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Long-term follow-up of a randomized controlled trial comparing systemic family therapy (FT-S) added to treatment as usual (TAU) with TAU alone in adolescents with anorexia nervosa / Nathalie GODART in Journal of Child Psychology and Psychiatry, 63-11 (November 2022)
[article]
Titre : Long-term follow-up of a randomized controlled trial comparing systemic family therapy (FT-S) added to treatment as usual (TAU) with TAU alone in adolescents with anorexia nervosa Type de document : Texte imprimé et/ou numérique Auteurs : Nathalie GODART, Auteur ; Géraldine DORARD, Auteur ; Jeanne DUCLOS, Auteur ; FLORENCE CURT, Auteur ; Irène KAGANSKI, Auteur ; Lisa MINIER, Auteur ; Maurice CORCOS, Auteur ; Bruno FALISSARD, Auteur ; Ivan EISLER, Auteur ; Philippe JEAMMET, Auteur ; Sylvie BERTHOZ, Auteur Article en page(s) : p.1368-1380 Langues : Anglais (eng) Mots-clés : Female Adolescent Humans Anorexia Nervosa/therapy Family Therapy/methods Follow-Up Studies Feeding and Eating Disorders Ambulatory Care Treatment Outcome Randomized Controlled Trials as Topic Anorexia nervosa long-term follow-up outcome systemic family therapy Index. décimale : PER Périodiques Résumé : BACKGROUND: Randomized controlled trials showed the efficacy of family therapy for anorexia nervosa during adolescence, but studies examining its long-term beneficial effect are still needed. This article presents the results of a 54-month post-randomization follow-up of a previously reported randomized controlled trial that compared two post-hospitalization outpatient treatment programs: Treatment As Usual alone versus Systemic Family Therapy added to Treatment As Usual. METHODS: A consecutive series of 60 female adolescents with anorexia nervosa (DSM-IV) were randomized (30 per group). During the first 18 months, in the Treatment As Usual group, subjects received a multidisciplinary treatment. In the other group, Systemic Family Therapy sessions targeting intra-familial dynamics were added to Treatment As Usual. At 54 months, the primary outcome was defined using the Morgan and Russell global Outcome Categories (Good or Intermediate versus Poor). Secondary outcomes were the Global Outcome Assessment Schedule score, body mass index, amenorrhea, number of hospitalizations, eating disorder symptoms, psychopathological features, and family functioning. Analyses were carried out using an Intention-To-Treat with the Last Observation Carried Forward procedure. Data of 59/60 subjects were available. RESULTS: At 54 months, significant effects in favor of adding Systemic Family Therapy to Treatment As Usual were shown for the Global Outcome Categories (60% of Good/Intermediate versus 31% in the control group, p=.026), mean body mass index (p=.048), resumption of menses (70.0% vs. 40% p=.020), and mental state score (p=.010). Family cohesion scores were lower in the Systemic Family Therapy group (p = .040). CONCLUSIONS: Adding Systemic Family Therapy focusing on intra-familial dynamics to a multidimensional outpatient treatment program appeared to lead to a better long-term outcome in young women who suffered from severe anorexia nervosa during adolescence. En ligne : http://dx.doi.org/10.1111/jcpp.13583 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490
in Journal of Child Psychology and Psychiatry > 63-11 (November 2022) . - p.1368-1380[article] Long-term follow-up of a randomized controlled trial comparing systemic family therapy (FT-S) added to treatment as usual (TAU) with TAU alone in adolescents with anorexia nervosa [Texte imprimé et/ou numérique] / Nathalie GODART, Auteur ; Géraldine DORARD, Auteur ; Jeanne DUCLOS, Auteur ; FLORENCE CURT, Auteur ; Irène KAGANSKI, Auteur ; Lisa MINIER, Auteur ; Maurice CORCOS, Auteur ; Bruno FALISSARD, Auteur ; Ivan EISLER, Auteur ; Philippe JEAMMET, Auteur ; Sylvie BERTHOZ, Auteur . - p.1368-1380.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 63-11 (November 2022) . - p.1368-1380
Mots-clés : Female Adolescent Humans Anorexia Nervosa/therapy Family Therapy/methods Follow-Up Studies Feeding and Eating Disorders Ambulatory Care Treatment Outcome Randomized Controlled Trials as Topic Anorexia nervosa long-term follow-up outcome systemic family therapy Index. décimale : PER Périodiques Résumé : BACKGROUND: Randomized controlled trials showed the efficacy of family therapy for anorexia nervosa during adolescence, but studies examining its long-term beneficial effect are still needed. This article presents the results of a 54-month post-randomization follow-up of a previously reported randomized controlled trial that compared two post-hospitalization outpatient treatment programs: Treatment As Usual alone versus Systemic Family Therapy added to Treatment As Usual. METHODS: A consecutive series of 60 female adolescents with anorexia nervosa (DSM-IV) were randomized (30 per group). During the first 18 months, in the Treatment As Usual group, subjects received a multidisciplinary treatment. In the other group, Systemic Family Therapy sessions targeting intra-familial dynamics were added to Treatment As Usual. At 54 months, the primary outcome was defined using the Morgan and Russell global Outcome Categories (Good or Intermediate versus Poor). Secondary outcomes were the Global Outcome Assessment Schedule score, body mass index, amenorrhea, number of hospitalizations, eating disorder symptoms, psychopathological features, and family functioning. Analyses were carried out using an Intention-To-Treat with the Last Observation Carried Forward procedure. Data of 59/60 subjects were available. RESULTS: At 54 months, significant effects in favor of adding Systemic Family Therapy to Treatment As Usual were shown for the Global Outcome Categories (60% of Good/Intermediate versus 31% in the control group, p=.026), mean body mass index (p=.048), resumption of menses (70.0% vs. 40% p=.020), and mental state score (p=.010). Family cohesion scores were lower in the Systemic Family Therapy group (p = .040). CONCLUSIONS: Adding Systemic Family Therapy focusing on intra-familial dynamics to a multidimensional outpatient treatment program appeared to lead to a better long-term outcome in young women who suffered from severe anorexia nervosa during adolescence. En ligne : http://dx.doi.org/10.1111/jcpp.13583 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490 Toddlers to teenagers: Long-term follow-up study of outcomes in autism spectrum disorder / Esther BEN-ITZCHAK in Autism, 24-1 (January 2020)
[article]
Titre : Toddlers to teenagers: Long-term follow-up study of outcomes in autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Esther BEN-ITZCHAK, Auteur ; Ditza A. ZACHOR, Auteur Article en page(s) : p.41-50 Langues : Anglais (eng) Mots-clés : adaptive behavior adolescents autism severity autism spectrum disorders cognitive ability long-term follow-up predictors toddlers Index. décimale : PER Périodiques Résumé : This prospective study examined the developmental changes over time of adolescents diagnosed in toddlerhood with autism spectrum disorder and searched for child characteristics at toddlerhood that predict outcome at adolescence. The study included 65 participants who were divided into low cognitive (developmental quotient < 85; N = 41) and high cognitive (developmental quotient 85; N = 21) groups in adolescence. Participants underwent a comprehensive assessment of cognitive ability, adaptive skills, and autism severity. Significant differences in the current clinical phenotypes and in developmental changes over time were found between the two cognitive groups. At baseline, the high cognitive group had significantly less severe social communication deficits. Only the high cognitive group showed a decrease in social communication deficits over time. Although the two groups did not differ in their adaptive skills at the time of diagnosis, the high cognitive group had better adaptive skills at adolescence. Better adaptive communication skills in toddlerhood were associated with better outcome at adolescence in cognitive ability, adaptive skills, and fewer autism symptoms. Less impaired baseline social affect and better cognitive ability predicted higher cognitive level and adaptive skills at adolescence. Cognitive potential of individuals with autism spectrum disorder plays an important role in long-term outcome and comprehensive evaluations at toddlerhood have strong prognostic value in adolescence. En ligne : http://dx.doi.org/10.1177/1362361319840226 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=414
in Autism > 24-1 (January 2020) . - p.41-50[article] Toddlers to teenagers: Long-term follow-up study of outcomes in autism spectrum disorder [Texte imprimé et/ou numérique] / Esther BEN-ITZCHAK, Auteur ; Ditza A. ZACHOR, Auteur . - p.41-50.
Langues : Anglais (eng)
in Autism > 24-1 (January 2020) . - p.41-50
Mots-clés : adaptive behavior adolescents autism severity autism spectrum disorders cognitive ability long-term follow-up predictors toddlers Index. décimale : PER Périodiques Résumé : This prospective study examined the developmental changes over time of adolescents diagnosed in toddlerhood with autism spectrum disorder and searched for child characteristics at toddlerhood that predict outcome at adolescence. The study included 65 participants who were divided into low cognitive (developmental quotient < 85; N = 41) and high cognitive (developmental quotient 85; N = 21) groups in adolescence. Participants underwent a comprehensive assessment of cognitive ability, adaptive skills, and autism severity. Significant differences in the current clinical phenotypes and in developmental changes over time were found between the two cognitive groups. At baseline, the high cognitive group had significantly less severe social communication deficits. Only the high cognitive group showed a decrease in social communication deficits over time. Although the two groups did not differ in their adaptive skills at the time of diagnosis, the high cognitive group had better adaptive skills at adolescence. Better adaptive communication skills in toddlerhood were associated with better outcome at adolescence in cognitive ability, adaptive skills, and fewer autism symptoms. Less impaired baseline social affect and better cognitive ability predicted higher cognitive level and adaptive skills at adolescence. Cognitive potential of individuals with autism spectrum disorder plays an important role in long-term outcome and comprehensive evaluations at toddlerhood have strong prognostic value in adolescence. En ligne : http://dx.doi.org/10.1177/1362361319840226 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=414 Fifteen-Year Prospective Follow-Up Study of Adult Outcomes of Autism Spectrum Disorders Among Children Attending Centers in Five Regional Departments in France: The EpiTED Cohort / Amaria BAGHDADLI in Journal of Autism and Developmental Disorders, 49-6 (June 2019)
[article]
Titre : Fifteen-Year Prospective Follow-Up Study of Adult Outcomes of Autism Spectrum Disorders Among Children Attending Centers in Five Regional Departments in France: The EpiTED Cohort Type de document : Texte imprimé et/ou numérique Auteurs : Amaria BAGHDADLI, Auteur ; C. RATTAZ, Auteur ; C. MICHELON, Auteur ; E. PERNON, Auteur ; Kerim M. MUNIR, Auteur Article en page(s) : p.2243-2256 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders Cohort France Long-term follow-up Longitudinal Index. décimale : PER Périodiques Résumé : There is limited data on long-term outcome of ASD with co-occurring intellectual disabilities (ID) and challenging behaviours in France. The EpiTED period cohort is a 15 years longitudinal study of the developmental trajectories of 281 children initially recruited at mean age of 5 years. Two contrasted developmental trajectories were identified. Low cognitive level, absence of language, and higher ASD scores at baseline were predictive of low growth at follow-up. As adults the participants were predisposed to persistent co-occurring challenging behaviours as well as underlying ID impacting their ability to function independently. The results underscore the need for development of services and supports for adults with ASD in France who may also have already lacked access to adequate interventions and support services. En ligne : https://dx.doi.org/10.1007/s10803-019-03901-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=400
in Journal of Autism and Developmental Disorders > 49-6 (June 2019) . - p.2243-2256[article] Fifteen-Year Prospective Follow-Up Study of Adult Outcomes of Autism Spectrum Disorders Among Children Attending Centers in Five Regional Departments in France: The EpiTED Cohort [Texte imprimé et/ou numérique] / Amaria BAGHDADLI, Auteur ; C. RATTAZ, Auteur ; C. MICHELON, Auteur ; E. PERNON, Auteur ; Kerim M. MUNIR, Auteur . - p.2243-2256.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 49-6 (June 2019) . - p.2243-2256
Mots-clés : Autism spectrum disorders Cohort France Long-term follow-up Longitudinal Index. décimale : PER Périodiques Résumé : There is limited data on long-term outcome of ASD with co-occurring intellectual disabilities (ID) and challenging behaviours in France. The EpiTED period cohort is a 15 years longitudinal study of the developmental trajectories of 281 children initially recruited at mean age of 5 years. Two contrasted developmental trajectories were identified. Low cognitive level, absence of language, and higher ASD scores at baseline were predictive of low growth at follow-up. As adults the participants were predisposed to persistent co-occurring challenging behaviours as well as underlying ID impacting their ability to function independently. The results underscore the need for development of services and supports for adults with ASD in France who may also have already lacked access to adequate interventions and support services. En ligne : https://dx.doi.org/10.1007/s10803-019-03901-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=400 Boys with Asperger Syndrome Grow Up: Psychiatric and Neurodevelopmental Disorders 20 Years After Initial Diagnosis / I. Carina GILLBERG in Journal of Autism and Developmental Disorders, 46-1 (January 2016)
[article]
Titre : Boys with Asperger Syndrome Grow Up: Psychiatric and Neurodevelopmental Disorders 20 Years After Initial Diagnosis Type de document : Texte imprimé et/ou numérique Auteurs : I. Carina GILLBERG, Auteur ; Adam HELLES, Auteur ; Eva BILLSTEDT, Auteur ; Christopher GILLBERG, Auteur Année de publication : 2016 Article en page(s) : p.74-82 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Asperger syndrome Psychiatric disorder Depression ADHD DCD Schizophrenia Neurodevelopmental Long-term follow-up Index. décimale : PER Périodiques Résumé : We examined comorbid psychiatric and neurodevelopmental disorders in fifty adult males (mean age 30 years) with Asperger syndrome (AS) diagnosed in childhood and followed up prospectively for almost two decades (13–26 years). Only three of the 50 men had never met criteria for an additional psychiatric/neurodevelopmental diagnosis and more than half had ongoing comorbidity (most commonly either ADHD or depression or both). Any psychiatric comorbidity increased the risk of poorer outcome. The minority of the AS group who no longer met criteria for a full diagnosis of an autism spectrum disorder were usually free of current psychiatric comorbidity. The high rate of psychiatric/neurodevelopmental comorbidities underscores the need for a full psychiatric/neurodevelopmental assessment at follow-up of males with AS. En ligne : http://dx.doi.org/10.1007/s10803-015-2544-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278
in Journal of Autism and Developmental Disorders > 46-1 (January 2016) . - p.74-82[article] Boys with Asperger Syndrome Grow Up: Psychiatric and Neurodevelopmental Disorders 20 Years After Initial Diagnosis [Texte imprimé et/ou numérique] / I. Carina GILLBERG, Auteur ; Adam HELLES, Auteur ; Eva BILLSTEDT, Auteur ; Christopher GILLBERG, Auteur . - 2016 . - p.74-82.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 46-1 (January 2016) . - p.74-82
Mots-clés : Autism spectrum disorder Asperger syndrome Psychiatric disorder Depression ADHD DCD Schizophrenia Neurodevelopmental Long-term follow-up Index. décimale : PER Périodiques Résumé : We examined comorbid psychiatric and neurodevelopmental disorders in fifty adult males (mean age 30 years) with Asperger syndrome (AS) diagnosed in childhood and followed up prospectively for almost two decades (13–26 years). Only three of the 50 men had never met criteria for an additional psychiatric/neurodevelopmental diagnosis and more than half had ongoing comorbidity (most commonly either ADHD or depression or both). Any psychiatric comorbidity increased the risk of poorer outcome. The minority of the AS group who no longer met criteria for a full diagnosis of an autism spectrum disorder were usually free of current psychiatric comorbidity. The high rate of psychiatric/neurodevelopmental comorbidities underscores the need for a full psychiatric/neurodevelopmental assessment at follow-up of males with AS. En ligne : http://dx.doi.org/10.1007/s10803-015-2544-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278 The British Chinese Adoption Study: orphanage care, adoption and mid-life outcomes / Alan RUSHTON in Journal of Child Psychology and Psychiatry, 54-11 (November 2013)
[article]
Titre : The British Chinese Adoption Study: orphanage care, adoption and mid-life outcomes Type de document : Texte imprimé et/ou numérique Auteurs : Alan RUSHTON, Auteur ; Margaret GRANT, Auteur ; Julia FEAST, Auteur ; John SIMMONDS, Auteur Article en page(s) : p.1215-1222 Langues : Anglais (eng) Mots-clés : Orphanage care international adoption long-term follow-up adult outcomes Index. décimale : PER Périodiques Résumé : Background While studies of ex-orphanage care show adverse effects on development, the longer-term impact on mid-life psychosocial functioning and physical health has not been established. Methods Orphanage records provided baseline data on a sample of 100 Hong Kong Chinese girls who were subsequently adopted into the UK. A mid-life follow-up using standardised questionnaires and face-to-face interviews assessed current circumstances, life satisfaction and mental and physical health outcomes. Comparisons were made with age-matched UK-born adopted and nonadopted women. Results Half the group spent between 1 and 2 years in orphanages, average age at adoptive placement was 23 months and 72% participated in the follow-up. Despite this poor early start, mid-life outcomes were commensurate with the comparison groups in terms of mental and physical health measures. Serious psychiatric and social difficulties were largely absent. Although the timing and extent of exposure to orphanage care did not influence outcome, participants' reports of poorer quality adoptive family experience and a negative view of their adoption were significantly associated with poorer mental health outcomes (difference in means = 0.76, 95% CI 1.33–0.19, p = .01; difference in means = 1.2, 95% CI 0.68–1.73, p = .01, respectively). Conclusions Moderately depriving orphanage care did not predict enduring adverse consequences in mid-life but subsequent poor adoption experience was associated with outcome. En ligne : http://dx.doi.org/10.1111/jcpp.12088 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=217
in Journal of Child Psychology and Psychiatry > 54-11 (November 2013) . - p.1215-1222[article] The British Chinese Adoption Study: orphanage care, adoption and mid-life outcomes [Texte imprimé et/ou numérique] / Alan RUSHTON, Auteur ; Margaret GRANT, Auteur ; Julia FEAST, Auteur ; John SIMMONDS, Auteur . - p.1215-1222.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 54-11 (November 2013) . - p.1215-1222
Mots-clés : Orphanage care international adoption long-term follow-up adult outcomes Index. décimale : PER Périodiques Résumé : Background While studies of ex-orphanage care show adverse effects on development, the longer-term impact on mid-life psychosocial functioning and physical health has not been established. Methods Orphanage records provided baseline data on a sample of 100 Hong Kong Chinese girls who were subsequently adopted into the UK. A mid-life follow-up using standardised questionnaires and face-to-face interviews assessed current circumstances, life satisfaction and mental and physical health outcomes. Comparisons were made with age-matched UK-born adopted and nonadopted women. Results Half the group spent between 1 and 2 years in orphanages, average age at adoptive placement was 23 months and 72% participated in the follow-up. Despite this poor early start, mid-life outcomes were commensurate with the comparison groups in terms of mental and physical health measures. Serious psychiatric and social difficulties were largely absent. Although the timing and extent of exposure to orphanage care did not influence outcome, participants' reports of poorer quality adoptive family experience and a negative view of their adoption were significantly associated with poorer mental health outcomes (difference in means = 0.76, 95% CI 1.33–0.19, p = .01; difference in means = 1.2, 95% CI 0.68–1.73, p = .01, respectively). Conclusions Moderately depriving orphanage care did not predict enduring adverse consequences in mid-life but subsequent poor adoption experience was associated with outcome. En ligne : http://dx.doi.org/10.1111/jcpp.12088 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=217