Association between maternal adverse childhood experiences and mental health problems in offspring: An intergenerational study / Satomi DOI in Development and Psychopathology, 33-3 (August 2021)  

Public ISBD [article]  inDevelopment and Psychopathology > 33-3 (August 2021) . - p.1041-1058 Titre : Association between maternal adverse childhood experiences and mental health problems in offspring: An intergenerational study Type de document : Texte imprimé et/ou numérique Auteurs : Satomi DOI, Auteur ; Takeo FUJIWARA, Auteur ; Aya ISUMI, Auteur Article en page(s) : p.1041-1058 Langues : Anglais (eng) Mots-clés : behavior problems  depression  intergenerational effects  Japan  maternal adverse childhood experiences Index. décimale : PER Périodiques Résumé : The aim of this study is to examine the association between maternal adverse childhood experiences (ACEs) and mental health problems in adolescent offspring. Data were obtained from the population-based Kochi Child Health Impact of Living Difficulty (K-CHILD) study in 2016, and participants were 10,810 children in the fifth grade (3,144 pairs), eighth grade (3,497 pairs), and eleventh grade (4,169 pairs) living in Kochi Prefecture, Japan. Mothers of participating children were asked about their ACEs, childhood social economic status, current mental and physical health, current social economic status, positive parenting behaviors, child maltreatment, marital status, and child behavior problems using the Strength and Difficulty Questionnaire. Children reported their depressive symptoms using the Depression Self-Rating Scale. Children of mothers with a larger number of ACEs showed higher levels of behavior problems (p for trend <.001) and depressive symptoms (p for trend <.001), adjusting for potential confounders. In particular, maternal psychological distress mediated the association between maternal ACEs and child mental health. The adverse effects of maternal ACEs may have a direct intergenerational impact on behavior problems and depressive symptoms in adolescent offspring. Further studies to elucidate possible mediators are needed. En ligne : http://dx.doi.org/10.1017/S0954579420000334 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457 [article] Association between maternal adverse childhood experiences and mental health problems in offspring: An intergenerational study [Texte imprimé et/ou numérique] / Satomi DOI, Auteur ; Takeo FUJIWARA, Auteur ; Aya ISUMI, Auteur . - p.1041-1058. Langues : Anglais (eng) in Development and Psychopathology > 33-3 (August 2021) . - p.1041-1058 Mots-clés : behavior problems  depression  intergenerational effects  Japan  maternal adverse childhood experiences Index. décimale : PER Périodiques Résumé : The aim of this study is to examine the association between maternal adverse childhood experiences (ACEs) and mental health problems in adolescent offspring. Data were obtained from the population-based Kochi Child Health Impact of Living Difficulty (K-CHILD) study in 2016, and participants were 10,810 children in the fifth grade (3,144 pairs), eighth grade (3,497 pairs), and eleventh grade (4,169 pairs) living in Kochi Prefecture, Japan. Mothers of participating children were asked about their ACEs, childhood social economic status, current mental and physical health, current social economic status, positive parenting behaviors, child maltreatment, marital status, and child behavior problems using the Strength and Difficulty Questionnaire. Children reported their depressive symptoms using the Depression Self-Rating Scale. Children of mothers with a larger number of ACEs showed higher levels of behavior problems (p for trend <.001) and depressive symptoms (p for trend <.001), adjusting for potential confounders. In particular, maternal psychological distress mediated the association between maternal ACEs and child mental health. The adverse effects of maternal ACEs may have a direct intergenerational impact on behavior problems and depressive symptoms in adolescent offspring. Further studies to elucidate possible mediators are needed. En ligne : http://dx.doi.org/10.1017/S0954579420000334 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457

Factors influencing time lag between first parental concern and first visit to child psychiatric services in children with autism spectrum disorders in Japan / Takeo FUJIWARA in Research in Autism Spectrum Disorders, 5-1 (January-March 2011)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 5-1 (January-March 2011) . - p.584-591 Titre : Factors influencing time lag between first parental concern and first visit to child psychiatric services in children with autism spectrum disorders in Japan Type de document : Texte imprimé et/ou numérique Auteurs : Takeo FUJIWARA, Auteur ; Makiko OKUYAMA, Auteur ; Keiichi FUNAHASHI, Auteur Année de publication : 2011 Article en page(s) : p.584-591 Langues : Anglais (eng) Mots-clés : Autism-spectrum-disorder Pervasive-development-disorders Asperger's-syndrome Child-psychiatry Mental-health-system Index. décimale : PER Périodiques Résumé : The early assessment of autism spectrum disorders (ASDs) is important to improving patient outcomes, allowing family members to prepare for and cope with symptoms, and assisting in plans for appropriate educational opportunities. However, little is known about factors that influence the time lag between the parents’ first concerns and the first visit to a hospital that offers child psychiatric service. We investigated factors associated with the time lag between the first parental concern and the first visit to a hospital that offers child psychiatric services, among children in Japan with ASDs. A questionnaire was distributed to caregivers of ASD children, through child psychiatrists who work at 16 leading hospitals in child psychiatric services in Japan (N = 1513). We found that a younger child age, a caregiver's lack of knowledge of whom to consult when first concerned about symptoms, and the typically indirect means of attaining services (especially without a referral) each heightened the odds of there being a longer time lag. Visiting another institution, and then going to a hospital that offers child psychiatric services without a referral, was a typical scenario that often led to such time lags. A national health policy to facilitate a referral system that coordinates hospitals that offer child psychiatric services with other medical institutions, the health sector, the welfare sector, and educational institutions is needed, to promote the timely provision of child psychiatric services. En ligne : http://dx.doi.org/10.1016/j.rasd.2010.07.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=111 [article] Factors influencing time lag between first parental concern and first visit to child psychiatric services in children with autism spectrum disorders in Japan [Texte imprimé et/ou numérique] / Takeo FUJIWARA, Auteur ; Makiko OKUYAMA, Auteur ; Keiichi FUNAHASHI, Auteur . - 2011 . - p.584-591. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 5-1 (January-March 2011) . - p.584-591 Mots-clés : Autism-spectrum-disorder Pervasive-development-disorders Asperger's-syndrome Child-psychiatry Mental-health-system Index. décimale : PER Périodiques Résumé : The early assessment of autism spectrum disorders (ASDs) is important to improving patient outcomes, allowing family members to prepare for and cope with symptoms, and assisting in plans for appropriate educational opportunities. However, little is known about factors that influence the time lag between the parents’ first concerns and the first visit to a hospital that offers child psychiatric service. We investigated factors associated with the time lag between the first parental concern and the first visit to a hospital that offers child psychiatric services, among children in Japan with ASDs. A questionnaire was distributed to caregivers of ASD children, through child psychiatrists who work at 16 leading hospitals in child psychiatric services in Japan (N = 1513). We found that a younger child age, a caregiver's lack of knowledge of whom to consult when first concerned about symptoms, and the typically indirect means of attaining services (especially without a referral) each heightened the odds of there being a longer time lag. Visiting another institution, and then going to a hospital that offers child psychiatric services without a referral, was a typical scenario that often led to such time lags. A national health policy to facilitate a referral system that coordinates hospitals that offer child psychiatric services with other medical institutions, the health sector, the welfare sector, and educational institutions is needed, to promote the timely provision of child psychiatric services. En ligne : http://dx.doi.org/10.1016/j.rasd.2010.07.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=111

Household Income, Maternal Allostatic Load During Pregnancy, and Offspring With Autism Spectrum Disorders / Shoji F. NAKAYAMA ; Takeo FUJIWARA ; Environment THE JAPAN ; Group CHILDREN'S STUDY in Autism Research, 18-4 (April 2025)  

Public ISBD [article]  inAutism Research > 18-4 (April 2025) . - p.881-890 Titre : Household Income, Maternal Allostatic Load During Pregnancy, and Offspring With Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Shoji F. NAKAYAMA, Auteur ; Takeo FUJIWARA, Auteur ; Environment THE JAPAN, Auteur ; Group CHILDREN'S STUDY, Auteur Article en page(s) : p.881-890 Langues : Anglais (eng) Mots-clés : allostasis  autistic disorder  income  poverty Index. décimale : PER Périodiques Résumé : ABSTRACT Relative maternal poverty is a suggested social determinant of autism spectrum disorders (ASDs) in offspring; however, this association may be confounded by the maternal broader autism phenotype (BAP). The biological mechanisms underlying this association are largely understudied. We examined the association between household income during pregnancy and ASDs in offspring, adjusting for confounders including maternal BAP, and explored whether maternal chronic stress, measured by allostatic load (AL) during pregnancy, mediates this association. Data on 59,998 mother?child dyads were obtained from the Japan Environment and Children's Study, a nationwide birth cohort. Household income was categorized into tertiles (?6 million JPY) and offspring ASD diagnosis by age four was assessed via guardian's report. Bayesian logistic regression models indicated that mothers from low- and middle-income households had a 58% (95% credible interval [CI]: 28%?98%) and a 37% (95% CI: 12%?70%) higher risk of offspring ASDs, respectively, compared to those from high-income households. AL, defined as three or more out of 10 biomarkers in the highest risk quartile, did not mediate these associations. Low and middle household income during pregnancy was associated with a higher risk of ASD diagnosis, and high AL did not mediate this association. En ligne : https://doi.org/10.1002/aur.70022 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=554 [article] Household Income, Maternal Allostatic Load During Pregnancy, and Offspring With Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Shoji F. NAKAYAMA, Auteur ; Takeo FUJIWARA, Auteur ; Environment THE JAPAN, Auteur ; Group CHILDREN'S STUDY, Auteur . - p.881-890. Langues : Anglais (eng) in Autism Research > 18-4 (April 2025) . - p.881-890 Mots-clés : allostasis  autistic disorder  income  poverty Index. décimale : PER Périodiques Résumé : ABSTRACT Relative maternal poverty is a suggested social determinant of autism spectrum disorders (ASDs) in offspring; however, this association may be confounded by the maternal broader autism phenotype (BAP). The biological mechanisms underlying this association are largely understudied. We examined the association between household income during pregnancy and ASDs in offspring, adjusting for confounders including maternal BAP, and explored whether maternal chronic stress, measured by allostatic load (AL) during pregnancy, mediates this association. Data on 59,998 mother?child dyads were obtained from the Japan Environment and Children's Study, a nationwide birth cohort. Household income was categorized into tertiles (?6 million JPY) and offspring ASD diagnosis by age four was assessed via guardian's report. Bayesian logistic regression models indicated that mothers from low- and middle-income households had a 58% (95% credible interval [CI]: 28%?98%) and a 37% (95% CI: 12%?70%) higher risk of offspring ASDs, respectively, compared to those from high-income households. AL, defined as three or more out of 10 biomarkers in the highest risk quartile, did not mediate these associations. Low and middle household income during pregnancy was associated with a higher risk of ASD diagnosis, and high AL did not mediate this association. En ligne : https://doi.org/10.1002/aur.70022 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=554

Socioeconomic Status and the Risk of Suspected Autism Spectrum Disorders Among 18-Month-Old Toddlers in Japan: A Population-Based Study / Takeo FUJIWARA in Journal of Autism and Developmental Disorders, 44-6 (June 2014)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 44-6 (June 2014) . - p.1323-1331 Titre : Socioeconomic Status and the Risk of Suspected Autism Spectrum Disorders Among 18-Month-Old Toddlers in Japan: A Population-Based Study Type de document : Texte imprimé et/ou numérique Auteurs : Takeo FUJIWARA, Auteur Article en page(s) : p.1323-1331 Langues : Anglais (eng) Mots-clés : Autism  Autism spectrum disorders  Epidemiology  Health care system  Socioeconomic status Index. décimale : PER Périodiques Résumé : The association between family socioeconomic status (SES) and the suspected autism spectrum disorder (ASD) status of 18-month-old toddlers was investigated using a population-based sample in Japan, which has a universal healthcare system and a mandatory health checkup system for toddlers. Questionnaires including SES measurements and modified checklist for autism in toddlers were mailed to all families with 18-month-old toddlers in Chiba, a city near Tokyo (N = 6,061; response rate: 64 %). The results of logistic regression analysis (which were adjusted for potential confounders) indicated that low maternal education, but not paternal education or family income, were associated with having suspected ASD offspring. Lower maternal education was associated with an increased risk of autistic traits in Japan. En ligne : http://dx.doi.org/10.1007/s10803-013-1988-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=233 [article] Socioeconomic Status and the Risk of Suspected Autism Spectrum Disorders Among 18-Month-Old Toddlers in Japan: A Population-Based Study [Texte imprimé et/ou numérique] / Takeo FUJIWARA, Auteur . - p.1323-1331. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 44-6 (June 2014) . - p.1323-1331 Mots-clés : Autism  Autism spectrum disorders  Epidemiology  Health care system  Socioeconomic status Index. décimale : PER Périodiques Résumé : The association between family socioeconomic status (SES) and the suspected autism spectrum disorder (ASD) status of 18-month-old toddlers was investigated using a population-based sample in Japan, which has a universal healthcare system and a mandatory health checkup system for toddlers. Questionnaires including SES measurements and modified checklist for autism in toddlers were mailed to all families with 18-month-old toddlers in Chiba, a city near Tokyo (N = 6,061; response rate: 64 %). The results of logistic regression analysis (which were adjusted for potential confounders) indicated that low maternal education, but not paternal education or family income, were associated with having suspected ASD offspring. Lower maternal education was associated with an increased risk of autistic traits in Japan. En ligne : http://dx.doi.org/10.1007/s10803-013-1988-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=233

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