Autism and immune factors: A comprehensive review / Kimberly A. STIGLER in Research in Autism Spectrum Disorders, 3-4 (October-December 2009)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 3-4 (October-December 2009) . - p.840-860 Titre : Autism and immune factors: A comprehensive review Type de document : Texte imprimé et/ou numérique Auteurs : Kimberly A. STIGLER, Auteur ; Thayne L. SWEETEN, Auteur ; Christopher J. MCDOUGLE, Auteur ; David J. POSEY, Auteur Année de publication : 2009 Article en page(s) : p.840-860 Langues : Anglais (eng) Mots-clés : Autism Immune Infection Immunogenetics Cytokines Gastrointestinal Autoimmune Index. décimale : PER Périodiques Résumé : Cases of autistic disorder (autism) have frequently been reported in association with congenital rubella and other infections. These observations stimulated further investigation into markers of immune function in autism. Postinfectious and autoimmune mechanisms of pathophysiology have been proposed. This review comprehensively addresses immune findings to date, including the role of viruses, neuroimmune factors, cellular and humoral immunity, immunogenetics, and immunotherapy in relation to autism. Although numerous immune abnormalities have been identified in autism, inconsistent results have often been reported. To date, research in this area has largely involved small, uncontrolled studies. In order to bring clarity to this field, high-quality, systematic research is needed to explore the role of neuroimmunologic factors in autism. En ligne : http://dx.doi.org/10.1016/j.rasd.2009.01.007 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=816 [article] Autism and immune factors: A comprehensive review [Texte imprimé et/ou numérique] / Kimberly A. STIGLER, Auteur ; Thayne L. SWEETEN, Auteur ; Christopher J. MCDOUGLE, Auteur ; David J. POSEY, Auteur . - 2009 . - p.840-860. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 3-4 (October-December 2009) . - p.840-860 Mots-clés : Autism Immune Infection Immunogenetics Cytokines Gastrointestinal Autoimmune Index. décimale : PER Périodiques Résumé : Cases of autistic disorder (autism) have frequently been reported in association with congenital rubella and other infections. These observations stimulated further investigation into markers of immune function in autism. Postinfectious and autoimmune mechanisms of pathophysiology have been proposed. This review comprehensively addresses immune findings to date, including the role of viruses, neuroimmune factors, cellular and humoral immunity, immunogenetics, and immunotherapy in relation to autism. Although numerous immune abnormalities have been identified in autism, inconsistent results have often been reported. To date, research in this area has largely involved small, uncontrolled studies. In order to bring clarity to this field, high-quality, systematic research is needed to explore the role of neuroimmunologic factors in autism. En ligne : http://dx.doi.org/10.1016/j.rasd.2009.01.007 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=816

Predictors and Moderators of Parent Training Efficacy in a Sample of Children with Autism Spectrum Disorders and Serious Behavioral Problems / Cristan A. FARMER in Journal of Autism and Developmental Disorders, 42-6 (June 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-6 (June 2012) . - p.1037-1044 Titre : Predictors and Moderators of Parent Training Efficacy in a Sample of Children with Autism Spectrum Disorders and Serious Behavioral Problems Type de document : Texte imprimé et/ou numérique Auteurs : Cristan A. FARMER, Auteur ; Luc LECAVALIER, Auteur ; Sunkyung YU, Auteur ; L. Eugene ARNOLD, Auteur ; Christopher J. MCDOUGLE, Auteur ; Lawrence SCAHILL, Auteur ; Benjamin L. HANDEN, Auteur ; Cynthia JOHNSON, Auteur ; Kimberly A. STIGLER, Auteur ; Karen E. BEARSS, Auteur ; Naomi SWIEZY, Auteur ; Michael G. AMAN, Auteur Année de publication : 2012 Article en page(s) : p.1037-1044 Langues : Anglais (eng) Mots-clés : Parent training  Pervasive developmental disorder  Autism  Risperidone  Predictor  Moderator Index. décimale : PER Périodiques Résumé : The Research Units on Pediatric Psychopharmacology—Autism Network reported additional benefit when adding parent training (PT) to antipsychotic medication in children with autism spectrum disorders and serious behavior problems. The intent-to-treat analyses were rerun with putative predictors and moderators. The Home Situations Questionnaire (HSQ) and the Hyperactivity/Noncompliance subscale of the Aberrant Behavior Checklist were used as outcome measures. Candidate predictors and moderators included 21 demographics and baseline measures of behavior. Higher baseline HSQ scores predicted greater improvement on the HSQ regardless of treatment assignment, but no other predictors of outcome were observed. None of the variables measured in this study moderated response to PT. Antipsychotic medication plus PT appears to be equally effective for children with a wide range of demographic and behavioral characteristics. En ligne : http://dx.doi.org/10.1007/s10803-011-1338-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=156 [article] Predictors and Moderators of Parent Training Efficacy in a Sample of Children with Autism Spectrum Disorders and Serious Behavioral Problems [Texte imprimé et/ou numérique] / Cristan A. FARMER, Auteur ; Luc LECAVALIER, Auteur ; Sunkyung YU, Auteur ; L. Eugene ARNOLD, Auteur ; Christopher J. MCDOUGLE, Auteur ; Lawrence SCAHILL, Auteur ; Benjamin L. HANDEN, Auteur ; Cynthia JOHNSON, Auteur ; Kimberly A. STIGLER, Auteur ; Karen E. BEARSS, Auteur ; Naomi SWIEZY, Auteur ; Michael G. AMAN, Auteur . - 2012 . - p.1037-1044. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-6 (June 2012) . - p.1037-1044 Mots-clés : Parent training  Pervasive developmental disorder  Autism  Risperidone  Predictor  Moderator Index. décimale : PER Périodiques Résumé : The Research Units on Pediatric Psychopharmacology—Autism Network reported additional benefit when adding parent training (PT) to antipsychotic medication in children with autism spectrum disorders and serious behavior problems. The intent-to-treat analyses were rerun with putative predictors and moderators. The Home Situations Questionnaire (HSQ) and the Hyperactivity/Noncompliance subscale of the Aberrant Behavior Checklist were used as outcome measures. Candidate predictors and moderators included 21 demographics and baseline measures of behavior. Higher baseline HSQ scores predicted greater improvement on the HSQ regardless of treatment assignment, but no other predictors of outcome were observed. None of the variables measured in this study moderated response to PT. Antipsychotic medication plus PT appears to be equally effective for children with a wide range of demographic and behavioral characteristics. En ligne : http://dx.doi.org/10.1007/s10803-011-1338-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=156

Psychopharmacological Treatment of Autism / Kelly BLANKENSHIP

Public ISBD in Autism Spectrum Disorders / David G. AMARAL Titre : Psychopharmacological Treatment of Autism Type de document : Texte imprimé et/ou numérique Auteurs : Kelly BLANKENSHIP, Auteur ; Craig ERICKSON, Auteur ; Kimberly A. STIGLER, Auteur ; David J. POSEY, Auteur ; Christopher J. MCDOUGLE, Auteur Année de publication : 2011 Importance : p.1196-1214 Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=140 in Autism Spectrum Disorders / David G. AMARAL Psychopharmacological Treatment of Autism [Texte imprimé et/ou numérique] / Kelly BLANKENSHIP, Auteur ; Craig ERICKSON, Auteur ; Kimberly A. STIGLER, Auteur ; David J. POSEY, Auteur ; Christopher J. MCDOUGLE, Auteur . - 2011 . - p.1196-1214. Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=140

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Psychopharmacology / Craig ERICKSON

Public ISBD contenu dans Autism and Pervasive Developmental Disorders / Fred R. VOLKMAR Titre : Psychopharmacology Type de document : Texte imprimé et/ou numérique Auteurs : Craig ERICKSON, Auteur ; Kimberly A. STIGLER, Auteur ; David J. POSEY, Auteur ; Christopher J. MCDOUGLE, Auteur Année de publication : 2007 Importance : p.221-253 Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=796 contenu dans Autism and Pervasive Developmental Disorders / Fred R. VOLKMAR Psychopharmacology [Texte imprimé et/ou numérique] / Craig ERICKSON, Auteur ; Kimberly A. STIGLER, Auteur ; David J. POSEY, Auteur ; Christopher J. MCDOUGLE, Auteur . - 2007 . - p.221-253. Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=796

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Structural and Functional MRI Studies of Autism Spectrum Disorders / Kimberly A. STIGLER

Public ISBD in The Neuroscience of Autism Spectrum Disorders / Joseph D. BUXBAUM Titre : Structural and Functional MRI Studies of Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Kimberly A. STIGLER, Auteur ; Christopher J. MCDOUGLE, Auteur Année de publication : 2013 Importance : p.251-266 Langues : Anglais (eng) Index. décimale : SCI-D SCI-D - Neurosciences Résumé : Structural and functional magnetic resonance imaging (MRI) research has significantly contributed to our understanding of the neurobiology of autism spectrum disorders (ASD). Structural MRI studies have demonstrated increased total brain volume, as well as an atypical trajectory of neurodevelopment in children with ASD. Differences in cortical gray and white matter volume have also been recorded in affected individuals, with diffusion tensor imaging revealing decreased white matter integrity at a microstructural level. Functional MRI research has found abnormalities in cortical activation and connectivity in ASD via task-based approaches. In addition, resting state studies have revealed atypical patterns of connectivity in the default-mode network. Despite these encouraging findings, additional large-scale neuroimaging studies are needed to further inform the neurobiological underpinnings of ASD. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=189 in The Neuroscience of Autism Spectrum Disorders / Joseph D. BUXBAUM Structural and Functional MRI Studies of Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Kimberly A. STIGLER, Auteur ; Christopher J. MCDOUGLE, Auteur . - 2013 . - p.251-266. Langues : Anglais (eng) Index. décimale : SCI-D SCI-D - Neurosciences Résumé : Structural and functional magnetic resonance imaging (MRI) research has significantly contributed to our understanding of the neurobiology of autism spectrum disorders (ASD). Structural MRI studies have demonstrated increased total brain volume, as well as an atypical trajectory of neurodevelopment in children with ASD. Differences in cortical gray and white matter volume have also been recorded in affected individuals, with diffusion tensor imaging revealing decreased white matter integrity at a microstructural level. Functional MRI research has found abnormalities in cortical activation and connectivity in ASD via task-based approaches. In addition, resting state studies have revealed atypical patterns of connectivity in the default-mode network. Despite these encouraging findings, additional large-scale neuroimaging studies are needed to further inform the neurobiological underpinnings of ASD. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=189

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The Neurochemistry of ASD / David J. POSEY

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Training of child and adolescent psychiatry fellows in autism and intellectual disability / Natasha MARRUS in Autism, 18-4 (May 2014)  

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Trial Design Challenges When Combining Medication and Parent Training in Children with Pervasive Developmental Disorders / Lawrence SCAHILL in Journal of Autism and Developmental Disorders, 39-5 (May 2009)  

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