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Auteur John P. NEWNHAM
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Documents disponibles écrits par cet auteur (7)
Faire une suggestion Affiner la rechercheAre Prenatal Ultrasound Scans Associated with the Autism Phenotype? Follow-up of a Randomised Controlled Trial / Yonit K. STOCH in Journal of Autism and Developmental Disorders, 42-12 (December 2012)
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Titre : Are Prenatal Ultrasound Scans Associated with the Autism Phenotype? Follow-up of a Randomised Controlled Trial Type de document : texte imprimé Auteurs : Yonit K. STOCH, Auteur ; Cori J. WILLIAMS, Auteur ; Joanna GRANICH, Auteur ; Anna HUNT, Auteur ; Lou I. LANDAU, Auteur ; John P. NEWNHAM, Auteur ; Andrew J.O. WHITEHOUSE, Auteur Article en page(s) : p.2693-2701 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Autism Prenatal Ultrasonography Obstetric Environment Index. décimale : PER Périodiques Résumé : An existing randomised controlled trial was used to investigate whether multiple ultrasound scans may be associated with the autism phenotype. From 2,834 single pregnancies, 1,415 were selected at random to receive ultrasound imaging and continuous wave Doppler flow studies at five points throughout pregnancy (Intensive) and 1,419 to receive a single imaging scan at 18 weeks (Regular), with further scans only as indicated on clinical grounds. There was no significant difference in the rate of Autism Spectrum Disorder between the Regular (9/1,125, 0.8 %) and Intensive (7/1,167, 0.6 %) groups, nor a difference between groups in the level of autistic-like traits in early adulthood. There is no clear link between the frequency and timing of prenatal ultrasound scans and the autism phenotype. En ligne : http://dx.doi.org/10.1007/s10803-012-1526-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=184
in Journal of Autism and Developmental Disorders > 42-12 (December 2012) . - p.2693-2701[article] Are Prenatal Ultrasound Scans Associated with the Autism Phenotype? Follow-up of a Randomised Controlled Trial [texte imprimé] / Yonit K. STOCH, Auteur ; Cori J. WILLIAMS, Auteur ; Joanna GRANICH, Auteur ; Anna HUNT, Auteur ; Lou I. LANDAU, Auteur ; John P. NEWNHAM, Auteur ; Andrew J.O. WHITEHOUSE, Auteur . - p.2693-2701.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-12 (December 2012) . - p.2693-2701
Mots-clés : Autism spectrum disorder Autism Prenatal Ultrasonography Obstetric Environment Index. décimale : PER Périodiques Résumé : An existing randomised controlled trial was used to investigate whether multiple ultrasound scans may be associated with the autism phenotype. From 2,834 single pregnancies, 1,415 were selected at random to receive ultrasound imaging and continuous wave Doppler flow studies at five points throughout pregnancy (Intensive) and 1,419 to receive a single imaging scan at 18 weeks (Regular), with further scans only as indicated on clinical grounds. There was no significant difference in the rate of Autism Spectrum Disorder between the Regular (9/1,125, 0.8 %) and Intensive (7/1,167, 0.6 %) groups, nor a difference between groups in the level of autistic-like traits in early adulthood. There is no clear link between the frequency and timing of prenatal ultrasound scans and the autism phenotype. En ligne : http://dx.doi.org/10.1007/s10803-012-1526-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=184 Brief Report: A Preliminary Study of Fetal Head Circumference Growth in Autism Spectrum Disorder / Andrew J.O. WHITEHOUSE in Journal of Autism and Developmental Disorders, 41-1 (January 2011)
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Titre : Brief Report: A Preliminary Study of Fetal Head Circumference Growth in Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Andrew J.O. WHITEHOUSE, Auteur ; Martha HICKEY, Auteur ; Fiona J. STANLEY, Auteur ; John P. NEWNHAM, Auteur ; Craig E. PENNELL, Auteur Année de publication : 2011 Article en page(s) : p.122-129 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Brain growth Head circumference Fetus Ultrasound Index. décimale : PER Périodiques Résumé : Fetal head circumference (HC) growth was examined prospectively in children with autism spectrum disorder (ASD). ASD participants (N = 14) were each matched with four control participants (N = 56) on a range of parameters known to influence fetal growth. HC was measured using ultrasonography at approximately 18 weeks gestation and again at birth using a paper tape-measure. Overall body size was indexed by fetal femur-length and birth length. There was no between-groups difference in head circumference at either time-point. While a small number of children with ASD had disproportionately large head circumference relative to body size at both time-points, the between-groups difference did not reach statistical significance in this small sample. These preliminary findings suggest that further investigation of fetal growth in ASD is warranted. En ligne : http://dx.doi.org/10.1007/s10803-010-1019-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=114
in Journal of Autism and Developmental Disorders > 41-1 (January 2011) . - p.122-129[article] Brief Report: A Preliminary Study of Fetal Head Circumference Growth in Autism Spectrum Disorder [texte imprimé] / Andrew J.O. WHITEHOUSE, Auteur ; Martha HICKEY, Auteur ; Fiona J. STANLEY, Auteur ; John P. NEWNHAM, Auteur ; Craig E. PENNELL, Auteur . - 2011 . - p.122-129.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 41-1 (January 2011) . - p.122-129
Mots-clés : Autism spectrum disorder Brain growth Head circumference Fetus Ultrasound Index. décimale : PER Périodiques Résumé : Fetal head circumference (HC) growth was examined prospectively in children with autism spectrum disorder (ASD). ASD participants (N = 14) were each matched with four control participants (N = 56) on a range of parameters known to influence fetal growth. HC was measured using ultrasonography at approximately 18 weeks gestation and again at birth using a paper tape-measure. Overall body size was indexed by fetal femur-length and birth length. There was no between-groups difference in head circumference at either time-point. While a small number of children with ASD had disproportionately large head circumference relative to body size at both time-points, the between-groups difference did not reach statistical significance in this small sample. These preliminary findings suggest that further investigation of fetal growth in ASD is warranted. En ligne : http://dx.doi.org/10.1007/s10803-010-1019-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=114 Erratum - Prenatal stress and risk of behavioral morbidity from age 2 to 14 years: The influence of the number, type, and timing of stressful life events / Monique ROBINSON in Development and Psychopathology, 24-1 (January 2012)
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Titre : Erratum - Prenatal stress and risk of behavioral morbidity from age 2 to 14 years: The influence of the number, type, and timing of stressful life events Type de document : texte imprimé Auteurs : Monique ROBINSON, Auteur ; Eugen MATTES, Auteur ; Wendy H. ODDY, Auteur ; Craig E. PENNELL, Auteur ; Anke VAN EEKELEN, Auteur ; Neil J. MCLEAN, Auteur ; Peter JACOBY, Auteur ; Jianghong LI, Auteur ; Nicholas H. DE KLERK, Auteur ; Stephen R. ZUBRICK, Auteur ; Fiona J. STANLEY, Auteur ; John P. NEWNHAM, Auteur Année de publication : 2012 Article en page(s) : p.333 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1017/S0954579411000861 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=152
in Development and Psychopathology > 24-1 (January 2012) . - p.333[article] Erratum - Prenatal stress and risk of behavioral morbidity from age 2 to 14 years: The influence of the number, type, and timing of stressful life events [texte imprimé] / Monique ROBINSON, Auteur ; Eugen MATTES, Auteur ; Wendy H. ODDY, Auteur ; Craig E. PENNELL, Auteur ; Anke VAN EEKELEN, Auteur ; Neil J. MCLEAN, Auteur ; Peter JACOBY, Auteur ; Jianghong LI, Auteur ; Nicholas H. DE KLERK, Auteur ; Stephen R. ZUBRICK, Auteur ; Fiona J. STANLEY, Auteur ; John P. NEWNHAM, Auteur . - 2012 . - p.333.
Langues : Anglais (eng)
in Development and Psychopathology > 24-1 (January 2012) . - p.333
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1017/S0954579411000861 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=152 Maternal pre-pregnancy weight and autistic-like traits among offspring in the general population / Kandice J. VARCIN in Autism Research, 12-1 (January 2019)
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Titre : Maternal pre-pregnancy weight and autistic-like traits among offspring in the general population Type de document : texte imprimé Auteurs : Kandice J. VARCIN, Auteur ; John P. NEWNHAM, Auteur ; Andrew J.O. WHITEHOUSE, Auteur Article en page(s) : p.80-88 Langues : Anglais (eng) Mots-clés : autism spectrum disorder body mass index maternal obesity prenatal Index. décimale : PER Périodiques Résumé : There is an emerging body of evidence demonstrating that maternal obesity at the time of conception increases the risk for Autism Spectrum Disorders (ASD) among offspring. We explored whether pre-pregnancy weight was related to autistic-like traits among offspring not diagnosed with ASD. A large sample of women, recruited during the second trimester of pregnancy, had their height measured and reported their pre-pregnancy weight. These measurements were then converted to a Body Mass Index (BMI) using the formula: (weight in kilograms)/(height in metres(2) ). At 19-20 years of age, 1238 offspring of these women completed a measure of autistic-like traits, the Autism-Spectrum Quotient (AQ). Regression analyses identified a positive association between increasing maternal pre-pregnancy BMI and increasing AQ Total Score amongst offspring; this association was maintained even after controlling for a range of variables including maternal/obstetric factors (age at conception, education, smoking, alcohol consumption, hypertensive diseases, diabetes, threatened abortion), paternal BMI at pregnancy, and child factors (parity, sex) (P < .01, R(2) =.03). Chi-square analyses found that women with pre-pregnancy obesity (BMI >/= 30) were more likely to have offspring with high scores (>/=26) on the AQ (P = .01). Follow-up binary logistic regression analyses also accounting for the same obstetric and sociodemographic variables found that the offspring of women with pre-pregnancy obesity were at a statistically significantly increased risk of having high scores (>/=26) on the AQ (OR: 2.80; 95% CI: 1.06, 7.43). This study provides further evidence that maternal pre-pregnancy obesity is associated with autism-like behaviors in offspring. Autism Research 2019, 12: 80-88. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: The current study explored whether pre-pregnancy weight was related to autistic-like traits among offspring not diagnosed with ASD. We found that pre-pregnancy body mass index in women is associated with the amount of autistic-like traits in their children in early adulthood. Specifically, women who were obese at the time of conception were more likely to have a child who had high levels of autistic-like traits in early adulthood. En ligne : http://dx.doi.org/10.1002/aur.1973 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=376
in Autism Research > 12-1 (January 2019) . - p.80-88[article] Maternal pre-pregnancy weight and autistic-like traits among offspring in the general population [texte imprimé] / Kandice J. VARCIN, Auteur ; John P. NEWNHAM, Auteur ; Andrew J.O. WHITEHOUSE, Auteur . - p.80-88.
Langues : Anglais (eng)
in Autism Research > 12-1 (January 2019) . - p.80-88
Mots-clés : autism spectrum disorder body mass index maternal obesity prenatal Index. décimale : PER Périodiques Résumé : There is an emerging body of evidence demonstrating that maternal obesity at the time of conception increases the risk for Autism Spectrum Disorders (ASD) among offspring. We explored whether pre-pregnancy weight was related to autistic-like traits among offspring not diagnosed with ASD. A large sample of women, recruited during the second trimester of pregnancy, had their height measured and reported their pre-pregnancy weight. These measurements were then converted to a Body Mass Index (BMI) using the formula: (weight in kilograms)/(height in metres(2) ). At 19-20 years of age, 1238 offspring of these women completed a measure of autistic-like traits, the Autism-Spectrum Quotient (AQ). Regression analyses identified a positive association between increasing maternal pre-pregnancy BMI and increasing AQ Total Score amongst offspring; this association was maintained even after controlling for a range of variables including maternal/obstetric factors (age at conception, education, smoking, alcohol consumption, hypertensive diseases, diabetes, threatened abortion), paternal BMI at pregnancy, and child factors (parity, sex) (P < .01, R(2) =.03). Chi-square analyses found that women with pre-pregnancy obesity (BMI >/= 30) were more likely to have offspring with high scores (>/=26) on the AQ (P = .01). Follow-up binary logistic regression analyses also accounting for the same obstetric and sociodemographic variables found that the offspring of women with pre-pregnancy obesity were at a statistically significantly increased risk of having high scores (>/=26) on the AQ (OR: 2.80; 95% CI: 1.06, 7.43). This study provides further evidence that maternal pre-pregnancy obesity is associated with autism-like behaviors in offspring. Autism Research 2019, 12: 80-88. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: The current study explored whether pre-pregnancy weight was related to autistic-like traits among offspring not diagnosed with ASD. We found that pre-pregnancy body mass index in women is associated with the amount of autistic-like traits in their children in early adulthood. Specifically, women who were obese at the time of conception were more likely to have a child who had high levels of autistic-like traits in early adulthood. En ligne : http://dx.doi.org/10.1002/aur.1973 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=376 Pre- and postnatal influences on preschool mental health: a large-scale cohort study / Monique ROBINSON in Journal of Child Psychology and Psychiatry, 49-10 (October 2008)
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Titre : Pre- and postnatal influences on preschool mental health: a large-scale cohort study Type de document : texte imprimé Auteurs : Monique ROBINSON, Auteur ; Fiona J. STANLEY, Auteur ; John P. NEWNHAM, Auteur ; Stephen R. ZUBRICK, Auteur ; Sven R. SILBURN, Auteur ; Nicholas H. DE KLERK, Auteur ; Garth E. KENDALL, Auteur ; Jianghong LI, Auteur ; Wendy H. ODDY, Auteur ; Eugen MATTES, Auteur Année de publication : 2008 Article en page(s) : p.1118-1128 Langues : Anglais (eng) Mots-clés : Mental-health pre-school-children behavioural-development Raine-Study CBCL Index. décimale : PER Périodiques Résumé : Background: Methodological challenges such as confounding have made the study of the early determinants of mental health morbidity problematic. This study aims to address these challenges in investigating antenatal, perinatal and postnatal risk factors for the development of mental health problems in pre-school children in a cohort of Western Australian children.
Methods: The Raine Study is a prospective cohort study of 2,868 live born children involving 2,979 pregnant women recruited at 18 weeks gestation. Children were followed up at age two and five years. The Child Behaviour Checklist (CBCL) was used to measure child mental health with clinical cut-points, including internalising (withdrawn/depressed) and externalising (aggressive/destructive) behaviours (n = 1707).
Results: Multinomial logistic regression analysis showed that the significant risk factors for behaviour problems at age two were the maternal experience of multiple stress events in pregnancy (OR = 1.20, 95% CI = 1.06, 1.37), smoking during pregnancy (OR = 1.30, 95% CI = 1.06, 1.59) and maternal ethnicity (OR = 3.34, 95% CI = 1.61, 6.96). At age five the experience of multiple stress events (OR = 1.17, 95% CI = 1.08, 1.27), cigarette smoking (OR = 1.19, 95% CI = 1.03, 1.37), male gender (OR = 1.43, 95% CI = 1.02, 2.00), breastfeeding for a shorter time (OR = .97, 95% CI = .94, .99) and multiple baby blues symptoms (OR = 1.08, 95% CI = 1.02, 1.14) were significant predictors of mental health problems.
Conclusions: Early childhood mental health is significantly affected by prenatal events in addition to the child's later environment. Interventions targeting adverse prenatal, perinatal and postnatal influences can be expected to improve mental health outcomes for children in the early years.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01955.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=607
in Journal of Child Psychology and Psychiatry > 49-10 (October 2008) . - p.1118-1128[article] Pre- and postnatal influences on preschool mental health: a large-scale cohort study [texte imprimé] / Monique ROBINSON, Auteur ; Fiona J. STANLEY, Auteur ; John P. NEWNHAM, Auteur ; Stephen R. ZUBRICK, Auteur ; Sven R. SILBURN, Auteur ; Nicholas H. DE KLERK, Auteur ; Garth E. KENDALL, Auteur ; Jianghong LI, Auteur ; Wendy H. ODDY, Auteur ; Eugen MATTES, Auteur . - 2008 . - p.1118-1128.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 49-10 (October 2008) . - p.1118-1128
Mots-clés : Mental-health pre-school-children behavioural-development Raine-Study CBCL Index. décimale : PER Périodiques Résumé : Background: Methodological challenges such as confounding have made the study of the early determinants of mental health morbidity problematic. This study aims to address these challenges in investigating antenatal, perinatal and postnatal risk factors for the development of mental health problems in pre-school children in a cohort of Western Australian children.
Methods: The Raine Study is a prospective cohort study of 2,868 live born children involving 2,979 pregnant women recruited at 18 weeks gestation. Children were followed up at age two and five years. The Child Behaviour Checklist (CBCL) was used to measure child mental health with clinical cut-points, including internalising (withdrawn/depressed) and externalising (aggressive/destructive) behaviours (n = 1707).
Results: Multinomial logistic regression analysis showed that the significant risk factors for behaviour problems at age two were the maternal experience of multiple stress events in pregnancy (OR = 1.20, 95% CI = 1.06, 1.37), smoking during pregnancy (OR = 1.30, 95% CI = 1.06, 1.59) and maternal ethnicity (OR = 3.34, 95% CI = 1.61, 6.96). At age five the experience of multiple stress events (OR = 1.17, 95% CI = 1.08, 1.27), cigarette smoking (OR = 1.19, 95% CI = 1.03, 1.37), male gender (OR = 1.43, 95% CI = 1.02, 2.00), breastfeeding for a shorter time (OR = .97, 95% CI = .94, .99) and multiple baby blues symptoms (OR = 1.08, 95% CI = 1.02, 1.14) were significant predictors of mental health problems.
Conclusions: Early childhood mental health is significantly affected by prenatal events in addition to the child's later environment. Interventions targeting adverse prenatal, perinatal and postnatal influences can be expected to improve mental health outcomes for children in the early years.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01955.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=607 Prenatal stress and risk of behavioral morbidity from age 2 to 14 years: The influence of the number, type, and timing of stressful life events / Monique ROBINSON in Development and Psychopathology, 23-2 (May 2011)
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PermalinkThe impact of life stress on adult depression and anxiety is dependent on gender and timing of exposure / Carly E. HERBISON in Development and Psychopathology, 29-4 (October 2017)
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