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Auteur Emily SIMONOFF |
Documents disponibles écrits par cet auteur (39)
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Dual Cognitive and Biological Correlates of Anxiety in Autism Spectrum Disorders / Matthew J. HOLLOCKS in Journal of Autism and Developmental Disorders, 46-10 (October 2016)
[article]
Titre : Dual Cognitive and Biological Correlates of Anxiety in Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Matthew J. HOLLOCKS, Auteur ; Andrew PICKLES, Auteur ; Patricia HOWLIN, Auteur ; Emily SIMONOFF, Auteur Article en page(s) : p.3295-3307 Langues : Anglais (eng) Mots-clés : Attention Comorbidity Cortisol Emotion Stress Index. décimale : PER Périodiques Résumé : Young people with autism spectrum disorder (ASD) have a high prevalence (~40 %) of anxiety disorders compared to their non-ASD peers. It is unclear whether cognitive and biological processes associated with anxiety in ASD are analogous to anxiety in typically developing (TD) populations. In this study 55 boys with ASD (34 with a co-occurring anxiety disorder, 21 without) and 28 male controls, aged 10–16 years and with a full-scale IQ ? 70, completed a series of clinical, cognitive (attention bias/interpretation bias) and biological measures (salivary cortisol/HR response to social stress) associated with anxiety in TD populations. Structural equation modelling was used to reveal that that both attentional biases and physiological responsiveness were significant, but unrelated, predictors of anxiety in ASD. En ligne : http://dx.doi.org/10.1007/s10803-016-2878-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=293
in Journal of Autism and Developmental Disorders > 46-10 (October 2016) . - p.3295-3307[article] Dual Cognitive and Biological Correlates of Anxiety in Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Matthew J. HOLLOCKS, Auteur ; Andrew PICKLES, Auteur ; Patricia HOWLIN, Auteur ; Emily SIMONOFF, Auteur . - p.3295-3307.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 46-10 (October 2016) . - p.3295-3307
Mots-clés : Attention Comorbidity Cortisol Emotion Stress Index. décimale : PER Périodiques Résumé : Young people with autism spectrum disorder (ASD) have a high prevalence (~40 %) of anxiety disorders compared to their non-ASD peers. It is unclear whether cognitive and biological processes associated with anxiety in ASD are analogous to anxiety in typically developing (TD) populations. In this study 55 boys with ASD (34 with a co-occurring anxiety disorder, 21 without) and 28 male controls, aged 10–16 years and with a full-scale IQ ? 70, completed a series of clinical, cognitive (attention bias/interpretation bias) and biological measures (salivary cortisol/HR response to social stress) associated with anxiety in TD populations. Structural equation modelling was used to reveal that that both attentional biases and physiological responsiveness were significant, but unrelated, predictors of anxiety in ASD. En ligne : http://dx.doi.org/10.1007/s10803-016-2878-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=293 Everyday Memory’ Impairments in Autism Spectrum Disorders / Catherine R. G. JONES in Journal of Autism and Developmental Disorders, 41-4 (April 2011)
[article]
Titre : Everyday Memory’ Impairments in Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Catherine R. G. JONES, Auteur ; Francesca HAPPE, Auteur ; Andrew PICKLES, Auteur ; Anita J.S. MARSDEN, Auteur ; Jenifer TREGAY, Auteur ; Gillian BAIRD, Auteur ; Emily SIMONOFF, Auteur ; Tony CHARMAN, Auteur Année de publication : 2011 Article en page(s) : p.455-464 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders Everyday memory Prospective memory Rivermead Behavioural Memory Test Children’s Auditory Verbal Learning Test-2 Index. décimale : PER Périodiques Résumé : ‘Everyday memory’ is conceptualised as memory within the context of day-to-day life and, despite its functional relevance, has been little studied in individuals with autism spectrum disorders (ASDs). In the first study of its kind, 94 adolescents with an ASD and 55 without an ASD completed measures of everyday memory from the Rivermead Behavioural Memory Test (RBMT) and a standard word recall task (Children’s Auditory Verbal Learning Test-2: CAVLT-2). The ASD group showed significant impairments on the RBMT, including in prospective memory, alongside impaired performance on the CAVLT-2. Social and communication ability was significantly associated with prospective remembering in an everyday memory context but not with the CAVLT-2. The complex nature of everyday memory and its relevance to ASD is discussed. En ligne : http://dx.doi.org/10.1007/s10803-010-1067-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=119
in Journal of Autism and Developmental Disorders > 41-4 (April 2011) . - p.455-464[article] Everyday Memory’ Impairments in Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Catherine R. G. JONES, Auteur ; Francesca HAPPE, Auteur ; Andrew PICKLES, Auteur ; Anita J.S. MARSDEN, Auteur ; Jenifer TREGAY, Auteur ; Gillian BAIRD, Auteur ; Emily SIMONOFF, Auteur ; Tony CHARMAN, Auteur . - 2011 . - p.455-464.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 41-4 (April 2011) . - p.455-464
Mots-clés : Autism spectrum disorders Everyday memory Prospective memory Rivermead Behavioural Memory Test Children’s Auditory Verbal Learning Test-2 Index. décimale : PER Périodiques Résumé : ‘Everyday memory’ is conceptualised as memory within the context of day-to-day life and, despite its functional relevance, has been little studied in individuals with autism spectrum disorders (ASDs). In the first study of its kind, 94 adolescents with an ASD and 55 without an ASD completed measures of everyday memory from the Rivermead Behavioural Memory Test (RBMT) and a standard word recall task (Children’s Auditory Verbal Learning Test-2: CAVLT-2). The ASD group showed significant impairments on the RBMT, including in prospective memory, alongside impaired performance on the CAVLT-2. Social and communication ability was significantly associated with prospective remembering in an everyday memory context but not with the CAVLT-2. The complex nature of everyday memory and its relevance to ASD is discussed. En ligne : http://dx.doi.org/10.1007/s10803-010-1067-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=119 Evidence for overlapping genetic influences on autistic and ADHD behaviours in a community twin sample / Angelica RONALD in Journal of Child Psychology and Psychiatry, 49-5 (May 2008)
[article]
Titre : Evidence for overlapping genetic influences on autistic and ADHD behaviours in a community twin sample Type de document : Texte imprimé et/ou numérique Auteurs : Angelica RONALD, Auteur ; Emily SIMONOFF, Auteur ; Philip ASHERSON, Auteur ; Jonna KUNTSI, Auteur ; Robert PLOMIN, Auteur Année de publication : 2008 Article en page(s) : p.535–542 Langues : Anglais (eng) Mots-clés : ADD/ADHD autistic-disorder comorbidity genetics twins Index. décimale : PER Périodiques Résumé : Background: High levels of clinical comorbidity have been reported between autistic spectrum disorders (ASD) and attention deficit hyperactivity disorder (ADHD). This study takes an individual differences approach to determine the degree of phenotypic and aetiological overlap between autistic traits and ADHD behaviours in the general population.
Methods: The Twins Early Development Study is a community sample born in England and Wales. Families with twins born in 1994–6 were invited to join; 6,771 families participated in the study when the twins were 8 years old. Parents completed the Childhood Asperger Syndrome Test and the Conners’ DSM-IV subscales. Teacher data were also collected on a sub-sample. High scores on the Conners’ subscales were used to identify possible ADHD cases. Potential ASD cases were interviewed using the Development and Well-Being Assessment. Multivariate structural equation model-fitting was employed, as well as DeFries Fulker extremes analysis and liability threshold model-fitting.
Results: Significant correlations were found between autistic and ADHD traits in the general population (.54 for parent data, .51 for teacher data). In the bivariate models, all genetic correlations were >.50, indicating a moderate degree of overlap in genetic influences on autistic and ADHD traits, both throughout the general population and at the quantitative extreme. This phenotypic and genetic overlap still held when sex, IQ and conduct problems were controlled for, for both parent and teacher data. There was also substantial overlap in suspected cases (41% of children who met criteria for an ASD had suspected ADHD; 22% with suspected ADHD met criteria for an ASD).
Conclusions: These results suggest there are some common genetic influences operating across autistic traits and ADHD behaviours throughout normal variation and at the extreme. This is relevant for molecular genetic research, as well as for psychiatrists and psychologists, who may have assumed these two sets of behaviours are independent.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01857.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386
in Journal of Child Psychology and Psychiatry > 49-5 (May 2008) . - p.535–542[article] Evidence for overlapping genetic influences on autistic and ADHD behaviours in a community twin sample [Texte imprimé et/ou numérique] / Angelica RONALD, Auteur ; Emily SIMONOFF, Auteur ; Philip ASHERSON, Auteur ; Jonna KUNTSI, Auteur ; Robert PLOMIN, Auteur . - 2008 . - p.535–542.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 49-5 (May 2008) . - p.535–542
Mots-clés : ADD/ADHD autistic-disorder comorbidity genetics twins Index. décimale : PER Périodiques Résumé : Background: High levels of clinical comorbidity have been reported between autistic spectrum disorders (ASD) and attention deficit hyperactivity disorder (ADHD). This study takes an individual differences approach to determine the degree of phenotypic and aetiological overlap between autistic traits and ADHD behaviours in the general population.
Methods: The Twins Early Development Study is a community sample born in England and Wales. Families with twins born in 1994–6 were invited to join; 6,771 families participated in the study when the twins were 8 years old. Parents completed the Childhood Asperger Syndrome Test and the Conners’ DSM-IV subscales. Teacher data were also collected on a sub-sample. High scores on the Conners’ subscales were used to identify possible ADHD cases. Potential ASD cases were interviewed using the Development and Well-Being Assessment. Multivariate structural equation model-fitting was employed, as well as DeFries Fulker extremes analysis and liability threshold model-fitting.
Results: Significant correlations were found between autistic and ADHD traits in the general population (.54 for parent data, .51 for teacher data). In the bivariate models, all genetic correlations were >.50, indicating a moderate degree of overlap in genetic influences on autistic and ADHD traits, both throughout the general population and at the quantitative extreme. This phenotypic and genetic overlap still held when sex, IQ and conduct problems were controlled for, for both parent and teacher data. There was also substantial overlap in suspected cases (41% of children who met criteria for an ASD had suspected ADHD; 22% with suspected ADHD met criteria for an ASD).
Conclusions: These results suggest there are some common genetic influences operating across autistic traits and ADHD behaviours throughout normal variation and at the extreme. This is relevant for molecular genetic research, as well as for psychiatrists and psychologists, who may have assumed these two sets of behaviours are independent.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01857.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386 Examining clinicians? concerns delivering telemental health interventions directly to autistic individuals during COVID-19 / Lucy ADAMS in Research in Autism Spectrum Disorders, 94 (June 2022)
[article]
Titre : Examining clinicians? concerns delivering telemental health interventions directly to autistic individuals during COVID-19 Type de document : Texte imprimé et/ou numérique Auteurs : Lucy ADAMS, Auteur ; Nicoletta ADAMO, Auteur ; Matthew J. HOLLOCKS, Auteur ; Lucia VALMAGGIA, Auteur ; Aylana BREWSTER, Auteur ; Jennifer WATSON, Auteur ; Maisie KRISSON, Auteur ; Emily SIMONOFF, Auteur Article en page(s) : 101956 Langues : Anglais (eng) Mots-clés : Telepsychiatry ASD Telehealth Mental health interventions Index. décimale : PER Périodiques Résumé : Background The COVID-19 pandemic necessitated the adoption of telemental health (TMH). Pre-pandemic, clinicians had voiced many TMH concerns, but these had not been investigated with respect to autism spectrum disorder (ASD) even with it being known that there are distinct ASD-associated challenges for in-person mental health interventions. Method A convenience sample of (n = 55) clinicians completed an online survey regarding their perspectives of adopting TMH interventions in ASD, with closed- and open-answered questions. Quantitative and qualitative data were analysed descriptively/inferentially and via Content Analysis, respectively. Results Multiple clinicians endorsed each TMH challenges/barrier previously identified as concerns in the non-ASD literature. However, overall levels of concern over challenges/barriers were low, and challenges were more likely to be predicted than experienced and considered to be case/presentation specific. Challenges that were considered ASD-specific included the exacerbation of those associated with in-person delivery in ASD, alongside difficulties with trust and appropriate remote social behaviour. On average, clinicians indicated a preference for 50% TMH interventions post-pandemic. Clinicians? perceived technological competence and extent of professional experience with ASD were not significantly associated with levels of concern, nor number of experienced challenges, with TMH interventions in ASD. Conclusion In support of the existing TMH literature, challenges/barriers were more likely to be predicted than experienced and were considered to be case/presentation-specific, though this may be more variable in ASD owing to the well-established marked heterogeneity in this population. Remote provision of interventions exacerbated in-person ASD-associated challenges, as predicted, but clinician-level factors appeared not to impact TMH perceptions. En ligne : https://doi.org/10.1016/j.rasd.2022.101956 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=476
in Research in Autism Spectrum Disorders > 94 (June 2022) . - 101956[article] Examining clinicians? concerns delivering telemental health interventions directly to autistic individuals during COVID-19 [Texte imprimé et/ou numérique] / Lucy ADAMS, Auteur ; Nicoletta ADAMO, Auteur ; Matthew J. HOLLOCKS, Auteur ; Lucia VALMAGGIA, Auteur ; Aylana BREWSTER, Auteur ; Jennifer WATSON, Auteur ; Maisie KRISSON, Auteur ; Emily SIMONOFF, Auteur . - 101956.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 94 (June 2022) . - 101956
Mots-clés : Telepsychiatry ASD Telehealth Mental health interventions Index. décimale : PER Périodiques Résumé : Background The COVID-19 pandemic necessitated the adoption of telemental health (TMH). Pre-pandemic, clinicians had voiced many TMH concerns, but these had not been investigated with respect to autism spectrum disorder (ASD) even with it being known that there are distinct ASD-associated challenges for in-person mental health interventions. Method A convenience sample of (n = 55) clinicians completed an online survey regarding their perspectives of adopting TMH interventions in ASD, with closed- and open-answered questions. Quantitative and qualitative data were analysed descriptively/inferentially and via Content Analysis, respectively. Results Multiple clinicians endorsed each TMH challenges/barrier previously identified as concerns in the non-ASD literature. However, overall levels of concern over challenges/barriers were low, and challenges were more likely to be predicted than experienced and considered to be case/presentation specific. Challenges that were considered ASD-specific included the exacerbation of those associated with in-person delivery in ASD, alongside difficulties with trust and appropriate remote social behaviour. On average, clinicians indicated a preference for 50% TMH interventions post-pandemic. Clinicians? perceived technological competence and extent of professional experience with ASD were not significantly associated with levels of concern, nor number of experienced challenges, with TMH interventions in ASD. Conclusion In support of the existing TMH literature, challenges/barriers were more likely to be predicted than experienced and were considered to be case/presentation-specific, though this may be more variable in ASD owing to the well-established marked heterogeneity in this population. Remote provision of interventions exacerbated in-person ASD-associated challenges, as predicted, but clinician-level factors appeared not to impact TMH perceptions. En ligne : https://doi.org/10.1016/j.rasd.2022.101956 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=476 Exploring the cognitive, emotional and sensory correlates of social anxiety in autistic and neurotypical adolescents / Hannah PICKARD in Journal of Child Psychology and Psychiatry, 61-12 (December 2020)
[article]
Titre : Exploring the cognitive, emotional and sensory correlates of social anxiety in autistic and neurotypical adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Hannah PICKARD, Auteur ; Colette HIRSCH, Auteur ; Emily SIMONOFF, Auteur ; Francesca HAPPE, Auteur Article en page(s) : p.1317-1327 Langues : Anglais (eng) Mots-clés : Autism adolescence cognition emotion social anxiety Index. décimale : PER Périodiques Résumé : BACKGROUND: Social anxiety is common in autistic adolescents. While emerging evidence indicates the importance of several mechanisms (including intolerance of uncertainty (IU), alexithymia and sensory processing) for maintaining anxiety, limited research has explored how these factors are associated with social anxiety in autistic adolescents. METHODS: We investigated whether IU, emotional and sensory processing are related to social anxiety in autistic and neurotypical adolescents, gathering experimental and questionnaire data from 61 autistic and 62 neurotypical 11- to 17-year-olds recruited to have similarly high levels of anxiety. RESULTS: In autistic and neurotypical adolescents matched for social anxiety, similar significant associations were observed between social anxiety and IU, alexithymia, maladaptive emotion regulation, sensory hypersensitivity and interoceptive sensibility. Taking a dimensional approach, we found that child- and parent-reported IU, alexithymia and sensory hypersensitivity mediated the relationship between autistic traits and social anxiety symptoms in the combined group of adolescents. CONCLUSIONS: Our findings indicate that similar correlates of social anxiety are evident in autistic and neurotypical youths experiencing social anxiety and further our understanding of mechanisms that may contribute towards social anxiety in both groups. En ligne : http://dx.doi.org/10.1111/jcpp.13214 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1317-1327[article] Exploring the cognitive, emotional and sensory correlates of social anxiety in autistic and neurotypical adolescents [Texte imprimé et/ou numérique] / Hannah PICKARD, Auteur ; Colette HIRSCH, Auteur ; Emily SIMONOFF, Auteur ; Francesca HAPPE, Auteur . - p.1317-1327.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1317-1327
Mots-clés : Autism adolescence cognition emotion social anxiety Index. décimale : PER Périodiques Résumé : BACKGROUND: Social anxiety is common in autistic adolescents. While emerging evidence indicates the importance of several mechanisms (including intolerance of uncertainty (IU), alexithymia and sensory processing) for maintaining anxiety, limited research has explored how these factors are associated with social anxiety in autistic adolescents. METHODS: We investigated whether IU, emotional and sensory processing are related to social anxiety in autistic and neurotypical adolescents, gathering experimental and questionnaire data from 61 autistic and 62 neurotypical 11- to 17-year-olds recruited to have similarly high levels of anxiety. RESULTS: In autistic and neurotypical adolescents matched for social anxiety, similar significant associations were observed between social anxiety and IU, alexithymia, maladaptive emotion regulation, sensory hypersensitivity and interoceptive sensibility. Taking a dimensional approach, we found that child- and parent-reported IU, alexithymia and sensory hypersensitivity mediated the relationship between autistic traits and social anxiety symptoms in the combined group of adolescents. CONCLUSIONS: Our findings indicate that similar correlates of social anxiety are evident in autistic and neurotypical youths experiencing social anxiety and further our understanding of mechanisms that may contribute towards social anxiety in both groups. En ligne : http://dx.doi.org/10.1111/jcpp.13214 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 Factors associated with mental health symptoms among UK autistic children and young people and their parents during the COVID-19 pandemic / Melanie PALMER in Autism, 27-7 (October 2023)
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