Contribution of genes and environment to the longitudinal association between childhood impulsive-aggression and suicidality in adolescence / Massimiliano ORRI in Journal of Child Psychology and Psychiatry, 61-6 (June 2020)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 61-6 (June 2020) . - p.711-720 Titre : Contribution of genes and environment to the longitudinal association between childhood impulsive-aggression and suicidality in adolescence Type de document : Texte imprimé et/ou numérique Auteurs : Massimiliano ORRI, Auteur ; Marie-Claude GEOFFROY, Auteur ; Gustavo TURECKI, Auteur ; Bei FENG, Auteur ; Mara BRENDGEN, Auteur ; Frank VITARO, Auteur ; Ginette DIONNE, Auteur ; Stéphane PAQUIN, Auteur ; Cédric GALERA, Auteur ; Johanne RENAUD, Auteur ; Richard E. TREMBLAY, Auteur ; Sylvana M. CÔTÉ, Auteur ; Michel BOIVIN, Auteur Article en page(s) : p.711-720 Langues : Anglais (eng) Mots-clés : Suicide attempt  behavioral genetics  impulsive-aggression  longitudinal  suicidal ideation  twin study Index. décimale : PER Périodiques Résumé : BACKGROUND: Population-based and family studies showed that impulsive-aggression predicts suicidality; however, the underlying etiological nature of this association is poorly understood. The objective was to determine the contribution of genes and environment to the association between childhood impulsive-aggression and serious suicidal ideation/attempt in young adulthood. METHODS: N = 862 twins (435 families) from the Quebec Newborn Twin Study were followed up from birth to 20 years. Repeated measures of teacher-assessed impulsive-aggression were modeled using a genetically informed latent growth model including intercept and slope parameters reflecting individual differences in the baseline level (age 6 years) and in the change (increase/decrease) of impulsive-aggression during childhood (6 to 12 years), respectively. Lifetime suicidality (serious suicidal ideation/attempt) was self-reported at 20 years. Associations of impulsive-aggression intercept and slope with suicidality were decomposed into additive genetic (A) and unique environmental (E) components. RESULTS: Additive genetic factors accounted for an important part of individual differences in impulsive-aggression intercept (A = 90%, E = 10%) and slope (A = 65%, E = 35%). Genetic (50%) and unique environmental (50%) factors equally contributed to suicidality. We found that 38% of the genetic factors accounting for suicidality were shared with those underlying impulsive-aggression slope, whereas 40% of the environmental factors accounting for suicidality were shared with those associated with impulsive-aggression intercept. The genetic correlation between impulsive-aggression slope and suicidality was 0.60, p = .027. CONCLUSIONS: Genetic and unique environmental factors underlying suicidality significantly overlap with those underlying childhood impulsive-aggression. Future studies should identify putative genetic and environmental factors to inform prevention. En ligne : http://dx.doi.org/10.1111/jcpp.13163 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=426 [article] Contribution of genes and environment to the longitudinal association between childhood impulsive-aggression and suicidality in adolescence [Texte imprimé et/ou numérique] / Massimiliano ORRI, Auteur ; Marie-Claude GEOFFROY, Auteur ; Gustavo TURECKI, Auteur ; Bei FENG, Auteur ; Mara BRENDGEN, Auteur ; Frank VITARO, Auteur ; Ginette DIONNE, Auteur ; Stéphane PAQUIN, Auteur ; Cédric GALERA, Auteur ; Johanne RENAUD, Auteur ; Richard E. TREMBLAY, Auteur ; Sylvana M. CÔTÉ, Auteur ; Michel BOIVIN, Auteur . - p.711-720. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 61-6 (June 2020) . - p.711-720 Mots-clés : Suicide attempt  behavioral genetics  impulsive-aggression  longitudinal  suicidal ideation  twin study Index. décimale : PER Périodiques Résumé : BACKGROUND: Population-based and family studies showed that impulsive-aggression predicts suicidality; however, the underlying etiological nature of this association is poorly understood. The objective was to determine the contribution of genes and environment to the association between childhood impulsive-aggression and serious suicidal ideation/attempt in young adulthood. METHODS: N = 862 twins (435 families) from the Quebec Newborn Twin Study were followed up from birth to 20 years. Repeated measures of teacher-assessed impulsive-aggression were modeled using a genetically informed latent growth model including intercept and slope parameters reflecting individual differences in the baseline level (age 6 years) and in the change (increase/decrease) of impulsive-aggression during childhood (6 to 12 years), respectively. Lifetime suicidality (serious suicidal ideation/attempt) was self-reported at 20 years. Associations of impulsive-aggression intercept and slope with suicidality were decomposed into additive genetic (A) and unique environmental (E) components. RESULTS: Additive genetic factors accounted for an important part of individual differences in impulsive-aggression intercept (A = 90%, E = 10%) and slope (A = 65%, E = 35%). Genetic (50%) and unique environmental (50%) factors equally contributed to suicidality. We found that 38% of the genetic factors accounting for suicidality were shared with those underlying impulsive-aggression slope, whereas 40% of the environmental factors accounting for suicidality were shared with those associated with impulsive-aggression intercept. The genetic correlation between impulsive-aggression slope and suicidality was 0.60, p = .027. CONCLUSIONS: Genetic and unique environmental factors underlying suicidality significantly overlap with those underlying childhood impulsive-aggression. Future studies should identify putative genetic and environmental factors to inform prevention. En ligne : http://dx.doi.org/10.1111/jcpp.13163 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=426

Cybervictimization in adolescence and its association with subsequent suicidal ideation/attempt beyond face-to-face victimization: a longitudinal population-based study / Léa C. PERRET in Journal of Child Psychology and Psychiatry, 61-8 (August 2020)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 61-8 (August 2020) . - p.866-874 Titre : Cybervictimization in adolescence and its association with subsequent suicidal ideation/attempt beyond face-to-face victimization: a longitudinal population-based study Type de document : Texte imprimé et/ou numérique Auteurs : Léa C. PERRET, Auteur ; Massimiliano ORRI, Auteur ; Michel BOIVIN, Auteur ; Isabelle OUELLET-MORIN, Auteur ; Anne-Sophie DENAULT, Auteur ; Sylvana M. CÔTÉ, Auteur ; Richard E. TREMBLAY, Auteur ; Johanne RENAUD, Auteur ; Gustavo TURECKI, Auteur ; Marie-Claude GEOFFROY, Auteur Article en page(s) : p.866-874 Langues : Anglais (eng) Mots-clés : Adolescence  Quebec Longitudinal Study of Child Development  longitudinal cohort  suicidal ideation  suicide attempt Index. décimale : PER Périodiques Résumé : BACKGROUND: Cross-sectional associations have been documented between cybervictimization and suicidal risk; however, prospective associations remain unclear. METHODS: Participants were members of the Quebec Longitudinal Study of Child Development (QLSCD), a prospective birth cohort of 2,120 individuals followed from birth (1997/98) to age 17 years (2014/15). Cybervictimization and face-to-face victimization experienced since the beginning of the school year, as well as serious suicidal ideation and/or suicide attempt were self-reported at ages 13, 15 and 17 years. RESULTS: In cross-sectional analyses at 13, 15 and 17 years, adolescents cybervictimized at least once had, respectively, 2.3 (95% CI = 1.64-3.19), 4.2 (95% CI = 3.27-5.41) and 3.5 (95% CI = 2.57-4.66) higher odds of suicidal ideation/attempt after adjusting for confounders including face-to-face victimization, prior mental health symptoms and family hardship. Sensitivity analyses suggested that cybervictimization only and both cyber- and face-to-face victimization were associated with a higher risk of suicidal ideation/attempt compared to face-to-face victimization only and no victimization; however, analyses were based on small n. In prospective analyses, cybervictimization was not associated with suicidal ideation/attempt 2 years later after accounting for baseline suicidal ideation/attempt and other confounders. In contrast, face-to-face victimization was associated with suicidal ideation/attempt 2 years later in the fully adjusted model, including cybervictimization. CONCLUSIONS: The cross-sectional association between cybervictimization and suicidal ideation/attempt is independent from face-to-face victimization. The absence of a prospective association suggested short-term effects of cybervictimization on suicidal ideation/attempt. En ligne : http://dx.doi.org/10.1111/jcpp.13158 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429 [article] Cybervictimization in adolescence and its association with subsequent suicidal ideation/attempt beyond face-to-face victimization: a longitudinal population-based study [Texte imprimé et/ou numérique] / Léa C. PERRET, Auteur ; Massimiliano ORRI, Auteur ; Michel BOIVIN, Auteur ; Isabelle OUELLET-MORIN, Auteur ; Anne-Sophie DENAULT, Auteur ; Sylvana M. CÔTÉ, Auteur ; Richard E. TREMBLAY, Auteur ; Johanne RENAUD, Auteur ; Gustavo TURECKI, Auteur ; Marie-Claude GEOFFROY, Auteur . - p.866-874. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 61-8 (August 2020) . - p.866-874 Mots-clés : Adolescence  Quebec Longitudinal Study of Child Development  longitudinal cohort  suicidal ideation  suicide attempt Index. décimale : PER Périodiques Résumé : BACKGROUND: Cross-sectional associations have been documented between cybervictimization and suicidal risk; however, prospective associations remain unclear. METHODS: Participants were members of the Quebec Longitudinal Study of Child Development (QLSCD), a prospective birth cohort of 2,120 individuals followed from birth (1997/98) to age 17 years (2014/15). Cybervictimization and face-to-face victimization experienced since the beginning of the school year, as well as serious suicidal ideation and/or suicide attempt were self-reported at ages 13, 15 and 17 years. RESULTS: In cross-sectional analyses at 13, 15 and 17 years, adolescents cybervictimized at least once had, respectively, 2.3 (95% CI = 1.64-3.19), 4.2 (95% CI = 3.27-5.41) and 3.5 (95% CI = 2.57-4.66) higher odds of suicidal ideation/attempt after adjusting for confounders including face-to-face victimization, prior mental health symptoms and family hardship. Sensitivity analyses suggested that cybervictimization only and both cyber- and face-to-face victimization were associated with a higher risk of suicidal ideation/attempt compared to face-to-face victimization only and no victimization; however, analyses were based on small n. In prospective analyses, cybervictimization was not associated with suicidal ideation/attempt 2 years later after accounting for baseline suicidal ideation/attempt and other confounders. In contrast, face-to-face victimization was associated with suicidal ideation/attempt 2 years later in the fully adjusted model, including cybervictimization. CONCLUSIONS: The cross-sectional association between cybervictimization and suicidal ideation/attempt is independent from face-to-face victimization. The absence of a prospective association suggested short-term effects of cybervictimization on suicidal ideation/attempt. En ligne : http://dx.doi.org/10.1111/jcpp.13158 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429

Developmental profiles of childhood attention-deficit/hyperactivity disorder and irritability: association with adolescent mental health, functional impairment, and suicidal outcomes / Cédric GALERA in Journal of Child Psychology and Psychiatry, 62-2 (February 2021)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 62-2 (February 2021) . - p.232-243 Titre : Developmental profiles of childhood attention-deficit/hyperactivity disorder and irritability: association with adolescent mental health, functional impairment, and suicidal outcomes Type de document : Texte imprimé et/ou numérique Auteurs : Cédric GALERA, Auteur ; Massimiliano ORRI, Auteur ; Francis VERGUNST, Auteur ; Maria MELCHIOR, Auteur ; Judith VAN DER WAERDEN, Auteur ; Manuel P. BOUVARD, Auteur ; Ophélie COLLET, Auteur ; Michel BOIVIN, Auteur ; Richard E. TREMBLAY, Auteur ; Sylvana M. CÔTÉ, Auteur Année de publication : 2021 Article en page(s) : p.232-243 Langues : Anglais (eng) Mots-clés : Adhd  functional impairment  irritability  mental health problems  suicide Index. décimale : PER Périodiques Résumé : BACKGROUND: Irritability is frequently comorbid with ADHD. Although irritability alone has been linked to deleterious mental health and adaptive issues, the joint developmental course of ADHD and irritability symptoms during childhood as well as its association with later mental health and suicidal outcomes is not fully understood. We aimed to describe the developmental trajectories of childhood ADHD and irritability symptoms and to quantify their association with adolescent mental health and suicidal outcomes. METHODS: The Quebec Longitudinal Study of Child Development (QLSCD) included 1407 participants from the general population followed up from age 5 months to 17 years. We used a multitrajectory approach to identify developmental trajectories of childhood (6-12 years) ADHD and irritability symptoms. Outcome measures were adolescent (13-17 years) mental health (psychiatric symptoms/functional impairment) and suicidal outcomes. RESULTS: We identified distinct developmental profiles: combined absent or very low ADHD and absent or very low irritability (940 [66.8%]; reference group), moderately high irritability and low ADHD (158 [11.2%]), moderately high ADHD and low irritability (198 [14.1%]), and combined high ADHD and high irritability (111 [7.9%]). Multivariate modeling showed that, compared to children in the reference group, those in the combined high ADHD and high irritability profile showed higher levels of ADHD continuity (d ranges = 0.40-0.50), externalizing (d ranges = 0.25-0.59), internalizing (d ranges = 0.20-0.29), and functional impairments (d ranges = 0.17-0.48) and suicidal behaviors (odds ratio (OR) = 2.12, confidence interval (CI) = 1.47-3.06) in adolescence. CONCLUSIONS: The presence of persistently high levels of irritability along with ADHD symptoms during childhood significantly predicts adolescent ADHD continuity, externalizing, internalizing, and suicidal outcomes. Systematic consideration of irritability when assessing and treating ADHD may improve long-term mental health outcomes. En ligne : http://dx.doi.org/10.1111/jcpp.13270 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=440 [article] Developmental profiles of childhood attention-deficit/hyperactivity disorder and irritability: association with adolescent mental health, functional impairment, and suicidal outcomes [Texte imprimé et/ou numérique] / Cédric GALERA, Auteur ; Massimiliano ORRI, Auteur ; Francis VERGUNST, Auteur ; Maria MELCHIOR, Auteur ; Judith VAN DER WAERDEN, Auteur ; Manuel P. BOUVARD, Auteur ; Ophélie COLLET, Auteur ; Michel BOIVIN, Auteur ; Richard E. TREMBLAY, Auteur ; Sylvana M. CÔTÉ, Auteur . - 2021 . - p.232-243. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 62-2 (February 2021) . - p.232-243 Mots-clés : Adhd  functional impairment  irritability  mental health problems  suicide Index. décimale : PER Périodiques Résumé : BACKGROUND: Irritability is frequently comorbid with ADHD. Although irritability alone has been linked to deleterious mental health and adaptive issues, the joint developmental course of ADHD and irritability symptoms during childhood as well as its association with later mental health and suicidal outcomes is not fully understood. We aimed to describe the developmental trajectories of childhood ADHD and irritability symptoms and to quantify their association with adolescent mental health and suicidal outcomes. METHODS: The Quebec Longitudinal Study of Child Development (QLSCD) included 1407 participants from the general population followed up from age 5 months to 17 years. We used a multitrajectory approach to identify developmental trajectories of childhood (6-12 years) ADHD and irritability symptoms. Outcome measures were adolescent (13-17 years) mental health (psychiatric symptoms/functional impairment) and suicidal outcomes. RESULTS: We identified distinct developmental profiles: combined absent or very low ADHD and absent or very low irritability (940 [66.8%]; reference group), moderately high irritability and low ADHD (158 [11.2%]), moderately high ADHD and low irritability (198 [14.1%]), and combined high ADHD and high irritability (111 [7.9%]). Multivariate modeling showed that, compared to children in the reference group, those in the combined high ADHD and high irritability profile showed higher levels of ADHD continuity (d ranges = 0.40-0.50), externalizing (d ranges = 0.25-0.59), internalizing (d ranges = 0.20-0.29), and functional impairments (d ranges = 0.17-0.48) and suicidal behaviors (odds ratio (OR) = 2.12, confidence interval (CI) = 1.47-3.06) in adolescence. CONCLUSIONS: The presence of persistently high levels of irritability along with ADHD symptoms during childhood significantly predicts adolescent ADHD continuity, externalizing, internalizing, and suicidal outcomes. Systematic consideration of irritability when assessing and treating ADHD may improve long-term mental health outcomes. En ligne : http://dx.doi.org/10.1111/jcpp.13270 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=440

Maternal depression symptoms, child behavior problems, and their transactional relations: Probing the role of formal childcare / Chantal PAQUIN in Development and Psychopathology, 32-3 (August 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-3 (August 2020) . - p.831-844 Titre : Maternal depression symptoms, child behavior problems, and their transactional relations: Probing the role of formal childcare Type de document : Texte imprimé et/ou numérique Auteurs : Chantal PAQUIN, Auteur ; Natalie CASTELLANOS-RYAN, Auteur ; Frank VITARO, Auteur ; Sylvana M. CÔTÉ, Auteur ; Richard E. TREMBLAY, Auteur ; Jean R. SEGUIN, Auteur ; Michel BOIVIN, Auteur ; Catherine M. HERBA, Auteur Article en page(s) : p.831-844 Langues : Anglais (eng) Mots-clés : childcare, child development  externalizing problems  internalizing problems  maternal depressive symptoms Index. décimale : PER Périodiques Résumé : Among children exposed to elevated maternal depression symptoms (MDS), recent studies have demonstrated reduced internalizing and externalizing problems for those who have attended formal childcare (i.e., center-based, family-based childcare). However, these studies did not consider whether childcare attendance is associated with benefits for the child only or also with reduced MDS. Using a four-wave longitudinal cross-lagged model, we evaluated whether formal childcare attendance was associated with MDS or child behavior problems and whether it moderated longitudinal associations between MDS and child behavior problems and between child behavior problems and MDS. The sample was drawn from a population-based cohort study and consisted of 908 biologically related mother-child dyads, followed from 5 months to 5 years. Attending formal childcare was not associated with MDS or child behavior problems but moderated the association between MDS at 3.5 years and child internalizing and externalizing problems at 5 years as well as between girls' externalizing problems at 3.5 years and MDS at 5 years. No other moderation of formal childcare was found. Findings suggest that attending formal childcare reduces the risks of behavior problems in the context of MDS but also the risk of MDS in the context of girls' externalizing problems. En ligne : http://dx.doi.org/10.1017/s0954579419000956 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429 [article] Maternal depression symptoms, child behavior problems, and their transactional relations: Probing the role of formal childcare [Texte imprimé et/ou numérique] / Chantal PAQUIN, Auteur ; Natalie CASTELLANOS-RYAN, Auteur ; Frank VITARO, Auteur ; Sylvana M. CÔTÉ, Auteur ; Richard E. TREMBLAY, Auteur ; Jean R. SEGUIN, Auteur ; Michel BOIVIN, Auteur ; Catherine M. HERBA, Auteur . - p.831-844. Langues : Anglais (eng) in Development and Psychopathology > 32-3 (August 2020) . - p.831-844 Mots-clés : childcare, child development  externalizing problems  internalizing problems  maternal depressive symptoms Index. décimale : PER Périodiques Résumé : Among children exposed to elevated maternal depression symptoms (MDS), recent studies have demonstrated reduced internalizing and externalizing problems for those who have attended formal childcare (i.e., center-based, family-based childcare). However, these studies did not consider whether childcare attendance is associated with benefits for the child only or also with reduced MDS. Using a four-wave longitudinal cross-lagged model, we evaluated whether formal childcare attendance was associated with MDS or child behavior problems and whether it moderated longitudinal associations between MDS and child behavior problems and between child behavior problems and MDS. The sample was drawn from a population-based cohort study and consisted of 908 biologically related mother-child dyads, followed from 5 months to 5 years. Attending formal childcare was not associated with MDS or child behavior problems but moderated the association between MDS at 3.5 years and child internalizing and externalizing problems at 5 years as well as between girls' externalizing problems at 3.5 years and MDS at 5 years. No other moderation of formal childcare was found. Findings suggest that attending formal childcare reduces the risks of behavior problems in the context of MDS but also the risk of MDS in the context of girls' externalizing problems. En ligne : http://dx.doi.org/10.1017/s0954579419000956 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429

Moderation of parenting by inhibitory control in the prediction of the common and unique variance of hyperactivity-impulsivity and inattention / Charlie RIOUX in Development and Psychopathology, 32-3 (August 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-3 (August 2020) . - p.909-921 Titre : Moderation of parenting by inhibitory control in the prediction of the common and unique variance of hyperactivity-impulsivity and inattention Type de document : Texte imprimé et/ou numérique Auteurs : Charlie RIOUX, Auteur ; Julie MURRAY, Auteur ; Natalie CASTELLANOS-RYAN, Auteur ; Jean R. SEGUIN, Auteur ; Richard E. TREMBLAY, Auteur ; Sophie PARENT, Auteur Article en page(s) : p.909-921 Langues : Anglais (eng) Mots-clés : attention-deficit/hyperactivity disorder  effortful control  moderation  parenting  temperament Index. décimale : PER Périodiques Résumé : This study examined whether the interaction between parenting and inhibitory control predicts hyperactivity-impulsivity and inattention in 195 children. Observation data of positive parenting were collected at 4 years, and mother reports of coercive parenting at 5 years, inhibitory control at 6 years, and hyperactivity-impulsivity/inattention at 7 years were obtained. The common and unique variance of hyperactivity-impulsivity and inattention symptoms were examined as outcomes using a bifactor model. Results indicated that positive parenting practices predicted lower levels of hyperactivity-impulsivity/inattention behaviors at age 7 only when children's inhibitory control was high. These results support the vantage sensitivity model, which posits that some individuals show an increased sensitivity to positive experiences exclusively, and support the appropriateness of a targeted prevention approach in early childhood. En ligne : http://dx.doi.org/10.1017/s0954579419000774 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429 [article] Moderation of parenting by inhibitory control in the prediction of the common and unique variance of hyperactivity-impulsivity and inattention [Texte imprimé et/ou numérique] / Charlie RIOUX, Auteur ; Julie MURRAY, Auteur ; Natalie CASTELLANOS-RYAN, Auteur ; Jean R. SEGUIN, Auteur ; Richard E. TREMBLAY, Auteur ; Sophie PARENT, Auteur . - p.909-921. Langues : Anglais (eng) in Development and Psychopathology > 32-3 (August 2020) . - p.909-921 Mots-clés : attention-deficit/hyperactivity disorder  effortful control  moderation  parenting  temperament Index. décimale : PER Périodiques Résumé : This study examined whether the interaction between parenting and inhibitory control predicts hyperactivity-impulsivity and inattention in 195 children. Observation data of positive parenting were collected at 4 years, and mother reports of coercive parenting at 5 years, inhibitory control at 6 years, and hyperactivity-impulsivity/inattention at 7 years were obtained. The common and unique variance of hyperactivity-impulsivity and inattention symptoms were examined as outcomes using a bifactor model. Results indicated that positive parenting practices predicted lower levels of hyperactivity-impulsivity/inattention behaviors at age 7 only when children's inhibitory control was high. These results support the vantage sensitivity model, which posits that some individuals show an increased sensitivity to positive experiences exclusively, and support the appropriateness of a targeted prevention approach in early childhood. En ligne : http://dx.doi.org/10.1017/s0954579419000774 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429

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