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Auteur Larry J. YOUNG |
Documents disponibles écrits par cet auteur (4)



ASD Screening with the Child Behavior Checklist/1.5-5 in the Study to Explore Early Development / S. E. LEVY in Journal of Autism and Developmental Disorders, 49-6 (June 2019)
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[article]
Titre : ASD Screening with the Child Behavior Checklist/1.5-5 in the Study to Explore Early Development Type de document : Texte imprimé et/ou numérique Auteurs : S. E. LEVY, Auteur ; L. A. RESCORLA, Auteur ; J. L. CHITTAMS, Auteur ; T. J. KRAL, Auteur ; E. J. MOODY, Auteur ; J. PANDEY, Auteur ; J. A. PINTO-MARTIN, Auteur ; A. T. POMYKACZ, Auteur ; A. RAMIREZ, Auteur ; N. REYES, Auteur ; C. R. ROSENBERG, Auteur ; Laura A. SCHIEVE, Auteur ; A. THOMPSON, Auteur ; Larry J. YOUNG, Auteur ; J. ZHANG, Auteur ; Lisa D. WIGGINS, Auteur Article en page(s) : p.2348-2357 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder (ASD) Child Behavior Checklist (CBCL) Developmental delay (DD) Index. décimale : PER Périodiques Résumé : We analyzed CBCL/1(1/2)-5 Pervasive Developmental Problems (DSM-PDP) scores in 3- to 5-year-olds from the Study to Explore Early Development (SEED), a multi-site case control study, with the objective to discriminate children with ASD (N = 656) from children with Developmental Delay (DD) (N = 646), children with Developmental Delay (DD) plus ASD features (DD-AF) (N = 284), and population controls (POP) (N = 827). ASD diagnosis was confirmed with the ADOS and ADI-R. With a cut-point of T >/= 65, sensitivity was 80% for ASD, with specificity varying across groups: POP (0.93), DD-noAF (0.85), and DD-AF (0.50). One-way ANOVA yielded a large group effect (eta(2) = 0.50). Our results support the CBCL/1(1/2)-5's as a time-efficient ASD screener for identifying preschoolers needing further evaluation. En ligne : https://dx.doi.org/10.1007/s10803-019-03895-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=400
in Journal of Autism and Developmental Disorders > 49-6 (June 2019) . - p.2348-2357[article] ASD Screening with the Child Behavior Checklist/1.5-5 in the Study to Explore Early Development [Texte imprimé et/ou numérique] / S. E. LEVY, Auteur ; L. A. RESCORLA, Auteur ; J. L. CHITTAMS, Auteur ; T. J. KRAL, Auteur ; E. J. MOODY, Auteur ; J. PANDEY, Auteur ; J. A. PINTO-MARTIN, Auteur ; A. T. POMYKACZ, Auteur ; A. RAMIREZ, Auteur ; N. REYES, Auteur ; C. R. ROSENBERG, Auteur ; Laura A. SCHIEVE, Auteur ; A. THOMPSON, Auteur ; Larry J. YOUNG, Auteur ; J. ZHANG, Auteur ; Lisa D. WIGGINS, Auteur . - p.2348-2357.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 49-6 (June 2019) . - p.2348-2357
Mots-clés : Autism spectrum disorder (ASD) Child Behavior Checklist (CBCL) Developmental delay (DD) Index. décimale : PER Périodiques Résumé : We analyzed CBCL/1(1/2)-5 Pervasive Developmental Problems (DSM-PDP) scores in 3- to 5-year-olds from the Study to Explore Early Development (SEED), a multi-site case control study, with the objective to discriminate children with ASD (N = 656) from children with Developmental Delay (DD) (N = 646), children with Developmental Delay (DD) plus ASD features (DD-AF) (N = 284), and population controls (POP) (N = 827). ASD diagnosis was confirmed with the ADOS and ADI-R. With a cut-point of T >/= 65, sensitivity was 80% for ASD, with specificity varying across groups: POP (0.93), DD-noAF (0.85), and DD-AF (0.50). One-way ANOVA yielded a large group effect (eta(2) = 0.50). Our results support the CBCL/1(1/2)-5's as a time-efficient ASD screener for identifying preschoolers needing further evaluation. En ligne : https://dx.doi.org/10.1007/s10803-019-03895-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=400 Early life influences on child weight outcomes in the Study to Explore Early Development / T. V. KRAL in Autism, 23-4 (May 2019)
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Titre : Early life influences on child weight outcomes in the Study to Explore Early Development Type de document : Texte imprimé et/ou numérique Auteurs : T. V. KRAL, Auteur ; J. CHITTAMS, Auteur ; C. B. BRADLEY, Auteur ; Julie L. DANIELS, Auteur ; Carolyn G. DIGUISEPPI, Auteur ; S. L. JOHNSON, Auteur ; J. PANDEY, Auteur ; J. A. PINTO-MARTIN, Auteur ; N. RAHAI, Auteur ; A. RAMIREZ, Auteur ; Laura A. SCHIEVE, Auteur ; A. THOMPSON, Auteur ; G. WINDHAM, Auteur ; W. YORK, Auteur ; Larry J. YOUNG, Auteur ; S. E. LEVY, Auteur Article en page(s) : p.954-962 Langues : Anglais (eng) Mots-clés : autism spectrum disorder gestational weight gain maternal obesity medical comorbidity obesity Index. décimale : PER Périodiques Résumé : We examined associations between child body mass index at 2-5 years and maternal pre-pregnancy body mass index, gestational weight gain, and rapid weight gain during infancy in children with autism spectrum disorder, developmental delays, or population controls. The Study to Explore Early Development is a multi-site case-control study of children, aged 2-5 years, classified as autism spectrum disorder ( n = 668), developmental delays ( n = 914), or population controls ( n = 884). Maternal gestational weight gain was compared to the Institute of Medicine recommendations. Rapid weight gain was a change in weight-for-age z-scores from birth to 6 months > 0.67 standard deviations. After adjusting for case status, mothers with pre-pregnancy overweight/obesity were 2.38 times (95% confidence interval: 1.96-2.90) more likely, and mothers who exceeded gestational weight gain recommendations were 1.48 times (95% confidence interval: 1.17-1.87) more likely, to have an overweight/obese child than other mothers ( P < 0.001). Children with autism spectrum disorder showed the highest frequency of rapid weight gain (44%) and were 3.47 times (95% confidence interval: 1.85-6.51) more likely to be overweight/obese as children with autism spectrum disorder without rapid weight gain ( P < 0.001). Helping mothers achieve a healthy pre-pregnancy body mass index and gestational weight gain represent important targets for all children. Healthy infant growth patterns carry special importance for children at increased risk for an autism spectrum disorder diagnosis. En ligne : http://dx.doi.org/10.1177/1362361318791545 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=397
in Autism > 23-4 (May 2019) . - p.954-962[article] Early life influences on child weight outcomes in the Study to Explore Early Development [Texte imprimé et/ou numérique] / T. V. KRAL, Auteur ; J. CHITTAMS, Auteur ; C. B. BRADLEY, Auteur ; Julie L. DANIELS, Auteur ; Carolyn G. DIGUISEPPI, Auteur ; S. L. JOHNSON, Auteur ; J. PANDEY, Auteur ; J. A. PINTO-MARTIN, Auteur ; N. RAHAI, Auteur ; A. RAMIREZ, Auteur ; Laura A. SCHIEVE, Auteur ; A. THOMPSON, Auteur ; G. WINDHAM, Auteur ; W. YORK, Auteur ; Larry J. YOUNG, Auteur ; S. E. LEVY, Auteur . - p.954-962.
Langues : Anglais (eng)
in Autism > 23-4 (May 2019) . - p.954-962
Mots-clés : autism spectrum disorder gestational weight gain maternal obesity medical comorbidity obesity Index. décimale : PER Périodiques Résumé : We examined associations between child body mass index at 2-5 years and maternal pre-pregnancy body mass index, gestational weight gain, and rapid weight gain during infancy in children with autism spectrum disorder, developmental delays, or population controls. The Study to Explore Early Development is a multi-site case-control study of children, aged 2-5 years, classified as autism spectrum disorder ( n = 668), developmental delays ( n = 914), or population controls ( n = 884). Maternal gestational weight gain was compared to the Institute of Medicine recommendations. Rapid weight gain was a change in weight-for-age z-scores from birth to 6 months > 0.67 standard deviations. After adjusting for case status, mothers with pre-pregnancy overweight/obesity were 2.38 times (95% confidence interval: 1.96-2.90) more likely, and mothers who exceeded gestational weight gain recommendations were 1.48 times (95% confidence interval: 1.17-1.87) more likely, to have an overweight/obese child than other mothers ( P < 0.001). Children with autism spectrum disorder showed the highest frequency of rapid weight gain (44%) and were 3.47 times (95% confidence interval: 1.85-6.51) more likely to be overweight/obese as children with autism spectrum disorder without rapid weight gain ( P < 0.001). Helping mothers achieve a healthy pre-pregnancy body mass index and gestational weight gain represent important targets for all children. Healthy infant growth patterns carry special importance for children at increased risk for an autism spectrum disorder diagnosis. En ligne : http://dx.doi.org/10.1177/1362361318791545 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=397 Maternal Pre-pregnancy Body Mass Index and Gestational Weight Gain in Relation to Autism Spectrum Disorder and other Developmental Disorders in Offspring / G. C. WINDHAM in Autism Research, 12-2 (February 2019)
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[article]
Titre : Maternal Pre-pregnancy Body Mass Index and Gestational Weight Gain in Relation to Autism Spectrum Disorder and other Developmental Disorders in Offspring Type de document : Texte imprimé et/ou numérique Auteurs : G. C. WINDHAM, Auteur ; M. ANDERSON, Auteur ; K. LYALL, Auteur ; Julie L. DANIELS, Auteur ; T. V. E. KRAL, Auteur ; Lisa A. CROEN, Auteur ; S. E. LEVY, Auteur ; C. B. BRADLEY, Auteur ; C. CORDERO, Auteur ; Larry J. YOUNG, Auteur ; Laura A. SCHIEVE, Auteur Article en page(s) : p.316-327 Langues : Anglais (eng) Mots-clés : Bmi autism autism spectrum disorder developmental delay epidemiology gestational weight gain maternal child health obesity Index. décimale : PER Périodiques Résumé : Most prior studies examining maternal pre-pregnancy body mass index (BMI) in relation to offspring autism spectrum disorders (ASD) have reported an association, though findings are not uniform and few have also examined gestational weight gain (GWG). Therefore, we examined both in the Study to Explore Early Development, a multi-site case-control study of children born in 2003-2006. Children identified from clinics, schools, and birth certificates were enrolled at ages 2-5 year and using standardized developmental evaluations, classified as: ASD, other developmental delays (DD), or population-based controls. Maternal height, weight, and GWG were self-reported during the telephone interview. Three primary weight risk factors were examined: (a) Pre-pregnancy BMI, classified as underweight to obese, (b) GWG continuous and categorized as quintiles, and (c) Institute of Medicine clinical weight-gain recommendations. Odds ratios adjusted (AOR) for sociodemographic and prenatal factors were calculated among term singletons, comparing the ASD (n = 540) or DD (n = 720) groups to the control group (n = 776). The AOR of ASD and maternal obesity was 1.37 (95%CI 0.98-1.92). Associations with higher GWG were stronger (Quintile5 vs. Quintile3 AOR = 1.58, 95%CI 1.08-2.31), and particularly so among overweight/obese women (AOR = 1.90, 95%CI 0.98-3.68). DD was associated with maternal overweight and obesity (obesity AOR = 1.48, 95%CI 1.08-2.02), but not with total GWG or clinical recommendations. High maternal BMI and GWG are risk factors for other pregnancy and child outcomes, and our results suggest they may also represent modifiable risk factors for neurodevelopmental outcomes. Autism Res 2019, 12: 316-327 (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: In a large, national study, we found that children with autism were more likely than unaffected children to have mothers with higher weight gain during pregnancy; risk of autism may be even stronger if mothers were also overweight before pregnancy. Children with other developmental delays were more likely to have mothers who were overweight or obese before pregnancy, but not who gained more weight during pregnancy. Overweight and weight gain may represent factors that could be modified. En ligne : http://dx.doi.org/10.1002/aur.2057 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=383
in Autism Research > 12-2 (February 2019) . - p.316-327[article] Maternal Pre-pregnancy Body Mass Index and Gestational Weight Gain in Relation to Autism Spectrum Disorder and other Developmental Disorders in Offspring [Texte imprimé et/ou numérique] / G. C. WINDHAM, Auteur ; M. ANDERSON, Auteur ; K. LYALL, Auteur ; Julie L. DANIELS, Auteur ; T. V. E. KRAL, Auteur ; Lisa A. CROEN, Auteur ; S. E. LEVY, Auteur ; C. B. BRADLEY, Auteur ; C. CORDERO, Auteur ; Larry J. YOUNG, Auteur ; Laura A. SCHIEVE, Auteur . - p.316-327.
Langues : Anglais (eng)
in Autism Research > 12-2 (February 2019) . - p.316-327
Mots-clés : Bmi autism autism spectrum disorder developmental delay epidemiology gestational weight gain maternal child health obesity Index. décimale : PER Périodiques Résumé : Most prior studies examining maternal pre-pregnancy body mass index (BMI) in relation to offspring autism spectrum disorders (ASD) have reported an association, though findings are not uniform and few have also examined gestational weight gain (GWG). Therefore, we examined both in the Study to Explore Early Development, a multi-site case-control study of children born in 2003-2006. Children identified from clinics, schools, and birth certificates were enrolled at ages 2-5 year and using standardized developmental evaluations, classified as: ASD, other developmental delays (DD), or population-based controls. Maternal height, weight, and GWG were self-reported during the telephone interview. Three primary weight risk factors were examined: (a) Pre-pregnancy BMI, classified as underweight to obese, (b) GWG continuous and categorized as quintiles, and (c) Institute of Medicine clinical weight-gain recommendations. Odds ratios adjusted (AOR) for sociodemographic and prenatal factors were calculated among term singletons, comparing the ASD (n = 540) or DD (n = 720) groups to the control group (n = 776). The AOR of ASD and maternal obesity was 1.37 (95%CI 0.98-1.92). Associations with higher GWG were stronger (Quintile5 vs. Quintile3 AOR = 1.58, 95%CI 1.08-2.31), and particularly so among overweight/obese women (AOR = 1.90, 95%CI 0.98-3.68). DD was associated with maternal overweight and obesity (obesity AOR = 1.48, 95%CI 1.08-2.02), but not with total GWG or clinical recommendations. High maternal BMI and GWG are risk factors for other pregnancy and child outcomes, and our results suggest they may also represent modifiable risk factors for neurodevelopmental outcomes. Autism Res 2019, 12: 316-327 (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: In a large, national study, we found that children with autism were more likely than unaffected children to have mothers with higher weight gain during pregnancy; risk of autism may be even stronger if mothers were also overweight before pregnancy. Children with other developmental delays were more likely to have mothers who were overweight or obese before pregnancy, but not who gained more weight during pregnancy. Overweight and weight gain may represent factors that could be modified. En ligne : http://dx.doi.org/10.1002/aur.2057 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=383 Oxytocin, Vasopressin, and Social Behavior: Implications for Autism Spectrum Disorders / Meera E. MODI
Titre : Oxytocin, Vasopressin, and Social Behavior: Implications for Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Meera E. MODI, Auteur ; Larry J. YOUNG, Auteur Année de publication : 2011 Importance : p.593-610 Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=139 Oxytocin, Vasopressin, and Social Behavior: Implications for Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Meera E. MODI, Auteur ; Larry J. YOUNG, Auteur . - 2011 . - p.593-610.
Langues : Anglais (eng)
Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=139 Exemplaires
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