Attentional functions in children and adolescents with ADHD, depressive disorders, and the comorbid condition / Thomas GUNTHER in Journal of Child Psychology and Psychiatry, 52-3 (March 2011)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 52-3 (March 2011) . - p.324-331 Titre : Attentional functions in children and adolescents with ADHD, depressive disorders, and the comorbid condition Type de document : Texte imprimé et/ou numérique Auteurs : Thomas GUNTHER, Auteur ; Kerstin KONRAD, Auteur ; Stephane A. DE BRITO, Auteur ; Beate HERPERTZ-DAHLMANN, Auteur ; Timo D. VLOET, Auteur Année de publication : 2011 Article en page(s) : p.324-331 Langues : Anglais (eng) Mots-clés : ADHD  depression  attention  neuropsychology Index. décimale : PER Périodiques Résumé : Background:  Attention-deficit hyperactivity disorder (ADHD) and depressive disorders (DDs) often co-occur in children and adolescents, but evidence on the respective influence of these disorders on attention parameters is inconsistent. This study examines the influence of DDs on ADHD in a model-oriented approach that includes selectivity and intensity attention parameters. Methods:  Ten- to fifteen-year-olds with ADHD (n = 63), DDs (n = 61), ADHD+DDs (n = 64), and healthy controls (n = 64) completed a battery of tests including five neuropsychological tasks (i.e., alertness, sustained attention, divided attention, go/no-go, and attentional set-shifting). Results:  All clinical groups showed attentional problems, especially in more complex attentional tasks and in the intensity aspects of attention. We observed the most severe attentional impairments in children with ADHD that was independent from a comorbid DD. Conclusion:  The clinical groups were significantly different from the healthy control group, especially in more complex attentional tasks and in the intensity aspects of attention. Some differences between ADHD, DDs and ADHD+DDs groups were detected on neuropsychological attentional performance, but the effects were not strong enough to differentiate the clinical groups from each other. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02320.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=118 [article] Attentional functions in children and adolescents with ADHD, depressive disorders, and the comorbid condition [Texte imprimé et/ou numérique] / Thomas GUNTHER, Auteur ; Kerstin KONRAD, Auteur ; Stephane A. DE BRITO, Auteur ; Beate HERPERTZ-DAHLMANN, Auteur ; Timo D. VLOET, Auteur . - 2011 . - p.324-331. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 52-3 (March 2011) . - p.324-331 Mots-clés : ADHD  depression  attention  neuropsychology Index. décimale : PER Périodiques Résumé : Background:  Attention-deficit hyperactivity disorder (ADHD) and depressive disorders (DDs) often co-occur in children and adolescents, but evidence on the respective influence of these disorders on attention parameters is inconsistent. This study examines the influence of DDs on ADHD in a model-oriented approach that includes selectivity and intensity attention parameters. Methods:  Ten- to fifteen-year-olds with ADHD (n = 63), DDs (n = 61), ADHD+DDs (n = 64), and healthy controls (n = 64) completed a battery of tests including five neuropsychological tasks (i.e., alertness, sustained attention, divided attention, go/no-go, and attentional set-shifting). Results:  All clinical groups showed attentional problems, especially in more complex attentional tasks and in the intensity aspects of attention. We observed the most severe attentional impairments in children with ADHD that was independent from a comorbid DD. Conclusion:  The clinical groups were significantly different from the healthy control group, especially in more complex attentional tasks and in the intensity aspects of attention. Some differences between ADHD, DDs and ADHD+DDs groups were detected on neuropsychological attentional performance, but the effects were not strong enough to differentiate the clinical groups from each other. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02320.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=118

Atypical Brain Responses to Reward Cues in Autism as Revealed by Event-Related Potentials / Gregor KOHLS in Journal of Autism and Developmental Disorders, 41-11 (November 2011)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 41-11 (November 2011) . - p.1523-1533 Titre : Atypical Brain Responses to Reward Cues in Autism as Revealed by Event-Related Potentials Type de document : Texte imprimé et/ou numérique Auteurs : Gregor KOHLS, Auteur ; Judith PELTZER, Auteur ; Martin SCHULTE-RUTHER, Auteur ; Inge KAMP-BECKER, Auteur ; Helmut REMSCHMIDT, Auteur ; Beate HERPERTZ-DAHLMANN, Auteur ; Kerstin KONRAD, Auteur Année de publication : 2011 Article en page(s) : p.1523-1533 Langues : Anglais (eng) Mots-clés : Social reward  Monetary reward  Motivation  Autism spectrum disorders  Event-related brain potentials  P3  Go/no-go task Index. décimale : PER Périodiques Résumé : Social motivation deficit theories suggest that children with autism do not properly anticipate and appreciate the pleasure of social stimuli. In this study, we investigated event-related brain potentials evoked by cues that triggered social versus monetary reward anticipation in children with autism. Children with autism showed attenuated P3 activity in response to cues associated with a timely reaction to obtain a reward, irrespective of reward type. We attribute this atypical P3 activity in response to reward cues as reflective of diminished motivated attention to reward signals, a possible contributor to reduced social motivation in autism. Thus, our findings suggest a general reward processing deficit rather than a specific social reward dysfunction in autism. En ligne : http://dx.doi.org/10.1007/s10803-011-1177-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=147 [article] Atypical Brain Responses to Reward Cues in Autism as Revealed by Event-Related Potentials [Texte imprimé et/ou numérique] / Gregor KOHLS, Auteur ; Judith PELTZER, Auteur ; Martin SCHULTE-RUTHER, Auteur ; Inge KAMP-BECKER, Auteur ; Helmut REMSCHMIDT, Auteur ; Beate HERPERTZ-DAHLMANN, Auteur ; Kerstin KONRAD, Auteur . - 2011 . - p.1523-1533. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 41-11 (November 2011) . - p.1523-1533 Mots-clés : Social reward  Monetary reward  Motivation  Autism spectrum disorders  Event-related brain potentials  P3  Go/no-go task Index. décimale : PER Périodiques Résumé : Social motivation deficit theories suggest that children with autism do not properly anticipate and appreciate the pleasure of social stimuli. In this study, we investigated event-related brain potentials evoked by cues that triggered social versus monetary reward anticipation in children with autism. Children with autism showed attenuated P3 activity in response to cues associated with a timely reaction to obtain a reward, irrespective of reward type. We attribute this atypical P3 activity in response to reward cues as reflective of diminished motivated attention to reward signals, a possible contributor to reduced social motivation in autism. Thus, our findings suggest a general reward processing deficit rather than a specific social reward dysfunction in autism. En ligne : http://dx.doi.org/10.1007/s10803-011-1177-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=147

Atypical Laterality of Resting Gamma Oscillations in Autism Spectrum Disorders / Christina R. MAXWELL in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.292-297 Titre : Atypical Laterality of Resting Gamma Oscillations in Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Christina R. MAXWELL, Auteur ; Michele E. VILLALOBOS, Auteur ; Robert T. SCHULTZ, Auteur ; Beate HERPERTZ-DAHLMANN, Auteur ; Kerstin KONRAD, Auteur ; Gregor KOHLS, Auteur Article en page(s) : p.292-297 Langues : Anglais (eng) Mots-clés : Autism  Gamma  EEG  SRS  Resting state  Laterality Index. décimale : PER Périodiques Résumé : Abnormal brain oscillatory activity has been found in autism spectrum disorders (ASD) and proposed as a potential biomarker. While several studies have investigated gamma oscillations in ASD, none have examined resting gamma power across multiple brain regions. This study investigated resting gamma power using EEG in 15 boys with ASD and 18 age and intelligence quotient matched typically developing controls. We found a decrease in resting gamma power at right lateral electrodes in ASD. We further explored associations between gamma and ASD severity as measured by the Social Responsiveness Scale (SRS) and found a negative correlation between SRS and gamma power. We believe that our findings give further support of gamma oscillations as a potential biomarker for ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1842-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Atypical Laterality of Resting Gamma Oscillations in Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Christina R. MAXWELL, Auteur ; Michele E. VILLALOBOS, Auteur ; Robert T. SCHULTZ, Auteur ; Beate HERPERTZ-DAHLMANN, Auteur ; Kerstin KONRAD, Auteur ; Gregor KOHLS, Auteur . - p.292-297. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.292-297 Mots-clés : Autism  Gamma  EEG  SRS  Resting state  Laterality Index. décimale : PER Périodiques Résumé : Abnormal brain oscillatory activity has been found in autism spectrum disorders (ASD) and proposed as a potential biomarker. While several studies have investigated gamma oscillations in ASD, none have examined resting gamma power across multiple brain regions. This study investigated resting gamma power using EEG in 15 boys with ASD and 18 age and intelligence quotient matched typically developing controls. We found a decrease in resting gamma power at right lateral electrodes in ASD. We further explored associations between gamma and ASD severity as measured by the Social Responsiveness Scale (SRS) and found a negative correlation between SRS and gamma power. We believe that our findings give further support of gamma oscillations as a potential biomarker for ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1842-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Emotional processing in male adolescents with childhood-onset conduct disorder / Sabine C. HERPERTZ in Journal of Child Psychology and Psychiatry, 49-7 (July 2008)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 49-7 (July 2008) . - p.781 - 791 Titre : Emotional processing in male adolescents with childhood-onset conduct disorder Type de document : Texte imprimé et/ou numérique Auteurs : Sabine C. HERPERTZ, Auteur ; Beate HERPERTZ-DAHLMANN, Auteur ; Gereon R. FINK, Auteur ; Kerstin KONRAD, Auteur ; Thomas HUEBNER, Auteur ; Ivo MARX, Auteur ; Timo D. VLOET, Auteur ; Tony STOECKER, Auteur ; N. Jon SHAH, Auteur Année de publication : 2008 Article en page(s) : p.781 - 791 Langues : Anglais (eng) Mots-clés : Conduct-disorder fMRI emotion antisocial-behavior amygdala antisocial-personality-disorder Index. décimale : PER Périodiques Résumé : Background: Boys with early onset of conduct disorder (CD), most of whom also meet diagnostic criteria of a comorbid attention deficit hyperactivity disorder (ADHD), tend to exhibit high levels of aggression throughout development. While a number of functional neuroimaging studies on emotional processing have been performed in antisocial adults, little is known about how CD children process emotional information. Method: Functional magnetic resonance imaging data were analyzed in 22 male adolescents aged 12 to 17 years with childhood-onset CD (16 of them with comorbid ADHD) compared to 22 age-matched male healthy controls. In order to consider the likely confounding of results through ADHD comorbidity, we performed a supplementary study including 13 adolescent subjects with pure ADHD who were compared with healthy controls. To challenge emotional processing of stimuli, a passive viewing task was applied, presenting pictures of negative, positive or neutral valence. Results: When comparing CD/combined disorder patients with healthy controls, we found enhanced left-sided amygdala activation in response to negative pictures as compared to neutral pictures in the patient group. In addition, these boys exhibited no reduced activation in the orbitofrontal, anterior cingulate and insular cortices. By contrast, children with pure ADHD did not show any abnormalities in amygdala activation but showed decreased neural activity in the insula only in response to negative pictures. Conclusions: Increased rather than reduced amygdala activation found in our study may indicate an enhanced response to environmental cues in adolescents with early-onset CD (most of whom also met the condition of ADHD), and is not consistent with the assumption of a reduced capacity to take note of affective information in the social environment. Further studies with an emphasis on developmental aspects of affect regulation are needed to clarify the relationship between CD and adult personality pathology associated with different modes of persistent antisocial behavior. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01905.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=541 [article] Emotional processing in male adolescents with childhood-onset conduct disorder [Texte imprimé et/ou numérique] / Sabine C. HERPERTZ, Auteur ; Beate HERPERTZ-DAHLMANN, Auteur ; Gereon R. FINK, Auteur ; Kerstin KONRAD, Auteur ; Thomas HUEBNER, Auteur ; Ivo MARX, Auteur ; Timo D. VLOET, Auteur ; Tony STOECKER, Auteur ; N. Jon SHAH, Auteur . - 2008 . - p.781 - 791. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 49-7 (July 2008) . - p.781 - 791 Mots-clés : Conduct-disorder fMRI emotion antisocial-behavior amygdala antisocial-personality-disorder Index. décimale : PER Périodiques Résumé : Background: Boys with early onset of conduct disorder (CD), most of whom also meet diagnostic criteria of a comorbid attention deficit hyperactivity disorder (ADHD), tend to exhibit high levels of aggression throughout development. While a number of functional neuroimaging studies on emotional processing have been performed in antisocial adults, little is known about how CD children process emotional information. Method: Functional magnetic resonance imaging data were analyzed in 22 male adolescents aged 12 to 17 years with childhood-onset CD (16 of them with comorbid ADHD) compared to 22 age-matched male healthy controls. In order to consider the likely confounding of results through ADHD comorbidity, we performed a supplementary study including 13 adolescent subjects with pure ADHD who were compared with healthy controls. To challenge emotional processing of stimuli, a passive viewing task was applied, presenting pictures of negative, positive or neutral valence. Results: When comparing CD/combined disorder patients with healthy controls, we found enhanced left-sided amygdala activation in response to negative pictures as compared to neutral pictures in the patient group. In addition, these boys exhibited no reduced activation in the orbitofrontal, anterior cingulate and insular cortices. By contrast, children with pure ADHD did not show any abnormalities in amygdala activation but showed decreased neural activity in the insula only in response to negative pictures. Conclusions: Increased rather than reduced amygdala activation found in our study may indicate an enhanced response to environmental cues in adolescents with early-onset CD (most of whom also met the condition of ADHD), and is not consistent with the assumption of a reduced capacity to take note of affective information in the social environment. Further studies with an emphasis on developmental aspects of affect regulation are needed to clarify the relationship between CD and adult personality pathology associated with different modes of persistent antisocial behavior. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01905.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=541

Group-based cognitive behavioural psychotherapy for children and adolescents with ASD: the randomized, multicentre, controlled SOSTA – net trial / Christine M. FREITAG in Journal of Child Psychology and Psychiatry, 57-5 (May 2016)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 57-5 (May 2016) . - p.596-605 Titre : Group-based cognitive behavioural psychotherapy for children and adolescents with ASD: the randomized, multicentre, controlled SOSTA – net trial Type de document : Texte imprimé et/ou numérique Auteurs : Christine M. FREITAG, Auteur ; Katrin JENSEN, Auteur ; Leyla ELSUNI, Auteur ; Michael SACHSE, Auteur ; Beate HERPERTZ-DAHLMANN, Auteur ; Martin SCHULTE-RUTHER, Auteur ; Susann HÄNIG, Auteur ; Alexander VON GONTARD, Auteur ; Luise POUSTKA, Auteur ; Tanja SCHAD-HANSJOSTEN, Auteur ; Christina WENZL, Auteur ; Judith SINZIG, Auteur ; Regina TAURINES, Auteur ; Julia GEIßLER, Auteur ; Meinhard KIESER, Auteur ; Hannah CHOLEMKERY, Auteur Article en page(s) : p.596-605 Langues : Anglais (eng) Mots-clés : Group therapy  social skills  autism spectrum disorders  randomized-controlled trial Index. décimale : PER Périodiques Résumé : Background Group-based psychotherapy in Autism Spectrum Disorder (ASD) has predominantly been studied in the United States by small studies in school-aged children without long-term follow-up. We report results of a large, confirmatory, multicentre randomized-controlled phase-III trial in children and adolescents studying the ASD specific, manualized group-based cognitive behavioural SOSTA-FRA approach. Methods High-functioning ASD individuals aged 8–19 years old were randomized to 12 sessions SOSTA-FRA or treatment as usual. Primary outcomes were change in total raw score of the parent-rated Social Responsiveness Scale (pSRS) between baseline (T2) and end of intervention (T4), and between T2 and 3 months after end of intervention (T5). Trial registration: ISRCTN94863788. Results Between 20/5/2010 and 14/2/2013, n = 320 ASD patients were screened, n = 228 patients were randomized, and N = 209 analysed. Mean pSRS difference between groups at T4 was ?6.5 (95% CI ?11.6 to – 1.4; p = .013), and at T5 ?6.4 (?11.5 to ?1.3, p = .015). Pre-treatment SRS and IQ were positively associated with stronger improvement at T4 and T5. Conclusions Short-term ASD-specific add-on group-based psychotherapy has shown postintervention efficacy with regard to parent-rated social responsiveness predominantly in male high-functioning children and adolescents with ASD. Future studies should implement blinded standardized observational measures of peer-related social interaction. En ligne : http://dx.doi.org/10.1111/jcpp.12509 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=288 [article] Group-based cognitive behavioural psychotherapy for children and adolescents with ASD: the randomized, multicentre, controlled SOSTA – net trial [Texte imprimé et/ou numérique] / Christine M. FREITAG, Auteur ; Katrin JENSEN, Auteur ; Leyla ELSUNI, Auteur ; Michael SACHSE, Auteur ; Beate HERPERTZ-DAHLMANN, Auteur ; Martin SCHULTE-RUTHER, Auteur ; Susann HÄNIG, Auteur ; Alexander VON GONTARD, Auteur ; Luise POUSTKA, Auteur ; Tanja SCHAD-HANSJOSTEN, Auteur ; Christina WENZL, Auteur ; Judith SINZIG, Auteur ; Regina TAURINES, Auteur ; Julia GEIßLER, Auteur ; Meinhard KIESER, Auteur ; Hannah CHOLEMKERY, Auteur . - p.596-605. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 57-5 (May 2016) . - p.596-605 Mots-clés : Group therapy  social skills  autism spectrum disorders  randomized-controlled trial Index. décimale : PER Périodiques Résumé : Background Group-based psychotherapy in Autism Spectrum Disorder (ASD) has predominantly been studied in the United States by small studies in school-aged children without long-term follow-up. We report results of a large, confirmatory, multicentre randomized-controlled phase-III trial in children and adolescents studying the ASD specific, manualized group-based cognitive behavioural SOSTA-FRA approach. Methods High-functioning ASD individuals aged 8–19 years old were randomized to 12 sessions SOSTA-FRA or treatment as usual. Primary outcomes were change in total raw score of the parent-rated Social Responsiveness Scale (pSRS) between baseline (T2) and end of intervention (T4), and between T2 and 3 months after end of intervention (T5). Trial registration: ISRCTN94863788. Results Between 20/5/2010 and 14/2/2013, n = 320 ASD patients were screened, n = 228 patients were randomized, and N = 209 analysed. Mean pSRS difference between groups at T4 was ?6.5 (95% CI ?11.6 to – 1.4; p = .013), and at T5 ?6.4 (?11.5 to ?1.3, p = .015). Pre-treatment SRS and IQ were positively associated with stronger improvement at T4 and T5. Conclusions Short-term ASD-specific add-on group-based psychotherapy has shown postintervention efficacy with regard to parent-rated social responsiveness predominantly in male high-functioning children and adolescents with ASD. Future studies should implement blinded standardized observational measures of peer-related social interaction. En ligne : http://dx.doi.org/10.1111/jcpp.12509 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=288

Implicit sequence learning in juvenile anorexia nervosa: neural mechanisms and the impact of starvation / Christine FIRK in Journal of Child Psychology and Psychiatry, 56-11 (November 2015)  

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Intact mirror mechanisms for automatic facial emotions in children and adolescents with autism spectrum disorder / Martin SCHULTE-RUTHER in Autism Research, 10-2 (February 2017)  

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A mother–child intervention program for adolescent mothers: Results from a randomized controlled trial (the TeeMo study) / Christine FIRK in Development and Psychopathology, 33-3 (August 2021)  

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Positive and negative parenting in conduct disorder with high versus low levels of callous–unemotional traits / Ruth PAULI in Development and Psychopathology, 33-3 (August 2021)  

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Structural brain abnormalities in adolescents with autism spectrum disorder and patients with attention deficit/hyperactivity disorder / Sarah BRIEBER in Journal of Child Psychology and Psychiatry, 48-12 (December 2007)  

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