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Auteur Christopher David DESJARDINS |
Documents disponibles écrits par cet auteur (3)



Phenoscreening: a developmental approach to research domain criteria-motivated sampling / C. M. DOYLE in Journal of Child Psychology and Psychiatry, 62-7 (July 2021)
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[article]
Titre : Phenoscreening: a developmental approach to research domain criteria-motivated sampling Type de document : Texte imprimé et/ou numérique Auteurs : C. M. DOYLE, Auteur ; C. LASCH, Auteur ; E. P. VOLLMAN, Auteur ; Christopher David DESJARDINS, Auteur ; N. E. HELWIG, Auteur ; S. JACOB, Auteur ; J. J. WOLFF, Auteur ; J. T. ELISON, Auteur Article en page(s) : p.884-894 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis Child, Preschool Humans Infant Phenotype Development autism spectrum disorder communication infancy social behavior Index. décimale : PER Périodiques Résumé : BACKGROUND: To advance early identification efforts, we must detect and characterize neurodevelopmental sequelae of risk among population-based samples early in development. However, variability across the typical-to-atypical continuum and heterogeneity within and across early emerging psychiatric/neurodevelopmental disorders represent fundamental challenges to overcome. Identifying multidimensionally determined profiles of risk, agnostic to DSM categories, via data-driven computational approaches represents an avenue to improve early identification of risk. METHODS: Factor mixture modeling (FMM) was used to identify subgroups and characterize phenotypic risk profiles, derived from multiple parent-report measures of typical and atypical behaviors common to autism spectrum disorder, in a community-based sample of 17- to 25-month-old toddlers (n = 1,570). To examine the utility of risk profile classification, a subsample of toddlers (n = 107) was assessed on a distal, independent outcome examining internalizing, externalizing, and dysregulation at approximately 30 months. RESULTS: FMM results identified five asymmetrically sized subgroups. The putative high- and moderate-risk groups comprised 6% of the sample. Follow-up analyses corroborated the utility of the risk profile classification; the high-, moderate-, and low-risk groups were differentially stratified (i.e., HR > moderate-risk > LR) on outcome measures and comparison of high- and low-risk groups revealed large effect sizes for internalizing (d = 0.83), externalizing (d = 1.39), and dysregulation (d = 1.19). CONCLUSIONS: This data-driven approach yielded five subgroups of toddlers, the utility of which was corroborated by later outcomes. Data-driven approaches, leveraging multiple developmentally appropriate dimensional RDoC constructs, hold promise for future efforts aimed toward early identification of at-risk-phenotypes for a variety of early emerging neurodevelopmental disorders. En ligne : http://dx.doi.org/10.1111/jcpp.13341 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456
in Journal of Child Psychology and Psychiatry > 62-7 (July 2021) . - p.884-894[article] Phenoscreening: a developmental approach to research domain criteria-motivated sampling [Texte imprimé et/ou numérique] / C. M. DOYLE, Auteur ; C. LASCH, Auteur ; E. P. VOLLMAN, Auteur ; Christopher David DESJARDINS, Auteur ; N. E. HELWIG, Auteur ; S. JACOB, Auteur ; J. J. WOLFF, Auteur ; J. T. ELISON, Auteur . - p.884-894.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 62-7 (July 2021) . - p.884-894
Mots-clés : Autism Spectrum Disorder/diagnosis Child, Preschool Humans Infant Phenotype Development autism spectrum disorder communication infancy social behavior Index. décimale : PER Périodiques Résumé : BACKGROUND: To advance early identification efforts, we must detect and characterize neurodevelopmental sequelae of risk among population-based samples early in development. However, variability across the typical-to-atypical continuum and heterogeneity within and across early emerging psychiatric/neurodevelopmental disorders represent fundamental challenges to overcome. Identifying multidimensionally determined profiles of risk, agnostic to DSM categories, via data-driven computational approaches represents an avenue to improve early identification of risk. METHODS: Factor mixture modeling (FMM) was used to identify subgroups and characterize phenotypic risk profiles, derived from multiple parent-report measures of typical and atypical behaviors common to autism spectrum disorder, in a community-based sample of 17- to 25-month-old toddlers (n = 1,570). To examine the utility of risk profile classification, a subsample of toddlers (n = 107) was assessed on a distal, independent outcome examining internalizing, externalizing, and dysregulation at approximately 30 months. RESULTS: FMM results identified five asymmetrically sized subgroups. The putative high- and moderate-risk groups comprised 6% of the sample. Follow-up analyses corroborated the utility of the risk profile classification; the high-, moderate-, and low-risk groups were differentially stratified (i.e., HR > moderate-risk > LR) on outcome measures and comparison of high- and low-risk groups revealed large effect sizes for internalizing (d = 0.83), externalizing (d = 1.39), and dysregulation (d = 1.19). CONCLUSIONS: This data-driven approach yielded five subgroups of toddlers, the utility of which was corroborated by later outcomes. Data-driven approaches, leveraging multiple developmentally appropriate dimensional RDoC constructs, hold promise for future efforts aimed toward early identification of at-risk-phenotypes for a variety of early emerging neurodevelopmental disorders. En ligne : http://dx.doi.org/10.1111/jcpp.13341 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 The development of thought problems: A longitudinal family risk study of offspring of bipolar, unipolar, and well parents / Bonnie KLIMES-DOUGAN in Development and Psychopathology, 25-4 (November 2013)
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Titre : The development of thought problems: A longitudinal family risk study of offspring of bipolar, unipolar, and well parents Type de document : Texte imprimé et/ou numérique Auteurs : Bonnie KLIMES-DOUGAN, Auteur ; Christopher David DESJARDINS, Auteur ; Matthew G. JAMES, Auteur ; Angela J. NARAYAN, Auteur ; Jeffrey D. LONG, Auteur ; Kathryn R. CULLEN, Auteur ; Philip W. GOLD, Auteur ; Pedro E. MARTINEZ, Auteur Article en page(s) : p.1079-1091 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : There is growing evidence that many offspring of parents with bipolar disorder (BD) will develop moderate to severe forms of psychopathology during childhood and adolescence, including thought problems. The purpose of this study was to evaluate the developmental progression of thought problems within the context of a family risk study. Repeated assessments of thought problems, spanning approximately 15 years, were conducted in offspring (N = 192 from 98 families) of parents diagnosed with BD (O-BD), unipolar depression (O-UNI), or no significant psychiatric or medical problems (O-WELL). Survival analysis showed that the O-BD group had the greatest estimated probability of developing thought problems over time, followed by O-UNI, and then O-WELL and O-BD exhibiting higher levels of persistence than O-WELL. Parent-reported thought problems in childhood and adolescence predicted a range of problems in young adulthood. Disturbances in reality testing and other atypical behaviors are likely to disrupt progression through important developmental periods and to associate with poor outcomes. These findings are likely relevant to preventing the occurrence or progression of problems in offspring of bipolar parents. The study of thought problems across development represents an important area of continued research in children at risk for development of affective disorders. En ligne : http://dx.doi.org/10.1017/S0954579413000382 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=219
in Development and Psychopathology > 25-4 (November 2013) . - p.1079-1091[article] The development of thought problems: A longitudinal family risk study of offspring of bipolar, unipolar, and well parents [Texte imprimé et/ou numérique] / Bonnie KLIMES-DOUGAN, Auteur ; Christopher David DESJARDINS, Auteur ; Matthew G. JAMES, Auteur ; Angela J. NARAYAN, Auteur ; Jeffrey D. LONG, Auteur ; Kathryn R. CULLEN, Auteur ; Philip W. GOLD, Auteur ; Pedro E. MARTINEZ, Auteur . - p.1079-1091.
Langues : Anglais (eng)
in Development and Psychopathology > 25-4 (November 2013) . - p.1079-1091
Index. décimale : PER Périodiques Résumé : There is growing evidence that many offspring of parents with bipolar disorder (BD) will develop moderate to severe forms of psychopathology during childhood and adolescence, including thought problems. The purpose of this study was to evaluate the developmental progression of thought problems within the context of a family risk study. Repeated assessments of thought problems, spanning approximately 15 years, were conducted in offspring (N = 192 from 98 families) of parents diagnosed with BD (O-BD), unipolar depression (O-UNI), or no significant psychiatric or medical problems (O-WELL). Survival analysis showed that the O-BD group had the greatest estimated probability of developing thought problems over time, followed by O-UNI, and then O-WELL and O-BD exhibiting higher levels of persistence than O-WELL. Parent-reported thought problems in childhood and adolescence predicted a range of problems in young adulthood. Disturbances in reality testing and other atypical behaviors are likely to disrupt progression through important developmental periods and to associate with poor outcomes. These findings are likely relevant to preventing the occurrence or progression of problems in offspring of bipolar parents. The study of thought problems across development represents an important area of continued research in children at risk for development of affective disorders. En ligne : http://dx.doi.org/10.1017/S0954579413000382 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=219 The significance of childhood competence and problems for adult success in work: A developmental cascade analysis / Ann S. MASTEN in Development and Psychopathology, 22-3 (August 2010)
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Titre : The significance of childhood competence and problems for adult success in work: A developmental cascade analysis Type de document : Texte imprimé et/ou numérique Auteurs : Ann S. MASTEN, Auteur ; Jeffrey D. LONG, Auteur ; Christopher David DESJARDINS, Auteur ; Christopher M. MCCORMICK, Auteur ; Sally I-CHUN KUO, Auteur Année de publication : 2010 Article en page(s) : p.679-694 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Success in the domain of work is a salient developmental task of adulthood and a key indicator of adaptive function in the evaluation of health and psychopathology. Yet few studies have examined pathways to work competence, especially with strategies testing for cumulative cascade effects over time. Cascade models spanning 20 years were tested via structural equation modeling, linking work competence in early adulthood to antecedent competence in work and other domains of competence in childhood and emerging adulthood. Data were drawn from the Project Competence longitudinal study of 205 school children followed for 20 years. Relative fit of alternative models was evaluated by the Bayesian information criterion. As hypothesized, the effectiveness of adaptive behavior in earlier age-salient developmental task domains forecasted later work competence, which also showed strong concurrent links to competence in other domains. Results suggest there are numerous pathways by which success or failure in major developmental task domains in childhood and adolescence may influence adaptation in other domains and eventually work competence, both concurrently and cumulatively over time. Cascade effects highlight the potential significance for later work competence of childhood conduct (antisocial vs. rule-abiding behavior) and social competence with peers, in addition to the ongoing role that academic attainment may have for work success. Work competence also showed considerable stability over a 10-year period during early adulthood. Implications and applications for future research and intervention are discussed. En ligne : http://dx.doi.org/10.1017/s0954579410000362 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=108
in Development and Psychopathology > 22-3 (August 2010) . - p.679-694[article] The significance of childhood competence and problems for adult success in work: A developmental cascade analysis [Texte imprimé et/ou numérique] / Ann S. MASTEN, Auteur ; Jeffrey D. LONG, Auteur ; Christopher David DESJARDINS, Auteur ; Christopher M. MCCORMICK, Auteur ; Sally I-CHUN KUO, Auteur . - 2010 . - p.679-694.
Langues : Anglais (eng)
in Development and Psychopathology > 22-3 (August 2010) . - p.679-694
Index. décimale : PER Périodiques Résumé : Success in the domain of work is a salient developmental task of adulthood and a key indicator of adaptive function in the evaluation of health and psychopathology. Yet few studies have examined pathways to work competence, especially with strategies testing for cumulative cascade effects over time. Cascade models spanning 20 years were tested via structural equation modeling, linking work competence in early adulthood to antecedent competence in work and other domains of competence in childhood and emerging adulthood. Data were drawn from the Project Competence longitudinal study of 205 school children followed for 20 years. Relative fit of alternative models was evaluated by the Bayesian information criterion. As hypothesized, the effectiveness of adaptive behavior in earlier age-salient developmental task domains forecasted later work competence, which also showed strong concurrent links to competence in other domains. Results suggest there are numerous pathways by which success or failure in major developmental task domains in childhood and adolescence may influence adaptation in other domains and eventually work competence, both concurrently and cumulatively over time. Cascade effects highlight the potential significance for later work competence of childhood conduct (antisocial vs. rule-abiding behavior) and social competence with peers, in addition to the ongoing role that academic attainment may have for work success. Work competence also showed considerable stability over a 10-year period during early adulthood. Implications and applications for future research and intervention are discussed. En ligne : http://dx.doi.org/10.1017/s0954579410000362 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=108