[article]
Titre : |
Autism Traits in Individuals with Agenesis of the Corpus Callosum |
Type de document : |
Texte imprimé et/ou numérique |
Auteurs : |
Yolanda C. LAU, Auteur ; Leighton B N. HINKLEY, Auteur ; Polina BUKSHPUN, Auteur ; Zoe A. STROMINGER, Auteur ; Mari L. J. WAKAHIRO, Auteur ; Simon BARON-COHEN, Auteur ; Carrie ALLISON, Auteur ; Bonnie AUYEUNG, Auteur ; Rita J. JEREMY, Auteur ; Srikantan S. NAGARAJAN, Auteur ; Elliott H. SHERR, Auteur ; Elysa J. MARCO, Auteur |
Article en page(s) : |
p.1106-1118 |
Langues : |
Anglais (eng) |
Mots-clés : |
Agenesis of the corpus callosum Autism spectrum disorders Autism Spectrum Quotient Functional connectivity Magnetoencephalography Superior temporal gyrus |
Index. décimale : |
PER Périodiques |
Résumé : |
Autism spectrum disorders (ASD) have numerous etiologies, including structural brain malformations such as agenesis of the corpus callosum (AgCC). We sought to directly measure the occurrence of autism traits in a cohort of individuals with AgCC and to investigate the neural underpinnings of this association. We screened a large AgCC cohort (n = 106) with the Autism Spectrum Quotient (AQ) and found that 45 % of children, 35 % of adolescents, and 18 % of adults exceeded the predetermined autism-screening cut-off. Interestingly, performance on the AQ’s imagination domain was inversely correlated with magnetoencephalography measures of resting-state functional connectivity in the right superior temporal gyrus. Individuals with AgCC should be screened for ASD and disorders of the corpus callosum should be considered in autism diagnostic evaluations as well. |
En ligne : |
http://dx.doi.org/10.1007/s10803-012-1653-2 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=195 |
in Journal of Autism and Developmental Disorders > 43-5 (May 2013) . - p.1106-1118
[article] Autism Traits in Individuals with Agenesis of the Corpus Callosum [Texte imprimé et/ou numérique] / Yolanda C. LAU, Auteur ; Leighton B N. HINKLEY, Auteur ; Polina BUKSHPUN, Auteur ; Zoe A. STROMINGER, Auteur ; Mari L. J. WAKAHIRO, Auteur ; Simon BARON-COHEN, Auteur ; Carrie ALLISON, Auteur ; Bonnie AUYEUNG, Auteur ; Rita J. JEREMY, Auteur ; Srikantan S. NAGARAJAN, Auteur ; Elliott H. SHERR, Auteur ; Elysa J. MARCO, Auteur . - p.1106-1118. Langues : Anglais ( eng) in Journal of Autism and Developmental Disorders > 43-5 (May 2013) . - p.1106-1118 |