(2) = 0.11, p = 0.038) and the DLS component of the Vineland Adaptive Behavior Scale (R(2) = 0.17, p = 0.01). Beta power and peak frequency showed high stability across repeated visits (beta power ICC = 0.93, BPF ICC = 0.92). A reproducibility analysis revealed that beta power estimates are comparable between research and clinical EEG (ICC = 0.94). CONCLUSIONS: In this era of precision health, with pharmacological and neuromodulatory therapies being developed and tested for specific genetic etiologies of neurodevelopmental disorders, quantification and examination of mechanistic biomarkers can greatly improve clinical trials. To this end, the robust beta oscillations evident in Dup15q syndrome are clinically reproducible and stable over time. With future preclinical and computational studies that will help disentangle the underlying mechanism, it is possible that this biomarker could serve as a robust measure of drug target engagement or a proximal outcome measure in future disease modifying intervention trials. En ligne : https://dx.doi.org/10.1186/s11689-020-09326-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=573

Towards greater transparency in neurodevelopmental disorders research: use of a proposed workflow and propensity scores to facilitate selection of matched groups / Janet Y. BANG in Journal of Neurodevelopmental Disorders, 12 (2020)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 12 (2020) Titre : Towards greater transparency in neurodevelopmental disorders research: use of a proposed workflow and propensity scores to facilitate selection of matched groups Type de document : texte imprimé Auteurs : Janet Y. BANG, Auteur ; Megha SHARDA, Auteur ; Aparna S. NADIG, Auteur Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/psychology  Bias  Child  Data Interpretation, Statistical  Female  Humans  Male  Neurodevelopmental Disorders  Patient Selection  Propensity Score  Reproducibility of Results  Research Design  Workflow  Covariate  Group comparison  Matching  Propensity score  Reproducibility  Transparency Index. décimale : PER Périodiques Résumé : BACKGROUND: Matching is one commonly utilized method in quasi-experimental designs involving individuals with neurodevelopmental disorders (NDD). This method ensures two or more groups (e.g., individuals with an NDD versus neurotypical individuals) are balanced on pre-existing covariates (e.g., IQ), enabling researchers to interpret performance on outcome measures as being attributed to group membership. While much attention has been paid to the statistical criteria of how to assess whether groups are well-matched, relatively little attention has been given to a crucial prior step: the selection of the individuals that are included in matched groups. The selection of individuals is often an undocumented process, which can invite unintentional, arbitrary, and biased decision-making. Limited documentation can result in findings that have limited reproducibility and replicability and thereby have poor potential for generalization to the broader population. Especially given the heterogeneity of individuals with NDDs, interpretation of research findings depends on minimizing bias at all stages of data collection and analysis. RESULTS: In the spirit of open science, this tutorial demonstrates how a workflow can be used to provide a transparent, reproducible, and replicable process to select individuals for matched groups. Our workflow includes the following key steps: Assess data, Select covariates, Conduct matching, and Diagnose matching. Our sample dataset is from children with autism spectrum disorder (ASD; n = 25) and typically developing children (n = 43) but can be adapted to comparisons of any two groups in quasi-experimental designs. We work through this method to conduct and document matching using propensity scores implemented with the R package MatchIt. Data and code are publicly available, and a template for this workflow is provided in the Additional file 1 as well as on a public repository. CONCLUSIONS: It is important to provide clear documentation regarding the selection process to establish matched groups. This documentation ensures better transparency in participant selection and data analysis in NDD research. We hope the adoption of such a workflow will ultimately advance our ability to replicate findings and help improve the lives of individuals with NDDs. En ligne : https://dx.doi.org/10.1186/s11689-020-09321-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=573 [article] Towards greater transparency in neurodevelopmental disorders research: use of a proposed workflow and propensity scores to facilitate selection of matched groups [texte imprimé] / Janet Y. BANG, Auteur ; Megha SHARDA, Auteur ; Aparna S. NADIG, Auteur. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 12 (2020) Mots-clés : Autism Spectrum Disorder/psychology  Bias  Child  Data Interpretation, Statistical  Female  Humans  Male  Neurodevelopmental Disorders  Patient Selection  Propensity Score  Reproducibility of Results  Research Design  Workflow  Covariate  Group comparison  Matching  Propensity score  Reproducibility  Transparency Index. décimale : PER Périodiques Résumé : BACKGROUND: Matching is one commonly utilized method in quasi-experimental designs involving individuals with neurodevelopmental disorders (NDD). This method ensures two or more groups (e.g., individuals with an NDD versus neurotypical individuals) are balanced on pre-existing covariates (e.g., IQ), enabling researchers to interpret performance on outcome measures as being attributed to group membership. While much attention has been paid to the statistical criteria of how to assess whether groups are well-matched, relatively little attention has been given to a crucial prior step: the selection of the individuals that are included in matched groups. The selection of individuals is often an undocumented process, which can invite unintentional, arbitrary, and biased decision-making. Limited documentation can result in findings that have limited reproducibility and replicability and thereby have poor potential for generalization to the broader population. Especially given the heterogeneity of individuals with NDDs, interpretation of research findings depends on minimizing bias at all stages of data collection and analysis. RESULTS: In the spirit of open science, this tutorial demonstrates how a workflow can be used to provide a transparent, reproducible, and replicable process to select individuals for matched groups. Our workflow includes the following key steps: Assess data, Select covariates, Conduct matching, and Diagnose matching. Our sample dataset is from children with autism spectrum disorder (ASD; n = 25) and typically developing children (n = 43) but can be adapted to comparisons of any two groups in quasi-experimental designs. We work through this method to conduct and document matching using propensity scores implemented with the R package MatchIt. Data and code are publicly available, and a template for this workflow is provided in the Additional file 1 as well as on a public repository. CONCLUSIONS: It is important to provide clear documentation regarding the selection process to establish matched groups. This documentation ensures better transparency in participant selection and data analysis in NDD research. We hope the adoption of such a workflow will ultimately advance our ability to replicate findings and help improve the lives of individuals with NDDs. En ligne : https://dx.doi.org/10.1186/s11689-020-09321-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=573

Adaptation, Content Validity and Reliability of the Autism Classification System of Functioning for Social Communication: From Toddlerhood to Adolescent-Aged Children with Autism / Briano DI REZZE in Journal of Autism and Developmental Disorders, 52-12 (December 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-12 (December 2022) . - p.5150-5161 Titre : Adaptation, Content Validity and Reliability of the Autism Classification System of Functioning for Social Communication: From Toddlerhood to Adolescent-Aged Children with Autism Type de document : texte imprimé Auteurs : Briano DI REZZE, Auteur ; Stephen J. GENTLES, Auteur ; Mary Jo Cooley HIDECKER, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Peter L. ROSENBAUM, Auteur ; Eric DUKU, Auteur ; Stelios GEORGIADES, Auteur ; Caroline RONCADIN, Auteur ; Hanna FANG, Auteur ; Diana J. TAJIK-PARVINCHI, Auteur ; Helena VIVEIROS, Auteur Année de publication : 2022 Article en page(s) : p.5150-5161 Langues : Anglais (eng) Mots-clés : Child  Adolescent  Humans  Aged  Child, Preschool  Autism Spectrum Disorder  Autistic Disorder/diagnosis  Reproducibility of Results  Communication  Parents  Autism spectrum disorder  Childhood  Classification  International classification of functioning  Social communication Index. décimale : PER Périodiques Résumé : The Autism Classification System of Functioning: Social Communication (ACSF) describes social communication functioning levels. First developed for preschoolers with ASD, this study tests an expanded age range (2-to-18 years). The ACFS rates the child's typical and best (i.e., capacity) performance. Qualitative methods tested parent and clinician perspectives of the ACSF age expansion using content analysis. The ACSF was used twice by parents and professionals for the same child/youth. Reliabilities were assessed using weighted kappa. Content validity supported the ACSF's applicability, clarity, and usability. The ACSF adaptations did not change its original construct. Reliability were calculated from 90 parent and professional Time-1 and Time-2 ratings for children/youth (2.1-15.6 years). Results showed good-to-very good intra-rater agreement (typical) and good inter-rater agreement (capacity). En ligne : http://dx.doi.org/10.1007/s10803-022-05621-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=489 [article] Adaptation, Content Validity and Reliability of the Autism Classification System of Functioning for Social Communication: From Toddlerhood to Adolescent-Aged Children with Autism [texte imprimé] / Briano DI REZZE, Auteur ; Stephen J. GENTLES, Auteur ; Mary Jo Cooley HIDECKER, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Peter L. ROSENBAUM, Auteur ; Eric DUKU, Auteur ; Stelios GEORGIADES, Auteur ; Caroline RONCADIN, Auteur ; Hanna FANG, Auteur ; Diana J. TAJIK-PARVINCHI, Auteur ; Helena VIVEIROS, Auteur . - 2022 . - p.5150-5161. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-12 (December 2022) . - p.5150-5161 Mots-clés : Child  Adolescent  Humans  Aged  Child, Preschool  Autism Spectrum Disorder  Autistic Disorder/diagnosis  Reproducibility of Results  Communication  Parents  Autism spectrum disorder  Childhood  Classification  International classification of functioning  Social communication Index. décimale : PER Périodiques Résumé : The Autism Classification System of Functioning: Social Communication (ACSF) describes social communication functioning levels. First developed for preschoolers with ASD, this study tests an expanded age range (2-to-18 years). The ACFS rates the child's typical and best (i.e., capacity) performance. Qualitative methods tested parent and clinician perspectives of the ACSF age expansion using content analysis. The ACSF was used twice by parents and professionals for the same child/youth. Reliabilities were assessed using weighted kappa. Content validity supported the ACSF's applicability, clarity, and usability. The ACSF adaptations did not change its original construct. Reliability were calculated from 90 parent and professional Time-1 and Time-2 ratings for children/youth (2.1-15.6 years). Results showed good-to-very good intra-rater agreement (typical) and good inter-rater agreement (capacity). En ligne : http://dx.doi.org/10.1007/s10803-022-05621-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=489

Assessment of Autism Spectrum Disorder in Deaf Adults with Intellectual Disability: Feasibility and Psychometric Properties of an Adapted Version of the Autism Diagnostic Observation Schedule (ADOS-2) / Daniel HOLZINGER in Journal of Autism and Developmental Disorders, 52-7 (July 2022)  

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Brief Report: Examining Test-Retest Reliability of the Autism Diagnostic Observation Schedule (ADOS-2) Calibrated Severity Scores (CSS) / Denisse JANVIER in Journal of Autism and Developmental Disorders, 52-3 (March 2022)  

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Brief Report: Feasibility of the Probabilistic Reversal Learning Task as an Outcome Measure in an Intervention Trial for Individuals with Autism Spectrum Disorder / Lauren M. SCHMITT in Journal of Autism and Developmental Disorders, 52-9 (September 2022)  

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Brief Report: Test-Retest Reliability of Cognitive, Affective, and Spontaneous Theory of Mind Tasks Among School-Aged Children with Autism Spectrum Disorder / Melody R. ALTSCHULER in Journal of Autism and Developmental Disorders, 52-4 (April 2022)  

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Development and psychometric properties of the Clinical Anxiety Scale for People with Intellectual Disabilities (ClASP-ID) / Jessica Eliza MINGINS in Journal of Neurodevelopmental Disorders, 16 (2024)  

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