Deconstructing the PDD clinical phenotype: internal validity of the DSM-IV / Luc LECAVALIER in Journal of Child Psychology and Psychiatry, 50-10 (October 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-10 (October 2009) . - p.1246-1254 Titre : Deconstructing the PDD clinical phenotype: internal validity of the DSM-IV Type de document : Texte imprimé et/ou numérique Auteurs : Luc LECAVALIER, Auteur ; Kenneth D. GADOW, Auteur ; Carla DEVINCENT, Auteur ; Michael C. EDWARDS, Auteur ; Carrie HOUTS, Auteur Année de publication : 2009 Article en page(s) : p.1246-1254 Langues : Anglais (eng) Mots-clés : Validity autism pervasive-developmental-disorder psychiatric-disorder nosology factor-analysis Index. décimale : PER Périodiques Résumé : Background: Empirical studies of the structure of autism symptoms have challenged the three-domain model of impairment currently characterizing pervasive developmental disorders (PDD). The objective of this study was to assess the internal validity of the DSM as a conceptual model for describing PDD, while paying particular attention to certain subject characteristics. Methods: Parents and teachers completed a DSM-IV-referenced rating scale for 3- to 12-year-old clinic referrals with a PDD (n = 730). Ratings were submitted to confirmatory factor analysis and different models were assessed for fit. Results: Measures of fit indicated that the three-factor solution based on the DSM was superior to other models. Most indices of fit were acceptable, but showed room for improvement. Fit indices varied according to the rater (parent or teacher), child's age (preschool versus school aged), PDD subtype (autism, Asperger's, pervasive developmental disorder not otherwise specified (PDDNOS)), and IQ. Conclusions: More research needs to be done before discarding current classification systems. Subject characteristics, modality of assessment, and procedural variations in statistical analyses impact conclusions about the structure of PDD symptoms. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2009.02104.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=838 [article] Deconstructing the PDD clinical phenotype: internal validity of the DSM-IV [Texte imprimé et/ou numérique] / Luc LECAVALIER, Auteur ; Kenneth D. GADOW, Auteur ; Carla DEVINCENT, Auteur ; Michael C. EDWARDS, Auteur ; Carrie HOUTS, Auteur . - 2009 . - p.1246-1254. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-10 (October 2009) . - p.1246-1254 Mots-clés : Validity autism pervasive-developmental-disorder psychiatric-disorder nosology factor-analysis Index. décimale : PER Périodiques Résumé : Background: Empirical studies of the structure of autism symptoms have challenged the three-domain model of impairment currently characterizing pervasive developmental disorders (PDD). The objective of this study was to assess the internal validity of the DSM as a conceptual model for describing PDD, while paying particular attention to certain subject characteristics. Methods: Parents and teachers completed a DSM-IV-referenced rating scale for 3- to 12-year-old clinic referrals with a PDD (n = 730). Ratings were submitted to confirmatory factor analysis and different models were assessed for fit. Results: Measures of fit indicated that the three-factor solution based on the DSM was superior to other models. Most indices of fit were acceptable, but showed room for improvement. Fit indices varied according to the rater (parent or teacher), child's age (preschool versus school aged), PDD subtype (autism, Asperger's, pervasive developmental disorder not otherwise specified (PDDNOS)), and IQ. Conclusions: More research needs to be done before discarding current classification systems. Subject characteristics, modality of assessment, and procedural variations in statistical analyses impact conclusions about the structure of PDD symptoms. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2009.02104.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=838

MAOA-uVNTR and early physical discipline interact to influence delinquent behavior / Michael C. EDWARDS in Journal of Child Psychology and Psychiatry, 51-6 (June 2010)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 51-6 (June 2010) . - p.679-687 Titre : MAOA-uVNTR and early physical discipline interact to influence delinquent behavior Type de document : Texte imprimé et/ou numérique Auteurs : Michael C. EDWARDS, Auteur ; Jennifer E. LANSFORD, Auteur ; Gregory S. PETTIT, Auteur ; Kenneth A. DODGE, Auteur ; John E. BATES, Auteur ; Shawn J. LATENDRESSE, Auteur ; Danielle M. DICK, Auteur ; John P. BUDDE, Auteur ; Alison M. GOATE, Auteur Année de publication : 2010 Article en page(s) : p.679-687 Langues : Anglais (eng) Mots-clés : Externalizing-behavior genetics physical-discipline maltreatment Index. décimale : PER Périodiques Résumé : Background: A functional polymorphism in the promoter region of the monoamine oxidizing gene monoamine oxidase A (MAOA) has been associated with behavioral sensitivity to adverse environmental conditions in multiple studies (e.g., Caspi et al. 2002; Kim-Cohen et al., 2006). The present study investigates the effects of genotype and early physical discipline on externalizing behavior. We expand on the current literature in our assessment of externalizing, incorporating information across multiple reporters and over a broad developmental time period, and in our understanding of environmental risk. Method: This study uses data from the Child Development Project, an ongoing longitudinal study following a community sample of children beginning at age 5. Physical discipline before age 6 was quantified using a subset of questions from the Conflict Tactics Scale (Straus, 1979). Externalizing behavior was assessed in the male, European-American sub-sample (N = 250) by parent, teacher, and self-report using Achenbach's Child Behavior Checklist, Teacher Report Form, and Youth Self-Report (Achenbach, 1991), at 17 time points from ages 6 to 22. Regression analyses tested the influence of genotype, physical discipline, and their interaction on externalizing behavior, and its subscales, delinquency and aggression. Results: We found a significant interaction effect between genotype and physical discipline on levels of delinquent behavior. Similar trends were observed for aggression and overall externalizing behavior, although these did not reach statistical significance. Main effects of physical discipline held for all outcome variables, and no main effects held for genotype. Conclusion: The adverse consequences of physical discipline on forms of externalizing behavior are exacerbated by an underlying biological risk conferred by MAOA genotype. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2009.02196.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=101 [article] MAOA-uVNTR and early physical discipline interact to influence delinquent behavior [Texte imprimé et/ou numérique] / Michael C. EDWARDS, Auteur ; Jennifer E. LANSFORD, Auteur ; Gregory S. PETTIT, Auteur ; Kenneth A. DODGE, Auteur ; John E. BATES, Auteur ; Shawn J. LATENDRESSE, Auteur ; Danielle M. DICK, Auteur ; John P. BUDDE, Auteur ; Alison M. GOATE, Auteur . - 2010 . - p.679-687. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 51-6 (June 2010) . - p.679-687 Mots-clés : Externalizing-behavior genetics physical-discipline maltreatment Index. décimale : PER Périodiques Résumé : Background: A functional polymorphism in the promoter region of the monoamine oxidizing gene monoamine oxidase A (MAOA) has been associated with behavioral sensitivity to adverse environmental conditions in multiple studies (e.g., Caspi et al. 2002; Kim-Cohen et al., 2006). The present study investigates the effects of genotype and early physical discipline on externalizing behavior. We expand on the current literature in our assessment of externalizing, incorporating information across multiple reporters and over a broad developmental time period, and in our understanding of environmental risk. Method: This study uses data from the Child Development Project, an ongoing longitudinal study following a community sample of children beginning at age 5. Physical discipline before age 6 was quantified using a subset of questions from the Conflict Tactics Scale (Straus, 1979). Externalizing behavior was assessed in the male, European-American sub-sample (N = 250) by parent, teacher, and self-report using Achenbach's Child Behavior Checklist, Teacher Report Form, and Youth Self-Report (Achenbach, 1991), at 17 time points from ages 6 to 22. Regression analyses tested the influence of genotype, physical discipline, and their interaction on externalizing behavior, and its subscales, delinquency and aggression. Results: We found a significant interaction effect between genotype and physical discipline on levels of delinquent behavior. Similar trends were observed for aggression and overall externalizing behavior, although these did not reach statistical significance. Main effects of physical discipline held for all outcome variables, and no main effects held for genotype. Conclusion: The adverse consequences of physical discipline on forms of externalizing behavior are exacerbated by an underlying biological risk conferred by MAOA genotype. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2009.02196.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=101

The Structure of Autism Symptoms as Measured by the Autism Diagnostic Observation Schedule / Megan NORRIS in Journal of Autism and Developmental Disorders, 42-6 (June 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-6 (June 2012) . - p.1075-1086 Titre : The Structure of Autism Symptoms as Measured by the Autism Diagnostic Observation Schedule Type de document : Texte imprimé et/ou numérique Auteurs : Megan NORRIS, Auteur ; Luc LECAVALIER, Auteur ; Michael C. EDWARDS, Auteur Année de publication : 2012 Article en page(s) : p.1075-1086 Langues : Anglais (eng) Mots-clés : Confirmatory factor analysis  Autism  Autism Spectrum Disorders  Pervasive developmental disorders  Symptoms Index. décimale : PER Périodiques Résumé : The current study tested several competing models of the autism phenotype using data from modules 1 and 3 of the ADOS. Participants included individuals with ASDs aged 3–18 years (N = 1,409) from the AGRE database. Confirmatory factor analyses were performed on total samples and subsamples based on age and level of functioning. Three primary models were tested, including a one-factor model, the DSM-IV model, and the anticipated DSM-V model. Results indicated all models fit similarly. Module 1 ratings yielded better indices of fit across all models and higher inter-factor correlations than Model 3. Model fits were impacted by age and level of functioning. The lack of differentiation between models suggests that the structure of ASD symptoms is complex to measure statistically. En ligne : http://dx.doi.org/10.1007/s10803-011-1348-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=156 [article] The Structure of Autism Symptoms as Measured by the Autism Diagnostic Observation Schedule [Texte imprimé et/ou numérique] / Megan NORRIS, Auteur ; Luc LECAVALIER, Auteur ; Michael C. EDWARDS, Auteur . - 2012 . - p.1075-1086. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-6 (June 2012) . - p.1075-1086 Mots-clés : Confirmatory factor analysis  Autism  Autism Spectrum Disorders  Pervasive developmental disorders  Symptoms Index. décimale : PER Périodiques Résumé : The current study tested several competing models of the autism phenotype using data from modules 1 and 3 of the ADOS. Participants included individuals with ASDs aged 3–18 years (N = 1,409) from the AGRE database. Confirmatory factor analyses were performed on total samples and subsamples based on age and level of functioning. Three primary models were tested, including a one-factor model, the DSM-IV model, and the anticipated DSM-V model. Results indicated all models fit similarly. Module 1 ratings yielded better indices of fit across all models and higher inter-factor correlations than Model 3. Model fits were impacted by age and level of functioning. The lack of differentiation between models suggests that the structure of ASD symptoms is complex to measure statistically. En ligne : http://dx.doi.org/10.1007/s10803-011-1348-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=156

Toward better outcome measurement for insomnia in children with autism spectrum disorder / Luc LECAVALIER ; Michael C. EDWARDS ; Megan L. WENZELL ; Leah M. BARTO ; Arielle MULLIGAN ; Auscia T. WILLIAMS ; Opal OUSLEY ; Cynthia B. SINHA ; Christopher A. TAYLOR ; Soo Youn KIM ; Laura M. JOHNSON ; Scott E. GILLESPIE ; Cynthia R. JOHNSON in Autism, 28-12 (December 2024)  

Public ISBD [article]  inAutism > 28-12 (December 2024) . - p.3131-3142 Titre : Toward better outcome measurement for insomnia in children with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Luc LECAVALIER, Auteur ; Michael C. EDWARDS, Auteur ; Megan L. WENZELL, Auteur ; Leah M. BARTO, Auteur ; Arielle MULLIGAN, Auteur ; Auscia T. WILLIAMS, Auteur ; Opal OUSLEY, Auteur ; Cynthia B. SINHA, Auteur ; Christopher A. TAYLOR, Auteur ; Soo Youn KIM, Auteur ; Laura M. JOHNSON, Auteur ; Scott E. GILLESPIE, Auteur ; Cynthia R. JOHNSON, Auteur Article en page(s) : p.3131-3142 Langues : Anglais (eng) Mots-clés : autism  children  insomnia  outcome measure Index. décimale : PER Périodiques Résumé : This report presents a new parent-rated outcome measure of insomnia for children with autism spectrum disorder. Parents of 1185 children with autism spectrum disorder (aged 3-12; 80.3% male) completed the first draft of the measure online. Factor and item response theory analyses reduced the set of 40 items to the final 21-item Pediatric Insomnia Autism Rating Scale. In this online sample, Pediatric Insomnia Autism Rating Scale mean was 21.8?+?15.0 (range 0-63; coefficient alpha = 0.94). Item response theory results indicated excellent reliability across a range of scores. Next, we conducted a telehealth assessment of 134 children with autism spectrum disorder (aged 3-12; 73% male). In this clinical sample, Pediatric Insomnia Autism Rating Scale mean was 28.9?+?14.62 (range 0-61; coefficient alpha = 0.93). Pearson correlations of Pediatric Insomnia Autism Rating Scale with the PROMIS Sleep Disturbance and the modified Children?s Sleep Habits Questionnaire was 0.74 for each. This was significantly higher than correlations of parent-rated disruptive behavior, hyperactivity, repetitive behavior, and anxiety measures (range 0.29-0.59)-supporting convergent and divergent validity. Parents of 63 children completed the Pediatric Insomnia Autism Rating Scale three times over 4?weeks. Intraclass correlation was excellent (0.88) over three time points. Pediatric Insomnia Autism Rating Scale is a valid dimensional measure of insomnia in autistic children that produces reliable scores. Lay Abstract Insomnia, trouble falling asleep or staying asleep, is common in autistic children. In a previous report, we described the results of focus groups with parents of autistic children toward the development of the Pediatric Autism Insomnia Rating Scale. In this article, we report on the steps taken to complete the Pediatric Autism Insomnia Rating Scale. With help from the Simons Foundation registry, we collected information from parents on 1185 children with autism spectrum disorder to test the new measure. These results were evaluated using standard statistical methods such as factor analysis. To confirm the validity of the new measure, we enrolled a separate sample of 134 autistic children for a detailed assessment by video conference. This step showed that the Pediatric Autism Insomnia Rating Scale is clearly measuring symptoms of insomnia in children with autism spectrum disorder and not related problems such as hyperactivity, repetitive behavior, or anxiety. We also showed that the total score on the Pediatric Autism Insomnia Rating Scale is stable when repeated over a brief period of time. This is important because a measure that is not stable over a brief period of time would not be suitable as an outcome measure. In summary, the Pediatric Autism Insomnia Rating Scale is a brief and valid measure of insomnia in children with autism spectrum disorder that provides reliable scores. En ligne : https://dx.doi.org/10.1177/13623613241255814 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=543 [article] Toward better outcome measurement for insomnia in children with autism spectrum disorder [Texte imprimé et/ou numérique] / Luc LECAVALIER, Auteur ; Michael C. EDWARDS, Auteur ; Megan L. WENZELL, Auteur ; Leah M. BARTO, Auteur ; Arielle MULLIGAN, Auteur ; Auscia T. WILLIAMS, Auteur ; Opal OUSLEY, Auteur ; Cynthia B. SINHA, Auteur ; Christopher A. TAYLOR, Auteur ; Soo Youn KIM, Auteur ; Laura M. JOHNSON, Auteur ; Scott E. GILLESPIE, Auteur ; Cynthia R. JOHNSON, Auteur . - p.3131-3142. Langues : Anglais (eng) in Autism > 28-12 (December 2024) . - p.3131-3142 Mots-clés : autism  children  insomnia  outcome measure Index. décimale : PER Périodiques Résumé : This report presents a new parent-rated outcome measure of insomnia for children with autism spectrum disorder. Parents of 1185 children with autism spectrum disorder (aged 3-12; 80.3% male) completed the first draft of the measure online. Factor and item response theory analyses reduced the set of 40 items to the final 21-item Pediatric Insomnia Autism Rating Scale. In this online sample, Pediatric Insomnia Autism Rating Scale mean was 21.8?+?15.0 (range 0-63; coefficient alpha = 0.94). Item response theory results indicated excellent reliability across a range of scores. Next, we conducted a telehealth assessment of 134 children with autism spectrum disorder (aged 3-12; 73% male). In this clinical sample, Pediatric Insomnia Autism Rating Scale mean was 28.9?+?14.62 (range 0-61; coefficient alpha = 0.93). Pearson correlations of Pediatric Insomnia Autism Rating Scale with the PROMIS Sleep Disturbance and the modified Children?s Sleep Habits Questionnaire was 0.74 for each. This was significantly higher than correlations of parent-rated disruptive behavior, hyperactivity, repetitive behavior, and anxiety measures (range 0.29-0.59)-supporting convergent and divergent validity. Parents of 63 children completed the Pediatric Insomnia Autism Rating Scale three times over 4?weeks. Intraclass correlation was excellent (0.88) over three time points. Pediatric Insomnia Autism Rating Scale is a valid dimensional measure of insomnia in autistic children that produces reliable scores. Lay Abstract Insomnia, trouble falling asleep or staying asleep, is common in autistic children. In a previous report, we described the results of focus groups with parents of autistic children toward the development of the Pediatric Autism Insomnia Rating Scale. In this article, we report on the steps taken to complete the Pediatric Autism Insomnia Rating Scale. With help from the Simons Foundation registry, we collected information from parents on 1185 children with autism spectrum disorder to test the new measure. These results were evaluated using standard statistical methods such as factor analysis. To confirm the validity of the new measure, we enrolled a separate sample of 134 autistic children for a detailed assessment by video conference. This step showed that the Pediatric Autism Insomnia Rating Scale is clearly measuring symptoms of insomnia in children with autism spectrum disorder and not related problems such as hyperactivity, repetitive behavior, or anxiety. We also showed that the total score on the Pediatric Autism Insomnia Rating Scale is stable when repeated over a brief period of time. This is important because a measure that is not stable over a brief period of time would not be suitable as an outcome measure. In summary, the Pediatric Autism Insomnia Rating Scale is a brief and valid measure of insomnia in children with autism spectrum disorder that provides reliable scores. En ligne : https://dx.doi.org/10.1177/13623613241255814 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=543

Validation of DSM-IV Model of Psychiatric Syndromes in Children with Autism Spectrum Disorders / Luc LECAVALIER in Journal of Autism and Developmental Disorders, 39-2 (February 2009)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 39-2 (February 2009) . - p.278-289 Titre : Validation of DSM-IV Model of Psychiatric Syndromes in Children with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Luc LECAVALIER, Auteur ; Kenneth D. GADOW, Auteur ; Carla DEVINCENT, Auteur ; Michael C. EDWARDS, Auteur Année de publication : 2009 Article en page(s) : p.278-289 Langues : Anglais (eng) Mots-clés : Validity Autism Pervasive-developmental-disorder Psychiatric-disorder Nosology Factor-analysis Index. décimale : PER Périodiques Résumé : The objective of this study was to assess the internal construct validity of the DSM-IV as a conceptual model for characterizing behavioral syndromes in children with ASD. Parent and teachers completed the Child Symptom Inventory-4, a DSM-IV-referenced rating scale, for 6-to-12 year old clinic referrals with an ASD (N = 498). Ratings were submitted to confirmatory factor analysis and models were assessed for fit. Results were also compared to those obtained for a sample of non-ASD psychiatric outpatient school-age children. Fit indices ranged from acceptable to good for the ASD samples and compared well to those obtained in typically developing children. Findings lend support to the notion that DSM-IV syndromes may be an appropriate conceptual model for characterizing psychopathology in ASD. En ligne : http://dx.doi.org/10.1007/s10803-008-0622-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=684 [article] Validation of DSM-IV Model of Psychiatric Syndromes in Children with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Luc LECAVALIER, Auteur ; Kenneth D. GADOW, Auteur ; Carla DEVINCENT, Auteur ; Michael C. EDWARDS, Auteur . - 2009 . - p.278-289. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 39-2 (February 2009) . - p.278-289 Mots-clés : Validity Autism Pervasive-developmental-disorder Psychiatric-disorder Nosology Factor-analysis Index. décimale : PER Périodiques Résumé : The objective of this study was to assess the internal construct validity of the DSM-IV as a conceptual model for characterizing behavioral syndromes in children with ASD. Parent and teachers completed the Child Symptom Inventory-4, a DSM-IV-referenced rating scale, for 6-to-12 year old clinic referrals with an ASD (N = 498). Ratings were submitted to confirmatory factor analysis and models were assessed for fit. Results were also compared to those obtained for a sample of non-ASD psychiatric outpatient school-age children. Fit indices ranged from acceptable to good for the ASD samples and compared well to those obtained in typically developing children. Findings lend support to the notion that DSM-IV syndromes may be an appropriate conceptual model for characterizing psychopathology in ASD. En ligne : http://dx.doi.org/10.1007/s10803-008-0622-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=684

Validity of DSM-IV syndromes in preschoolers with autism spectrum disorders / Luc LECAVALIER in Autism, 15-5 (September 2011)  

Permalink

---

1 (1 - 6 / 6)