The cognitive developmental profile associated with fragile X syndrome: A longitudinal investigation of cognitive strengths and weaknesses through childhood and adolescence / Eve-Marie QUINTIN in Development and Psychopathology, 28-4 pt2 (November 2016)  

Public ISBD [article]  inDevelopment and Psychopathology > 28-4 pt2 (November 2016) . - p.1457-1469 Titre : The cognitive developmental profile associated with fragile X syndrome: A longitudinal investigation of cognitive strengths and weaknesses through childhood and adolescence Type de document : Texte imprimé et/ou numérique Auteurs : Eve-Marie QUINTIN, Auteur ; Booil JO, Auteur ; Scott S. HALL, Auteur ; Jennifer L. BRUNO, Auteur ; Lindsay C. CHROMIK, Auteur ; Mira M. RAMAN, Auteur ; Amy A. LIGHTBODY, Auteur ; Arianna MARTIN, Auteur ; Allan L. REISS, Auteur Article en page(s) : p.1457-1469 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Few studies have investigated developmental strengths and weaknesses within the cognitive profile of children and adolescents with fragile X syndrome (FXS), a single-gene cause of inherited intellectual impairment. With a prospective longitudinal design and using normalized raw scores (Z scores) to circumvent floor effects, we measured cognitive functioning of 184 children and adolescents with FXS (ages 6 to 16) using the Wechsler Scale of Intelligence for Children on one to three occasions for each participant. Participants with FXS received lower raw scores relative to the Wechsler Scale of Intelligence for Children normative sample across the developmental period. Verbal comprehension, perceptual organization, and processing speed Z scores were marked by a widening gap from the normative sample, while freedom from distractibility Z scores showed a narrowing gap. Key findings include a relative strength for verbal skills in comparison with visuospatial–constructive skills arising in adolescence and a discrepancy between working memory (weakness) and processing speed (strength) in childhood that diminishes in adolescence. Results suggest that the cognitive profile associated with FXS develops dynamically from childhood to adolescence. Findings are discussed within the context of aberrant brain morphology in childhood and maturation in adolescence. We argue that assessing disorder-specific cognitive developmental profiles will benefit future disorder-specific treatment research. En ligne : http://dx.doi.org/10.1017/s0954579415001200 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294 [article] The cognitive developmental profile associated with fragile X syndrome: A longitudinal investigation of cognitive strengths and weaknesses through childhood and adolescence [Texte imprimé et/ou numérique] / Eve-Marie QUINTIN, Auteur ; Booil JO, Auteur ; Scott S. HALL, Auteur ; Jennifer L. BRUNO, Auteur ; Lindsay C. CHROMIK, Auteur ; Mira M. RAMAN, Auteur ; Amy A. LIGHTBODY, Auteur ; Arianna MARTIN, Auteur ; Allan L. REISS, Auteur . - p.1457-1469. Langues : Anglais (eng) in Development and Psychopathology > 28-4 pt2 (November 2016) . - p.1457-1469 Index. décimale : PER Périodiques Résumé : Few studies have investigated developmental strengths and weaknesses within the cognitive profile of children and adolescents with fragile X syndrome (FXS), a single-gene cause of inherited intellectual impairment. With a prospective longitudinal design and using normalized raw scores (Z scores) to circumvent floor effects, we measured cognitive functioning of 184 children and adolescents with FXS (ages 6 to 16) using the Wechsler Scale of Intelligence for Children on one to three occasions for each participant. Participants with FXS received lower raw scores relative to the Wechsler Scale of Intelligence for Children normative sample across the developmental period. Verbal comprehension, perceptual organization, and processing speed Z scores were marked by a widening gap from the normative sample, while freedom from distractibility Z scores showed a narrowing gap. Key findings include a relative strength for verbal skills in comparison with visuospatial–constructive skills arising in adolescence and a discrepancy between working memory (weakness) and processing speed (strength) in childhood that diminishes in adolescence. Results suggest that the cognitive profile associated with FXS develops dynamically from childhood to adolescence. Findings are discussed within the context of aberrant brain morphology in childhood and maturation in adolescence. We argue that assessing disorder-specific cognitive developmental profiles will benefit future disorder-specific treatment research. En ligne : http://dx.doi.org/10.1017/s0954579415001200 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294

The Relationship Between Autistic Symptomatology and Independent Living Skills in Adolescents and Young Adults with Fragile X Syndrome / Kristin M. HUSTYI in Journal of Autism and Developmental Disorders, 45-6 (June 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-6 (June 2015) . - p.1836-1844 Titre : The Relationship Between Autistic Symptomatology and Independent Living Skills in Adolescents and Young Adults with Fragile X Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Kristin M. HUSTYI, Auteur ; Scott S. HALL, Auteur ; Eve-Marie QUINTIN, Auteur ; Lindsay C. CHROMIK, Auteur ; Amy A. LIGHTBODY, Auteur ; Allan L. REISS, Auteur Article en page(s) : p.1836-1844 Langues : Anglais (eng) Mots-clés : Fragile X syndrome  Functional skills  Independent living skills  Autistic symptomatology Index. décimale : PER Périodiques Résumé : Few studies have examined the relationship between autistic symptomatology and competence in independent living skills in adolescents and young adults with fragile X syndrome (FXS). In this study, 70 individuals with FXS, aged 15–25 years, and 35 matched controls were administered direct measures of independent living skills and autistic symptomatology. Results showed that higher levels of autistic symptomatology were associated with lower levels of competence in independent living skills in individuals with FXS, but not in controls. These data indicated that the relationship between autistic symptomatology and independent living skills was syndrome-specific. Early intervention strategies that address autistic symptomatology are sorely needed to improve functional outcomes in this population. En ligne : http://dx.doi.org/10.1007/s10803-014-2342-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259 [article] The Relationship Between Autistic Symptomatology and Independent Living Skills in Adolescents and Young Adults with Fragile X Syndrome [Texte imprimé et/ou numérique] / Kristin M. HUSTYI, Auteur ; Scott S. HALL, Auteur ; Eve-Marie QUINTIN, Auteur ; Lindsay C. CHROMIK, Auteur ; Amy A. LIGHTBODY, Auteur ; Allan L. REISS, Auteur . - p.1836-1844. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-6 (June 2015) . - p.1836-1844 Mots-clés : Fragile X syndrome  Functional skills  Independent living skills  Autistic symptomatology Index. décimale : PER Périodiques Résumé : Few studies have examined the relationship between autistic symptomatology and competence in independent living skills in adolescents and young adults with fragile X syndrome (FXS). In this study, 70 individuals with FXS, aged 15–25 years, and 35 matched controls were administered direct measures of independent living skills and autistic symptomatology. Results showed that higher levels of autistic symptomatology were associated with lower levels of competence in independent living skills in individuals with FXS, but not in controls. These data indicated that the relationship between autistic symptomatology and independent living skills was syndrome-specific. Early intervention strategies that address autistic symptomatology are sorely needed to improve functional outcomes in this population. En ligne : http://dx.doi.org/10.1007/s10803-014-2342-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259

---

1 (1 - 2 / 2)