Autistic symptomatology and language ability in autism spectrum disorder and specific language impairment / Tom LOUCAS in Journal of Child Psychology and Psychiatry, 49-11 (November 2008)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 49-11 (November 2008) . - p.1184-1192 Titre : Autistic symptomatology and language ability in autism spectrum disorder and specific language impairment Type de document : texte imprimé Auteurs : Tom LOUCAS, Auteur ; Tony CHARMAN, Auteur ; Emily SIMONOFF, Auteur ; Andrew PICKLES, Auteur ; Gillian BAIRD, Auteur ; Susie CHANDLER, Auteur ; David MELDRUM, Auteur Année de publication : 2008 Article en page(s) : p.1184-1192 Langues : Anglais (eng) Mots-clés : Autistic-disorder specific-language-impairment SNAP-cohort Index. décimale : PER Périodiques Résumé : Background: Autism spectrum disorders (ASD) and specific language impairment (SLI) are common developmental disorders characterised by deficits in language and communication. The nature of the relationship between them continues to be a matter of debate. This study investigates whether the co-occurrence of ASD and language impairment is associated with differences in severity or pattern of autistic symptomatology or language profile. Methods: Participants (N = 97) were drawn from a total population cohort of 56,946 screened as part of study to ascertain the prevalence of ASD, aged 9 to 14 years. All children received an ICD-10 clinical diagnosis of ASD or No ASD. Children with nonverbal IQ ≥80 were divided into those with a language impairment (language score of 77 or less) and those without, creating three groups: children with ASD and a language impairment (ALI; N = 41), those with ASD and but no language impairment (ANL; N = 31) and those with language impairment but no ASD (SLI; N = 25). Results: Children with ALI did not show more current autistic symptoms than those with ANL. Children with SLI were well below the threshold for ASD. Their social adaptation was higher than the ASD groups, but still nearly 2 SD below average. In ALI the combination of ASD and language impairment was associated with weaker functional communication and more severe receptive language difficulties than those found in SLI. Receptive and expressive language were equally impaired in ALI, whereas in SLI receptive language was stronger than expressive. Conclusions: Co-occurrence of ASD and language impairment is not associated with increased current autistic symptomatology but appears to be associated with greater impairment in receptive language and functional communication. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01951.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=633 [article] Autistic symptomatology and language ability in autism spectrum disorder and specific language impairment [texte imprimé] / Tom LOUCAS, Auteur ; Tony CHARMAN, Auteur ; Emily SIMONOFF, Auteur ; Andrew PICKLES, Auteur ; Gillian BAIRD, Auteur ; Susie CHANDLER, Auteur ; David MELDRUM, Auteur . - 2008 . - p.1184-1192. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 49-11 (November 2008) . - p.1184-1192 Mots-clés : Autistic-disorder specific-language-impairment SNAP-cohort Index. décimale : PER Périodiques Résumé : Background: Autism spectrum disorders (ASD) and specific language impairment (SLI) are common developmental disorders characterised by deficits in language and communication. The nature of the relationship between them continues to be a matter of debate. This study investigates whether the co-occurrence of ASD and language impairment is associated with differences in severity or pattern of autistic symptomatology or language profile. Methods: Participants (N = 97) were drawn from a total population cohort of 56,946 screened as part of study to ascertain the prevalence of ASD, aged 9 to 14 years. All children received an ICD-10 clinical diagnosis of ASD or No ASD. Children with nonverbal IQ ≥80 were divided into those with a language impairment (language score of 77 or less) and those without, creating three groups: children with ASD and a language impairment (ALI; N = 41), those with ASD and but no language impairment (ANL; N = 31) and those with language impairment but no ASD (SLI; N = 25). Results: Children with ALI did not show more current autistic symptoms than those with ANL. Children with SLI were well below the threshold for ASD. Their social adaptation was higher than the ASD groups, but still nearly 2 SD below average. In ALI the combination of ASD and language impairment was associated with weaker functional communication and more severe receptive language difficulties than those found in SLI. Receptive and expressive language were equally impaired in ALI, whereas in SLI receptive language was stronger than expressive. Conclusions: Co-occurrence of ASD and language impairment is not associated with increased current autistic symptomatology but appears to be associated with greater impairment in receptive language and functional communication. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01951.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=633

Bengali translation and characterisation of four cognitive and trait measures for autism spectrum conditions in India / Alokananda RUDRA in Molecular Autism, 7 (2016)  

Public ISBD [article]  inMolecular Autism > 7 (2016) . - 50p. Titre : Bengali translation and characterisation of four cognitive and trait measures for autism spectrum conditions in India Type de document : texte imprimé Auteurs : Alokananda RUDRA, Auteur ; Jai Ranjan RAM, Auteur ; Tom LOUCAS, Auteur ; Matthew K. BELMONTE, Auteur ; Bhismadev CHAKRABARTI, Auteur Article en page(s) : 50p. Langues : Anglais (eng) Mots-clés : Adolescent  Autism Spectrum Disorder/physiopathology/psychology  Case-Control Studies  Child  Cognition/physiology  Cross-Cultural Comparison  Empathy  Facial Expression  Female  Humans  India  Intelligence Tests/standards  Language  Male  Regression Analysis  Social Skills  Surveys and Questionnaires  Theory of Mind  Translations  Assessment  Autism  Behaviour  Bengali  Central coherence  Perceptual construal  Theory of mind  Translation  Validity Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism is characterised by atypical social-communicative behaviour and restricted range of interests and repetitive behaviours. These features exist in a continuum in the general population. Behavioural measures validated across cultures and languages are required to quantify the dimensional traits of autism in these social and non-social domains. Bengali is the seventh most spoken language in the world. However, there is a serious dearth of data on standard measures of autism-related social and visual cognition in Bengali. METHODS: Bengali translations of two measures related to social-communicative functioning (the Children's Reading the Mind in the Eyes Test (RMET) and a facial emotion recognition test with stimuli taken from the Karolinska Directed Emotional Faces database), one measure of visual perceptual disembedding (the Embedded Figures Test), and a questionnaire measure (the Children's Empathy Quotient) were tested in 25 children with autism spectrum conditions (ASC) and 26 control children (mean age = 10.7 years) in Kolkata, India. Group differences were analysed by t test and multiple regression (after accounting for potential effects of gender, IQ, and age). RESULTS: Behavioural and trait measures were associated with group differences in the expected directions: ASC children scored lower on the Children's Empathy Quotient and the RMET, as well as on facial emotion recognition, but were faster and more accurate on the Embedded Figures Test. Distributional properties of these measures within groups are similar to those reported in Western countries. CONCLUSIONS: These results provide an empirical demonstration of cross-cultural generalisability and applicability of these standard behavioural and trait measures related to autism, in a major world language. En ligne : http://dx.doi.org/10.1186/s13229-016-0111-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=329 [article] Bengali translation and characterisation of four cognitive and trait measures for autism spectrum conditions in India [texte imprimé] / Alokananda RUDRA, Auteur ; Jai Ranjan RAM, Auteur ; Tom LOUCAS, Auteur ; Matthew K. BELMONTE, Auteur ; Bhismadev CHAKRABARTI, Auteur . - 50p. Langues : Anglais (eng) in Molecular Autism > 7 (2016) . - 50p. Mots-clés : Adolescent  Autism Spectrum Disorder/physiopathology/psychology  Case-Control Studies  Child  Cognition/physiology  Cross-Cultural Comparison  Empathy  Facial Expression  Female  Humans  India  Intelligence Tests/standards  Language  Male  Regression Analysis  Social Skills  Surveys and Questionnaires  Theory of Mind  Translations  Assessment  Autism  Behaviour  Bengali  Central coherence  Perceptual construal  Theory of mind  Translation  Validity Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism is characterised by atypical social-communicative behaviour and restricted range of interests and repetitive behaviours. These features exist in a continuum in the general population. Behavioural measures validated across cultures and languages are required to quantify the dimensional traits of autism in these social and non-social domains. Bengali is the seventh most spoken language in the world. However, there is a serious dearth of data on standard measures of autism-related social and visual cognition in Bengali. METHODS: Bengali translations of two measures related to social-communicative functioning (the Children's Reading the Mind in the Eyes Test (RMET) and a facial emotion recognition test with stimuli taken from the Karolinska Directed Emotional Faces database), one measure of visual perceptual disembedding (the Embedded Figures Test), and a questionnaire measure (the Children's Empathy Quotient) were tested in 25 children with autism spectrum conditions (ASC) and 26 control children (mean age = 10.7 years) in Kolkata, India. Group differences were analysed by t test and multiple regression (after accounting for potential effects of gender, IQ, and age). RESULTS: Behavioural and trait measures were associated with group differences in the expected directions: ASC children scored lower on the Children's Empathy Quotient and the RMET, as well as on facial emotion recognition, but were faster and more accurate on the Embedded Figures Test. Distributional properties of these measures within groups are similar to those reported in Western countries. CONCLUSIONS: These results provide an empirical demonstration of cross-cultural generalisability and applicability of these standard behavioural and trait measures related to autism, in a major world language. En ligne : http://dx.doi.org/10.1186/s13229-016-0111-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=329

Book review: Assessment of Autism Spectrum Disorders by S. Goldstein, J.A. Naglieri and S. Ozonoff (Eds). London: Guildford Press, 2009. ISBN 978—1—59385 —983—1. £27.45 hdk. 384 pp / Tom LOUCAS in Autism, 13-5 (September 2009)  

Public ISBD [article]  inAutism > 13-5 (September 2009) . - p.539-541 Titre : Book review: Assessment of Autism Spectrum Disorders by S. Goldstein, J.A. Naglieri and S. Ozonoff (Eds). London: Guildford Press, 2009. ISBN 978—1—59385 —983—1. £27.45 hdk. 384 pp Type de document : texte imprimé Auteurs : Tom LOUCAS, Auteur Année de publication : 2009 Article en page(s) : p.539-541 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1177/1362361309346113 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=834 [article] Book review: Assessment of Autism Spectrum Disorders by S. Goldstein, J.A. Naglieri and S. Ozonoff (Eds). London: Guildford Press, 2009. ISBN 978—1—59385 —983—1. £27.45 hdk. 384 pp [texte imprimé] / Tom LOUCAS, Auteur . - 2009 . - p.539-541. Langues : Anglais (eng) in Autism > 13-5 (September 2009) . - p.539-541 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1177/1362361309346113 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=834

Elephants in Pyjamas: Testing the Weak Central Coherence Account of Autism Spectrum Disorders Using a Syntactic Disambiguation Task / N.G. RICHES in Journal of Autism and Developmental Disorders, 46-1 (January 2016)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 46-1 (January 2016) . - p.155-163 Titre : Elephants in Pyjamas: Testing the Weak Central Coherence Account of Autism Spectrum Disorders Using a Syntactic Disambiguation Task Type de document : texte imprimé Auteurs : N.G. RICHES, Auteur ; Tom LOUCAS, Auteur ; Gillian BAIRD, Auteur ; Tony CHARMAN, Auteur ; Emily SIMONOFF, Auteur Année de publication : 2016 Article en page(s) : p.155-163 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders (ASD)  Developmental language impairment  Adolescents Index. décimale : PER Périodiques Résumé : According to the weak central coherence (CC) account individuals with autism spectrum disorders (ASD) exhibit enhanced local processing and weak part-whole integration. CC was investigated in the verbal domain. Adolescents, recruited using a 2 (ASD status) by 2 (language impairment status) design, completed an aural forced choice comprehension task involving syntactically ambiguous sentences. Half the picture targets depicted the least plausible interpretation, resulting in longer RTs across groups. These were assumed to reflect local processing. There was no ASD by plausibility interaction and consequently little evidence for weak CC in the verbal domain when conceptualised as enhanced local processing. Furthermore, there was little evidence that the processing of syntactically ambiguous sentences differed as a function of ASD or language-impairment status. En ligne : http://dx.doi.org/10.1007/s10803-015-2560-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278 [article] Elephants in Pyjamas: Testing the Weak Central Coherence Account of Autism Spectrum Disorders Using a Syntactic Disambiguation Task [texte imprimé] / N.G. RICHES, Auteur ; Tom LOUCAS, Auteur ; Gillian BAIRD, Auteur ; Tony CHARMAN, Auteur ; Emily SIMONOFF, Auteur . - 2016 . - p.155-163. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 46-1 (January 2016) . - p.155-163 Mots-clés : Autism spectrum disorders (ASD)  Developmental language impairment  Adolescents Index. décimale : PER Périodiques Résumé : According to the weak central coherence (CC) account individuals with autism spectrum disorders (ASD) exhibit enhanced local processing and weak part-whole integration. CC was investigated in the verbal domain. Adolescents, recruited using a 2 (ASD status) by 2 (language impairment status) design, completed an aural forced choice comprehension task involving syntactically ambiguous sentences. Half the picture targets depicted the least plausible interpretation, resulting in longer RTs across groups. These were assumed to reflect local processing. There was no ASD by plausibility interaction and consequently little evidence for weak CC in the verbal domain when conceptualised as enhanced local processing. Furthermore, there was little evidence that the processing of syntactically ambiguous sentences differed as a function of ASD or language-impairment status. En ligne : http://dx.doi.org/10.1007/s10803-015-2560-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278

Gut Permeability in Autism Spectrum Disorders / Neil R. DALTON in Autism Research, 7-3 (June 2014)  

Public ISBD [article]  inAutism Research > 7-3 (June 2014) . - p.305-313 Titre : Gut Permeability in Autism Spectrum Disorders Type de document : texte imprimé Auteurs : Neil R. DALTON, Auteur ; Susie CHANDLER, Auteur ; Charles TURNER, Auteur ; Tony CHARMAN, Auteur ; Andrew PICKLES, Auteur ; Tom LOUCAS, Auteur ; Emily SIMONOFF, Auteur ; Peter SULLIVAN, Auteur ; Gillian BAIRD, Auteur Article en page(s) : p.305-313 Langues : Anglais (eng) Mots-clés : autism  autism spectrum disorders  gut permeability  lactulose/mannitol ratio Index. décimale : PER Périodiques Résumé : Objective To test whether gut permeability is increased in autism spectrum disorders (ASD) by evaluating gut permeability in a population-derived cohort of children with ASD compared with age- and intelligence quotient-matched controls without ASD but with special educational needs (SEN). Patients and Methods One hundred thirty-three children aged 10–14 years, 103 with ASD and 30 with SEN, were given an oral test dose of mannitol and lactulose and urine collected for 6 hr. Gut permeability was assessed by measuring the urine lactulose/mannitol (L/M) recovery ratio by electrospray mass spectrometry-mass spectrometry. The ASD group was subcategorized for comparison into those without (n = 83) and with (n = 20) regression. Results There was no significant difference in L/M recovery ratio (mean (95% confidence interval)) between the groups with ASD: 0.015 (0.013–0.018), and SEN: 0.014 (0.009–0.019), nor in lactulose, mannitol, or creatinine recovery. No significant differences were observed in any parameter for the regressed versus non-regressed ASD groups. Results were consistent with previously published normal ranges. Eleven children (9/103 = 8.7% ASD and 2/30 = 6.7% SEN) had L/M recovery ratio  0.03 (the accepted normal range cut-off), of whom two (one ASD and one SEN) had more definitely pathological L/M recovery ratios  0.04. Conclusion There is no statistically significant group difference in small intestine permeability in a population cohort-derived group of children with ASD compared with a control group with SEN. Of the two children (one ASD and one SEN) with an L/M recovery ratio of  0.04, one had undiagnosed asymptomatic celiac disease (ASD) and the other (SEN) past extensive surgery for gastroschisis. Autism Res 2014, 7: 305–313. © 2013 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1350 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=235 [article] Gut Permeability in Autism Spectrum Disorders [texte imprimé] / Neil R. DALTON, Auteur ; Susie CHANDLER, Auteur ; Charles TURNER, Auteur ; Tony CHARMAN, Auteur ; Andrew PICKLES, Auteur ; Tom LOUCAS, Auteur ; Emily SIMONOFF, Auteur ; Peter SULLIVAN, Auteur ; Gillian BAIRD, Auteur . - p.305-313. Langues : Anglais (eng) in Autism Research > 7-3 (June 2014) . - p.305-313 Mots-clés : autism  autism spectrum disorders  gut permeability  lactulose/mannitol ratio Index. décimale : PER Périodiques Résumé : Objective To test whether gut permeability is increased in autism spectrum disorders (ASD) by evaluating gut permeability in a population-derived cohort of children with ASD compared with age- and intelligence quotient-matched controls without ASD but with special educational needs (SEN). Patients and Methods One hundred thirty-three children aged 10–14 years, 103 with ASD and 30 with SEN, were given an oral test dose of mannitol and lactulose and urine collected for 6 hr. Gut permeability was assessed by measuring the urine lactulose/mannitol (L/M) recovery ratio by electrospray mass spectrometry-mass spectrometry. The ASD group was subcategorized for comparison into those without (n = 83) and with (n = 20) regression. Results There was no significant difference in L/M recovery ratio (mean (95% confidence interval)) between the groups with ASD: 0.015 (0.013–0.018), and SEN: 0.014 (0.009–0.019), nor in lactulose, mannitol, or creatinine recovery. No significant differences were observed in any parameter for the regressed versus non-regressed ASD groups. Results were consistent with previously published normal ranges. Eleven children (9/103 = 8.7% ASD and 2/30 = 6.7% SEN) had L/M recovery ratio  0.03 (the accepted normal range cut-off), of whom two (one ASD and one SEN) had more definitely pathological L/M recovery ratios  0.04. Conclusion There is no statistically significant group difference in small intestine permeability in a population cohort-derived group of children with ASD compared with a control group with SEN. Of the two children (one ASD and one SEN) with an L/M recovery ratio of  0.04, one had undiagnosed asymptomatic celiac disease (ASD) and the other (SEN) past extensive surgery for gastroschisis. Autism Res 2014, 7: 305–313. © 2013 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1350 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=235

Loss of language in early development of autism and specific language impairment / Andrew PICKLES in Journal of Child Psychology and Psychiatry, 50-7 (July 2009)  

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Parent-Reported Gastro-intestinal Symptoms in Children with Autism Spectrum Disorders / Susie CHANDLER in Journal of Autism and Developmental Disorders, 43-12 (December 2013)  

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Regression, Developmental Trajectory and Associated Problems in Disorders in the Autism Spectrum: The SNAP Study / Gillian BAIRD in Journal of Autism and Developmental Disorders, 38-10 (November 2008)  

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The experience of friendship, victimization and bullying in children with an autism spectrum disorder: Associations with child characteristics and school placement / Emma ROWLEY in Research in Autism Spectrum Disorders, 6-3 (July-September 2012)  

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Using music to assist language learning in autistic children with minimal verbal language: The MAP feasibility RCT / Tim I. WILLIAMS in Autism, 28-10 (October 2024)  

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