Cross-sectional associations between adaptive functioning and social cognitive and neurocognitive functions in adolescents with first-episode, early-onset schizophrenia spectrum disorders / Jens Richardt Møllegaard JEPSEN in Development and Psychopathology, 36-1 (February 2024)  

Public ISBD [article]  inDevelopment and Psychopathology > 36-1 (February 2024) . - p.208-218 Titre : Cross-sectional associations between adaptive functioning and social cognitive and neurocognitive functions in adolescents with first-episode, early-onset schizophrenia spectrum disorders Type de document : texte imprimé Auteurs : Jens Richardt Møllegaard JEPSEN, Auteur ; J. RYDKJAER, Auteur ; B. FAGERLUND, Auteur ; Cecilie K. LEMVIGH, Auteur ; A.K. PAGSBERG, Auteur ; B.Y. GLENTHØJ, Auteur ; Bob ORANJE, Auteur Article en page(s) : p.208-218 Langues : Anglais (eng) Mots-clés : adaptive functioning  cognition  early-onset schizophrenia  first-episode Index. décimale : PER Périodiques Résumé : Background:Few studies have explored associations between adaptive functioning and cognition in adolescents with early-onset schizophrenia spectrum disorders (EOS).Methods:Adaptive functioning, cognition, positive, negative, and general symptoms were characterized in adolescents with EOS and healthy controls. A modified scale of negative, respectively, general symptoms was used. Bivariate analyses identified correlates of adaptive functioning to be included in multivariate analysis.Results:Adolescents with EOS showed significant impairments of social- and neurocognitive functions ( 0.86 < Cohen´s ds < 0.58) and adaptive functioning (Cohen´s d = 2.23). Visual memory, verbal working memory, processing speed, reaction time, social cognition, and modified negative and general symptoms correlated significantly with adaptive functioning. The multiple regression analysis revealed only verbal working memory as uniquely associated with adaptive functioning (explaining 22.7 % of its variance). Verbal working memory also associated significantly with adaptive functioning in the context of the nonsignificant modified negative and the significant modified general symptoms dimension.Conclusions:Adolescents with first-episode EOS had large impairments in adaptive functioning and moderate to large cognitive deficits. Verbal working memory was an important associate to concurrent adaptive functioning and may be a treatment target for trials to improve cognitive and adaptive functioning in adolescents with EOS. En ligne : https://dx.doi.org/10.1017/S0954579422001110 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=523 [article] Cross-sectional associations between adaptive functioning and social cognitive and neurocognitive functions in adolescents with first-episode, early-onset schizophrenia spectrum disorders [texte imprimé] / Jens Richardt Møllegaard JEPSEN, Auteur ; J. RYDKJAER, Auteur ; B. FAGERLUND, Auteur ; Cecilie K. LEMVIGH, Auteur ; A.K. PAGSBERG, Auteur ; B.Y. GLENTHØJ, Auteur ; Bob ORANJE, Auteur . - p.208-218. Langues : Anglais (eng) in Development and Psychopathology > 36-1 (February 2024) . - p.208-218 Mots-clés : adaptive functioning  cognition  early-onset schizophrenia  first-episode Index. décimale : PER Périodiques Résumé : Background:Few studies have explored associations between adaptive functioning and cognition in adolescents with early-onset schizophrenia spectrum disorders (EOS).Methods:Adaptive functioning, cognition, positive, negative, and general symptoms were characterized in adolescents with EOS and healthy controls. A modified scale of negative, respectively, general symptoms was used. Bivariate analyses identified correlates of adaptive functioning to be included in multivariate analysis.Results:Adolescents with EOS showed significant impairments of social- and neurocognitive functions ( 0.86 < Cohen´s ds < 0.58) and adaptive functioning (Cohen´s d = 2.23). Visual memory, verbal working memory, processing speed, reaction time, social cognition, and modified negative and general symptoms correlated significantly with adaptive functioning. The multiple regression analysis revealed only verbal working memory as uniquely associated with adaptive functioning (explaining 22.7 % of its variance). Verbal working memory also associated significantly with adaptive functioning in the context of the nonsignificant modified negative and the significant modified general symptoms dimension.Conclusions:Adolescents with first-episode EOS had large impairments in adaptive functioning and moderate to large cognitive deficits. Verbal working memory was an important associate to concurrent adaptive functioning and may be a treatment target for trials to improve cognitive and adaptive functioning in adolescents with EOS. En ligne : https://dx.doi.org/10.1017/S0954579422001110 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=523

Experiences of helplessness and fear among caregivers diagnosed with severe mental illness and co-caregivers: The Danish High Risk and Resilience Study - VIA 7 / Sinnika Birkehøj ROHD in Development and Psychopathology, 35-3 (August 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-3 (August 2023) . - p.1540-1551 Titre : Experiences of helplessness and fear among caregivers diagnosed with severe mental illness and co-caregivers: The Danish High Risk and Resilience Study - VIA 7 Type de document : texte imprimé Auteurs : Sinnika Birkehøj ROHD, Auteur ; Carsten HJORTHØJ, Auteur ; Jessica OHLAND, Auteur ; Maja GREGERSEN, Auteur ; Nicoline HEMAGER, Auteur ; Anne SØNDERGAARD, Auteur ; Camilla Austa CHRISTIANI, Auteur ; Katrine Soeborg SPANG, Auteur ; Ditte ELLERSGAARD, Auteur ; Birgitte K. BURTON, Auteur ; Marianne MELAU, Auteur ; Aja GREVE, Auteur ; Ditte L. GANTRIIS, Auteur ; Jens Richardt Møllegaard JEPSEN, Auteur ; Kerstin J. PLESSEN, Auteur ; Ole MORS, Auteur ; Merete NORDENTOFT, Auteur ; Susanne HARDER, Auteur ; Anne Amalie Elgaard THORUP, Auteur Article en page(s) : p.1540-1551 Langues : Anglais (eng) Mots-clés : caregiving and child psychopathology  children at familial high risk  level of functioning  indicators of disorganized caregiving  parental mental illness Index. décimale : PER Périodiques Résumé : This study investigates indicators of disorganized caregiving among caregivers of children who have a familial predisposition of schizophrenia spectrum psychosis (SZ) or bipolar disorder (BP), and whether indicators of disorganized caregiving are associated with the caregivers' and children s level of functioning as well as the children s internalizing and externalizing behavior problems. Indicators of disorganized caregiving were assessed with the Caregiving Helplessness Questionnaire (CHQ). Level of functioning was evaluated using the Children s Global Assessment Scale and the Personal and Social Performance Scale, while dimensional psychopathology were measured with the Child Behavior Checklist. 185 caregivers belonging to a SZ combined group (i.e., SZ-I + SZ co-caregiver), 110 caregivers to a BP combined group (i.e., BP-I + BP co-caregiver), and 184 caregivers to a population-based control group provided data on CHQ. Having a history of SZ or BP or being a co-caregiver to a parent with SZ or BP was associated with higher levels of experiences of helplessness and fear. Higher scores on helplessness were associated with lower level of functioning among caregivers and children and with children having externalizing/internalizing behavior problems. These results emphasize the need for interventions addressing indicators of disorganized caregiving in families with SZ or BP. En ligne : http://dx.doi.org/10.1017/S0954579422000281 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=511 [article] Experiences of helplessness and fear among caregivers diagnosed with severe mental illness and co-caregivers: The Danish High Risk and Resilience Study - VIA 7 [texte imprimé] / Sinnika Birkehøj ROHD, Auteur ; Carsten HJORTHØJ, Auteur ; Jessica OHLAND, Auteur ; Maja GREGERSEN, Auteur ; Nicoline HEMAGER, Auteur ; Anne SØNDERGAARD, Auteur ; Camilla Austa CHRISTIANI, Auteur ; Katrine Soeborg SPANG, Auteur ; Ditte ELLERSGAARD, Auteur ; Birgitte K. BURTON, Auteur ; Marianne MELAU, Auteur ; Aja GREVE, Auteur ; Ditte L. GANTRIIS, Auteur ; Jens Richardt Møllegaard JEPSEN, Auteur ; Kerstin J. PLESSEN, Auteur ; Ole MORS, Auteur ; Merete NORDENTOFT, Auteur ; Susanne HARDER, Auteur ; Anne Amalie Elgaard THORUP, Auteur . - p.1540-1551. Langues : Anglais (eng) in Development and Psychopathology > 35-3 (August 2023) . - p.1540-1551 Mots-clés : caregiving and child psychopathology  children at familial high risk  level of functioning  indicators of disorganized caregiving  parental mental illness Index. décimale : PER Périodiques Résumé : This study investigates indicators of disorganized caregiving among caregivers of children who have a familial predisposition of schizophrenia spectrum psychosis (SZ) or bipolar disorder (BP), and whether indicators of disorganized caregiving are associated with the caregivers' and children s level of functioning as well as the children s internalizing and externalizing behavior problems. Indicators of disorganized caregiving were assessed with the Caregiving Helplessness Questionnaire (CHQ). Level of functioning was evaluated using the Children s Global Assessment Scale and the Personal and Social Performance Scale, while dimensional psychopathology were measured with the Child Behavior Checklist. 185 caregivers belonging to a SZ combined group (i.e., SZ-I + SZ co-caregiver), 110 caregivers to a BP combined group (i.e., BP-I + BP co-caregiver), and 184 caregivers to a population-based control group provided data on CHQ. Having a history of SZ or BP or being a co-caregiver to a parent with SZ or BP was associated with higher levels of experiences of helplessness and fear. Higher scores on helplessness were associated with lower level of functioning among caregivers and children and with children having externalizing/internalizing behavior problems. These results emphasize the need for interventions addressing indicators of disorganized caregiving in families with SZ or BP. En ligne : http://dx.doi.org/10.1017/S0954579422000281 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=511

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