Demographic Correlates of Autism: How Do Associations Compare Between Diagnosis and a Quantitative Trait Measure? / Kristen LYALL in Autism Research, 18-3 (March 2025)  

Public ISBD [article]  inAutism Research > 18-3 (March 2025) . - p.648-659 Titre : Demographic Correlates of Autism: How Do Associations Compare Between Diagnosis and a Quantitative Trait Measure? Type de document : Texte imprimé et/ou numérique Auteurs : Kristen LYALL, Auteur ; Aisha S. DICKERSON, Auteur ; Annette M. GREEN, Auteur ; Seth FRNDAK, Auteur ; Lisa A. CROEN, Auteur ; Jennifer L. AMES, Auteur ; Lyndsay A. AVALOS, Auteur ; Judy L. ASCHNER, Auteur ; Nicole R. BUSH, Auteur ; Carlos A. CAMARGO JR, Auteur ; Viren D'SA, Auteur ; Stephen R. DAGER, Auteur ; Anne L. DUNLOP, Auteur ; Assiamira FERRARA, Auteur ; Jody M. GANIBAN, Auteur ; James E. GERN, Auteur ; Tre D. GISSANDANER, Auteur ; J. Carolyn GRAFF, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Alison E. HIPWELL, Auteur ; Tengfei MA, Auteur ; Meghan MILLER, Auteur ; Laura MURPHY, Auteur ; Margaret R. KARAGAS, Auteur ; Rachel S. KELLY, Auteur ; Amy MARGOLIS, Auteur ; Daphne KOINIS-MITCHELL, Auteur ; Cindy T. MCEVOY, Auteur ; Daniel MESSINGER, Auteur ; Ruby NGUYEN, Auteur ; Emily OKEN, Auteur ; Sally OZONOFF, Auteur ; Grier P. PAGE, Auteur ; Susan L. SCHANTZ, Auteur ; Rebecca J. SCHMIDT, Auteur ; Coral L. SHUSTER, Auteur ; Julie B. SCHWEITZER, Auteur ; Stephen J. SHEINKOPF, Auteur ; Joseph B. STANFORD, Auteur ; Cindy O. TREVINO, Auteur ; Scott T. WEISS, Auteur ; Heather E. VOLK, Auteur ; Robert M. JOSEPH, Auteur ; Outcomes PROGRAM COLLABORATORS FOR ENVIRONMENTAL INFLUENCES ON CHILD HEALTH, Auteur Article en page(s) : p.648-659 Langues : Anglais (eng) Mots-clés : autism  diagnosis  social responsiveness scale Index. décimale : PER Périodiques Résumé : ABSTRACT Prevalence of autism diagnosis has historically differed by demographic factors. Using data from 8224 participants drawn from the Environmental influences on Child Health Outcomes (ECHO) Program, we examined relationships between demographic factors and parent-reported autism-related traits as captured by the Social Responsiveness Scale (SRS; T score?>?65) and compared these to relations with parent-reported clinician diagnosis of ASD, in generalized linear mixed effects regression analyses. Results suggested lower odds of autism diagnosis, but not of SRS T?>?65, for non-Hispanic Black children (adjusted odds ratio [OR]?=?0.76, 95% CI 0.55, 1.06) relative to non-Hispanic White children. Higher maternal education was associated with reduced odds of both outcomes (OR?=?0.73, 95% CI 0.51, 1.05 for ASD autism diagnosis and 0.4, 95% CI 0.29, 0.55 for SRS score). In addition, results suggested a lower likelihood of autism diagnosis but a higher likelihood of an SRS score?>?65 in Black girls. Findings suggest lower diagnostic recognition of autism in non-Hispanic Black children, despite a similar degree of SRS-assessed autism-related traits falling in the clinically elevated range. Further work is needed to address this disparity. En ligne : https://doi.org/10.1002/aur.3296 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=550 [article] Demographic Correlates of Autism: How Do Associations Compare Between Diagnosis and a Quantitative Trait Measure? [Texte imprimé et/ou numérique] / Kristen LYALL, Auteur ; Aisha S. DICKERSON, Auteur ; Annette M. GREEN, Auteur ; Seth FRNDAK, Auteur ; Lisa A. CROEN, Auteur ; Jennifer L. AMES, Auteur ; Lyndsay A. AVALOS, Auteur ; Judy L. ASCHNER, Auteur ; Nicole R. BUSH, Auteur ; Carlos A. CAMARGO JR, Auteur ; Viren D'SA, Auteur ; Stephen R. DAGER, Auteur ; Anne L. DUNLOP, Auteur ; Assiamira FERRARA, Auteur ; Jody M. GANIBAN, Auteur ; James E. GERN, Auteur ; Tre D. GISSANDANER, Auteur ; J. Carolyn GRAFF, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Alison E. HIPWELL, Auteur ; Tengfei MA, Auteur ; Meghan MILLER, Auteur ; Laura MURPHY, Auteur ; Margaret R. KARAGAS, Auteur ; Rachel S. KELLY, Auteur ; Amy MARGOLIS, Auteur ; Daphne KOINIS-MITCHELL, Auteur ; Cindy T. MCEVOY, Auteur ; Daniel MESSINGER, Auteur ; Ruby NGUYEN, Auteur ; Emily OKEN, Auteur ; Sally OZONOFF, Auteur ; Grier P. PAGE, Auteur ; Susan L. SCHANTZ, Auteur ; Rebecca J. SCHMIDT, Auteur ; Coral L. SHUSTER, Auteur ; Julie B. SCHWEITZER, Auteur ; Stephen J. SHEINKOPF, Auteur ; Joseph B. STANFORD, Auteur ; Cindy O. TREVINO, Auteur ; Scott T. WEISS, Auteur ; Heather E. VOLK, Auteur ; Robert M. JOSEPH, Auteur ; Outcomes PROGRAM COLLABORATORS FOR ENVIRONMENTAL INFLUENCES ON CHILD HEALTH, Auteur . - p.648-659. Langues : Anglais (eng) in Autism Research > 18-3 (March 2025) . - p.648-659 Mots-clés : autism  diagnosis  social responsiveness scale Index. décimale : PER Périodiques Résumé : ABSTRACT Prevalence of autism diagnosis has historically differed by demographic factors. Using data from 8224 participants drawn from the Environmental influences on Child Health Outcomes (ECHO) Program, we examined relationships between demographic factors and parent-reported autism-related traits as captured by the Social Responsiveness Scale (SRS; T score?>?65) and compared these to relations with parent-reported clinician diagnosis of ASD, in generalized linear mixed effects regression analyses. Results suggested lower odds of autism diagnosis, but not of SRS T?>?65, for non-Hispanic Black children (adjusted odds ratio [OR]?=?0.76, 95% CI 0.55, 1.06) relative to non-Hispanic White children. Higher maternal education was associated with reduced odds of both outcomes (OR?=?0.73, 95% CI 0.51, 1.05 for ASD autism diagnosis and 0.4, 95% CI 0.29, 0.55 for SRS score). In addition, results suggested a lower likelihood of autism diagnosis but a higher likelihood of an SRS score?>?65 in Black girls. Findings suggest lower diagnostic recognition of autism in non-Hispanic Black children, despite a similar degree of SRS-assessed autism-related traits falling in the clinically elevated range. Further work is needed to address this disparity. En ligne : https://doi.org/10.1002/aur.3296 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=550

Prenatal depression and risk of child autism-related traits among participants in the Environmental influences on Child Health Outcomes program / Lyndsay A. AVALOS in Autism Research, 16-9 (September 2023)  

Public ISBD [article]  inAutism Research > 16-9 (September 2023) . - p.1825-1835 Titre : Prenatal depression and risk of child autism-related traits among participants in the Environmental influences on Child Health Outcomes program Type de document : Texte imprimé et/ou numérique Auteurs : Lyndsay A. AVALOS, Auteur ; Aruna CHANDRAN, Auteur ; Marie L. CHURCHILL, Auteur ; Xingyu GAO, Auteur ; Jennifer L. AMES, Auteur ; Sara S. NOZADI, Auteur ; Danielle ROUBINOV, Auteur ; Patricia A. BRENNAN, Auteur ; Nicole R. BUSH, Auteur ; Carlos A. CAMARGO, Auteur ; Kecia N. CARROLL, Auteur ; Camille C. CIOFFI, Auteur ; Assiamira FERRARA, Auteur ; Brandon GOLDSON, Auteur ; Monique M. HEDDERSON, Auteur ; Alison E. HIPWELL, Auteur ; Jean M. KERVER, Auteur ; Thomas G. O'CONNOR, Auteur ; Christina A. PORUCZNIK, Auteur ; Lauren C. SHUFFREY, Auteur ; Maria M. TALAVERA-BARBER, Auteur ; Rosalind J. WRIGHT, Auteur ; Yeyi ZHU, Auteur ; Lisa A. CROEN, Auteur ; program collaborators for Environmental influences on Child Health OUTCOMES, Auteur Article en page(s) : p.1825-1835 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract This study evaluated the association between prenatal depression and offspring autism-related traits. The sample comprised 33 prenatal/pediatric cohorts participating in the Environmental influences on Child Health Outcomes program who contributed information on prenatal depression and autism-related traits. Autism-related traits were assessed continuously and at the diagnostic cut-off using the Social Responsiveness Scale for children up to 12?years of age. Main analyses included 3994 parent-child pairs with prenatal depression diagnoses data; secondary analyses included 1730 parent-child pairs with depression severity data. After confounder adjustment, we observed an increase in autism-related traits among children of individuals with prenatal depression compared to those without (adjusted ?=1.31 95% CI: 0.65, 1.98). Analyses stratified by child sex documented a similar significant association among boys (a?=1.34 95%CI: 0.36, 2.32) and girls (a?=1.26 95% CI: 0.37, 2.15). Prenatal depression was also associated with increased odds of moderate to severe autism-related traits (adjusted odds ratio: 1.64, 95%CI: 1.09, 2.46), the screening threshold considered high risk of autism spectrum disorder (ASD) diagnosis. Findings highlight the importance of prenatal depression screening and preventive interventions for children of pregnant individuals with depression to support healthy development. Future research is needed to clarify whether these findings reflect overlap in genetic risk for depression and ASD-related traits or another mechanism. En ligne : https://doi.org/10.1002/aur.2988 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] Prenatal depression and risk of child autism-related traits among participants in the Environmental influences on Child Health Outcomes program [Texte imprimé et/ou numérique] / Lyndsay A. AVALOS, Auteur ; Aruna CHANDRAN, Auteur ; Marie L. CHURCHILL, Auteur ; Xingyu GAO, Auteur ; Jennifer L. AMES, Auteur ; Sara S. NOZADI, Auteur ; Danielle ROUBINOV, Auteur ; Patricia A. BRENNAN, Auteur ; Nicole R. BUSH, Auteur ; Carlos A. CAMARGO, Auteur ; Kecia N. CARROLL, Auteur ; Camille C. CIOFFI, Auteur ; Assiamira FERRARA, Auteur ; Brandon GOLDSON, Auteur ; Monique M. HEDDERSON, Auteur ; Alison E. HIPWELL, Auteur ; Jean M. KERVER, Auteur ; Thomas G. O'CONNOR, Auteur ; Christina A. PORUCZNIK, Auteur ; Lauren C. SHUFFREY, Auteur ; Maria M. TALAVERA-BARBER, Auteur ; Rosalind J. WRIGHT, Auteur ; Yeyi ZHU, Auteur ; Lisa A. CROEN, Auteur ; program collaborators for Environmental influences on Child Health OUTCOMES, Auteur . - p.1825-1835. Langues : Anglais (eng) in Autism Research > 16-9 (September 2023) . - p.1825-1835 Index. décimale : PER Périodiques Résumé : Abstract This study evaluated the association between prenatal depression and offspring autism-related traits. The sample comprised 33 prenatal/pediatric cohorts participating in the Environmental influences on Child Health Outcomes program who contributed information on prenatal depression and autism-related traits. Autism-related traits were assessed continuously and at the diagnostic cut-off using the Social Responsiveness Scale for children up to 12?years of age. Main analyses included 3994 parent-child pairs with prenatal depression diagnoses data; secondary analyses included 1730 parent-child pairs with depression severity data. After confounder adjustment, we observed an increase in autism-related traits among children of individuals with prenatal depression compared to those without (adjusted ?=1.31 95% CI: 0.65, 1.98). Analyses stratified by child sex documented a similar significant association among boys (a?=1.34 95%CI: 0.36, 2.32) and girls (a?=1.26 95% CI: 0.37, 2.15). Prenatal depression was also associated with increased odds of moderate to severe autism-related traits (adjusted odds ratio: 1.64, 95%CI: 1.09, 2.46), the screening threshold considered high risk of autism spectrum disorder (ASD) diagnosis. Findings highlight the importance of prenatal depression screening and preventive interventions for children of pregnant individuals with depression to support healthy development. Future research is needed to clarify whether these findings reflect overlap in genetic risk for depression and ASD-related traits or another mechanism. En ligne : https://doi.org/10.1002/aur.2988 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

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