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Détail de l'auteur
Auteur Cleonice Alves BOSA |
Documents disponibles écrits par cet auteur (2)
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Identifying Autism with a Brief and Low-Cost Screening Instrument-OERA: Construct Validity, Invariance Testing, and Agreement Between Judges / C. S. PAULA in Journal of Autism and Developmental Disorders, 48-5 (May 2018)
[article]
Titre : Identifying Autism with a Brief and Low-Cost Screening Instrument-OERA: Construct Validity, Invariance Testing, and Agreement Between Judges Type de document : Texte imprimé et/ou numérique Auteurs : C. S. PAULA, Auteur ; G. R. CUNHA, Auteur ; Daniela BORDINI, Auteur ; Décio BRUNONI, Auteur ; A. C. MOYA, Auteur ; Cleonice Alves BOSA, Auteur ; J. J. MARI, Auteur ; H. COGO-MOREIRA, Auteur Article en page(s) : p.1780-1791 Langues : Anglais (eng) Mots-clés : Autism Construct validity Public health Screening Sensitivity Specificity Index. décimale : PER Périodiques Résumé : Simple and low-cost observational-tools to detect symptoms of Autism Spectrum Disorder (ASD) are still necessary. The OERA is a new assessment tool to screen children eliciting observable behaviors with no substantial knowledge on ASD required. The sample was 99 children aged 3-10: 76 with ASD and 23 without ASD (11/23 had intellectual disability). The 13 remained items exhibited high interrater agreement and high reliability loaded onto a single latent trait. Such model showed excellent fit indices evaluated via confirmatory factor analysis and no item showed differential function in terms of age/sex/IQ. A cutoff of five points or higher resulted in the highest sensitivity (92.75) and specificity (90.91) percentages. OERA is a brief, stable, low-cost standardized observational-screening to identify ASD children. En ligne : http://dx.doi.org/10.1007/s10803-017-3440-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=355
in Journal of Autism and Developmental Disorders > 48-5 (May 2018) . - p.1780-1791[article] Identifying Autism with a Brief and Low-Cost Screening Instrument-OERA: Construct Validity, Invariance Testing, and Agreement Between Judges [Texte imprimé et/ou numérique] / C. S. PAULA, Auteur ; G. R. CUNHA, Auteur ; Daniela BORDINI, Auteur ; Décio BRUNONI, Auteur ; A. C. MOYA, Auteur ; Cleonice Alves BOSA, Auteur ; J. J. MARI, Auteur ; H. COGO-MOREIRA, Auteur . - p.1780-1791.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 48-5 (May 2018) . - p.1780-1791
Mots-clés : Autism Construct validity Public health Screening Sensitivity Specificity Index. décimale : PER Périodiques Résumé : Simple and low-cost observational-tools to detect symptoms of Autism Spectrum Disorder (ASD) are still necessary. The OERA is a new assessment tool to screen children eliciting observable behaviors with no substantial knowledge on ASD required. The sample was 99 children aged 3-10: 76 with ASD and 23 without ASD (11/23 had intellectual disability). The 13 remained items exhibited high interrater agreement and high reliability loaded onto a single latent trait. Such model showed excellent fit indices evaluated via confirmatory factor analysis and no item showed differential function in terms of age/sex/IQ. A cutoff of five points or higher resulted in the highest sensitivity (92.75) and specificity (90.91) percentages. OERA is a brief, stable, low-cost standardized observational-screening to identify ASD children. En ligne : http://dx.doi.org/10.1007/s10803-017-3440-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=355 Psychomotor agitation and mood instability in patients with autism spectrum disorders: A possible effect of SLC6A4 gene? / Jaqueline Bohrer SCHUCH in Research in Autism Spectrum Disorders, 26 (June 2016)
[article]
Titre : Psychomotor agitation and mood instability in patients with autism spectrum disorders: A possible effect of SLC6A4 gene? Type de document : Texte imprimé et/ou numérique Auteurs : Jaqueline Bohrer SCHUCH, Auteur ; Diana MÜLLER, Auteur ; Renata Giuliani ENDRES, Auteur ; Cleonice Alves BOSA, Auteur ; Dânae LONGO, Auteur ; Lavinia SCHULER-FACCINI, Auteur ; Josiane RANZAN, Auteur ; Michele Michelin BECKER, Auteur ; Rudimar dos Santos RIESGO, Auteur ; Tatiana ROMAN, Auteur Article en page(s) : p.48-56 Langues : Anglais (eng) Mots-clés : ASD Serotonin transporter gene Clinical symptoms Sex differences Association Family-based test Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) are a group of neurodevelopmental conditions characterized by impairments in communication and social interaction and repetitive and stereotyped behaviors. Serotoninergic transmission has been suggested as an important neuronal pathway in ASD. In this study, we analyzed four polymorphisms (5HTTLPR, rs2066713, STin2, rs1042173; 5? ? 3? end) at the serotonin transporter gene (SLC6A4) in a sample of 209 ASD children and their biological parents. Both single markers and haplotypes were tested for association with ASD diagnosis and with clinical symptoms (aggression, echolalia, seizures, mood instability, psychomotor agitation, repetitive behaviors and sleep disorders) commonly present in ASD patients. The family-based analyses showed a significant result for one haplotype (H4: S-G-12R-T), which did not hold in global analyses. In male patients, a nominal association between the rs1042173 GG genotype and a diminished psychomotor agitation was observed; a trend for an association between the 5HTTLPR LaLa genotype and mood instability was also verified. Through interesting results that are mainly related to clinical manifestations and gender differences, our study adds to knowledge of ASD. Future investigations may corroborate the relevance of our data to upcoming clinical and pharmacological interventions. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.03.001 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=285
in Research in Autism Spectrum Disorders > 26 (June 2016) . - p.48-56[article] Psychomotor agitation and mood instability in patients with autism spectrum disorders: A possible effect of SLC6A4 gene? [Texte imprimé et/ou numérique] / Jaqueline Bohrer SCHUCH, Auteur ; Diana MÜLLER, Auteur ; Renata Giuliani ENDRES, Auteur ; Cleonice Alves BOSA, Auteur ; Dânae LONGO, Auteur ; Lavinia SCHULER-FACCINI, Auteur ; Josiane RANZAN, Auteur ; Michele Michelin BECKER, Auteur ; Rudimar dos Santos RIESGO, Auteur ; Tatiana ROMAN, Auteur . - p.48-56.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 26 (June 2016) . - p.48-56
Mots-clés : ASD Serotonin transporter gene Clinical symptoms Sex differences Association Family-based test Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) are a group of neurodevelopmental conditions characterized by impairments in communication and social interaction and repetitive and stereotyped behaviors. Serotoninergic transmission has been suggested as an important neuronal pathway in ASD. In this study, we analyzed four polymorphisms (5HTTLPR, rs2066713, STin2, rs1042173; 5? ? 3? end) at the serotonin transporter gene (SLC6A4) in a sample of 209 ASD children and their biological parents. Both single markers and haplotypes were tested for association with ASD diagnosis and with clinical symptoms (aggression, echolalia, seizures, mood instability, psychomotor agitation, repetitive behaviors and sleep disorders) commonly present in ASD patients. The family-based analyses showed a significant result for one haplotype (H4: S-G-12R-T), which did not hold in global analyses. In male patients, a nominal association between the rs1042173 GG genotype and a diminished psychomotor agitation was observed; a trend for an association between the 5HTTLPR LaLa genotype and mood instability was also verified. Through interesting results that are mainly related to clinical manifestations and gender differences, our study adds to knowledge of ASD. Future investigations may corroborate the relevance of our data to upcoming clinical and pharmacological interventions. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.03.001 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=285