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Auteur Henrik ANCKARSATER |
Documents disponibles écrits par cet auteur (13)



Adults with Asperger syndrome with and without a cognitive profile associated with “non-verbal learning disability.” A brief report / Agneta NYDEN in Research in Autism Spectrum Disorders, 4-4 (October-December 2010)
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[article]
Titre : Adults with Asperger syndrome with and without a cognitive profile associated with “non-verbal learning disability.” A brief report Type de document : Texte imprimé et/ou numérique Auteurs : Agneta NYDEN, Auteur ; Maria RASTAM, Auteur ; Annika DAHLGREN SANDBERG, Auteur ; Henrik ANCKARSATER, Auteur ; Lena NIKLASSON, Auteur ; Ola STAHLBERG, Auteur ; Elisabeth WENTZ, Auteur Année de publication : 2010 Article en page(s) : p.612-618 Langues : Anglais (eng) Mots-clés : Adults Asperger-syndrome Neuropsychology Non-verbal-learning-disability Index. décimale : PER Périodiques Résumé : Asperger syndrome (AS) and non-verbal learning disability (NLD) are both characterized by impairments in motor coordination, visuo-perceptual abilities, pragmatics and comprehension of language and social understanding. NLD is also defined as a learning disorder affecting functions in the right cerebral hemisphere. The present study investigates if individuals with AS and a cognitive profile consistent with NLD (i.e. verbal IQ > performance IQ) would also have other problems inherent in NLD, visual memory and attention, reading/writing ability and arithmetic in the presence of preserved verbal memory and attention. Forty-four individuals with AS were assessed with a battery of neuropsychological tests. Reading/writing and arithmetic abilities were investigated. Education and global social adaptive levels were studied. Very few AS participants, even though with NLD cognitive profile showed problems with any of the neurocognitive abilities or academic achievements. However, all had poor global social adaptive functioning and few had paid employment, regardless of their cognitive profile. The present study suggests that AS and NLD are two different conditions even though some individuals in both groups have the verbal IQ > performance IQ profile that has been proposed to be typical of both AS and NLD. En ligne : http://dx.doi.org/10.1016/j.rasd.2009.12.004 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=102
in Research in Autism Spectrum Disorders > 4-4 (October-December 2010) . - p.612-618[article] Adults with Asperger syndrome with and without a cognitive profile associated with “non-verbal learning disability.” A brief report [Texte imprimé et/ou numérique] / Agneta NYDEN, Auteur ; Maria RASTAM, Auteur ; Annika DAHLGREN SANDBERG, Auteur ; Henrik ANCKARSATER, Auteur ; Lena NIKLASSON, Auteur ; Ola STAHLBERG, Auteur ; Elisabeth WENTZ, Auteur . - 2010 . - p.612-618.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 4-4 (October-December 2010) . - p.612-618
Mots-clés : Adults Asperger-syndrome Neuropsychology Non-verbal-learning-disability Index. décimale : PER Périodiques Résumé : Asperger syndrome (AS) and non-verbal learning disability (NLD) are both characterized by impairments in motor coordination, visuo-perceptual abilities, pragmatics and comprehension of language and social understanding. NLD is also defined as a learning disorder affecting functions in the right cerebral hemisphere. The present study investigates if individuals with AS and a cognitive profile consistent with NLD (i.e. verbal IQ > performance IQ) would also have other problems inherent in NLD, visual memory and attention, reading/writing ability and arithmetic in the presence of preserved verbal memory and attention. Forty-four individuals with AS were assessed with a battery of neuropsychological tests. Reading/writing and arithmetic abilities were investigated. Education and global social adaptive levels were studied. Very few AS participants, even though with NLD cognitive profile showed problems with any of the neurocognitive abilities or academic achievements. However, all had poor global social adaptive functioning and few had paid employment, regardless of their cognitive profile. The present study suggests that AS and NLD are two different conditions even though some individuals in both groups have the verbal IQ > performance IQ profile that has been proposed to be typical of both AS and NLD. En ligne : http://dx.doi.org/10.1016/j.rasd.2009.12.004 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=102 Association study between autistic-like traits and polymorphisms in the autism candidate regions RELN, CNTNAP2, SHANK3, and CDH9/10 / Lina JONSSON in Molecular Autism, (December 2014)
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Titre : Association study between autistic-like traits and polymorphisms in the autism candidate regions RELN, CNTNAP2, SHANK3, and CDH9/10 Type de document : Texte imprimé et/ou numérique Auteurs : Lina JONSSON, Auteur ; Anna ZETTERGREN, Auteur ; Erik PETTERSSON, Auteur ; Daniel HOVEY, Auteur ; Henrik ANCKARSATER, Auteur ; Lars WESTBERG, Auteur ; Paul LICHTENSTEIN, Auteur ; Sebastian LUNDSTROM, Auteur ; Jonas MELKE, Auteur Article en page(s) : p.1-9 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autistic-like traits (ALTs) are continuously distributed in the general population, with the autism spectrum disorder (ASD) at the upper extreme end. A genetic overlap has been shown between ALTs and ASD, indicating that common variation in ASD candidate genes may also influence ALTs. In our study, we have investigated the SNP rs4307059 that has been associated with both ALTs and ASD. In addition, we genotyped polymorphisms in a selection of genes involved in synaptic functioning, that is, SHANK3, RELN, and CNTNAP2, which repeatedly have been associated with ASD. The possible associations of these polymorphisms with ALTs, as well as genetic factors for neurodevelopmental problems (NDPs), were investigated in a large cohort from the general population: The Child and Adolescent Twin Study in Sweden. For analyses of ALTs and NDPs, 12,319 subjects (including 2,268 monozygotic (MZ) and 3,805 dizygotic (DZ) twin pairs) and 8,671 subjects (including 2,243 MZ and 2,044 DZ twin pairs), respectively, were included in the analyses. En ligne : http://dx.doi.org/10.1186/2040-2392-5-55 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277
in Molecular Autism > (December 2014) . - p.1-9[article] Association study between autistic-like traits and polymorphisms in the autism candidate regions RELN, CNTNAP2, SHANK3, and CDH9/10 [Texte imprimé et/ou numérique] / Lina JONSSON, Auteur ; Anna ZETTERGREN, Auteur ; Erik PETTERSSON, Auteur ; Daniel HOVEY, Auteur ; Henrik ANCKARSATER, Auteur ; Lars WESTBERG, Auteur ; Paul LICHTENSTEIN, Auteur ; Sebastian LUNDSTROM, Auteur ; Jonas MELKE, Auteur . - p.1-9.
Langues : Anglais (eng)
in Molecular Autism > (December 2014) . - p.1-9
Index. décimale : PER Périodiques Résumé : Autistic-like traits (ALTs) are continuously distributed in the general population, with the autism spectrum disorder (ASD) at the upper extreme end. A genetic overlap has been shown between ALTs and ASD, indicating that common variation in ASD candidate genes may also influence ALTs. In our study, we have investigated the SNP rs4307059 that has been associated with both ALTs and ASD. In addition, we genotyped polymorphisms in a selection of genes involved in synaptic functioning, that is, SHANK3, RELN, and CNTNAP2, which repeatedly have been associated with ASD. The possible associations of these polymorphisms with ALTs, as well as genetic factors for neurodevelopmental problems (NDPs), were investigated in a large cohort from the general population: The Child and Adolescent Twin Study in Sweden. For analyses of ALTs and NDPs, 12,319 subjects (including 2,268 monozygotic (MZ) and 3,805 dizygotic (DZ) twin pairs) and 8,671 subjects (including 2,243 MZ and 2,044 DZ twin pairs), respectively, were included in the analyses. En ligne : http://dx.doi.org/10.1186/2040-2392-5-55 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 Associations between conduct problems in childhood and adverse outcomes in emerging adulthood: a longitudinal Swedish nationwide twin cohort / Paul LICHTENSTEIN in Journal of Child Psychology and Psychiatry, 61-7 (July 2020)
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Titre : Associations between conduct problems in childhood and adverse outcomes in emerging adulthood: a longitudinal Swedish nationwide twin cohort Type de document : Texte imprimé et/ou numérique Auteurs : Paul LICHTENSTEIN, Auteur ; Martin CEDERLÖF, Auteur ; Sebastian LUNDSTROM, Auteur ; Brian M. D'ONOFRIO, Auteur ; Henrik ANCKARSATER, Auteur ; Henrik LARSSON, Auteur ; Erik PETTERSSON, Auteur Article en page(s) : p.798-806 Langues : Anglais (eng) Mots-clés : Twins comorbidity conduct disorder externalizing disorder internalizing disorder Index. décimale : PER Périodiques Résumé : BACKGROUND: We examined whether childhood conduct problems predicted a wide range of adverse outcomes in emerging adulthood and whether the association with internalizing problems remained after adjusting for general comorbidity and externalizing problems. METHODS: Participants were 18,649 twins from the Child and Adolescent Twin Study in Sweden. At age 9/12, parents rated their children on eight conduct problems. Adverse outcomes were retrieved from national registers in emerging adulthood (median follow-up time = 9.2 years), including diagnoses of six psychiatric disorders, prescriptions of antidepressants, suicide attempts, criminality, high school ineligibility, and social welfare recipiency. We estimated risk for the separate outcomes and examined if conduct problems predicted an internalizing factor above and beyond a general comorbidity and an externalizing factor. We used twin analyses to estimate genetic and environmental contributions to these associations. RESULTS: On the average, each additional conduct symptom in childhood was associated with a 32% increased risk of the adverse outcomes in emerging adulthood (mean hazard ratio = 1.32; range = 1.16, 1.56). A latent childhood conduct problems factor predicted the internalizing factor in emerging adulthood (?(boys) = .24, standard error, SE = 0.03; ?(girls) = .17, SE = 0.03), above and beyond its association with the externalizing (?(boys) = 0.21, SE = 0.04; ?(girls) = 0.17, SE = 0.05) and general factors (?(boys) = 0.45, SE = 0.03; ?(girls) = 0.34, SE = 0.04). These associations were differentially influenced by genetic and environmental factors. CONCLUSIONS: It is important to monitor boys and girls with conduct problems not only for future externalizing problems, but also for future internalizing problems. Prevention of specific outcomes, however, might require interventions at different levels. En ligne : http://dx.doi.org/10.1111/jcpp.13169 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429
in Journal of Child Psychology and Psychiatry > 61-7 (July 2020) . - p.798-806[article] Associations between conduct problems in childhood and adverse outcomes in emerging adulthood: a longitudinal Swedish nationwide twin cohort [Texte imprimé et/ou numérique] / Paul LICHTENSTEIN, Auteur ; Martin CEDERLÖF, Auteur ; Sebastian LUNDSTROM, Auteur ; Brian M. D'ONOFRIO, Auteur ; Henrik ANCKARSATER, Auteur ; Henrik LARSSON, Auteur ; Erik PETTERSSON, Auteur . - p.798-806.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-7 (July 2020) . - p.798-806
Mots-clés : Twins comorbidity conduct disorder externalizing disorder internalizing disorder Index. décimale : PER Périodiques Résumé : BACKGROUND: We examined whether childhood conduct problems predicted a wide range of adverse outcomes in emerging adulthood and whether the association with internalizing problems remained after adjusting for general comorbidity and externalizing problems. METHODS: Participants were 18,649 twins from the Child and Adolescent Twin Study in Sweden. At age 9/12, parents rated their children on eight conduct problems. Adverse outcomes were retrieved from national registers in emerging adulthood (median follow-up time = 9.2 years), including diagnoses of six psychiatric disorders, prescriptions of antidepressants, suicide attempts, criminality, high school ineligibility, and social welfare recipiency. We estimated risk for the separate outcomes and examined if conduct problems predicted an internalizing factor above and beyond a general comorbidity and an externalizing factor. We used twin analyses to estimate genetic and environmental contributions to these associations. RESULTS: On the average, each additional conduct symptom in childhood was associated with a 32% increased risk of the adverse outcomes in emerging adulthood (mean hazard ratio = 1.32; range = 1.16, 1.56). A latent childhood conduct problems factor predicted the internalizing factor in emerging adulthood (?(boys) = .24, standard error, SE = 0.03; ?(girls) = .17, SE = 0.03), above and beyond its association with the externalizing (?(boys) = 0.21, SE = 0.04; ?(girls) = 0.17, SE = 0.05) and general factors (?(boys) = 0.45, SE = 0.03; ?(girls) = 0.34, SE = 0.04). These associations were differentially influenced by genetic and environmental factors. CONCLUSIONS: It is important to monitor boys and girls with conduct problems not only for future externalizing problems, but also for future internalizing problems. Prevention of specific outcomes, however, might require interventions at different levels. En ligne : http://dx.doi.org/10.1111/jcpp.13169 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429 Autism spectrum disorders and coexisting disorders in a nationwide Swedish twin study / Sebastian LUNDSTROM in Journal of Child Psychology and Psychiatry, 56-6 (June 2015)
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Titre : Autism spectrum disorders and coexisting disorders in a nationwide Swedish twin study Type de document : Texte imprimé et/ou numérique Auteurs : Sebastian LUNDSTROM, Auteur ; Abraham REICHENBERG, Auteur ; Jonas MELKE, Auteur ; Maria RASTAM, Auteur ; Nora KEREKES, Auteur ; Paul LICHTENSTEIN, Auteur ; Christopher GILLBERG, Auteur ; Henrik ANCKARSATER, Auteur Article en page(s) : p.702-710 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders comorbidity genetics twins Index. décimale : PER Périodiques Résumé : Background Evidence from twin and molecular genetic studies is accumulating that Autism Spectrum Disorder (ASD) shares substantial etiological factors with other disorders. This is mirrored in clinical practice where ASD without coexisting disorders is rare. The present study aims to examine the range of coexisting disorders in ASD in a genetically informative cohort. Methods Parents of all Swedish 9-year-old twins born between 1992 and 2001 (n = 19,130) underwent a telephone interview designed to screen for child psychiatric disorders, including ASD. To ensure full coverage of child psychiatric disorders, data were also retrieved from population-based health registers. We investigated the coexistence of eight psychiatric disorders known to coexist with ASDs in probands and their co-twins. Results Half of the individuals with ASDs (50.3%) had four or more coexisting disorders and only 4% did not have any concomitant disorder. The ‘healthy co-twin’ in ASD discordant monozygotic twin pairs was very often (79% of boys and 50% of girls) affected by at least one non-ASD disorder. The corresponding figures for ASD discordant dizygotic twin pairs were significantly lower (46% of males and 30% of females). Conclusions Detailed phenotypic descriptions including symptoms of problems associated with a wide range of child psychiatric disorders may aid in unraveling the genetic architecture of ASD and should guide the development of intervention strategies addressing each problem type specifically. En ligne : http://dx.doi.org/10.1111/jcpp.12329 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260
in Journal of Child Psychology and Psychiatry > 56-6 (June 2015) . - p.702-710[article] Autism spectrum disorders and coexisting disorders in a nationwide Swedish twin study [Texte imprimé et/ou numérique] / Sebastian LUNDSTROM, Auteur ; Abraham REICHENBERG, Auteur ; Jonas MELKE, Auteur ; Maria RASTAM, Auteur ; Nora KEREKES, Auteur ; Paul LICHTENSTEIN, Auteur ; Christopher GILLBERG, Auteur ; Henrik ANCKARSATER, Auteur . - p.702-710.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 56-6 (June 2015) . - p.702-710
Mots-clés : Autism spectrum disorders comorbidity genetics twins Index. décimale : PER Périodiques Résumé : Background Evidence from twin and molecular genetic studies is accumulating that Autism Spectrum Disorder (ASD) shares substantial etiological factors with other disorders. This is mirrored in clinical practice where ASD without coexisting disorders is rare. The present study aims to examine the range of coexisting disorders in ASD in a genetically informative cohort. Methods Parents of all Swedish 9-year-old twins born between 1992 and 2001 (n = 19,130) underwent a telephone interview designed to screen for child psychiatric disorders, including ASD. To ensure full coverage of child psychiatric disorders, data were also retrieved from population-based health registers. We investigated the coexistence of eight psychiatric disorders known to coexist with ASDs in probands and their co-twins. Results Half of the individuals with ASDs (50.3%) had four or more coexisting disorders and only 4% did not have any concomitant disorder. The ‘healthy co-twin’ in ASD discordant monozygotic twin pairs was very often (79% of boys and 50% of girls) affected by at least one non-ASD disorder. The corresponding figures for ASD discordant dizygotic twin pairs were significantly lower (46% of males and 30% of females). Conclusions Detailed phenotypic descriptions including symptoms of problems associated with a wide range of child psychiatric disorders may aid in unraveling the genetic architecture of ASD and should guide the development of intervention strategies addressing each problem type specifically. En ligne : http://dx.doi.org/10.1111/jcpp.12329 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 Autism Spectrum Disorders and Coexisting Mental Health Problems / Ola STAHLBERG in Key Issues in Mental Health, 180 (2015)
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Titre : Autism Spectrum Disorders and Coexisting Mental Health Problems Type de document : Texte imprimé et/ou numérique Auteurs : Ola STAHLBERG, Auteur ; Thomas NILSSON, Auteur ; Sebastian LUNDSTROM, Auteur ; Henrik ANCKARSATER, Auteur Article en page(s) : p.5-19 Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Résumé : It is a rule rather than an exception that mental disorders occur in complex and manifold forms, and a number of models have been proposed to explain this co-occurrence or co-‘morbidity'. Autism spectrum disorders (ASD, i.e. autistic disorder, Asperger syndrome, and pervasive developmental disorder - not otherwise specified) are no exemption. Here, the literature on ASD co-occurring with developmental disorders (such as ADHD), learning disorders, and problems that typically arise during childhood (e.g. oppositional defiant disorder, conduct disorder), and adulthood (e.g. anxiety, affective/mood disorders, and psychotic disorders), will be reviewed. The patterns of mental disorders co-occurring with ASD could not be summarized into any consistent and easy-to-interpret model of co-morbidity. Thus, research on ASD should consider and not rule out coexisting mental conditions (and include persons with complex problems in studies), clinical assessments, and evaluations. Ignoring the complexity of co-occurring conditions will have detrimental effects in research, counteracting our understanding of the etiology behind ASD and the development of evidence-based, comprehensive treatment strategies. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=271
in Key Issues in Mental Health > 180 (2015) . - p.5-19[article] Autism Spectrum Disorders and Coexisting Mental Health Problems [Texte imprimé et/ou numérique] / Ola STAHLBERG, Auteur ; Thomas NILSSON, Auteur ; Sebastian LUNDSTROM, Auteur ; Henrik ANCKARSATER, Auteur . - p.5-19.
Langues : Anglais (eng)
in Key Issues in Mental Health > 180 (2015) . - p.5-19
Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Résumé : It is a rule rather than an exception that mental disorders occur in complex and manifold forms, and a number of models have been proposed to explain this co-occurrence or co-‘morbidity'. Autism spectrum disorders (ASD, i.e. autistic disorder, Asperger syndrome, and pervasive developmental disorder - not otherwise specified) are no exemption. Here, the literature on ASD co-occurring with developmental disorders (such as ADHD), learning disorders, and problems that typically arise during childhood (e.g. oppositional defiant disorder, conduct disorder), and adulthood (e.g. anxiety, affective/mood disorders, and psychotic disorders), will be reviewed. The patterns of mental disorders co-occurring with ASD could not be summarized into any consistent and easy-to-interpret model of co-morbidity. Thus, research on ASD should consider and not rule out coexisting mental conditions (and include persons with complex problems in studies), clinical assessments, and evaluations. Ignoring the complexity of co-occurring conditions will have detrimental effects in research, counteracting our understanding of the etiology behind ASD and the development of evidence-based, comprehensive treatment strategies. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=271 Birth weight as an independent predictor of ADHD symptoms: a within-twin pair analysis / Erik PETTERSSON in Journal of Child Psychology and Psychiatry, 56-4 (April 2015)
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PermalinkChildhood attention-deficit hyperactivity disorder as an extreme of a continuous trait: a quantitative genetic study of 8,500 twin pairs / Henrik LARSSON in Journal of Child Psychology and Psychiatry, 53-1 (January 2012)
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PermalinkCorrection to: Physical health in children with neurodevelopmental disorders / S. ALABAF in Journal of Autism and Developmental Disorders, 49-1 (January 2019)
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PermalinkDifferent neurodevelopmental symptoms have a common genetic etiology / Erik PETTERSSON in Journal of Child Psychology and Psychiatry, 54-12 (December 2013)
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PermalinkEffects of autism spectrum disorders on outcome in teenage-onset anorexia nervosa evaluated by the Morgan-Russell outcome assessment schedule: a controlled community-based study / Søren NIELSEN in Molecular Autism, (March 2015)
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PermalinkMotor function and perception in children with neuropsychiatric and conduct problems: results from a population based twin study / P. GUSTAFSSON in Journal of Neurodevelopmental Disorders, 6-1 (December 2014)
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PermalinkPhysical health in children with neurodevelopmental disorders / S. ALABAF in Journal of Autism and Developmental Disorders, 49-1 (January 2019)
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PermalinkTrajectories leading to autism spectrum disorders are affected by paternal age: findings from two nationally representative twin studies / Sebastian LUNDSTROM in Journal of Child Psychology and Psychiatry, 51-7 (July 2010)
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