Cybervictimization in adolescence and its association with subsequent suicidal ideation/attempt beyond face-to-face victimization: a longitudinal population-based study / Léa C. PERRET in Journal of Child Psychology and Psychiatry, 61-8 (August 2020)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 61-8 (August 2020) . - p.866-874 Titre : Cybervictimization in adolescence and its association with subsequent suicidal ideation/attempt beyond face-to-face victimization: a longitudinal population-based study Type de document : Texte imprimé et/ou numérique Auteurs : Léa C. PERRET, Auteur ; Massimiliano ORRI, Auteur ; Michel BOIVIN, Auteur ; Isabelle OUELLET-MORIN, Auteur ; Anne-Sophie DENAULT, Auteur ; Sylvana M. CÔTÉ, Auteur ; Richard E. TREMBLAY, Auteur ; Johanne RENAUD, Auteur ; Gustavo TURECKI, Auteur ; Marie-Claude GEOFFROY, Auteur Article en page(s) : p.866-874 Langues : Anglais (eng) Mots-clés : Adolescence  Quebec Longitudinal Study of Child Development  longitudinal cohort  suicidal ideation  suicide attempt Index. décimale : PER Périodiques Résumé : BACKGROUND: Cross-sectional associations have been documented between cybervictimization and suicidal risk; however, prospective associations remain unclear. METHODS: Participants were members of the Quebec Longitudinal Study of Child Development (QLSCD), a prospective birth cohort of 2,120 individuals followed from birth (1997/98) to age 17 years (2014/15). Cybervictimization and face-to-face victimization experienced since the beginning of the school year, as well as serious suicidal ideation and/or suicide attempt were self-reported at ages 13, 15 and 17 years. RESULTS: In cross-sectional analyses at 13, 15 and 17 years, adolescents cybervictimized at least once had, respectively, 2.3 (95% CI = 1.64-3.19), 4.2 (95% CI = 3.27-5.41) and 3.5 (95% CI = 2.57-4.66) higher odds of suicidal ideation/attempt after adjusting for confounders including face-to-face victimization, prior mental health symptoms and family hardship. Sensitivity analyses suggested that cybervictimization only and both cyber- and face-to-face victimization were associated with a higher risk of suicidal ideation/attempt compared to face-to-face victimization only and no victimization; however, analyses were based on small n. In prospective analyses, cybervictimization was not associated with suicidal ideation/attempt 2 years later after accounting for baseline suicidal ideation/attempt and other confounders. In contrast, face-to-face victimization was associated with suicidal ideation/attempt 2 years later in the fully adjusted model, including cybervictimization. CONCLUSIONS: The cross-sectional association between cybervictimization and suicidal ideation/attempt is independent from face-to-face victimization. The absence of a prospective association suggested short-term effects of cybervictimization on suicidal ideation/attempt. En ligne : http://dx.doi.org/10.1111/jcpp.13158 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429 [article] Cybervictimization in adolescence and its association with subsequent suicidal ideation/attempt beyond face-to-face victimization: a longitudinal population-based study [Texte imprimé et/ou numérique] / Léa C. PERRET, Auteur ; Massimiliano ORRI, Auteur ; Michel BOIVIN, Auteur ; Isabelle OUELLET-MORIN, Auteur ; Anne-Sophie DENAULT, Auteur ; Sylvana M. CÔTÉ, Auteur ; Richard E. TREMBLAY, Auteur ; Johanne RENAUD, Auteur ; Gustavo TURECKI, Auteur ; Marie-Claude GEOFFROY, Auteur . - p.866-874. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 61-8 (August 2020) . - p.866-874 Mots-clés : Adolescence  Quebec Longitudinal Study of Child Development  longitudinal cohort  suicidal ideation  suicide attempt Index. décimale : PER Périodiques Résumé : BACKGROUND: Cross-sectional associations have been documented between cybervictimization and suicidal risk; however, prospective associations remain unclear. METHODS: Participants were members of the Quebec Longitudinal Study of Child Development (QLSCD), a prospective birth cohort of 2,120 individuals followed from birth (1997/98) to age 17 years (2014/15). Cybervictimization and face-to-face victimization experienced since the beginning of the school year, as well as serious suicidal ideation and/or suicide attempt were self-reported at ages 13, 15 and 17 years. RESULTS: In cross-sectional analyses at 13, 15 and 17 years, adolescents cybervictimized at least once had, respectively, 2.3 (95% CI = 1.64-3.19), 4.2 (95% CI = 3.27-5.41) and 3.5 (95% CI = 2.57-4.66) higher odds of suicidal ideation/attempt after adjusting for confounders including face-to-face victimization, prior mental health symptoms and family hardship. Sensitivity analyses suggested that cybervictimization only and both cyber- and face-to-face victimization were associated with a higher risk of suicidal ideation/attempt compared to face-to-face victimization only and no victimization; however, analyses were based on small n. In prospective analyses, cybervictimization was not associated with suicidal ideation/attempt 2 years later after accounting for baseline suicidal ideation/attempt and other confounders. In contrast, face-to-face victimization was associated with suicidal ideation/attempt 2 years later in the fully adjusted model, including cybervictimization. CONCLUSIONS: The cross-sectional association between cybervictimization and suicidal ideation/attempt is independent from face-to-face victimization. The absence of a prospective association suggested short-term effects of cybervictimization on suicidal ideation/attempt. En ligne : http://dx.doi.org/10.1111/jcpp.13158 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429

Polygenic risk score and peer victimisation independently predict depressive symptoms in adolescence: results from the Quebec Longitudinal Study of Children Development / Léa C. PERRET in Journal of Child Psychology and Psychiatry, 64-3 (March 2023)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 64-3 (March 2023) . - p.388-396 Titre : Polygenic risk score and peer victimisation independently predict depressive symptoms in adolescence: results from the Quebec Longitudinal Study of Children Development Type de document : Texte imprimé et/ou numérique Auteurs : Léa C. PERRET, Auteur ; Michel BOIVIN, Auteur ; Geneviève MORNEAU-VAILLANCOURT, Auteur ; Till F. M. ANDLAUER, Auteur ; Stéphane PAQUIN, Auteur ; Stéphanie LANGEVIN, Auteur ; Alain GIRARD, Auteur ; Gustavo TURECKI, Auteur ; Kieran J. O'DONNELL, Auteur ; Richard E. TREMBLAY, Auteur ; Sylvana M. CÔTÉ, Auteur ; Jean-Philippe GOUIN, Auteur ; Isabelle OUELLET-MORIN, Auteur ; Marie-Claude GEOFFROY, Auteur Article en page(s) : p.388-396 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background Peer victimisation has been associated with depressive symptoms during adolescence, however not all peer victimised adolescents will exhibit such symptoms. This study tested whether having a genetic predisposition to developing depression increased the risk of experiencing depressive symptoms in peer victimised youth. To date, no study has explored such gene-environment interaction using a polygenic risk score for depression (PRS-depression) in the context of peer victimisation and depressive symptoms in adolescence. Methods The sample included 748 participants born in 1997/98 from the Quebec Longitudinal Study of Child Development with genotype data and prospectively collected information on peer victimisation (12-13 years) obtained from both self- and teacher-reports, as well as self-reported depressive symptoms (15-17 years). The PRS-depression was based on the genome-wide association meta-analysis of broad depression by Howard et al. (2019). Results Self- and teacher-reported peer victimisation in early adolescence were both associated with depressive symptoms in adolescence (Î2=0.34, p < .001; Î2=0.14, p=.001 respectively), and this association remained significant when accounting for PRS-depression (Î2=0.33, p < .001; Î2=0.13, p=.002 respectively). PRS-depression was independently associated with depressive symptoms, but there was no significant PRS-depression by peer victimisation interaction (self-reported and teacher-reported). PRS-depression was correlated with self-reported, but not teacher-reported, peer victimisation. Conclusions Our findings suggested that a partial measure of an individual's genetic predisposition to depression, as measured by PRS-depression, and being exposed to peer victimisation (self- and teacher-reported) were independently associated with depressive symptoms in adolescence. Furthermore, PRS-depression did not exacerbate the risk of depressive symptoms among adolescents who had been peer victimised. Lastly, we found evidence of a gene-environment correlation between PRS-depression and self-reported peer victimisation. Future studies are needed to replicate this finding and to further understand the role of genetic predispositions in experiencing depressive symptoms following peer victimisation. En ligne : https://doi.org/10.1111/jcpp.13706 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=493 [article] Polygenic risk score and peer victimisation independently predict depressive symptoms in adolescence: results from the Quebec Longitudinal Study of Children Development [Texte imprimé et/ou numérique] / Léa C. PERRET, Auteur ; Michel BOIVIN, Auteur ; Geneviève MORNEAU-VAILLANCOURT, Auteur ; Till F. M. ANDLAUER, Auteur ; Stéphane PAQUIN, Auteur ; Stéphanie LANGEVIN, Auteur ; Alain GIRARD, Auteur ; Gustavo TURECKI, Auteur ; Kieran J. O'DONNELL, Auteur ; Richard E. TREMBLAY, Auteur ; Sylvana M. CÔTÉ, Auteur ; Jean-Philippe GOUIN, Auteur ; Isabelle OUELLET-MORIN, Auteur ; Marie-Claude GEOFFROY, Auteur . - p.388-396. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 64-3 (March 2023) . - p.388-396 Index. décimale : PER Périodiques Résumé : Background Peer victimisation has been associated with depressive symptoms during adolescence, however not all peer victimised adolescents will exhibit such symptoms. This study tested whether having a genetic predisposition to developing depression increased the risk of experiencing depressive symptoms in peer victimised youth. To date, no study has explored such gene-environment interaction using a polygenic risk score for depression (PRS-depression) in the context of peer victimisation and depressive symptoms in adolescence. Methods The sample included 748 participants born in 1997/98 from the Quebec Longitudinal Study of Child Development with genotype data and prospectively collected information on peer victimisation (12-13 years) obtained from both self- and teacher-reports, as well as self-reported depressive symptoms (15-17 years). The PRS-depression was based on the genome-wide association meta-analysis of broad depression by Howard et al. (2019). Results Self- and teacher-reported peer victimisation in early adolescence were both associated with depressive symptoms in adolescence (Î2=0.34, p < .001; Î2=0.14, p=.001 respectively), and this association remained significant when accounting for PRS-depression (Î2=0.33, p < .001; Î2=0.13, p=.002 respectively). PRS-depression was independently associated with depressive symptoms, but there was no significant PRS-depression by peer victimisation interaction (self-reported and teacher-reported). PRS-depression was correlated with self-reported, but not teacher-reported, peer victimisation. Conclusions Our findings suggested that a partial measure of an individual's genetic predisposition to depression, as measured by PRS-depression, and being exposed to peer victimisation (self- and teacher-reported) were independently associated with depressive symptoms in adolescence. Furthermore, PRS-depression did not exacerbate the risk of depressive symptoms among adolescents who had been peer victimised. Lastly, we found evidence of a gene-environment correlation between PRS-depression and self-reported peer victimisation. Future studies are needed to replicate this finding and to further understand the role of genetic predispositions in experiencing depressive symptoms following peer victimisation. En ligne : https://doi.org/10.1111/jcpp.13706 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=493

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