Approches pédagogiques / Marie-Aude PIOT

Public ISBD in Médecine et santé de l'adolescent / Priscille GERARDIN Titre : Approches pédagogiques Type de document : texte imprimé Auteurs : Marie-Aude PIOT, Auteur ; Bruno FALISSARD, Auteur Année de publication : 2019 Importance : p.453-454 Langues : Français (fre) Index. décimale : SCI-G SCI-G - Autres Domaines Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=423 in Médecine et santé de l'adolescent / Priscille GERARDIN Approches pédagogiques [texte imprimé] / Marie-Aude PIOT, Auteur ; Bruno FALISSARD, Auteur . - 2019 . - p.453-454. Langues : Français (fre) Index. décimale : SCI-G SCI-G - Autres Domaines Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=423

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Assess the Fidelity, Validity and Responsiveness of the Brief Observation of Social Communication Change (BOSCC) to Measure Changes in the Social Interactions of Preschool Children With Autism Spectrum Disorder / Agathe JAY in Autism, 30-7 (July 2026)  

Public ISBD [article]  inAutism > 30-7 (July 2026) . - p.1863-1878 Titre : Assess the Fidelity, Validity and Responsiveness of the Brief Observation of Social Communication Change (BOSCC) to Measure Changes in the Social Interactions of Preschool Children With Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Agathe JAY, Auteur ; Lucie JUREK, Auteur ; Riham HAMADEH, Auteur ; Marie-Joëlle OREVE, Auteur ; Carmen M. SCHRÖDER, Auteur ; Véronique DELVENNE, Auteur ; Sandrine SONIE, Auteur ; Bruno FALISSARD, Auteur ; Olivia FEBVEY-COMBES, Auteur ; Mario SPERANZA, Auteur ; Marie-Maude GEOFFRAY, Auteur ; null NULL, Auteur Article en page(s) : p.1863-1878 Langues : Anglais (eng) Mots-clés : assess  autism spectrum disorder  fidelity  responsiveness  validity Index. décimale : PER Périodiques Résumé : Accurately measuring changes in core autism symptoms following early intervention is challenging. The Brief Observation of Social Communication Change (BOSCC) is a promising tool for assessing social interactions in preschoolers with autism spectrum disorder (ASD). However, data on its responsiveness remain limited, warranting validation to support its use in evaluating treatment-related changes. This study aimed to assess the reliability, validity, and sensitivity to change of the BOSCC based on international recommendations from the COSMIN expert group. The BOSCC was rated using 414 video observations from a large multicenter randomized controlled trial including 177 preschoolers with ASD between 19 and 36 months. Videos were coded using the original BOSCC protocol by trained, blinded raters. Analyses addressed reliability, structural and convergent validity, and responsiveness over a 2-year follow-up. Interrater, intrarater, and test–retest reliability were consistently high, with good internal consistency (Cronbach’s α = 0.88–0.98). Factor analysis supported a three-factor structure. Convergent validity was modest with Autism Diagnostic Observation Scale (ADOS) change scores (r = 0.05–0.20) but stronger with global ratings of improvement on the Clinical Global Impression–Improvement (CGI-I; r = 0.40–0.60, p < 0.001). ROC analyses confirmed acceptable to good responsiveness when anchored to the CGI-I, but poor discrimination relative to the ADOS. The BOSCC is a reliable and responsive measure of change in preschoolers with ASD. Its naturalistic format supports its use as an outcome measure in early intervention trials. Establishing thresholds for clinically meaningful change will be a critical next step for both research and clinical practice.Lay Abstract Early intervention may improve social interaction and communication in young children with autism spectrum disorder (ASD). However, it is often difficult to measure changes in core autism symptoms over time. Many commonly used assessment tools were developed for diagnosis and are not always sensitive to treatment-related change. The Brief Observation of Social Communication Change (BOSCC) was specifically designed to address this gap by using short, naturalistic observations of children’s social communication. This study examined how well the BOSCC works as a tool to capture change. We assessed its reliability (whether it gives consistent results), validity (whether it measures what it is intended to measure), and responsiveness (whether it can detect change over time). The study included 414 video observations from a large multicenter randomized controlled trial involving 177 preschool children with ASD, aged 19–36 months, followed up for over a 2-year period. Videos were rated by trained, independent observers using the original BOSCC coding system. Results showed that BOSCC is a highly reliable measure, with strong agreement between different raters and good consistency over time. The structure of the scale was supported, and BOSCC scores were meaningfully related to clinicians’ overall judgments of improvement. In contrast, changes in BOSCC scores were less closely related to changes measured by standard diagnostic tools. Overall, these findings support the BOSCC as a useful and sensitive outcome measure for evaluating change in early autism interventions. Future research should define thresholds for clinically meaningful change to strengthen its use in research, clinical practice, and service evaluation. En ligne : https://dx.doi.org/10.1177/13623613261442618 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=590 [article] Assess the Fidelity, Validity and Responsiveness of the Brief Observation of Social Communication Change (BOSCC) to Measure Changes in the Social Interactions of Preschool Children With Autism Spectrum Disorder [texte imprimé] / Agathe JAY, Auteur ; Lucie JUREK, Auteur ; Riham HAMADEH, Auteur ; Marie-Joëlle OREVE, Auteur ; Carmen M. SCHRÖDER, Auteur ; Véronique DELVENNE, Auteur ; Sandrine SONIE, Auteur ; Bruno FALISSARD, Auteur ; Olivia FEBVEY-COMBES, Auteur ; Mario SPERANZA, Auteur ; Marie-Maude GEOFFRAY, Auteur ; null NULL, Auteur . - p.1863-1878. Langues : Anglais (eng) in Autism > 30-7 (July 2026) . - p.1863-1878 Mots-clés : assess  autism spectrum disorder  fidelity  responsiveness  validity Index. décimale : PER Périodiques Résumé : Accurately measuring changes in core autism symptoms following early intervention is challenging. The Brief Observation of Social Communication Change (BOSCC) is a promising tool for assessing social interactions in preschoolers with autism spectrum disorder (ASD). However, data on its responsiveness remain limited, warranting validation to support its use in evaluating treatment-related changes. This study aimed to assess the reliability, validity, and sensitivity to change of the BOSCC based on international recommendations from the COSMIN expert group. The BOSCC was rated using 414 video observations from a large multicenter randomized controlled trial including 177 preschoolers with ASD between 19 and 36 months. Videos were coded using the original BOSCC protocol by trained, blinded raters. Analyses addressed reliability, structural and convergent validity, and responsiveness over a 2-year follow-up. Interrater, intrarater, and test–retest reliability were consistently high, with good internal consistency (Cronbach’s α = 0.88–0.98). Factor analysis supported a three-factor structure. Convergent validity was modest with Autism Diagnostic Observation Scale (ADOS) change scores (r = 0.05–0.20) but stronger with global ratings of improvement on the Clinical Global Impression–Improvement (CGI-I; r = 0.40–0.60, p < 0.001). ROC analyses confirmed acceptable to good responsiveness when anchored to the CGI-I, but poor discrimination relative to the ADOS. The BOSCC is a reliable and responsive measure of change in preschoolers with ASD. Its naturalistic format supports its use as an outcome measure in early intervention trials. Establishing thresholds for clinically meaningful change will be a critical next step for both research and clinical practice.Lay Abstract Early intervention may improve social interaction and communication in young children with autism spectrum disorder (ASD). However, it is often difficult to measure changes in core autism symptoms over time. Many commonly used assessment tools were developed for diagnosis and are not always sensitive to treatment-related change. The Brief Observation of Social Communication Change (BOSCC) was specifically designed to address this gap by using short, naturalistic observations of children’s social communication. This study examined how well the BOSCC works as a tool to capture change. We assessed its reliability (whether it gives consistent results), validity (whether it measures what it is intended to measure), and responsiveness (whether it can detect change over time). The study included 414 video observations from a large multicenter randomized controlled trial involving 177 preschool children with ASD, aged 19–36 months, followed up for over a 2-year period. Videos were rated by trained, independent observers using the original BOSCC coding system. Results showed that BOSCC is a highly reliable measure, with strong agreement between different raters and good consistency over time. The structure of the scale was supported, and BOSCC scores were meaningfully related to clinicians’ overall judgments of improvement. In contrast, changes in BOSCC scores were less closely related to changes measured by standard diagnostic tools. Overall, these findings support the BOSCC as a useful and sensitive outcome measure for evaluating change in early autism interventions. Future research should define thresholds for clinically meaningful change to strengthen its use in research, clinical practice, and service evaluation. En ligne : https://dx.doi.org/10.1177/13623613261442618 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=590

Bumetanide Oral Liquid Formulation for the Treatment of Children and Adolescents with Autism Spectrum Disorder: Design of Two Phase III Studies (SIGN Trials) / Véronique CRUTEL in Journal of Autism and Developmental Disorders, 51-8 (August 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-8 (August 2021) . - p.2959-2972 Titre : Bumetanide Oral Liquid Formulation for the Treatment of Children and Adolescents with Autism Spectrum Disorder: Design of Two Phase III Studies (SIGN Trials) Type de document : texte imprimé Auteurs : Véronique CRUTEL, Auteur ; Estelle LAMBERT, Auteur ; Pierre-François PÉNÉLAUD, Auteur ; Cristina ALBARRÁN SEVERO, Auteur ; Joaquin FUENTES, Auteur ; Antoine ROSIER, Auteur ; Amaia HERVAS, Auteur ; Stéphane MARRET, Auteur ; Guiomar OLIVEIRA, Auteur ; Mara PARELLADA, Auteur ; Simon KYAGA, Auteur ; Sylvie GOUTTEFANGEAS, Auteur ; Marianne BERTRAND, Auteur ; Denis RAVEL, Auteur ; Bruno FALISSARD, Auteur Article en page(s) : p.2959-2972 Langues : Anglais (eng) Mots-clés : Adolescent  Autism Spectrum Disorder/drug therapy  Bumetanide/administration & dosage/therapeutic use  Child  Child, Preschool  Double-Blind Method  Humans  Male  Research Design  Social Behavior  Treatment Outcome  Autism spectrum disorder  Bumetanide  Pediatrics  Randomized controlled trial  for Actelion, Allergan, Almirall, Astellas, AstraZeneca, Bayer, Biotronik, BMS,  Boehringer Ingelheim, Daiichi- Sankyo, Eli Lilly, Genzyme, Gilead, Grunenthal, GSK,  HRA, Janssen, Lundbeck, MSD, Novartis, Otsuka, Pierre Fabre, Roche, Sanofi, Servier,  Stallergene, UCB, ViiV. JF has received research support from Servier and  AIMS-2-Trials project ID 777394. DR is an employee of Neurochlore. GO, SM, AR, AH,  and MP report no conflict of interest. Index. décimale : PER Périodiques Résumé : There are currently no approved pharmacological treatments to improve social reciprocity and limit repetitive and rigid behaviors in autism spectrum disorder (ASD). We describe the design of two Phase III studies evaluating the efficacy/safety of bumetanide oral liquid formulation in ASD. These are international, multicenter, randomized, double-blind, placebo-controlled studies in children and adolescents with ASD aged 7 to 17 years (n = 200; study 1), or younger children with ASD aged 2 to 6 years (n = 200; study 2). The primary endpoint of each is change in Childhood Autism Rating Scale 2 total raw score after 6 months. These studies could contribute to the first pharmacological treatment to improve social reciprocity and limit repetitive and rigid behaviors in children and adolescents with ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04709-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453 [article] Bumetanide Oral Liquid Formulation for the Treatment of Children and Adolescents with Autism Spectrum Disorder: Design of Two Phase III Studies (SIGN Trials) [texte imprimé] / Véronique CRUTEL, Auteur ; Estelle LAMBERT, Auteur ; Pierre-François PÉNÉLAUD, Auteur ; Cristina ALBARRÁN SEVERO, Auteur ; Joaquin FUENTES, Auteur ; Antoine ROSIER, Auteur ; Amaia HERVAS, Auteur ; Stéphane MARRET, Auteur ; Guiomar OLIVEIRA, Auteur ; Mara PARELLADA, Auteur ; Simon KYAGA, Auteur ; Sylvie GOUTTEFANGEAS, Auteur ; Marianne BERTRAND, Auteur ; Denis RAVEL, Auteur ; Bruno FALISSARD, Auteur . - p.2959-2972. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-8 (August 2021) . - p.2959-2972 Mots-clés : Adolescent  Autism Spectrum Disorder/drug therapy  Bumetanide/administration & dosage/therapeutic use  Child  Child, Preschool  Double-Blind Method  Humans  Male  Research Design  Social Behavior  Treatment Outcome  Autism spectrum disorder  Bumetanide  Pediatrics  Randomized controlled trial  for Actelion, Allergan, Almirall, Astellas, AstraZeneca, Bayer, Biotronik, BMS,  Boehringer Ingelheim, Daiichi- Sankyo, Eli Lilly, Genzyme, Gilead, Grunenthal, GSK,  HRA, Janssen, Lundbeck, MSD, Novartis, Otsuka, Pierre Fabre, Roche, Sanofi, Servier,  Stallergene, UCB, ViiV. JF has received research support from Servier and  AIMS-2-Trials project ID 777394. DR is an employee of Neurochlore. GO, SM, AR, AH,  and MP report no conflict of interest. Index. décimale : PER Périodiques Résumé : There are currently no approved pharmacological treatments to improve social reciprocity and limit repetitive and rigid behaviors in autism spectrum disorder (ASD). We describe the design of two Phase III studies evaluating the efficacy/safety of bumetanide oral liquid formulation in ASD. These are international, multicenter, randomized, double-blind, placebo-controlled studies in children and adolescents with ASD aged 7 to 17 years (n = 200; study 1), or younger children with ASD aged 2 to 6 years (n = 200; study 2). The primary endpoint of each is change in Childhood Autism Rating Scale 2 total raw score after 6 months. These studies could contribute to the first pharmacological treatment to improve social reciprocity and limit repetitive and rigid behaviors in children and adolescents with ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04709-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453

Contribution à l’étude de la perception des formes géométriques, par comparaison des productions à la figure complexe de Rey d’enfants du Burkina Faso, d’Iran et de France / Muriel BOSSUROY in Approche Neuropsychologique des Apprentissages chez l'Enfant - A.N.A.E., 125 (Novembre 2013)

Public ISBD [article]  inApproche Neuropsychologique des Apprentissages chez l'Enfant - A.N.A.E. > 125 (Novembre 2013) . - p.438-445 Titre : Contribution à l’étude de la perception des formes géométriques, par comparaison des productions à la figure complexe de Rey d’enfants du Burkina Faso, d’Iran et de France Type de document : texte imprimé Auteurs : Muriel BOSSUROY, Auteur ; P. WALLON, Auteur ; Bruno FALISSARD, Auteur ; Marie-Rose MORO, Auteur Article en page(s) : p.438-445 Langues : Français (fre) Mots-clés : Culture  Perception  Tests non-verbaux  Cognition  Neuropsychologie  Figure de Rey et d’Osterrieth Index. décimale : PER Périodiques Résumé : Afin de mieux connaître les biais culturels dans les tests non-verbaux, nous testons l’hypothèse que l’environnement socioculturel a un impact sur la structuration perceptive de la figure complexe de Rey. Sont comparées les productions d’enfants scolarisés au Burkina Faso (n=76), en Iran (n=45) et en France (n=914) avec une cotation en types basée sur l’ordre de réalisation, et effectuée grâce à un enregistrement informatique du tracé. Les résultats montrent des contrastes importants entre les groupes, concernant tant les scores que les techniques de réalisation. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=226 [article] Contribution à l’étude de la perception des formes géométriques, par comparaison des productions à la figure complexe de Rey d’enfants du Burkina Faso, d’Iran et de France [texte imprimé] / Muriel BOSSUROY, Auteur ; P. WALLON, Auteur ; Bruno FALISSARD, Auteur ; Marie-Rose MORO, Auteur . - p.438-445. Langues : Français (fre) in Approche Neuropsychologique des Apprentissages chez l'Enfant - A.N.A.E. > 125 (Novembre 2013) . - p.438-445 Mots-clés : Culture  Perception  Tests non-verbaux  Cognition  Neuropsychologie  Figure de Rey et d’Osterrieth Index. décimale : PER Périodiques Résumé : Afin de mieux connaître les biais culturels dans les tests non-verbaux, nous testons l’hypothèse que l’environnement socioculturel a un impact sur la structuration perceptive de la figure complexe de Rey. Sont comparées les productions d’enfants scolarisés au Burkina Faso (n=76), en Iran (n=45) et en France (n=914) avec une cotation en types basée sur l’ordre de réalisation, et effectuée grâce à un enregistrement informatique du tracé. Les résultats montrent des contrastes importants entre les groupes, concernant tant les scores que les techniques de réalisation. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=226

Correction to: Bumetanide Oral Liquid Formulation for the Treatment of Children and Adolescents with Autism Spectrum Disorder: Design of Two Phase III Studies (SIGN Trials) / Véronique CRUTEL in Journal of Autism and Developmental Disorders, 51-8 (August 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-8 (August 2021) . - p.2973 Titre : Correction to: Bumetanide Oral Liquid Formulation for the Treatment of Children and Adolescents with Autism Spectrum Disorder: Design of Two Phase III Studies (SIGN Trials) Type de document : texte imprimé Auteurs : Véronique CRUTEL, Auteur ; Estelle LAMBERT, Auteur ; Pierre-François PÉNÉLAUD, Auteur ; Cristina ALBARRÁN SEVERO, Auteur ; Joaquin FUENTES, Auteur ; Antoine ROSIER, Auteur ; Amaia HERVAS, Auteur ; Stéphane MARRET, Auteur ; Guiomar OLIVEIRA, Auteur ; Mara PARELLADA, Auteur ; Simon KYAGA, Auteur ; Sylvie GOUTTEFANGEAS, Auteur ; Marianne BERTRAND, Auteur ; Denis RAVEL, Auteur ; Bruno FALISSARD, Auteur Article en page(s) : p.2973 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-020-04822-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453 [article] Correction to: Bumetanide Oral Liquid Formulation for the Treatment of Children and Adolescents with Autism Spectrum Disorder: Design of Two Phase III Studies (SIGN Trials) [texte imprimé] / Véronique CRUTEL, Auteur ; Estelle LAMBERT, Auteur ; Pierre-François PÉNÉLAUD, Auteur ; Cristina ALBARRÁN SEVERO, Auteur ; Joaquin FUENTES, Auteur ; Antoine ROSIER, Auteur ; Amaia HERVAS, Auteur ; Stéphane MARRET, Auteur ; Guiomar OLIVEIRA, Auteur ; Mara PARELLADA, Auteur ; Simon KYAGA, Auteur ; Sylvie GOUTTEFANGEAS, Auteur ; Marianne BERTRAND, Auteur ; Denis RAVEL, Auteur ; Bruno FALISSARD, Auteur . - p.2973. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-8 (August 2021) . - p.2973 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-020-04822-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453

Determinants of Inclusion in Mainstream School for Children with Autism Spectrum Disorders from the EpiTED Study: A 10-Year Follow-up Cohort / Charlotte LAFONT in Journal of Autism and Developmental Disorders, 53-1 (January 2023)  

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Un diagnostic délicat / Catherine VANIER in L'école des Parents, 619 (Avril-Mai-Juin 2016)

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Early childhood child care and disruptive behavior problems during adolescence: a 17-year population-based propensity score study / Massimiliano ORRI in Journal of Child Psychology and Psychiatry, 60-11 (November 2019)  

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Long-term follow-up of a randomized controlled trial comparing systemic family therapy (FT-S) added to treatment as usual (TAU) with TAU alone in adolescents with anorexia nervosa / Nathalie GODART in Journal of Child Psychology and Psychiatry, 63-11 (November 2022)  

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Mesure de la subjectivité / Bruno FALISSARD

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Méthodologie des essais thérapeutiques en psychiatrie / Bruno FALISSARD

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Méthodologie de l’évaluation des pratiques dans le champ de l’autisme / Bruno FALISSARD in Bulletin Scientifique de l'arapi (Le), 25 (Printemps 2010)

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Parent and professional perspectives on implementing the Pediatric Autism Communication Therapy: A mixed-methods analysis / Matea BALABANOVSKA in Autism, 29-1 (January 2025)  

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Parental experience of parent-mediated intervention for children with ASD: A systematic review and qualitative evidence synthesis / Lucie JUREK in Autism, 27-3 (April 2023)  

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A propos du dépistage précoce / Bruno FALISSARD in Enfance, 2009-1 (janvier-mars 2009)  

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