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Facial emotion training as an intervention in autism spectrum disorder: A meta-analysis of randomized controlled trials / Q. ZHANG in Autism Research, 14-10 (October 2021)
[article]
Titre : Facial emotion training as an intervention in autism spectrum disorder: A meta-analysis of randomized controlled trials Type de document : Texte imprimé et/ou numérique Auteurs : Q. ZHANG, Auteur ; R. WU, Auteur ; S. ZHU, Auteur ; J. LE, Auteur ; Y. CHEN, Auteur ; C. LAN, Auteur ; S. YAO, Auteur ; W. ZHAO, Auteur ; K. M. KENDRICK, Auteur Article en page(s) : p.2169-2182 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/therapy Emotions Facial Recognition Humans Randomized Controlled Trials as Topic Social Skills autism spectrum disorder emotion expression emotion recognition emotion understanding facial emotion training meta-analysis social skills Index. décimale : PER Périodiques Résumé : A large number of computer-based training programs have been developed as an intervention to help individuals with autism spectrum disorders (ASD) improve their facial emotion recognition ability, as well as social skills. However, it is unclear to what extent these facial emotion training programs can produce beneficial, long-lasting, and generalizable results. Using standard meta-analytic techniques, we investigated the effects of facial emotion training including generalization and maintenance restricted to randomized control trial studies comprising a total of 595 individuals with ASD. Our findings revealed that the intervention resulted in a robust improvement in emotion recognition for individuals receiving training compared with controls. However, while there was also some evidence for generalization of training effects, the small number of studies which conducted follow-ups and assessed social skills reported that improvements were not maintained and there was no evidence for general improvement in social skills. Overall, the analysis revealed a medium effect size in training improvement indicating that facial emotion training may be an effective method for enhancing emotion recognition skills in ASD although more studies are required to assess maintenance of effects and possible general improvements in social skills. LAY SUMMARY: Facial emotion training as an intervention may be a potential way to help improve emotion recognition in autism spectrum disorder (ASD), however robust empirical support for its efficacy has not been sufficiently established. Here, we conducted a meta-analysis of previous studies to summarize the effects of facial emotion training on ASD. Our results show that the training produces a robust improvement in subsequent emotion recognition, while maintenance and generalization effects still need further investigation. To date, no experimentally verified improvements in social skills have been reported. En ligne : http://dx.doi.org/10.1002/aur.2565 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450
in Autism Research > 14-10 (October 2021) . - p.2169-2182[article] Facial emotion training as an intervention in autism spectrum disorder: A meta-analysis of randomized controlled trials [Texte imprimé et/ou numérique] / Q. ZHANG, Auteur ; R. WU, Auteur ; S. ZHU, Auteur ; J. LE, Auteur ; Y. CHEN, Auteur ; C. LAN, Auteur ; S. YAO, Auteur ; W. ZHAO, Auteur ; K. M. KENDRICK, Auteur . - p.2169-2182.
Langues : Anglais (eng)
in Autism Research > 14-10 (October 2021) . - p.2169-2182
Mots-clés : Autism Spectrum Disorder/therapy Emotions Facial Recognition Humans Randomized Controlled Trials as Topic Social Skills autism spectrum disorder emotion expression emotion recognition emotion understanding facial emotion training meta-analysis social skills Index. décimale : PER Périodiques Résumé : A large number of computer-based training programs have been developed as an intervention to help individuals with autism spectrum disorders (ASD) improve their facial emotion recognition ability, as well as social skills. However, it is unclear to what extent these facial emotion training programs can produce beneficial, long-lasting, and generalizable results. Using standard meta-analytic techniques, we investigated the effects of facial emotion training including generalization and maintenance restricted to randomized control trial studies comprising a total of 595 individuals with ASD. Our findings revealed that the intervention resulted in a robust improvement in emotion recognition for individuals receiving training compared with controls. However, while there was also some evidence for generalization of training effects, the small number of studies which conducted follow-ups and assessed social skills reported that improvements were not maintained and there was no evidence for general improvement in social skills. Overall, the analysis revealed a medium effect size in training improvement indicating that facial emotion training may be an effective method for enhancing emotion recognition skills in ASD although more studies are required to assess maintenance of effects and possible general improvements in social skills. LAY SUMMARY: Facial emotion training as an intervention may be a potential way to help improve emotion recognition in autism spectrum disorder (ASD), however robust empirical support for its efficacy has not been sufficiently established. Here, we conducted a meta-analysis of previous studies to summarize the effects of facial emotion training on ASD. Our results show that the training produces a robust improvement in subsequent emotion recognition, while maintenance and generalization effects still need further investigation. To date, no experimentally verified improvements in social skills have been reported. En ligne : http://dx.doi.org/10.1002/aur.2565 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 Long-term follow-up of a randomized controlled trial comparing systemic family therapy (FT-S) added to treatment as usual (TAU) with TAU alone in adolescents with anorexia nervosa / Nathalie GODART in Journal of Child Psychology and Psychiatry, 63-11 (November 2022)
[article]
Titre : Long-term follow-up of a randomized controlled trial comparing systemic family therapy (FT-S) added to treatment as usual (TAU) with TAU alone in adolescents with anorexia nervosa Type de document : Texte imprimé et/ou numérique Auteurs : Nathalie GODART, Auteur ; Géraldine DORARD, Auteur ; Jeanne DUCLOS, Auteur ; FLORENCE CURT, Auteur ; Irène KAGANSKI, Auteur ; Lisa MINIER, Auteur ; Maurice CORCOS, Auteur ; Bruno FALISSARD, Auteur ; Ivan EISLER, Auteur ; Philippe JEAMMET, Auteur ; Sylvie BERTHOZ, Auteur Article en page(s) : p.1368-1380 Langues : Anglais (eng) Mots-clés : Female Adolescent Humans Anorexia Nervosa/therapy Family Therapy/methods Follow-Up Studies Feeding and Eating Disorders Ambulatory Care Treatment Outcome Randomized Controlled Trials as Topic Anorexia nervosa long-term follow-up outcome systemic family therapy Index. décimale : PER Périodiques Résumé : BACKGROUND: Randomized controlled trials showed the efficacy of family therapy for anorexia nervosa during adolescence, but studies examining its long-term beneficial effect are still needed. This article presents the results of a 54-month post-randomization follow-up of a previously reported randomized controlled trial that compared two post-hospitalization outpatient treatment programs: Treatment As Usual alone versus Systemic Family Therapy added to Treatment As Usual. METHODS: A consecutive series of 60 female adolescents with anorexia nervosa (DSM-IV) were randomized (30 per group). During the first 18 months, in the Treatment As Usual group, subjects received a multidisciplinary treatment. In the other group, Systemic Family Therapy sessions targeting intra-familial dynamics were added to Treatment As Usual. At 54 months, the primary outcome was defined using the Morgan and Russell global Outcome Categories (Good or Intermediate versus Poor). Secondary outcomes were the Global Outcome Assessment Schedule score, body mass index, amenorrhea, number of hospitalizations, eating disorder symptoms, psychopathological features, and family functioning. Analyses were carried out using an Intention-To-Treat with the Last Observation Carried Forward procedure. Data of 59/60 subjects were available. RESULTS: At 54 months, significant effects in favor of adding Systemic Family Therapy to Treatment As Usual were shown for the Global Outcome Categories (60% of Good/Intermediate versus 31% in the control group, p=.026), mean body mass index (p=.048), resumption of menses (70.0% vs. 40% p=.020), and mental state score (p=.010). Family cohesion scores were lower in the Systemic Family Therapy group (p = .040). CONCLUSIONS: Adding Systemic Family Therapy focusing on intra-familial dynamics to a multidimensional outpatient treatment program appeared to lead to a better long-term outcome in young women who suffered from severe anorexia nervosa during adolescence. En ligne : http://dx.doi.org/10.1111/jcpp.13583 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490
in Journal of Child Psychology and Psychiatry > 63-11 (November 2022) . - p.1368-1380[article] Long-term follow-up of a randomized controlled trial comparing systemic family therapy (FT-S) added to treatment as usual (TAU) with TAU alone in adolescents with anorexia nervosa [Texte imprimé et/ou numérique] / Nathalie GODART, Auteur ; Géraldine DORARD, Auteur ; Jeanne DUCLOS, Auteur ; FLORENCE CURT, Auteur ; Irène KAGANSKI, Auteur ; Lisa MINIER, Auteur ; Maurice CORCOS, Auteur ; Bruno FALISSARD, Auteur ; Ivan EISLER, Auteur ; Philippe JEAMMET, Auteur ; Sylvie BERTHOZ, Auteur . - p.1368-1380.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 63-11 (November 2022) . - p.1368-1380
Mots-clés : Female Adolescent Humans Anorexia Nervosa/therapy Family Therapy/methods Follow-Up Studies Feeding and Eating Disorders Ambulatory Care Treatment Outcome Randomized Controlled Trials as Topic Anorexia nervosa long-term follow-up outcome systemic family therapy Index. décimale : PER Périodiques Résumé : BACKGROUND: Randomized controlled trials showed the efficacy of family therapy for anorexia nervosa during adolescence, but studies examining its long-term beneficial effect are still needed. This article presents the results of a 54-month post-randomization follow-up of a previously reported randomized controlled trial that compared two post-hospitalization outpatient treatment programs: Treatment As Usual alone versus Systemic Family Therapy added to Treatment As Usual. METHODS: A consecutive series of 60 female adolescents with anorexia nervosa (DSM-IV) were randomized (30 per group). During the first 18 months, in the Treatment As Usual group, subjects received a multidisciplinary treatment. In the other group, Systemic Family Therapy sessions targeting intra-familial dynamics were added to Treatment As Usual. At 54 months, the primary outcome was defined using the Morgan and Russell global Outcome Categories (Good or Intermediate versus Poor). Secondary outcomes were the Global Outcome Assessment Schedule score, body mass index, amenorrhea, number of hospitalizations, eating disorder symptoms, psychopathological features, and family functioning. Analyses were carried out using an Intention-To-Treat with the Last Observation Carried Forward procedure. Data of 59/60 subjects were available. RESULTS: At 54 months, significant effects in favor of adding Systemic Family Therapy to Treatment As Usual were shown for the Global Outcome Categories (60% of Good/Intermediate versus 31% in the control group, p=.026), mean body mass index (p=.048), resumption of menses (70.0% vs. 40% p=.020), and mental state score (p=.010). Family cohesion scores were lower in the Systemic Family Therapy group (p = .040). CONCLUSIONS: Adding Systemic Family Therapy focusing on intra-familial dynamics to a multidimensional outpatient treatment program appeared to lead to a better long-term outcome in young women who suffered from severe anorexia nervosa during adolescence. En ligne : http://dx.doi.org/10.1111/jcpp.13583 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490 Large multicenter randomized trials in autism: key insights gained from the balovaptan clinical development program / Suma JACOB in Molecular Autism, 13 (2022)
Probiotics, prebiotics, synbiotics, and fecal microbiota transplantation in the treatment of behavioral symptoms of autism spectrum disorder: A systematic review / Q. TAN in Autism Research, 14-9 (September 2021)
[article]
Titre : Probiotics, prebiotics, synbiotics, and fecal microbiota transplantation in the treatment of behavioral symptoms of autism spectrum disorder: A systematic review Type de document : Texte imprimé et/ou numérique Auteurs : Q. TAN, Auteur ; C. E. ORSSO, Auteur ; E. C. DEEHAN, Auteur ; J. Y. KUNG, Auteur ; H. M. TUN, Auteur ; E. WINE, Auteur ; K. L. MADSEN, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; A. M. HAQQ, Auteur Article en page(s) : p.1820-1836 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/therapy Behavioral Symptoms Fecal Microbiota Transplantation Gastrointestinal Microbiome Humans Prebiotics Probiotics/therapeutic use Randomized Controlled Trials as Topic Synbiotics autism spectrum disorder fecal microbiota transplant gut microbiota prebiotic probiotic synbiotic Index. décimale : PER Périodiques Résumé : The emerging role of a microbiota-gut-brain axis in autism spectrum disorder (ASD) suggests that modulating gut microbial composition may offer a tractable approach to addressing the lifelong challenges of ASD. The aim of this systematic review was to provide an overview and critically evaluate the current evidence on the efficacy and safety of probiotic, prebiotic, synbiotic, and fecal microbiota transplantation therapies for core and co-occurring behavioral symptoms in individuals with ASD. Comprehensive searches of MEDLINE, EMBASE, Scopus, Web of Science Core Collection, Cochrane Library, and Google Scholar were performed from inception to March 5, 2020, and two update searches were completed on October 25, 2020, and April 22, 2021, respectively. A total of 4306 publications were identified, of which 14 articles met the inclusion criteria. Data were extracted independently by two reviewers using a preconstructed form. Results of probiotic studies do not confirm the supposed beneficial effect of probiotics on ASD, whereas prebiotics and synbiotic combinations appear to be efficacious in selective behavioral symptoms. Evidence of the efficacy of fecal microbiota transplantation in ASD is still scarce but supports further research. Overall, the current evidence base to suggest beneficial effects of these modalities in ASD is limited and inconclusive. More clinical trials are currently looking at the use of microbial-based therapies in ASD. With a robust double-blind randomized controlled protocol to investigate the efficacy, these trials should provide significant and definitive results. LAY SUMMARY: There is a link between altered gut bacteria and autism spectrum disorder. Some people believe that modulating bacterial composition in the gut may help reduce autism symptoms, but evidence from human studies suggesting beneficial effects of probiotic, prebiotic, and combination thereof as well as fecal transplants in autism spectrum disorder is limited and inconclusive. Current data should not encourage use of these modalities. Further clinical studies are needed. En ligne : http://dx.doi.org/10.1002/aur.2560 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=449
in Autism Research > 14-9 (September 2021) . - p.1820-1836[article] Probiotics, prebiotics, synbiotics, and fecal microbiota transplantation in the treatment of behavioral symptoms of autism spectrum disorder: A systematic review [Texte imprimé et/ou numérique] / Q. TAN, Auteur ; C. E. ORSSO, Auteur ; E. C. DEEHAN, Auteur ; J. Y. KUNG, Auteur ; H. M. TUN, Auteur ; E. WINE, Auteur ; K. L. MADSEN, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; A. M. HAQQ, Auteur . - p.1820-1836.
Langues : Anglais (eng)
in Autism Research > 14-9 (September 2021) . - p.1820-1836
Mots-clés : Autism Spectrum Disorder/therapy Behavioral Symptoms Fecal Microbiota Transplantation Gastrointestinal Microbiome Humans Prebiotics Probiotics/therapeutic use Randomized Controlled Trials as Topic Synbiotics autism spectrum disorder fecal microbiota transplant gut microbiota prebiotic probiotic synbiotic Index. décimale : PER Périodiques Résumé : The emerging role of a microbiota-gut-brain axis in autism spectrum disorder (ASD) suggests that modulating gut microbial composition may offer a tractable approach to addressing the lifelong challenges of ASD. The aim of this systematic review was to provide an overview and critically evaluate the current evidence on the efficacy and safety of probiotic, prebiotic, synbiotic, and fecal microbiota transplantation therapies for core and co-occurring behavioral symptoms in individuals with ASD. Comprehensive searches of MEDLINE, EMBASE, Scopus, Web of Science Core Collection, Cochrane Library, and Google Scholar were performed from inception to March 5, 2020, and two update searches were completed on October 25, 2020, and April 22, 2021, respectively. A total of 4306 publications were identified, of which 14 articles met the inclusion criteria. Data were extracted independently by two reviewers using a preconstructed form. Results of probiotic studies do not confirm the supposed beneficial effect of probiotics on ASD, whereas prebiotics and synbiotic combinations appear to be efficacious in selective behavioral symptoms. Evidence of the efficacy of fecal microbiota transplantation in ASD is still scarce but supports further research. Overall, the current evidence base to suggest beneficial effects of these modalities in ASD is limited and inconclusive. More clinical trials are currently looking at the use of microbial-based therapies in ASD. With a robust double-blind randomized controlled protocol to investigate the efficacy, these trials should provide significant and definitive results. LAY SUMMARY: There is a link between altered gut bacteria and autism spectrum disorder. Some people believe that modulating bacterial composition in the gut may help reduce autism symptoms, but evidence from human studies suggesting beneficial effects of probiotic, prebiotic, and combination thereof as well as fecal transplants in autism spectrum disorder is limited and inconclusive. Current data should not encourage use of these modalities. Further clinical studies are needed. En ligne : http://dx.doi.org/10.1002/aur.2560 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=449 A Systematic Review: Acceptance and Commitment Therapy for the Parents of Children and Adolescents with Autism Spectrum Disorder / J. JUVIN in Journal of Autism and Developmental Disorders, 52-1 (January 2022)
[article]
Titre : A Systematic Review: Acceptance and Commitment Therapy for the Parents of Children and Adolescents with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : J. JUVIN, Auteur ; S. SADEG, Auteur ; S. JULIEN-SWEERTS, Auteur ; R. ZEBDI, Auteur Article en page(s) : p.124-141 Langues : Anglais (eng) Mots-clés : Acceptance and Commitment Therapy Adolescent Autism Spectrum Disorder/therapy Child Humans Mental Health Parents Quality of Life Randomized Controlled Trials as Topic Acceptance and commitment therapy Autism spectrum disorder Systematic review Well-being Index. décimale : PER Périodiques Résumé : This systematic review investigated the effectiveness of acceptance and commitment therapy for the parents of children with autism spectrum disorder. PsychInfo, CINAHL, PubMed, Science Direct, and Psychology and Behavioral Sciences Collection were searched using the terms "acceptance and commitment", "autism" and "parent". A total of eight articles met the eligibility criteria. One study was a randomized controlled trial, one was quasi-experimental, and the other six were exploratory. Study outcomes concerned ACT processes, mental health, and quality of life. These studies showed that ACT interventions can be helpful for the parents of children with autism spectrum disorder. Nevertheless, as this field of research is relatively new, future research would benefit from creating a standard procedure and larger randomized controlled trials . En ligne : http://dx.doi.org/10.1007/s10803-021-04923-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454
in Journal of Autism and Developmental Disorders > 52-1 (January 2022) . - p.124-141[article] A Systematic Review: Acceptance and Commitment Therapy for the Parents of Children and Adolescents with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / J. JUVIN, Auteur ; S. SADEG, Auteur ; S. JULIEN-SWEERTS, Auteur ; R. ZEBDI, Auteur . - p.124-141.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 52-1 (January 2022) . - p.124-141
Mots-clés : Acceptance and Commitment Therapy Adolescent Autism Spectrum Disorder/therapy Child Humans Mental Health Parents Quality of Life Randomized Controlled Trials as Topic Acceptance and commitment therapy Autism spectrum disorder Systematic review Well-being Index. décimale : PER Périodiques Résumé : This systematic review investigated the effectiveness of acceptance and commitment therapy for the parents of children with autism spectrum disorder. PsychInfo, CINAHL, PubMed, Science Direct, and Psychology and Behavioral Sciences Collection were searched using the terms "acceptance and commitment", "autism" and "parent". A total of eight articles met the eligibility criteria. One study was a randomized controlled trial, one was quasi-experimental, and the other six were exploratory. Study outcomes concerned ACT processes, mental health, and quality of life. These studies showed that ACT interventions can be helpful for the parents of children with autism spectrum disorder. Nevertheless, as this field of research is relatively new, future research would benefit from creating a standard procedure and larger randomized controlled trials . En ligne : http://dx.doi.org/10.1007/s10803-021-04923-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454 Meta-Analysis of RCTs of Technology-Assisted Parent-Mediated Interventions for Children with ASD / Hong Ji PI in Journal of Autism and Developmental Disorders, 52-8 (August 2022)
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