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Détail de l'auteur
Auteur Alberto ASCHERIO |
Documents disponibles écrits par cet auteur (5)



Erratum to: Maternal Early Life Factors Associated with Hormone Levels and the Risk of Having a Child with an Autism Spectrum Disorder in the Nurses Health Study II / Kristen LYALL in Journal of Autism and Developmental Disorders, 41-5 (May 2011)
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Titre : Erratum to: Maternal Early Life Factors Associated with Hormone Levels and the Risk of Having a Child with an Autism Spectrum Disorder in the Nurses Health Study II Type de document : Texte imprimé et/ou numérique Auteurs : Kristen LYALL, Auteur ; David L. PAULS, Auteur ; Susan L. SANTANGELO, Auteur ; Donna SPIEGELMAN, Auteur ; Alberto ASCHERIO, Auteur Année de publication : 2011 Article en page(s) : p.628 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-010-1097-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121
in Journal of Autism and Developmental Disorders > 41-5 (May 2011) . - p.628[article] Erratum to: Maternal Early Life Factors Associated with Hormone Levels and the Risk of Having a Child with an Autism Spectrum Disorder in the Nurses Health Study II [Texte imprimé et/ou numérique] / Kristen LYALL, Auteur ; David L. PAULS, Auteur ; Susan L. SANTANGELO, Auteur ; Donna SPIEGELMAN, Auteur ; Alberto ASCHERIO, Auteur . - 2011 . - p.628.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 41-5 (May 2011) . - p.628
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-010-1097-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121 Maternal Early Life Factors Associated with Hormone Levels and the Risk of Having a Child with an Autism Spectrum Disorder in the Nurses Health Study II / Kristen LYALL in Journal of Autism and Developmental Disorders, 41-5 (May 2011)
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Titre : Maternal Early Life Factors Associated with Hormone Levels and the Risk of Having a Child with an Autism Spectrum Disorder in the Nurses Health Study II Type de document : Texte imprimé et/ou numérique Auteurs : Kristen LYALL, Auteur ; David L. PAULS, Auteur ; Susan L. SANTANGELO, Auteur ; Donna SPIEGELMAN, Auteur ; Alberto ASCHERIO, Auteur Année de publication : 2011 Article en page(s) : p.618-627 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders Reproductive risk factors Hormonal factors Index. décimale : PER Périodiques Résumé : It is not known whether reproductive factors early in the mother’s life influence risk of autism spectrum disorders (ASD). We assessed maternal age at menarche, menstrual cycle characteristics during adolescence, oral contraceptive use prior to first birth, body shape, and body mass index (BMI) in association with ASD using binomial regression in a cohort study of 61,596 women, including 743 cases. Overall, early life factors were not associated with ASD, though early age at menarche (RR for age 10 or less = 1.54, 95% CI 1.18, 2.02, p = 0.0002) and BMI at age 18 of ≥30 (RR 2.03, 95% CI 1.34, 3.08, p = 0.0008) were significantly associated with increased risk of ASD. Further work should investigate the potential influence of these factors. En ligne : http://dx.doi.org/10.1007/s10803-010-1079-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121
in Journal of Autism and Developmental Disorders > 41-5 (May 2011) . - p.618-627[article] Maternal Early Life Factors Associated with Hormone Levels and the Risk of Having a Child with an Autism Spectrum Disorder in the Nurses Health Study II [Texte imprimé et/ou numérique] / Kristen LYALL, Auteur ; David L. PAULS, Auteur ; Susan L. SANTANGELO, Auteur ; Donna SPIEGELMAN, Auteur ; Alberto ASCHERIO, Auteur . - 2011 . - p.618-627.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 41-5 (May 2011) . - p.618-627
Mots-clés : Autism spectrum disorders Reproductive risk factors Hormonal factors Index. décimale : PER Périodiques Résumé : It is not known whether reproductive factors early in the mother’s life influence risk of autism spectrum disorders (ASD). We assessed maternal age at menarche, menstrual cycle characteristics during adolescence, oral contraceptive use prior to first birth, body shape, and body mass index (BMI) in association with ASD using binomial regression in a cohort study of 61,596 women, including 743 cases. Overall, early life factors were not associated with ASD, though early age at menarche (RR for age 10 or less = 1.54, 95% CI 1.18, 2.02, p = 0.0002) and BMI at age 18 of ≥30 (RR 2.03, 95% CI 1.34, 3.08, p = 0.0008) were significantly associated with increased risk of ASD. Further work should investigate the potential influence of these factors. En ligne : http://dx.doi.org/10.1007/s10803-010-1079-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121 Maternal exposure to intimate partner abuse before birth is associated with autism spectrum disorder in offspring / Andrea L. ROBERTS in Autism, 20-1 (January 2016)
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Titre : Maternal exposure to intimate partner abuse before birth is associated with autism spectrum disorder in offspring Type de document : Texte imprimé et/ou numérique Auteurs : Andrea L. ROBERTS, Auteur ; Kristen LYALL, Auteur ; Janet W. RICH-EDWARDS, Auteur ; Alberto ASCHERIO, Auteur ; Marc G. WEISSKOPF, Auteur Article en page(s) : p.26-36 Langues : Anglais (eng) Mots-clés : autism spectrum disorders environmental factors risk factor epidemiology Index. décimale : PER Périodiques Résumé : We sought to determine whether maternal (a) physical harm from intimate partner abuse during pregnancy or (b) sexual, emotional, or physical abuse before birth increased risk of autism spectrum disorder. We calculated risk ratios for autism spectrum disorder associated with abuse in a population-based cohort of women and their children (54,512 controls, 451 cases). Physical harm from abuse during pregnancy was not associated with autism spectrum disorder. However, autism spectrum disorder risk was increased in children of women who reported fear of partner or sexual, emotional, or physical abuse in the 2?years before the birth year (abuse in the year before the birth year: risk ratio?=?1.58, 95% confidence interval?=?1.04, 2.40; abuse in both of the 2?years before the birth year: risk ratio?=?2.16, 95% confidence interval?=?1.33, 3.50). Within-family results were similar, although did not reach statistical significance. Association of intimate partner abuse before the child’s birth year with autism spectrum disorder in the child was not accounted for by gestation length, birth weight, maternal smoking or alcohol consumption during pregnancy, gestational diabetes, preeclampsia, or history of induced abortion. En ligne : http://dx.doi.org/10.1177/1362361314566049 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277
in Autism > 20-1 (January 2016) . - p.26-36[article] Maternal exposure to intimate partner abuse before birth is associated with autism spectrum disorder in offspring [Texte imprimé et/ou numérique] / Andrea L. ROBERTS, Auteur ; Kristen LYALL, Auteur ; Janet W. RICH-EDWARDS, Auteur ; Alberto ASCHERIO, Auteur ; Marc G. WEISSKOPF, Auteur . - p.26-36.
Langues : Anglais (eng)
in Autism > 20-1 (January 2016) . - p.26-36
Mots-clés : autism spectrum disorders environmental factors risk factor epidemiology Index. décimale : PER Périodiques Résumé : We sought to determine whether maternal (a) physical harm from intimate partner abuse during pregnancy or (b) sexual, emotional, or physical abuse before birth increased risk of autism spectrum disorder. We calculated risk ratios for autism spectrum disorder associated with abuse in a population-based cohort of women and their children (54,512 controls, 451 cases). Physical harm from abuse during pregnancy was not associated with autism spectrum disorder. However, autism spectrum disorder risk was increased in children of women who reported fear of partner or sexual, emotional, or physical abuse in the 2?years before the birth year (abuse in the year before the birth year: risk ratio?=?1.58, 95% confidence interval?=?1.04, 2.40; abuse in both of the 2?years before the birth year: risk ratio?=?2.16, 95% confidence interval?=?1.33, 3.50). Within-family results were similar, although did not reach statistical significance. Association of intimate partner abuse before the child’s birth year with autism spectrum disorder in the child was not accounted for by gestation length, birth weight, maternal smoking or alcohol consumption during pregnancy, gestational diabetes, preeclampsia, or history of induced abortion. En ligne : http://dx.doi.org/10.1177/1362361314566049 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 Pregnancy complications and obstetric suboptimality in association with autism spectrum disorders in children of the nurses' health study II / Kristen LYALL in Autism Research, 5-1 (February 2012)
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Titre : Pregnancy complications and obstetric suboptimality in association with autism spectrum disorders in children of the nurses' health study II Type de document : Texte imprimé et/ou numérique Auteurs : Kristen LYALL, Auteur ; David L. PAULS, Auteur ; Donna SPIEGELMAN, Auteur ; Alberto ASCHERIO, Auteur ; Susan L. SANTANGELO, Auteur Année de publication : 2012 Article en page(s) : p.21-30 Langues : Anglais (eng) Mots-clés : autism spectrum disorders gestational diabetes obstetric complications pregnancy complications Index. décimale : PER Périodiques Résumé : The authors examined pregnancy and obstetric complications in association with autism spectrum disorders (ASD) in children of participants from the Nurses' Health Study II, a prospective national cohort with information collected through biennial mailed questionnaires since 1989. Logistic regression was used to obtain crude and adjusted odds ratios for ASD, and by diagnostic subgroup. Seven hundred and ninety-three cases were reported among 66,445 pregnancies. Pregnancy complications and obstetric suboptimality factors were assessed by maternal report of occurrence in first birth and, in secondary analyses, in any birth. Complications and a suboptimality score were significantly associated with having a child with ASD (OR 1.49, 95% CI 1.26, 1.77, P<0.0001 for pregnancy complications in first birth and 2.76, 95% CI 2.04, 3.74, P<0.0001 comparing individuals with four or more obstetric suboptimality factors in first birth to those with none; results similar when assessed in any birth). In particular, gestational diabetes was associated with a significantly increased risk of ASD in results of primary and sensitivity analyses (OR in primary analysis = 1.76, 95% CI 1.34, 2.32, P<0.0001); suboptimal parity and suboptimal age-at-first-birth were also individual factors associated with ASD. Associations were similar by diagnostic subgroup, suggesting autism, Asperger syndrome, and other Pervasive Developmental Disorders are all associated with pregnancy complications. Consistent with previous research, the general class of pregnancy complications was associated with ASD as a whole. Additional work will be required to more fully assess the role of gestational diabetes. En ligne : http://dx.doi.org/10.1002/aur.228 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=153
in Autism Research > 5-1 (February 2012) . - p.21-30[article] Pregnancy complications and obstetric suboptimality in association with autism spectrum disorders in children of the nurses' health study II [Texte imprimé et/ou numérique] / Kristen LYALL, Auteur ; David L. PAULS, Auteur ; Donna SPIEGELMAN, Auteur ; Alberto ASCHERIO, Auteur ; Susan L. SANTANGELO, Auteur . - 2012 . - p.21-30.
Langues : Anglais (eng)
in Autism Research > 5-1 (February 2012) . - p.21-30
Mots-clés : autism spectrum disorders gestational diabetes obstetric complications pregnancy complications Index. décimale : PER Périodiques Résumé : The authors examined pregnancy and obstetric complications in association with autism spectrum disorders (ASD) in children of participants from the Nurses' Health Study II, a prospective national cohort with information collected through biennial mailed questionnaires since 1989. Logistic regression was used to obtain crude and adjusted odds ratios for ASD, and by diagnostic subgroup. Seven hundred and ninety-three cases were reported among 66,445 pregnancies. Pregnancy complications and obstetric suboptimality factors were assessed by maternal report of occurrence in first birth and, in secondary analyses, in any birth. Complications and a suboptimality score were significantly associated with having a child with ASD (OR 1.49, 95% CI 1.26, 1.77, P<0.0001 for pregnancy complications in first birth and 2.76, 95% CI 2.04, 3.74, P<0.0001 comparing individuals with four or more obstetric suboptimality factors in first birth to those with none; results similar when assessed in any birth). In particular, gestational diabetes was associated with a significantly increased risk of ASD in results of primary and sensitivity analyses (OR in primary analysis = 1.76, 95% CI 1.34, 2.32, P<0.0001); suboptimal parity and suboptimal age-at-first-birth were also individual factors associated with ASD. Associations were similar by diagnostic subgroup, suggesting autism, Asperger syndrome, and other Pervasive Developmental Disorders are all associated with pregnancy complications. Consistent with previous research, the general class of pregnancy complications was associated with ASD as a whole. Additional work will be required to more fully assess the role of gestational diabetes. En ligne : http://dx.doi.org/10.1002/aur.228 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=153 Women's posttraumatic stress symptoms and autism spectrum disorder in their children / Andrea L. ROBERTS in Research in Autism Spectrum Disorders, 8-6 (June 2014)
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Titre : Women's posttraumatic stress symptoms and autism spectrum disorder in their children Type de document : Texte imprimé et/ou numérique Auteurs : Andrea L. ROBERTS, Auteur ; Karestan C. KOENEN, Auteur ; Kristen LYALL, Auteur ; Alberto ASCHERIO, Auteur ; Marc G. WEISSKOPF, Auteur Article en page(s) : p.608-616 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Posttraumatic stress disorder Gestational effects Index. décimale : PER Périodiques Résumé : Maternal posttraumatic stress disorder (PTSD) may be associated with autism spectrum disorder (ASD) in offspring through multiple pathways: maternal stress may affect the fetus; ASD in children may increase risk of PTSD in mothers; and the two disorders may share genetic risk. Understanding whether maternal PTSD is associated with child's ASD is important for clinicians treating children with ASD, as PTSD in parents is associated with poorer family functioning. We examined the association of maternal PTSD with offspring ASD in a large US cohort (N ASD cases = 413, N controls = 42,868). Mother's PTSD symptoms were strongly associated with child's ASD (RR 4–5 PTSD symptoms = 1.98, 95% CI = 1.39, 2.81; RR 6–7 symptoms = 2.89, 95% CI = 2.00, 4.18). Clinicians treating persons with ASD should be aware of elevated risk of PTSD in the mother. Genetic studies should investigate PTSD risk alleles in relation to ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.02.004 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=232
in Research in Autism Spectrum Disorders > 8-6 (June 2014) . - p.608-616[article] Women's posttraumatic stress symptoms and autism spectrum disorder in their children [Texte imprimé et/ou numérique] / Andrea L. ROBERTS, Auteur ; Karestan C. KOENEN, Auteur ; Kristen LYALL, Auteur ; Alberto ASCHERIO, Auteur ; Marc G. WEISSKOPF, Auteur . - p.608-616.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 8-6 (June 2014) . - p.608-616
Mots-clés : Autism spectrum disorder Posttraumatic stress disorder Gestational effects Index. décimale : PER Périodiques Résumé : Maternal posttraumatic stress disorder (PTSD) may be associated with autism spectrum disorder (ASD) in offspring through multiple pathways: maternal stress may affect the fetus; ASD in children may increase risk of PTSD in mothers; and the two disorders may share genetic risk. Understanding whether maternal PTSD is associated with child's ASD is important for clinicians treating children with ASD, as PTSD in parents is associated with poorer family functioning. We examined the association of maternal PTSD with offspring ASD in a large US cohort (N ASD cases = 413, N controls = 42,868). Mother's PTSD symptoms were strongly associated with child's ASD (RR 4–5 PTSD symptoms = 1.98, 95% CI = 1.39, 2.81; RR 6–7 symptoms = 2.89, 95% CI = 2.00, 4.18). Clinicians treating persons with ASD should be aware of elevated risk of PTSD in the mother. Genetic studies should investigate PTSD risk alleles in relation to ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.02.004 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=232