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Auteur Makoto WADA |
Documents disponibles écrits par cet auteur (3)
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Altered GABA Concentration in Brain Motor Area Is Associated with the Severity of Motor Disabilities in Individuals with Autism Spectrum Disorder / Yumi UMESAWA in Journal of Autism and Developmental Disorders, 50-8 (August 2020)
[article]
Titre : Altered GABA Concentration in Brain Motor Area Is Associated with the Severity of Motor Disabilities in Individuals with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Yumi UMESAWA, Auteur ; Kanae MATSUSHIMA, Auteur ; Takeshi ATSUMI, Auteur ; Toshihiro KATO, Auteur ; Reiko FUKATSU, Auteur ; Makoto WADA, Auteur ; Masakazu IDE, Auteur Article en page(s) : p.2710-2722 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Developmental coordination disorder Gamma-aminobutyric acid Magnetic resonance spectroscopy Primary motor area Supplementary motor area Index. décimale : PER Périodiques Résumé : Several motor disabilities accompanied with autism spectrum disorder (ASD) are widely known despite limited reports of underlying neural mechanisms. Gamma-aminobutyric acid (GABA) levels in the motor-related cortical areas modulate several motor performances in healthy participants. We hypothesized that abnormal GABA concentrations in the primary motor area (M1) and supplementary motor area (SMA) associate with different motor difficulties for ASD adolescents/adults. We found that increased GABA concentrations in M1 measured using (1)H-magnetic resonance spectroscopy exhibited lower motor performance in tasks requiring increased muscle strength while lower GABA concentrations in SMA were associated with lower scores in tests measuring body coordination. The degrees of neural inhibition in the M1 and SMA regions would contribute to different dimensions of motor disabilities in autism. En ligne : http://dx.doi.org/10.1007/s10803-020-04382-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=428
in Journal of Autism and Developmental Disorders > 50-8 (August 2020) . - p.2710-2722[article] Altered GABA Concentration in Brain Motor Area Is Associated with the Severity of Motor Disabilities in Individuals with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Yumi UMESAWA, Auteur ; Kanae MATSUSHIMA, Auteur ; Takeshi ATSUMI, Auteur ; Toshihiro KATO, Auteur ; Reiko FUKATSU, Auteur ; Makoto WADA, Auteur ; Masakazu IDE, Auteur . - p.2710-2722.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 50-8 (August 2020) . - p.2710-2722
Mots-clés : Autism spectrum disorder Developmental coordination disorder Gamma-aminobutyric acid Magnetic resonance spectroscopy Primary motor area Supplementary motor area Index. décimale : PER Périodiques Résumé : Several motor disabilities accompanied with autism spectrum disorder (ASD) are widely known despite limited reports of underlying neural mechanisms. Gamma-aminobutyric acid (GABA) levels in the motor-related cortical areas modulate several motor performances in healthy participants. We hypothesized that abnormal GABA concentrations in the primary motor area (M1) and supplementary motor area (SMA) associate with different motor difficulties for ASD adolescents/adults. We found that increased GABA concentrations in M1 measured using (1)H-magnetic resonance spectroscopy exhibited lower motor performance in tasks requiring increased muscle strength while lower GABA concentrations in SMA were associated with lower scores in tests measuring body coordination. The degrees of neural inhibition in the M1 and SMA regions would contribute to different dimensions of motor disabilities in autism. En ligne : http://dx.doi.org/10.1007/s10803-020-04382-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=428 No differences in implicit hand maps among different degrees of autistic traits / Souta HIDAKA in Autism Research, 16-9 (September 2023)
[article]
Titre : No differences in implicit hand maps among different degrees of autistic traits Type de document : Texte imprimé et/ou numérique Auteurs : Souta HIDAKA, Auteur ; Na CHEN, Auteur ; Naomi ISHII, Auteur ; Risa IKETANI, Auteur ; Kirino SUZUKI, Auteur ; Matthew R. LONGO, Auteur ; Makoto WADA, Auteur Article en page(s) : p.1750-1764 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract People with autism spectrum disorder (ASD) or higher levels of autistic traits have atypical characteristics in sensory processing. Atypicalities have been reported for proprioceptive judgments, which are tightly related to internal bodily representations underlying position sense. However, no research has directly investigated whether self-bodily representations are different in individuals with ASD. Implicit hand maps, estimated based on participants' proprioceptive sensations without sight of their hand, are known to be distorted such that the shape is stretched along the medio-lateral hand axis even for neurotypical participants. Here, with the view of ASD as falling on a continuous distribution among the general population, we explored differences in implicit body representations along with autistic traits by focusing on relationships between autistic traits and the magnitudes of the distortions in implicit hand maps (N?~?100). We estimated the magnitudes of distortions in implicit hand maps both for fingers and hand surfaces on the dorsal and palmar sides of the hand. Autistic traits were measured by questionnaires (Autism Spectrum [AQ] and Empathy/Systemizing [EQ-SQ] Quotients). The distortions in implicit hand maps were replicated in our experimental situations. However, there were no significant relationships between autistic traits and the magnitudes of the distortions as well as within-individual variabilities in the maps and localization performances. Consistent results were observed from comparisons between IQ-matched samples of people with and without a diagnosis of ASD. Our findings suggest that there exist perceptual and neural processes for implicit body representations underlying position sense consistent across levels of autistic traits. En ligne : https://doi.org/10.1002/aur.2979 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510
in Autism Research > 16-9 (September 2023) . - p.1750-1764[article] No differences in implicit hand maps among different degrees of autistic traits [Texte imprimé et/ou numérique] / Souta HIDAKA, Auteur ; Na CHEN, Auteur ; Naomi ISHII, Auteur ; Risa IKETANI, Auteur ; Kirino SUZUKI, Auteur ; Matthew R. LONGO, Auteur ; Makoto WADA, Auteur . - p.1750-1764.
Langues : Anglais (eng)
in Autism Research > 16-9 (September 2023) . - p.1750-1764
Index. décimale : PER Périodiques Résumé : Abstract People with autism spectrum disorder (ASD) or higher levels of autistic traits have atypical characteristics in sensory processing. Atypicalities have been reported for proprioceptive judgments, which are tightly related to internal bodily representations underlying position sense. However, no research has directly investigated whether self-bodily representations are different in individuals with ASD. Implicit hand maps, estimated based on participants' proprioceptive sensations without sight of their hand, are known to be distorted such that the shape is stretched along the medio-lateral hand axis even for neurotypical participants. Here, with the view of ASD as falling on a continuous distribution among the general population, we explored differences in implicit body representations along with autistic traits by focusing on relationships between autistic traits and the magnitudes of the distortions in implicit hand maps (N?~?100). We estimated the magnitudes of distortions in implicit hand maps both for fingers and hand surfaces on the dorsal and palmar sides of the hand. Autistic traits were measured by questionnaires (Autism Spectrum [AQ] and Empathy/Systemizing [EQ-SQ] Quotients). The distortions in implicit hand maps were replicated in our experimental situations. However, there were no significant relationships between autistic traits and the magnitudes of the distortions as well as within-individual variabilities in the maps and localization performances. Consistent results were observed from comparisons between IQ-matched samples of people with and without a diagnosis of ASD. Our findings suggest that there exist perceptual and neural processes for implicit body representations underlying position sense consistent across levels of autistic traits. En ligne : https://doi.org/10.1002/aur.2979 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 Weakened Bayesian Calibration for Tactile Temporal Order Judgment in Individuals with Higher Autistic Traits / Makoto WADA in Journal of Autism and Developmental Disorders, 53-1 (January 2023)
[article]
Titre : Weakened Bayesian Calibration for Tactile Temporal Order Judgment in Individuals with Higher Autistic Traits Type de document : Texte imprimé et/ou numérique Auteurs : Makoto WADA, Auteur ; Yumi UMESAWA, Auteur ; Misako SANO, Auteur ; Seiki TAJIMA, Auteur ; Shinichiro KUMAGAYA, Auteur ; Makoto MIYAZAKI, Auteur Article en page(s) : p.378-389 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Previous psychophysical studies reported a positive aftereffect in tactile temporal order judgments, which can be explained by the Bayesian estimation model ( ˜Bayesian calibration’). We investigated the relationship between Bayesian calibration and autistic traits in participants with typical development (TD) and autism spectrum disorder (ASD). Bayesian calibration was weakened in TD participants with high autistic traits, consistent with the ˜hypo-priors’ hypothesis for autistic perceptions. The results from the ASD group were generally observed as a continuation of those from the TD groups. Meanwhile, two ASD participants showed irregularly large positive or negative aftereffects. We discussed the mechanisms behind the general results among TD and ASD participants and two particular results among ASD participants based on the Bayesian estimation model. En ligne : https://doi.org/10.1007/s10803-022-05442-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=493
in Journal of Autism and Developmental Disorders > 53-1 (January 2023) . - p.378-389[article] Weakened Bayesian Calibration for Tactile Temporal Order Judgment in Individuals with Higher Autistic Traits [Texte imprimé et/ou numérique] / Makoto WADA, Auteur ; Yumi UMESAWA, Auteur ; Misako SANO, Auteur ; Seiki TAJIMA, Auteur ; Shinichiro KUMAGAYA, Auteur ; Makoto MIYAZAKI, Auteur . - p.378-389.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 53-1 (January 2023) . - p.378-389
Index. décimale : PER Périodiques Résumé : Previous psychophysical studies reported a positive aftereffect in tactile temporal order judgments, which can be explained by the Bayesian estimation model ( ˜Bayesian calibration’). We investigated the relationship between Bayesian calibration and autistic traits in participants with typical development (TD) and autism spectrum disorder (ASD). Bayesian calibration was weakened in TD participants with high autistic traits, consistent with the ˜hypo-priors’ hypothesis for autistic perceptions. The results from the ASD group were generally observed as a continuation of those from the TD groups. Meanwhile, two ASD participants showed irregularly large positive or negative aftereffects. We discussed the mechanisms behind the general results among TD and ASD participants and two particular results among ASD participants based on the Bayesian estimation model. En ligne : https://doi.org/10.1007/s10803-022-05442-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=493