Feasibility and preliminary efficacy of behavioral activation for treatment of depression in autistic adolescents / Christina BURROUGHS ; Jessica PAPPAGIANOPOULOS ; Eleonora SADIKOVA ; Emily FUHRMANN ; Genevieve BOHAC ; Robert CROSS ; Lauren WITTE ; Gabrielle BRINKMANN ; Rachel LEMLEY ; Denis G. SUKHODOLSKY ; Micah O. MAZUREK in Autism, 28-12 (December 2024)  

Public ISBD [article]  inAutism > 28-12 (December 2024) . - p.3021-3032 Titre : Feasibility and preliminary efficacy of behavioral activation for treatment of depression in autistic adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Christina BURROUGHS, Auteur ; Jessica PAPPAGIANOPOULOS, Auteur ; Eleonora SADIKOVA, Auteur ; Emily FUHRMANN, Auteur ; Genevieve BOHAC, Auteur ; Robert CROSS, Auteur ; Lauren WITTE, Auteur ; Gabrielle BRINKMANN, Auteur ; Rachel LEMLEY, Auteur ; Denis G. SUKHODOLSKY, Auteur ; Micah O. MAZUREK, Auteur Article en page(s) : p.3021-3032 Langues : Anglais (eng) Mots-clés : anxiety  autism spectrum disorders  depression  interventions-psychosocial/behavioral  psychiatric comorbidity Index. décimale : PER Périodiques Résumé : Depression is common among autistic youth and is associated with worse quality of life in this group. Despite significant need for high-quality efficacious treatments, there has been very limited research on interventions for depression in autistic youth. This single-arm pilot study examined the feasibility and preliminary efficacy of a novel, behavior-based approach for treatment of depression symptoms in autistic adolescents without intellectual disability (i.e. Behavioral Activation for Autistic Adolescents, BA-A). BA-A is an individually delivered manualized 12-session treatment that utilizes established BA strategies and incorporates common mental health treatment adaptations for autistic young people. Of the 18 youth (11-16 years old) who enrolled, 15 completed all 12 treatment sessions, as well as pre-treatment, post-treatment, and follow-up assessment visits. Clinician treatment fidelity was quite high. Paired sample t-tests found that depression symptoms decreased pre- to post-BA-A according to multiple informants (i.e. self, caregiver, and independent evaluator), and treatment gains were maintained at 1-month follow-up. Paired sample t-tests also found that caregiver-reported anxiety symptoms and social skills improved pre-treatment to post-treatment. The results, although preliminary, indicate that BA-A may improve depression symptoms in autistic youth without intellectual disability. Furthermore, these promising findings suggest that a randomized controlled trial of BA-A is warranted. This trial was pre-registered at ClinicalTrials.gov (NCT05018169). Lay Abstract Depression is common among autistic youth and has a significant negative impact on quality of life and day-to-day functioning. Despite great need for efficacious treatments, there are currently limited research-supported interventions for depression symptoms in autistic young people. This study tested a novel, behavior-based approach or psychotherapy for treatment of depression symptoms in autistic adolescents without intellectual disability (i.e. Behavioral Activation for Autistic Adolescents, BA-A) with 15 youth (11-16 years old). BA-A is an individually delivered 12-session therapy that was developed for and to meet the needs of autistic youth with depression. Results found that autistic youth and their caregivers were able to participate in BA-A therapy sessions, and clinicians were able to deliver BA-A in accordance with the treatment manual. Notably, results demonstrated that autistic youth depression symptoms significantly improved after participating in BA-A. Furthermore, anxiety symptoms and social skills significantly improved following BA-A. En ligne : https://dx.doi.org/10.1177/13623613241252470 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=543 [article] Feasibility and preliminary efficacy of behavioral activation for treatment of depression in autistic adolescents [Texte imprimé et/ou numérique] / Christina BURROUGHS, Auteur ; Jessica PAPPAGIANOPOULOS, Auteur ; Eleonora SADIKOVA, Auteur ; Emily FUHRMANN, Auteur ; Genevieve BOHAC, Auteur ; Robert CROSS, Auteur ; Lauren WITTE, Auteur ; Gabrielle BRINKMANN, Auteur ; Rachel LEMLEY, Auteur ; Denis G. SUKHODOLSKY, Auteur ; Micah O. MAZUREK, Auteur . - p.3021-3032. Langues : Anglais (eng) in Autism > 28-12 (December 2024) . - p.3021-3032 Mots-clés : anxiety  autism spectrum disorders  depression  interventions-psychosocial/behavioral  psychiatric comorbidity Index. décimale : PER Périodiques Résumé : Depression is common among autistic youth and is associated with worse quality of life in this group. Despite significant need for high-quality efficacious treatments, there has been very limited research on interventions for depression in autistic youth. This single-arm pilot study examined the feasibility and preliminary efficacy of a novel, behavior-based approach for treatment of depression symptoms in autistic adolescents without intellectual disability (i.e. Behavioral Activation for Autistic Adolescents, BA-A). BA-A is an individually delivered manualized 12-session treatment that utilizes established BA strategies and incorporates common mental health treatment adaptations for autistic young people. Of the 18 youth (11-16 years old) who enrolled, 15 completed all 12 treatment sessions, as well as pre-treatment, post-treatment, and follow-up assessment visits. Clinician treatment fidelity was quite high. Paired sample t-tests found that depression symptoms decreased pre- to post-BA-A according to multiple informants (i.e. self, caregiver, and independent evaluator), and treatment gains were maintained at 1-month follow-up. Paired sample t-tests also found that caregiver-reported anxiety symptoms and social skills improved pre-treatment to post-treatment. The results, although preliminary, indicate that BA-A may improve depression symptoms in autistic youth without intellectual disability. Furthermore, these promising findings suggest that a randomized controlled trial of BA-A is warranted. This trial was pre-registered at ClinicalTrials.gov (NCT05018169). Lay Abstract Depression is common among autistic youth and has a significant negative impact on quality of life and day-to-day functioning. Despite great need for efficacious treatments, there are currently limited research-supported interventions for depression symptoms in autistic young people. This study tested a novel, behavior-based approach or psychotherapy for treatment of depression symptoms in autistic adolescents without intellectual disability (i.e. Behavioral Activation for Autistic Adolescents, BA-A) with 15 youth (11-16 years old). BA-A is an individually delivered 12-session therapy that was developed for and to meet the needs of autistic youth with depression. Results found that autistic youth and their caregivers were able to participate in BA-A therapy sessions, and clinicians were able to deliver BA-A in accordance with the treatment manual. Notably, results demonstrated that autistic youth depression symptoms significantly improved after participating in BA-A. Furthermore, anxiety symptoms and social skills significantly improved following BA-A. En ligne : https://dx.doi.org/10.1177/13623613241252470 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=543

Treatment of anxiety in autistic adults: A systematic review / Michelle MENEZES in Research in Autism Spectrum Disorders, 99 (November)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 99 (November) . - 102068 Titre : Treatment of anxiety in autistic adults: A systematic review Type de document : Texte imprimé et/ou numérique Auteurs : Michelle MENEZES, Auteur ; Christina HARKINS, Auteur ; Melissa F. ROBINSON, Auteur ; Jessica PAPPAGIANOPOULOS, Auteur ; Robert CROSS, Auteur ; Roma A. VASA, Auteur ; Micah O. MAZUREK, Auteur Article en page(s) : 102068 Langues : Anglais (eng) Mots-clés : Autism  ASD  Anxiety  Mental health  Treatment Index. décimale : PER Périodiques Résumé : Background Autistic adults are more likely than adults without autism spectrum disorder (ASD) to experience clinically significant anxiety. In addition, anxiety in autistic adults is associated with poorer quality of life and myriad negative outcomes (e.g., unemployment, suicidality). Therefore, this systematic review aimed to summarize and evaluate the literature on the psychotherapeutic and psychopharmacological treatment of anxiety in autistic adults to inform clinical decision-making. Method Several online databases were searched for peer-reviewed journal articles with any combination of the following terms in the abstract: (1) autism, autistic, Asperger, Asperger’s, or œpervasive developmental disorder  (2) anxiety, anxious, phobia, mutism, panic, agoraphobia, or worry and (3) treatment, intervention, trial, therapy, psychotherapy, pharmacotherapy, medication, drug, antidepressant, sedative, or anti-anxiety. Data were extracted from articles meeting the inclusion criteria, and the strength of the evidence was assessed for treatments. Results Fifteen psychosocial treatment studies, one pharmacological treatment study, and one combined psychosocial and pharmacological treatment study met the inclusion criteria. The most investigated treatment for anxiety in adults with ASD was cognitive behavioral therapy (CBT). Conclusions Few studies have investigated the treatment of anxiety in autistic adults. Additionally, findings have been inconsistent across studies regarding the potential effectiveness of particular psychosocial and pharmacological treatments. More research is certainly needed before clinically useful conclusions can be made. En ligne : https://doi.org/10.1016/j.rasd.2022.102068 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=491 [article] Treatment of anxiety in autistic adults: A systematic review [Texte imprimé et/ou numérique] / Michelle MENEZES, Auteur ; Christina HARKINS, Auteur ; Melissa F. ROBINSON, Auteur ; Jessica PAPPAGIANOPOULOS, Auteur ; Robert CROSS, Auteur ; Roma A. VASA, Auteur ; Micah O. MAZUREK, Auteur . - 102068. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 99 (November) . - 102068 Mots-clés : Autism  ASD  Anxiety  Mental health  Treatment Index. décimale : PER Périodiques Résumé : Background Autistic adults are more likely than adults without autism spectrum disorder (ASD) to experience clinically significant anxiety. In addition, anxiety in autistic adults is associated with poorer quality of life and myriad negative outcomes (e.g., unemployment, suicidality). Therefore, this systematic review aimed to summarize and evaluate the literature on the psychotherapeutic and psychopharmacological treatment of anxiety in autistic adults to inform clinical decision-making. Method Several online databases were searched for peer-reviewed journal articles with any combination of the following terms in the abstract: (1) autism, autistic, Asperger, Asperger’s, or œpervasive developmental disorder  (2) anxiety, anxious, phobia, mutism, panic, agoraphobia, or worry and (3) treatment, intervention, trial, therapy, psychotherapy, pharmacotherapy, medication, drug, antidepressant, sedative, or anti-anxiety. Data were extracted from articles meeting the inclusion criteria, and the strength of the evidence was assessed for treatments. Results Fifteen psychosocial treatment studies, one pharmacological treatment study, and one combined psychosocial and pharmacological treatment study met the inclusion criteria. The most investigated treatment for anxiety in adults with ASD was cognitive behavioral therapy (CBT). Conclusions Few studies have investigated the treatment of anxiety in autistic adults. Additionally, findings have been inconsistent across studies regarding the potential effectiveness of particular psychosocial and pharmacological treatments. More research is certainly needed before clinically useful conclusions can be made. En ligne : https://doi.org/10.1016/j.rasd.2022.102068 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=491

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